ARHGEF26 (Rho guanine nucleotide exchange factor 26)

Gene

• Entrez ID: 26084
• Gene name: Rho guanine nucleotide exchange factor 26
• Gene symbol: ARHGEF26
• Synonyms (NCBI Gene): CSGEF, HMFN1864, SGEF
• Chromosome: 3
• Chromosome location: 3q25.2
• Summary: This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024552	hsa-miR-215-5p	Microarray	19074876
MIRT026408	hsa-miR-192-5p	Microarray	19074876
MIRT090904	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT090905	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT090900	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT090901	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT090912	hsa-miR-3666	PAR-CLIP	21572407
MIRT090898	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT090910	hsa-miR-4295	PAR-CLIP	21572407
MIRT090907	hsa-miR-3121-3p	PAR-CLIP	21572407
MIRT090915	hsa-miR-3974	PAR-CLIP	21572407
MIRT090911	hsa-miR-4301	PAR-CLIP	21572407
MIRT559515	hsa-miR-3119	PAR-CLIP	21572407
MIRT090896	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT090897	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT559514	hsa-miR-124-3p	PAR-CLIP	21572407
MIRT559513	hsa-miR-506-3p	PAR-CLIP	21572407
MIRT090916	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT559512	hsa-miR-4473	PAR-CLIP	21572407
MIRT090899	hsa-miR-188-3p	PAR-CLIP	21572407
MIRT090906	hsa-miR-1260a	PAR-CLIP	21572407
MIRT090909	hsa-miR-1260b	PAR-CLIP	21572407
MIRT090908	hsa-miR-3156-3p	PAR-CLIP	21572407
MIRT090913	hsa-miR-4452	PAR-CLIP	21572407
MIRT559511	hsa-miR-3591-5p	PAR-CLIP	21572407
MIRT090904	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT090905	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT090900	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT090901	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT090912	hsa-miR-3666	PAR-CLIP	21572407
MIRT090898	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT090910	hsa-miR-4295	PAR-CLIP	21572407
MIRT090907	hsa-miR-3121-3p	PAR-CLIP	21572407
MIRT090915	hsa-miR-3974	PAR-CLIP	21572407
MIRT090911	hsa-miR-4301	PAR-CLIP	21572407
MIRT559515	hsa-miR-3119	PAR-CLIP	21572407
MIRT090896	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT090897	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT559514	hsa-miR-124-3p	PAR-CLIP	21572407
MIRT559513	hsa-miR-506-3p	PAR-CLIP	21572407
MIRT090916	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT559512	hsa-miR-4473	PAR-CLIP	21572407
MIRT090899	hsa-miR-188-3p	PAR-CLIP	21572407
MIRT090906	hsa-miR-1260a	PAR-CLIP	21572407
MIRT090909	hsa-miR-1260b	PAR-CLIP	21572407
MIRT090908	hsa-miR-3156-3p	PAR-CLIP	21572407
MIRT090913	hsa-miR-4452	PAR-CLIP	21572407
MIRT559511	hsa-miR-3591-5p	PAR-CLIP	21572407
MIRT795628	hsa-miR-1183	CLIP-seq
MIRT795629	hsa-miR-1208	CLIP-seq
MIRT795630	hsa-miR-1225-5p	CLIP-seq
MIRT795631	hsa-miR-125a-5p	CLIP-seq
MIRT795632	hsa-miR-125b	CLIP-seq
MIRT795633	hsa-miR-1268	CLIP-seq
MIRT795634	hsa-miR-1268b	CLIP-seq
MIRT795635	hsa-miR-1272	CLIP-seq
MIRT795636	hsa-miR-1273g	CLIP-seq
MIRT795637	hsa-miR-1285	CLIP-seq
MIRT795638	hsa-miR-130a	CLIP-seq
MIRT795639	hsa-miR-130b	CLIP-seq
MIRT795640	hsa-miR-147	CLIP-seq
MIRT795641	hsa-miR-1827	CLIP-seq
MIRT795642	hsa-miR-19a	CLIP-seq
MIRT795643	hsa-miR-19b	CLIP-seq
MIRT795644	hsa-miR-204	CLIP-seq
MIRT795645	hsa-miR-211	CLIP-seq
MIRT795646	hsa-miR-2276	CLIP-seq
MIRT795647	hsa-miR-24	CLIP-seq
MIRT795648	hsa-miR-2467-3p	CLIP-seq
MIRT795649	hsa-miR-301a	CLIP-seq
MIRT795650	hsa-miR-301b	CLIP-seq
MIRT795651	hsa-miR-3138	CLIP-seq
MIRT795652	hsa-miR-3148	CLIP-seq
MIRT795653	hsa-miR-3165	CLIP-seq
MIRT795654	hsa-miR-3168	CLIP-seq
MIRT795655	hsa-miR-3177-5p	CLIP-seq
MIRT795656	hsa-miR-3187-5p	CLIP-seq
MIRT795657	hsa-miR-34b	CLIP-seq
MIRT795658	hsa-miR-3545-3p	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT795660	hsa-miR-3616-3p	CLIP-seq
MIRT795661	hsa-miR-3616-5p	CLIP-seq
MIRT795662	hsa-miR-3619-3p	CLIP-seq
MIRT795663	hsa-miR-3647-5p	CLIP-seq
MIRT795664	hsa-miR-3664-3p	CLIP-seq
MIRT795665	hsa-miR-3667-3p	CLIP-seq
MIRT795666	hsa-miR-3680	CLIP-seq
MIRT795667	hsa-miR-3681	CLIP-seq
MIRT795668	hsa-miR-3689a-3p	CLIP-seq
MIRT795669	hsa-miR-3689c	CLIP-seq
MIRT795670	hsa-miR-3911	CLIP-seq
MIRT795671	hsa-miR-3926	CLIP-seq
MIRT795672	hsa-miR-3929	CLIP-seq
MIRT795673	hsa-miR-3940-3p	CLIP-seq
MIRT795674	hsa-miR-4257	CLIP-seq
MIRT795675	hsa-miR-4274	CLIP-seq
MIRT795676	hsa-miR-4284	CLIP-seq
MIRT795677	hsa-miR-4318	CLIP-seq
MIRT795678	hsa-miR-4319	CLIP-seq
MIRT795679	hsa-miR-4330	CLIP-seq
MIRT795680	hsa-miR-4419b	CLIP-seq
MIRT795681	hsa-miR-4420	CLIP-seq
MIRT795682	hsa-miR-4424	CLIP-seq
MIRT795683	hsa-miR-4433	CLIP-seq
MIRT795684	hsa-miR-4436b-3p	CLIP-seq
MIRT795685	hsa-miR-4440	CLIP-seq
MIRT795686	hsa-miR-4446-5p	CLIP-seq
MIRT795687	hsa-miR-4459	CLIP-seq
MIRT795688	hsa-miR-4476	CLIP-seq
MIRT795689	hsa-miR-4477b	CLIP-seq
MIRT795690	hsa-miR-4478	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT795692	hsa-miR-4505	CLIP-seq
MIRT795693	hsa-miR-4527	CLIP-seq
MIRT795694	hsa-miR-454	CLIP-seq
MIRT795695	hsa-miR-4649-3p	CLIP-seq
MIRT795696	hsa-miR-4653-3p	CLIP-seq
MIRT795697	hsa-miR-4693-5p	CLIP-seq
MIRT795698	hsa-miR-4695-3p	CLIP-seq
MIRT795699	hsa-miR-4699-3p	CLIP-seq
MIRT795700	hsa-miR-4721	CLIP-seq
MIRT795701	hsa-miR-4722-5p	CLIP-seq
MIRT795702	hsa-miR-4728-3p	CLIP-seq
MIRT795703	hsa-miR-4728-5p	CLIP-seq
MIRT795704	hsa-miR-4732-3p	CLIP-seq
MIRT795705	hsa-miR-4735-5p	CLIP-seq
MIRT795706	hsa-miR-4753-5p	CLIP-seq
MIRT795707	hsa-miR-4755-5p	CLIP-seq
MIRT795708	hsa-miR-4761-5p	CLIP-seq
MIRT795709	hsa-miR-4762-3p	CLIP-seq
MIRT795710	hsa-miR-4762-5p	CLIP-seq
MIRT795711	hsa-miR-4766-5p	CLIP-seq
MIRT795712	hsa-miR-4768-3p	CLIP-seq
MIRT795713	hsa-miR-4772-3p	CLIP-seq
MIRT795714	hsa-miR-4775	CLIP-seq
MIRT795715	hsa-miR-4776-5p	CLIP-seq
MIRT795716	hsa-miR-4777-3p	CLIP-seq
MIRT795717	hsa-miR-4778-5p	CLIP-seq
MIRT795718	hsa-miR-4786-5p	CLIP-seq
MIRT795719	hsa-miR-4793-5p	CLIP-seq
MIRT795720	hsa-miR-4795-5p	CLIP-seq
MIRT795721	hsa-miR-4798-3p	CLIP-seq
MIRT795722	hsa-miR-4800-5p	CLIP-seq
MIRT795723	hsa-miR-485-5p	CLIP-seq
MIRT795724	hsa-miR-502-5p	CLIP-seq
MIRT795725	hsa-miR-513c	CLIP-seq
MIRT795726	hsa-miR-514b-5p	CLIP-seq
MIRT795727	hsa-miR-517a	CLIP-seq
MIRT795728	hsa-miR-517b	CLIP-seq
MIRT795729	hsa-miR-517c	CLIP-seq
MIRT795730	hsa-miR-548a-3p	CLIP-seq
MIRT795731	hsa-miR-548a-5p	CLIP-seq
MIRT795732	hsa-miR-548ab	CLIP-seq
MIRT795733	hsa-miR-548ak	CLIP-seq
MIRT795734	hsa-miR-548b-5p	CLIP-seq
MIRT795735	hsa-miR-548c-5p	CLIP-seq
MIRT795736	hsa-miR-548d-5p	CLIP-seq
MIRT795737	hsa-miR-548e	CLIP-seq
MIRT795738	hsa-miR-548f	CLIP-seq
MIRT795739	hsa-miR-548h	CLIP-seq
MIRT795740	hsa-miR-548i	CLIP-seq
MIRT795741	hsa-miR-548j	CLIP-seq
MIRT795742	hsa-miR-548n	CLIP-seq
MIRT795743	hsa-miR-548s	CLIP-seq
MIRT795744	hsa-miR-548w	CLIP-seq
MIRT795745	hsa-miR-548y	CLIP-seq
MIRT795746	hsa-miR-559	CLIP-seq
MIRT795747	hsa-miR-561	CLIP-seq
MIRT795748	hsa-miR-562	CLIP-seq
MIRT795749	hsa-miR-564	CLIP-seq
MIRT795750	hsa-miR-573	CLIP-seq
MIRT795751	hsa-miR-585	CLIP-seq
MIRT795752	hsa-miR-590-3p	CLIP-seq
MIRT795753	hsa-miR-595	CLIP-seq
MIRT795754	hsa-miR-612	CLIP-seq
MIRT795755	hsa-miR-617	CLIP-seq
MIRT795756	hsa-miR-623	CLIP-seq
MIRT795757	hsa-miR-628-5p	CLIP-seq
MIRT795758	hsa-miR-644	CLIP-seq
MIRT795759	hsa-miR-670	CLIP-seq
MIRT795760	hsa-miR-767-3p	CLIP-seq
MIRT795761	hsa-miR-890	CLIP-seq
MIRT795762	hsa-miR-940	CLIP-seq
MIRT1934984	hsa-miR-1178	CLIP-seq
MIRT795628	hsa-miR-1183	CLIP-seq
MIRT1934985	hsa-miR-1202	CLIP-seq
MIRT1934986	hsa-miR-128	CLIP-seq
MIRT795637	hsa-miR-1285	CLIP-seq
MIRT1934987	hsa-miR-137	CLIP-seq
MIRT1934988	hsa-miR-142-3p	CLIP-seq
MIRT795642	hsa-miR-19a	CLIP-seq
MIRT795643	hsa-miR-19b	CLIP-seq
MIRT795644	hsa-miR-204	CLIP-seq
MIRT795645	hsa-miR-211	CLIP-seq
MIRT1934989	hsa-miR-22	CLIP-seq
MIRT1934990	hsa-miR-223	CLIP-seq
MIRT795647	hsa-miR-24	CLIP-seq
MIRT795648	hsa-miR-2467-3p	CLIP-seq
MIRT1934991	hsa-miR-27a	CLIP-seq
MIRT1934992	hsa-miR-27b	CLIP-seq
MIRT1934993	hsa-miR-3120-3p	CLIP-seq
MIRT1934994	hsa-miR-3126-5p	CLIP-seq
MIRT1934995	hsa-miR-3140-3p	CLIP-seq
MIRT1934996	hsa-miR-3143	CLIP-seq
MIRT795655	hsa-miR-3177-5p	CLIP-seq
MIRT795656	hsa-miR-3187-5p	CLIP-seq
MIRT1934997	hsa-miR-320a	CLIP-seq
MIRT1934998	hsa-miR-320b	CLIP-seq
MIRT1934999	hsa-miR-320c	CLIP-seq
MIRT1935000	hsa-miR-320d	CLIP-seq
MIRT1935001	hsa-miR-323b-3p	CLIP-seq
MIRT1935002	hsa-miR-330-3p	CLIP-seq
MIRT1935003	hsa-miR-331-5p	CLIP-seq
MIRT1935004	hsa-miR-340	CLIP-seq
MIRT1935005	hsa-miR-361-5p	CLIP-seq
MIRT795665	hsa-miR-3667-3p	CLIP-seq
MIRT1935006	hsa-miR-3671	CLIP-seq
MIRT795666	hsa-miR-3680	CLIP-seq
MIRT795672	hsa-miR-3929	CLIP-seq
MIRT1935007	hsa-miR-3972	CLIP-seq
MIRT1935008	hsa-miR-410	CLIP-seq
MIRT795674	hsa-miR-4257	CLIP-seq
MIRT795676	hsa-miR-4284	CLIP-seq
MIRT1935009	hsa-miR-4328	CLIP-seq
MIRT795679	hsa-miR-4330	CLIP-seq
MIRT795680	hsa-miR-4419b	CLIP-seq
MIRT1935010	hsa-miR-4427	CLIP-seq
MIRT1935011	hsa-miR-4429	CLIP-seq
MIRT795690	hsa-miR-4478	CLIP-seq
MIRT795692	hsa-miR-4505	CLIP-seq
MIRT1935012	hsa-miR-4522	CLIP-seq
MIRT1935013	hsa-miR-4640-5p	CLIP-seq
MIRT1935014	hsa-miR-4659a-5p	CLIP-seq
MIRT1935015	hsa-miR-4659b-5p	CLIP-seq
MIRT1935016	hsa-miR-4678	CLIP-seq
MIRT1935017	hsa-miR-4680-3p	CLIP-seq
MIRT1935018	hsa-miR-4691-5p	CLIP-seq
MIRT795697	hsa-miR-4693-5p	CLIP-seq
MIRT795698	hsa-miR-4695-3p	CLIP-seq
MIRT1935019	hsa-miR-4714-5p	CLIP-seq
MIRT1935020	hsa-miR-4724-3p	CLIP-seq
MIRT1935021	hsa-miR-4726-5p	CLIP-seq
MIRT1935022	hsa-miR-4738-3p	CLIP-seq
MIRT1935023	hsa-miR-4747-5p	CLIP-seq
MIRT795707	hsa-miR-4755-5p	CLIP-seq
MIRT1935024	hsa-miR-4760-3p	CLIP-seq
MIRT795708	hsa-miR-4761-5p	CLIP-seq
MIRT795711	hsa-miR-4766-5p	CLIP-seq
MIRT1935025	hsa-miR-4776-3p	CLIP-seq
MIRT1935026	hsa-miR-4795-3p	CLIP-seq
MIRT795721	hsa-miR-4798-3p	CLIP-seq
MIRT795724	hsa-miR-502-5p	CLIP-seq
MIRT1935027	hsa-miR-513a-5p	CLIP-seq
MIRT795725	hsa-miR-513c	CLIP-seq
MIRT795726	hsa-miR-514b-5p	CLIP-seq
MIRT1935028	hsa-miR-543	CLIP-seq
MIRT795749	hsa-miR-564	CLIP-seq
MIRT1935029	hsa-miR-607	CLIP-seq
MIRT795754	hsa-miR-612	CLIP-seq
MIRT795756	hsa-miR-623	CLIP-seq
MIRT1935030	hsa-miR-627	CLIP-seq
MIRT1935031	hsa-miR-648	CLIP-seq
MIRT795629	hsa-miR-1208	CLIP-seq
MIRT2174776	hsa-miR-1228	CLIP-seq
MIRT2174777	hsa-miR-1251	CLIP-seq
MIRT795631	hsa-miR-125a-5p	CLIP-seq
MIRT795632	hsa-miR-125b	CLIP-seq
MIRT2174778	hsa-miR-143	CLIP-seq
MIRT795641	hsa-miR-1827	CLIP-seq
MIRT2174779	hsa-miR-188-5p	CLIP-seq
MIRT2174780	hsa-miR-200b	CLIP-seq
MIRT2174781	hsa-miR-200c	CLIP-seq
MIRT2174782	hsa-miR-2110	CLIP-seq
MIRT2174783	hsa-miR-2116	CLIP-seq
MIRT2174784	hsa-miR-2278	CLIP-seq
MIRT795648	hsa-miR-2467-3p	CLIP-seq
MIRT2174785	hsa-miR-300	CLIP-seq
MIRT795651	hsa-miR-3138	CLIP-seq
MIRT1934995	hsa-miR-3140-3p	CLIP-seq
MIRT2174786	hsa-miR-3150a-3p	CLIP-seq
MIRT2174787	hsa-miR-3175	CLIP-seq
MIRT2174788	hsa-miR-3192	CLIP-seq
MIRT1935001	hsa-miR-323b-3p	CLIP-seq
MIRT795657	hsa-miR-34b	CLIP-seq
MIRT795658	hsa-miR-3545-3p	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT795661	hsa-miR-3616-5p	CLIP-seq
MIRT795662	hsa-miR-3619-3p	CLIP-seq
MIRT795663	hsa-miR-3647-5p	CLIP-seq
MIRT2174789	hsa-miR-3665	CLIP-seq
MIRT2174790	hsa-miR-3682-5p	CLIP-seq
MIRT795668	hsa-miR-3689a-3p	CLIP-seq
MIRT795669	hsa-miR-3689c	CLIP-seq
MIRT2174791	hsa-miR-375	CLIP-seq
MIRT2174792	hsa-miR-381	CLIP-seq
MIRT795672	hsa-miR-3929	CLIP-seq
MIRT2174793	hsa-miR-3934	CLIP-seq
MIRT795674	hsa-miR-4257	CLIP-seq
MIRT2174794	hsa-miR-4266	CLIP-seq
MIRT2174795	hsa-miR-4269	CLIP-seq
MIRT2174796	hsa-miR-4273	CLIP-seq
MIRT2174797	hsa-miR-429	CLIP-seq
MIRT2174798	hsa-miR-4293	CLIP-seq
MIRT795677	hsa-miR-4318	CLIP-seq
MIRT795678	hsa-miR-4319	CLIP-seq
MIRT795680	hsa-miR-4419b	CLIP-seq
MIRT795681	hsa-miR-4420	CLIP-seq
MIRT2174799	hsa-miR-4468	CLIP-seq
MIRT795688	hsa-miR-4476	CLIP-seq
MIRT795690	hsa-miR-4478	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT2174800	hsa-miR-4639-5p	CLIP-seq
MIRT2174801	hsa-miR-4645-5p	CLIP-seq
MIRT795695	hsa-miR-4649-3p	CLIP-seq
MIRT2174802	hsa-miR-4666-3p	CLIP-seq
MIRT2174803	hsa-miR-4673	CLIP-seq
MIRT2174804	hsa-miR-4677-5p	CLIP-seq
MIRT1935018	hsa-miR-4691-5p	CLIP-seq
MIRT2174805	hsa-miR-4695-5p	CLIP-seq
MIRT795701	hsa-miR-4722-5p	CLIP-seq
MIRT795703	hsa-miR-4728-5p	CLIP-seq
MIRT795704	hsa-miR-4732-3p	CLIP-seq
MIRT1935022	hsa-miR-4738-3p	CLIP-seq
MIRT2174806	hsa-miR-4755-3p	CLIP-seq
MIRT2174807	hsa-miR-4756-3p	CLIP-seq
MIRT795712	hsa-miR-4768-3p	CLIP-seq
MIRT2174808	hsa-miR-4770	CLIP-seq
MIRT795715	hsa-miR-4776-5p	CLIP-seq
MIRT795717	hsa-miR-4778-5p	CLIP-seq
MIRT2174809	hsa-miR-4779	CLIP-seq
MIRT795720	hsa-miR-4795-5p	CLIP-seq
MIRT795722	hsa-miR-4800-5p	CLIP-seq
MIRT795723	hsa-miR-485-5p	CLIP-seq
MIRT795750	hsa-miR-573	CLIP-seq
MIRT2174810	hsa-miR-589	CLIP-seq
MIRT2174811	hsa-miR-596	CLIP-seq
MIRT1935030	hsa-miR-627	CLIP-seq
MIRT2174812	hsa-miR-661	CLIP-seq
MIRT795759	hsa-miR-670	CLIP-seq
MIRT2174813	hsa-miR-765	CLIP-seq
MIRT795760	hsa-miR-767-3p	CLIP-seq
MIRT2174814	hsa-miR-939	CLIP-seq
MIRT795762	hsa-miR-940	CLIP-seq
MIRT1934985	hsa-miR-1202	CLIP-seq
MIRT2174777	hsa-miR-1251	CLIP-seq
MIRT2443943	hsa-miR-1273	CLIP-seq
MIRT1934987	hsa-miR-137	CLIP-seq
MIRT2174782	hsa-miR-2110	CLIP-seq
MIRT2174786	hsa-miR-3150a-3p	CLIP-seq
MIRT2174787	hsa-miR-3175	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT1935007	hsa-miR-3972	CLIP-seq
MIRT2174798	hsa-miR-4293	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT2443944	hsa-miR-4517	CLIP-seq
MIRT2443945	hsa-miR-4649-5p	CLIP-seq
MIRT2174811	hsa-miR-596	CLIP-seq
MIRT2174812	hsa-miR-661	CLIP-seq
MIRT2174814	hsa-miR-939	CLIP-seq
MIRT2478163	hsa-miR-10a	CLIP-seq
MIRT2478164	hsa-miR-10b	CLIP-seq
MIRT795633	hsa-miR-1268	CLIP-seq
MIRT795634	hsa-miR-1268b	CLIP-seq
MIRT795635	hsa-miR-1272	CLIP-seq
MIRT2174782	hsa-miR-2110	CLIP-seq
MIRT2174786	hsa-miR-3150a-3p	CLIP-seq
MIRT2174787	hsa-miR-3175	CLIP-seq
MIRT2478165	hsa-miR-339-5p	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT795671	hsa-miR-3926	CLIP-seq
MIRT2478166	hsa-miR-4421	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT2478167	hsa-miR-4684-5p	CLIP-seq
MIRT795718	hsa-miR-4786-5p	CLIP-seq
MIRT795719	hsa-miR-4793-5p	CLIP-seq
MIRT795742	hsa-miR-548n	CLIP-seq
MIRT795743	hsa-miR-548s	CLIP-seq
MIRT795748	hsa-miR-562	CLIP-seq
MIRT795751	hsa-miR-585	CLIP-seq
MIRT2478168	hsa-miR-593	CLIP-seq
MIRT2174814	hsa-miR-939	CLIP-seq
MIRT2478163	hsa-miR-10a	CLIP-seq
MIRT2478164	hsa-miR-10b	CLIP-seq
MIRT795635	hsa-miR-1272	CLIP-seq
MIRT2675316	hsa-miR-149	CLIP-seq
MIRT795647	hsa-miR-24	CLIP-seq
MIRT2478165	hsa-miR-339-5p	CLIP-seq
MIRT795671	hsa-miR-3926	CLIP-seq
MIRT795676	hsa-miR-4284	CLIP-seq
MIRT2675317	hsa-miR-4317	CLIP-seq
MIRT2478166	hsa-miR-4421	CLIP-seq
MIRT2478167	hsa-miR-4684-5p	CLIP-seq
MIRT795718	hsa-miR-4786-5p	CLIP-seq
MIRT795719	hsa-miR-4793-5p	CLIP-seq
MIRT2675318	hsa-miR-542-3p	CLIP-seq
MIRT795743	hsa-miR-548s	CLIP-seq
MIRT2478168	hsa-miR-593	CLIP-seq
MIRT2675319	hsa-miR-892b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001726	Component	Ruffle	IEA
GO:0001886	Process	Endothelial cell morphogenesis	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0032956	Process	Regulation of actin cytoskeleton organization	IBA
GO:0042995	Component	Cell projection	IEA
GO:0097178	Process	Ruffle assembly	IEA

Other IDs

• MIM: 617552
• HGNC: 24490
• e!Ensembl: ENSG00000114790

Protein

• UniProt ID: Q96DR7
• Protein name: Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)
• Protein function: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of
• PDB: 6MYE, 7YKG
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00621	RhoGEF	443 → 621	RhoGEF domain	Domain
  PF00018	SH3_1	799 → 842	SH3 domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Isoform 1 is broadly expressed, with highest levels in liver (at protein level). Certain mRNA species appear to be specifically expressed in prostate and liver. {ECO:0000269|PubMed:12697679, ECO:0000269|PubMed:15133129}.
• Sequence:

  MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLL
  AAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAV
  PGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAA
  NNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSP
  AALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDN
  DVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRI
  KKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQ
  LSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTER
  HHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQ
  RTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDS
  PKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRG
  ELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNE
  ELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHS
  SGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWF
  PMECAKEITCQATIDKNVERMGRLLGLETNV

• Sequence length: 871

Pathways

KEGG:

Bacterial invasion of epithelial cells
Salmonella infection

Reactome:

NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AORTIC STENOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GOUT	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Marfanoid habitus and intellectual disability	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Arteriosclerosis	Arteriosclerosis	BEFREE	23372835		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	23372835		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	28202690	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	34301206	Associate	★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	31886187	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	31159706	Associate	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	BEFREE	28584231		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Coronary Artery Disease	Coronary artery disease	Pubtator	28584231	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Coronary Artery Disease	Coronary artery disease	GWASCAT_DG	28714974, 28714975, 29212778		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	35003396	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	35003396	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	23775076, 26764186		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	23775076, 26764186	Stimulate	★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	23775076, 26764186		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	23775076, 26764186		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	23775076, 26764186, 29454349	Associate	★☆☆☆☆ Found in Text Mining only
Leigh syndrome French Canadian type	Leigh syndrome	Pubtator	29454349	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	23775076, 26764186		★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	37378023	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	29454349	Associate	★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	GWASCAT_DG	26198764		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Vascular Diseases	Vascular disease	Pubtator	36928188	Associate	★☆☆☆☆ Found in Text Mining only