LRP10 (LDL receptor related protein 10)

Gene

• Entrez ID: 26020
• Gene name: LDL receptor related protein 10
• Gene symbol: LRP10
• Synonyms (NCBI Gene): LRP-10, LRP9, MST087, MSTP087
• Chromosome: 14
• Chromosome location: 14q11.2
• Summary: This gene encodes a low density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. [provided by RefSeq, Jul 2016]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019186	hsa-miR-335-5p	Microarray	18185580
MIRT023152	hsa-miR-124-3p	Microarray	18668037
MIRT048363	hsa-miR-29b-3p	CLASH	23622248
MIRT046674	hsa-miR-222-3p	CLASH	23622248
MIRT717785	hsa-miR-548b-3p	HITS-CLIP	19536157
MIRT717784	hsa-miR-4511	HITS-CLIP	19536157
MIRT717783	hsa-miR-5003-3p	HITS-CLIP	19536157
MIRT717785	hsa-miR-548b-3p	HITS-CLIP	19536157
MIRT717784	hsa-miR-4511	HITS-CLIP	19536157
MIRT717783	hsa-miR-5003-3p	HITS-CLIP	19536157
MIRT679244	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT679243	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT679242	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT679241	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT679240	hsa-miR-4532	HITS-CLIP	23824327
MIRT679239	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT679238	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679237	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679236	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679235	hsa-miR-1281	HITS-CLIP	23824327
MIRT679234	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679233	hsa-miR-1976	HITS-CLIP	23824327
MIRT635430	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679232	hsa-miR-4279	HITS-CLIP	23824327
MIRT679231	hsa-miR-516a-5p	HITS-CLIP	23824327
MIRT679230	hsa-miR-498	HITS-CLIP	23824327
MIRT635438	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT635437	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635436	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT635435	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT635434	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635432	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT635433	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635431	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT635430	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT635429	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635428	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635427	hsa-miR-4634	HITS-CLIP	23824327
MIRT635426	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT635425	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT635424	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT635423	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT635438	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT635437	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635436	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT635435	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT635434	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635432	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT635433	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635431	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT635430	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT635429	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635428	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635427	hsa-miR-4634	HITS-CLIP	23824327
MIRT635426	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT635425	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT635424	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT635423	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT456950	hsa-miR-3929	PAR-CLIP	23592263
MIRT456951	hsa-miR-4419b	PAR-CLIP	23592263
MIRT456949	hsa-miR-4478	PAR-CLIP	23592263
MIRT456948	hsa-miR-9500	PAR-CLIP	23592263
MIRT456947	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT456946	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT456945	hsa-miR-7113-5p	PAR-CLIP	23592263
MIRT456944	hsa-miR-4685-5p	PAR-CLIP	23592263
MIRT456943	hsa-miR-6837-5p	PAR-CLIP	23592263
MIRT456942	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT456941	hsa-miR-4795-5p	PAR-CLIP	23592263
MIRT456940	hsa-miR-485-5p	PAR-CLIP	23592263
MIRT456939	hsa-miR-6884-5p	PAR-CLIP	23592263
MIRT456938	hsa-miR-4533	PAR-CLIP	23592263
MIRT456937	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT456936	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT456935	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT456934	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT456933	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT456932	hsa-miR-8071	PAR-CLIP	23592263
MIRT456931	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT456930	hsa-miR-3165	PAR-CLIP	23592263
MIRT456929	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT456928	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT717785	hsa-miR-548b-3p	HITS-CLIP	19536157
MIRT717784	hsa-miR-4511	HITS-CLIP	19536157
MIRT717783	hsa-miR-5003-3p	HITS-CLIP	19536157
MIRT717785	hsa-miR-548b-3p	HITS-CLIP	19536157
MIRT717784	hsa-miR-4511	HITS-CLIP	19536157
MIRT717783	hsa-miR-5003-3p	HITS-CLIP	19536157
MIRT679244	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT679243	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT679242	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT679241	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT679240	hsa-miR-4532	HITS-CLIP	23824327
MIRT679239	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT679238	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679237	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679236	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679235	hsa-miR-1281	HITS-CLIP	23824327
MIRT679234	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679233	hsa-miR-1976	HITS-CLIP	23824327
MIRT635430	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679232	hsa-miR-4279	HITS-CLIP	23824327
MIRT679231	hsa-miR-516a-5p	HITS-CLIP	23824327
MIRT679230	hsa-miR-498	HITS-CLIP	23824327
MIRT635438	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT635437	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635436	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT635435	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT635434	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635432	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT635433	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635431	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT635430	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT635429	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635428	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635427	hsa-miR-4634	HITS-CLIP	23824327
MIRT635426	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT635425	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT635424	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT635423	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT635438	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT635437	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT635436	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT635435	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT635434	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT635432	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT635433	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT635431	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT635430	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT635429	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT635428	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT635427	hsa-miR-4634	HITS-CLIP	23824327
MIRT635426	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT635425	hsa-miR-4774-3p	HITS-CLIP	23824327
MIRT635424	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT635423	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT456950	hsa-miR-3929	PAR-CLIP	23592263
MIRT456951	hsa-miR-4419b	PAR-CLIP	23592263
MIRT456949	hsa-miR-4478	PAR-CLIP	23592263
MIRT456948	hsa-miR-9500	PAR-CLIP	23592263
MIRT456947	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT456946	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT456945	hsa-miR-7113-5p	PAR-CLIP	23592263
MIRT456944	hsa-miR-4685-5p	PAR-CLIP	23592263
MIRT456943	hsa-miR-6837-5p	PAR-CLIP	23592263
MIRT456942	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT456941	hsa-miR-4795-5p	PAR-CLIP	23592263
MIRT456940	hsa-miR-485-5p	PAR-CLIP	23592263
MIRT456939	hsa-miR-6884-5p	PAR-CLIP	23592263
MIRT456938	hsa-miR-4533	PAR-CLIP	23592263
MIRT456937	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT456936	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT456935	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT456934	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT456933	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT456932	hsa-miR-8071	PAR-CLIP	23592263
MIRT456931	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT456930	hsa-miR-3165	PAR-CLIP	23592263
MIRT456929	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT456928	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT1117762	hsa-miR-1231	CLIP-seq
MIRT1117763	hsa-miR-3150b-3p	CLIP-seq
MIRT1117764	hsa-miR-3176	CLIP-seq
MIRT1117765	hsa-miR-3179	CLIP-seq
MIRT1117766	hsa-miR-3187-3p	CLIP-seq
MIRT1117767	hsa-miR-3199	CLIP-seq
MIRT1117768	hsa-miR-323-5p	CLIP-seq
MIRT1117769	hsa-miR-342-5p	CLIP-seq
MIRT1117770	hsa-miR-3664-5p	CLIP-seq
MIRT1117771	hsa-miR-3665	CLIP-seq
MIRT1117772	hsa-miR-3922-3p	CLIP-seq
MIRT1117773	hsa-miR-4475	CLIP-seq
MIRT1117774	hsa-miR-4515	CLIP-seq
MIRT1117775	hsa-miR-4522	CLIP-seq
MIRT1117776	hsa-miR-4529-5p	CLIP-seq
MIRT1117777	hsa-miR-4651	CLIP-seq
MIRT1117778	hsa-miR-4664-5p	CLIP-seq
MIRT1117779	hsa-miR-4677-3p	CLIP-seq
MIRT1117780	hsa-miR-4679	CLIP-seq
MIRT1117781	hsa-miR-4701-5p	CLIP-seq
MIRT1117782	hsa-miR-4784	CLIP-seq
MIRT1117783	hsa-miR-4797-5p	CLIP-seq
MIRT1117784	hsa-miR-588	CLIP-seq
MIRT1117785	hsa-miR-608	CLIP-seq
MIRT1117786	hsa-miR-876-3p	CLIP-seq
MIRT1117762	hsa-miR-1231	CLIP-seq
MIRT1117764	hsa-miR-3176	CLIP-seq
MIRT1117765	hsa-miR-3179	CLIP-seq
MIRT1117766	hsa-miR-3187-3p	CLIP-seq
MIRT1117767	hsa-miR-3199	CLIP-seq
MIRT1117768	hsa-miR-323-5p	CLIP-seq
MIRT1117769	hsa-miR-342-5p	CLIP-seq
MIRT1117771	hsa-miR-3665	CLIP-seq
MIRT1550908	hsa-miR-3688-3p	CLIP-seq
MIRT1550909	hsa-miR-3908	CLIP-seq
MIRT1117772	hsa-miR-3922-3p	CLIP-seq
MIRT1117773	hsa-miR-4475	CLIP-seq
MIRT1117774	hsa-miR-4515	CLIP-seq
MIRT1117776	hsa-miR-4529-5p	CLIP-seq
MIRT1117777	hsa-miR-4651	CLIP-seq
MIRT1117778	hsa-miR-4664-5p	CLIP-seq
MIRT1117781	hsa-miR-4701-5p	CLIP-seq
MIRT1117784	hsa-miR-588	CLIP-seq
MIRT1117785	hsa-miR-608	CLIP-seq
MIRT1117786	hsa-miR-876-3p	CLIP-seq
MIRT2033278	hsa-miR-1225-5p	CLIP-seq
MIRT2033279	hsa-miR-1252	CLIP-seq
MIRT2033280	hsa-miR-1271	CLIP-seq
MIRT2033281	hsa-miR-182	CLIP-seq
MIRT2033282	hsa-miR-2113	CLIP-seq
MIRT2033283	hsa-miR-3132	CLIP-seq
MIRT2033284	hsa-miR-4325	CLIP-seq
MIRT2033285	hsa-miR-4451	CLIP-seq
MIRT2033286	hsa-miR-4464	CLIP-seq
MIRT2033287	hsa-miR-4684-3p	CLIP-seq
MIRT2033288	hsa-miR-4691-3p	CLIP-seq
MIRT2033289	hsa-miR-4748	CLIP-seq
MIRT2033290	hsa-miR-522	CLIP-seq
MIRT2033291	hsa-miR-548ac	CLIP-seq
MIRT2033292	hsa-miR-548ae	CLIP-seq
MIRT2033293	hsa-miR-548aj	CLIP-seq
MIRT2033294	hsa-miR-548am	CLIP-seq
MIRT2033295	hsa-miR-548d-3p	CLIP-seq
MIRT2033296	hsa-miR-548x	CLIP-seq
MIRT2033297	hsa-miR-548z	CLIP-seq
MIRT2033298	hsa-miR-96	CLIP-seq
MIRT2263633	hsa-miR-1182	CLIP-seq
MIRT2263634	hsa-miR-122	CLIP-seq
MIRT2263635	hsa-miR-1225-3p	CLIP-seq
MIRT2033278	hsa-miR-1225-5p	CLIP-seq
MIRT2033279	hsa-miR-1252	CLIP-seq
MIRT2033280	hsa-miR-1271	CLIP-seq
MIRT2263636	hsa-miR-15a	CLIP-seq
MIRT2263637	hsa-miR-15b	CLIP-seq
MIRT2263638	hsa-miR-16	CLIP-seq
MIRT2033281	hsa-miR-182	CLIP-seq
MIRT2263639	hsa-miR-195	CLIP-seq
MIRT2263640	hsa-miR-198	CLIP-seq
MIRT2263641	hsa-miR-221	CLIP-seq
MIRT2263642	hsa-miR-222	CLIP-seq
MIRT2263643	hsa-miR-2392	CLIP-seq
MIRT2263644	hsa-miR-31	CLIP-seq
MIRT2033283	hsa-miR-3132	CLIP-seq
MIRT2263645	hsa-miR-3150a-3p	CLIP-seq
MIRT2263646	hsa-miR-3175	CLIP-seq
MIRT1117765	hsa-miR-3179	CLIP-seq
MIRT1117768	hsa-miR-323-5p	CLIP-seq
MIRT1117771	hsa-miR-3665	CLIP-seq
MIRT2263647	hsa-miR-376c	CLIP-seq
MIRT2263648	hsa-miR-424	CLIP-seq
MIRT2033285	hsa-miR-4451	CLIP-seq
MIRT2033286	hsa-miR-4464	CLIP-seq
MIRT1117773	hsa-miR-4475	CLIP-seq
MIRT2263649	hsa-miR-4524	CLIP-seq
MIRT2263650	hsa-miR-4534	CLIP-seq
MIRT2263651	hsa-miR-4717-5p	CLIP-seq
MIRT2263652	hsa-miR-4720-3p	CLIP-seq
MIRT2033289	hsa-miR-4748	CLIP-seq
MIRT2263653	hsa-miR-4753-5p	CLIP-seq
MIRT2263654	hsa-miR-4804-3p	CLIP-seq
MIRT2263655	hsa-miR-491-5p	CLIP-seq
MIRT2263656	hsa-miR-497	CLIP-seq
MIRT2263657	hsa-miR-503	CLIP-seq
MIRT2033290	hsa-miR-522	CLIP-seq
MIRT2263658	hsa-miR-646	CLIP-seq
MIRT1117786	hsa-miR-876-3p	CLIP-seq
MIRT2263659	hsa-miR-939	CLIP-seq
MIRT2033298	hsa-miR-96	CLIP-seq
MIRT2263645	hsa-miR-3150a-3p	CLIP-seq
MIRT2263646	hsa-miR-3175	CLIP-seq
MIRT1117768	hsa-miR-323-5p	CLIP-seq
MIRT1117771	hsa-miR-3665	CLIP-seq
MIRT2263655	hsa-miR-491-5p	CLIP-seq
MIRT1117786	hsa-miR-876-3p	CLIP-seq
MIRT2263659	hsa-miR-939	CLIP-seq
MIRT2263633	hsa-miR-1182	CLIP-seq
MIRT2562923	hsa-miR-1224-3p	CLIP-seq
MIRT2263635	hsa-miR-1225-3p	CLIP-seq
MIRT2562924	hsa-miR-1227	CLIP-seq
MIRT2263636	hsa-miR-15a	CLIP-seq
MIRT2263637	hsa-miR-15b	CLIP-seq
MIRT2263638	hsa-miR-16	CLIP-seq
MIRT2562925	hsa-miR-1915	CLIP-seq
MIRT2263639	hsa-miR-195	CLIP-seq
MIRT2263641	hsa-miR-221	CLIP-seq
MIRT2263642	hsa-miR-222	CLIP-seq
MIRT2263646	hsa-miR-3175	CLIP-seq
MIRT2562926	hsa-miR-361-3p	CLIP-seq
MIRT2263647	hsa-miR-376c	CLIP-seq
MIRT2562927	hsa-miR-3943	CLIP-seq
MIRT2263648	hsa-miR-424	CLIP-seq
MIRT2562928	hsa-miR-4252	CLIP-seq
MIRT2263649	hsa-miR-4524	CLIP-seq
MIRT2562929	hsa-miR-4732-5p	CLIP-seq
MIRT2263656	hsa-miR-497	CLIP-seq
MIRT2263657	hsa-miR-503	CLIP-seq
MIRT2263658	hsa-miR-646	CLIP-seq
MIRT2562930	hsa-miR-95	CLIP-seq
MIRT2263633	hsa-miR-1182	CLIP-seq
MIRT2562923	hsa-miR-1224-3p	CLIP-seq
MIRT2263635	hsa-miR-1225-3p	CLIP-seq
MIRT2562924	hsa-miR-1227	CLIP-seq
MIRT2033279	hsa-miR-1252	CLIP-seq
MIRT2684133	hsa-miR-125a-5p	CLIP-seq
MIRT2684134	hsa-miR-125b	CLIP-seq
MIRT2263636	hsa-miR-15a	CLIP-seq
MIRT2263637	hsa-miR-15b	CLIP-seq
MIRT2263638	hsa-miR-16	CLIP-seq
MIRT2562925	hsa-miR-1915	CLIP-seq
MIRT2263639	hsa-miR-195	CLIP-seq
MIRT2684135	hsa-miR-2114	CLIP-seq
MIRT2263641	hsa-miR-221	CLIP-seq
MIRT2263642	hsa-miR-222	CLIP-seq
MIRT2263646	hsa-miR-3175	CLIP-seq
MIRT2562926	hsa-miR-361-3p	CLIP-seq
MIRT2684136	hsa-miR-3691-3p	CLIP-seq
MIRT2263647	hsa-miR-376c	CLIP-seq
MIRT2562927	hsa-miR-3943	CLIP-seq
MIRT2263648	hsa-miR-424	CLIP-seq
MIRT2562928	hsa-miR-4252	CLIP-seq
MIRT2684137	hsa-miR-4319	CLIP-seq
MIRT2263649	hsa-miR-4524	CLIP-seq
MIRT2684138	hsa-miR-4732-3p	CLIP-seq
MIRT2562929	hsa-miR-4732-5p	CLIP-seq
MIRT2263656	hsa-miR-497	CLIP-seq
MIRT2263657	hsa-miR-503	CLIP-seq
MIRT2263658	hsa-miR-646	CLIP-seq
MIRT2684139	hsa-miR-670	CLIP-seq
MIRT2562930	hsa-miR-95	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005041	Function	Low-density lipoprotein particle receptor activity	IBA
GO:0005041	Function	Low-density lipoprotein particle receptor activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005905	Component	Clathrin-coated pit	IEA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006869	Process	Lipid transport	IEA
GO:0006897	Process	Endocytosis	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0048839	Process	Inner ear development	IEA

Other IDs

• MIM: 609921
• HGNC: 14553
• e!Ensembl: ENSG00000197324

Protein

• UniProt ID: Q7Z4F1
• Protein name: Low-density lipoprotein receptor-related protein 10 (LRP-10)
• Protein function: Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00057	Ldl_recept_a	138 → 174	Low-density lipoprotein receptor domain class A	Repeat
  PF00431	CUB	192 → 302	CUB domain	Domain
  PF00057	Ldl_recept_a	397 → 433	Low-density lipoprotein receptor domain class A	Repeat

• Tissue specificity: TISSUE SPECIFICITY: Expressed in blood leukocyte, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle and heart. {ECO:0000269|PubMed:11123907}.
• Sequence:

  MLLATLLLLLLGGALAHPDRIIFPNHACEDPPAVLLEVQGTLQRPLVRDSRTSPANCTWL
  ILGSKEQTVTIRFQKLHLACGSERLTLRSPLQPLISLCEAPPSPLQLPGGNVTITYSYAG
  ARAPMGQGFLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCDGVDACGDGSDEAGCSSDPFP
  GLTPRPVPSLPCNVTLEDFYGVFSSPGYTHLASVSHPQSCHWLLDPHDGRRLAVRFTALD
  LGFGDAVHVYDGPGPPESSRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSNGRGFNA
  TYHVRGYCLPWDRPCGLGSGLGAGEGLGERCYSEAQRCDGSWDCADGTDEEDCPGCPPGH
  FPCGAAGTSGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDG
  QPDCADGSDEWDCSYVLPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPL
  SRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGG
  GPGARRRQRGRLMRRLVRRLRRWGLLPRTNTPARASEARSQVTPSAAPLEALDGGTGPAR
  EGGAVGGQDGEQAPPLPIKAPLPSASTSPAPTTVPEAPGPLPSLPLEPSLLSGVVQALRG
  RLLPSLGPPGPTRSPPGPHTAVLALEDEDDVLLVPLAEPGVWVAEAEDEPLLT

• Sequence length: 713

Pathways

Reactome:

Retinoid metabolism and transport

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BLADDER EXSTROPHY AND EPISPADIAS COMPLEX	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bladder exstrophy-epispadias-cloacal extrophy complex	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LRP10-related disorder	Benign; Likely benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Myoepithelial tumor	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of pancreas	Pancreatic adenocarcinoma	BEFREE	29088295		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	32597809	Associate	★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic lateral sclerosis	Pubtator	33913039	Associate	★☆☆☆☆ Found in Text Mining only
Aortic Aneurysm, Abdominal	Aortic Aneurysm	BEFREE	29887161		★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	29088295	Associate	★☆☆☆☆ Found in Text Mining only
Cerebral Hemorrhage	Cerebral hemorrhage	Pubtator	30836997	Associate	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	Pubtator	34565095	Associate	★☆☆☆☆ Found in Text Mining only
Dementia	Dementia	BEFREE	30964957		★☆☆☆☆ Found in Text Mining only
Dementia	Dementia	Pubtator	32597809	Associate	★☆☆☆☆ Found in Text Mining only
Lewy Body Disease	Lewy Body Disease	BEFREE	29887161, 30964957, 31147221		★☆☆☆☆ Found in Text Mining only
Lewy Body Disease	Lewy body disease	Pubtator	32527607, 32597809, 33913039	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	29088295		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	22734645		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	37894825	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	29088295	Associate	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	29887161, 30964957, 31147221		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	32527607, 32597809, 33913039, 38460235	Associate	★☆☆☆☆ Found in Text Mining only
Presenile dementia	Senile Dementia	BEFREE	30964957		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	37894825	Associate	★☆☆☆☆ Found in Text Mining only
Supranuclear Palsy Progressive	Progressive supranuclear palsy	Pubtator	32527607, 33913039, 35842134	Associate	★☆☆☆☆ Found in Text Mining only