Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	25896
Gene name	Integrator complex subunit 7
Gene symbol	INTS7
Synonyms (NCBI Gene)	C1orf73INT7
Chromosome	1
Chromosome location	1q32.3
Summary	This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3`-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020750	hsa-miR-155-5p	Proteomics	18668040
MIRT029468	hsa-miR-26b-5p	Microarray	19088304
MIRT032348	hsa-let-7b-5p	Proteomics	18668040
MIRT684476	hsa-miR-7153-3p	HITS-CLIP	23313552
MIRT684475	hsa-miR-589-3p	HITS-CLIP	23313552
MIRT684474	hsa-miR-490-5p	HITS-CLIP	23313552
MIRT684473	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT684472	hsa-miR-6801-5p	HITS-CLIP	23313552
MIRT684471	hsa-miR-6073	HITS-CLIP	23313552
MIRT684470	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT684469	hsa-miR-134-5p	HITS-CLIP	23313552
MIRT684468	hsa-miR-3118	HITS-CLIP	23313552
MIRT684467	hsa-miR-1261	HITS-CLIP	23313552
MIRT681153	hsa-miR-3927-3p	HITS-CLIP	23706177
MIRT681152	hsa-miR-6831-5p	HITS-CLIP	23706177
MIRT681151	hsa-miR-181d-3p	HITS-CLIP	23706177
MIRT681150	hsa-miR-1203	HITS-CLIP	23706177
MIRT681149	hsa-miR-3192-5p	HITS-CLIP	23706177
MIRT681148	hsa-miR-5186	HITS-CLIP	23706177
MIRT681147	hsa-miR-3160-3p	HITS-CLIP	23706177
MIRT681146	hsa-miR-558	HITS-CLIP	23706177
MIRT681145	hsa-miR-4487	HITS-CLIP	23706177
MIRT681144	hsa-let-7a-5p	HITS-CLIP	23706177
MIRT032348	hsa-let-7b-5p	HITS-CLIP	23706177
MIRT681143	hsa-let-7c-5p	HITS-CLIP	23706177
MIRT681142	hsa-let-7d-5p	HITS-CLIP	23706177
MIRT681141	hsa-let-7e-5p	HITS-CLIP	23706177
MIRT681140	hsa-let-7f-5p	HITS-CLIP	23706177
MIRT681139	hsa-let-7g-5p	HITS-CLIP	23706177
MIRT681138	hsa-let-7i-5p	HITS-CLIP	23706177
MIRT681137	hsa-miR-4458	HITS-CLIP	23706177
MIRT681136	hsa-miR-4500	HITS-CLIP	23706177
MIRT681135	hsa-miR-98-5p	HITS-CLIP	23706177
MIRT681134	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681133	hsa-miR-6086	HITS-CLIP	23706177
MIRT681132	hsa-miR-6499-3p	HITS-CLIP	23706177
MIRT681131	hsa-miR-661	HITS-CLIP	23706177
MIRT681130	hsa-miR-7106-5p	HITS-CLIP	23706177
MIRT681129	hsa-miR-149-3p	HITS-CLIP	23706177
MIRT681128	hsa-miR-4728-5p	HITS-CLIP	23706177
MIRT681127	hsa-miR-6785-5p	HITS-CLIP	23706177
MIRT681126	hsa-miR-6883-5p	HITS-CLIP	23706177
MIRT681125	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT681124	hsa-miR-4451	HITS-CLIP	23706177
MIRT681123	hsa-miR-455-3p	HITS-CLIP	23706177
MIRT681122	hsa-miR-1273h-5p	HITS-CLIP	23706177
MIRT681121	hsa-miR-30b-3p	HITS-CLIP	23706177
MIRT681120	hsa-miR-3689a-3p	HITS-CLIP	23706177
MIRT681119	hsa-miR-3689b-3p	HITS-CLIP	23706177
MIRT681118	hsa-miR-3689c	HITS-CLIP	23706177
MIRT681117	hsa-miR-6779-5p	HITS-CLIP	23706177
MIRT681116	hsa-miR-6780a-5p	HITS-CLIP	23706177
MIRT681115	hsa-miR-6516-5p	HITS-CLIP	23706177
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT646142	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT646141	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT646140	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT619408	hsa-miR-4438	HITS-CLIP	23824327
MIRT619407	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT619406	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT619405	hsa-miR-4763-5p	HITS-CLIP	23824327
MIRT619404	hsa-miR-6720-3p	HITS-CLIP	23824327
MIRT619403	hsa-miR-566	HITS-CLIP	23824327
MIRT619402	hsa-miR-5095	HITS-CLIP	23824327
MIRT619401	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT619400	hsa-miR-4715-3p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT684476	hsa-miR-7153-3p	HITS-CLIP	23313552
MIRT684475	hsa-miR-589-3p	HITS-CLIP	23313552
MIRT684474	hsa-miR-490-5p	HITS-CLIP	23313552
MIRT684473	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT684472	hsa-miR-6801-5p	HITS-CLIP	23313552
MIRT684471	hsa-miR-6073	HITS-CLIP	23313552
MIRT684470	hsa-miR-142-3p	HITS-CLIP	23313552
MIRT684469	hsa-miR-134-5p	HITS-CLIP	23313552
MIRT684468	hsa-miR-3118	HITS-CLIP	23313552
MIRT684467	hsa-miR-1261	HITS-CLIP	23313552
MIRT681153	hsa-miR-3927-3p	HITS-CLIP	23706177
MIRT681152	hsa-miR-6831-5p	HITS-CLIP	23706177
MIRT681151	hsa-miR-181d-3p	HITS-CLIP	23706177
MIRT681150	hsa-miR-1203	HITS-CLIP	23706177
MIRT681149	hsa-miR-3192-5p	HITS-CLIP	23706177
MIRT681148	hsa-miR-5186	HITS-CLIP	23706177
MIRT681147	hsa-miR-3160-3p	HITS-CLIP	23706177
MIRT681146	hsa-miR-558	HITS-CLIP	23706177
MIRT681145	hsa-miR-4487	HITS-CLIP	23706177
MIRT681144	hsa-let-7a-5p	HITS-CLIP	23706177
MIRT032348	hsa-let-7b-5p	HITS-CLIP	23706177
MIRT681143	hsa-let-7c-5p	HITS-CLIP	23706177
MIRT681142	hsa-let-7d-5p	HITS-CLIP	23706177
MIRT681141	hsa-let-7e-5p	HITS-CLIP	23706177
MIRT681140	hsa-let-7f-5p	HITS-CLIP	23706177
MIRT681139	hsa-let-7g-5p	HITS-CLIP	23706177
MIRT681138	hsa-let-7i-5p	HITS-CLIP	23706177
MIRT681137	hsa-miR-4458	HITS-CLIP	23706177
MIRT681136	hsa-miR-4500	HITS-CLIP	23706177
MIRT681135	hsa-miR-98-5p	HITS-CLIP	23706177
MIRT681134	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681133	hsa-miR-6086	HITS-CLIP	23706177
MIRT681132	hsa-miR-6499-3p	HITS-CLIP	23706177
MIRT681131	hsa-miR-661	HITS-CLIP	23706177
MIRT681130	hsa-miR-7106-5p	HITS-CLIP	23706177
MIRT681129	hsa-miR-149-3p	HITS-CLIP	23706177
MIRT681128	hsa-miR-4728-5p	HITS-CLIP	23706177
MIRT681127	hsa-miR-6785-5p	HITS-CLIP	23706177
MIRT681126	hsa-miR-6883-5p	HITS-CLIP	23706177
MIRT681125	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT681124	hsa-miR-4451	HITS-CLIP	23706177
MIRT681123	hsa-miR-455-3p	HITS-CLIP	23706177
MIRT681122	hsa-miR-1273h-5p	HITS-CLIP	23706177
MIRT681121	hsa-miR-30b-3p	HITS-CLIP	23706177
MIRT681120	hsa-miR-3689a-3p	HITS-CLIP	23706177
MIRT681119	hsa-miR-3689b-3p	HITS-CLIP	23706177
MIRT681118	hsa-miR-3689c	HITS-CLIP	23706177
MIRT681117	hsa-miR-6779-5p	HITS-CLIP	23706177
MIRT681116	hsa-miR-6780a-5p	HITS-CLIP	23706177
MIRT681115	hsa-miR-6516-5p	HITS-CLIP	23706177
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT646142	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT646141	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT646140	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT619408	hsa-miR-4438	HITS-CLIP	23824327
MIRT619407	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT619406	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT619405	hsa-miR-4763-5p	HITS-CLIP	23824327
MIRT619404	hsa-miR-6720-3p	HITS-CLIP	23824327
MIRT619403	hsa-miR-566	HITS-CLIP	23824327
MIRT619402	hsa-miR-5095	HITS-CLIP	23824327
MIRT619401	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT619400	hsa-miR-4715-3p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT614035	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT614034	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT614033	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT614032	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT614031	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT614030	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT614029	hsa-miR-4682	HITS-CLIP	23824327
MIRT614028	hsa-miR-4303	HITS-CLIP	23824327
MIRT614027	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT1068219	hsa-miR-323-3p	CLIP-seq
MIRT1068220	hsa-miR-3646	CLIP-seq
MIRT1068221	hsa-miR-520d-5p	CLIP-seq
MIRT1068222	hsa-miR-524-5p	CLIP-seq
MIRT1068223	hsa-miR-548c-3p	CLIP-seq
MIRT1068224	hsa-miR-1307	CLIP-seq
MIRT1068225	hsa-miR-139-5p	CLIP-seq
MIRT1068226	hsa-miR-203	CLIP-seq
MIRT1068227	hsa-miR-2116	CLIP-seq
MIRT1068228	hsa-miR-3135b	CLIP-seq
MIRT1068229	hsa-miR-3652	CLIP-seq
MIRT1068230	hsa-miR-3659	CLIP-seq
MIRT1068231	hsa-miR-3978	CLIP-seq
MIRT1068232	hsa-miR-412	CLIP-seq
MIRT1068233	hsa-miR-4255	CLIP-seq
MIRT1068234	hsa-miR-4261	CLIP-seq
MIRT1068235	hsa-miR-4430	CLIP-seq
MIRT1068236	hsa-miR-4638-5p	CLIP-seq
MIRT1068237	hsa-miR-4658	CLIP-seq
MIRT1068238	hsa-miR-4677-5p	CLIP-seq
MIRT1068239	hsa-miR-4742-3p	CLIP-seq
MIRT1068240	hsa-miR-510	CLIP-seq
MIRT1068241	hsa-miR-574-5p	CLIP-seq
MIRT1068242	hsa-miR-654-3p	CLIP-seq
MIRT1068243	hsa-miR-1184	CLIP-seq
MIRT1068244	hsa-miR-1205	CLIP-seq
MIRT1068245	hsa-miR-1298	CLIP-seq
MIRT1068246	hsa-miR-148a	CLIP-seq
MIRT1068247	hsa-miR-148b	CLIP-seq
MIRT1068248	hsa-miR-152	CLIP-seq
MIRT1068249	hsa-miR-3158-5p	CLIP-seq
MIRT1068250	hsa-miR-4318	CLIP-seq
MIRT1068251	hsa-miR-4639-5p	CLIP-seq
MIRT1068252	hsa-miR-4693-3p	CLIP-seq
MIRT1068253	hsa-miR-4693-5p	CLIP-seq
MIRT1068254	hsa-miR-664	CLIP-seq
MIRT1068255	hsa-miR-892a	CLIP-seq
MIRT1068224	hsa-miR-1307	CLIP-seq
MIRT2016620	hsa-miR-150	CLIP-seq
MIRT1068228	hsa-miR-3135b	CLIP-seq
MIRT1068229	hsa-miR-3652	CLIP-seq
MIRT1068235	hsa-miR-4430	CLIP-seq
MIRT1068236	hsa-miR-4638-5p	CLIP-seq
MIRT2016621	hsa-miR-562	CLIP-seq
MIRT2248770	hsa-miR-1228	CLIP-seq
MIRT2248771	hsa-miR-1281	CLIP-seq
MIRT1068224	hsa-miR-1307	CLIP-seq
MIRT2016620	hsa-miR-150	CLIP-seq
MIRT2248772	hsa-miR-1915	CLIP-seq
MIRT2248773	hsa-miR-2276	CLIP-seq
MIRT1068228	hsa-miR-3135b	CLIP-seq
MIRT1068229	hsa-miR-3652	CLIP-seq
MIRT2248774	hsa-miR-377	CLIP-seq
MIRT2248775	hsa-miR-4284	CLIP-seq
MIRT1068235	hsa-miR-4430	CLIP-seq
MIRT1068236	hsa-miR-4638-5p	CLIP-seq
MIRT2248776	hsa-miR-4726-3p	CLIP-seq
MIRT2552382	hsa-miR-129-5p	CLIP-seq
MIRT2552383	hsa-miR-3149	CLIP-seq
MIRT2552384	hsa-miR-3591-5p	CLIP-seq
MIRT2552385	hsa-miR-3681	CLIP-seq
MIRT2552386	hsa-miR-4460	CLIP-seq
MIRT2552387	hsa-miR-4727-3p	CLIP-seq
MIRT2552388	hsa-miR-4735-5p	CLIP-seq
MIRT2552389	hsa-miR-4775	CLIP-seq
MIRT2552390	hsa-miR-590-3p	CLIP-seq
MIRT2552382	hsa-miR-129-5p	CLIP-seq
MIRT2552388	hsa-miR-4735-5p	CLIP-seq
MIRT2552389	hsa-miR-4775	CLIP-seq
MIRT2552390	hsa-miR-590-3p	CLIP-seq

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000077	Process	DNA damage checkpoint signaling	IMP	21659603
GO:0005515	Function	Protein binding	IPI	16239144, 21659603, 25910212
GO:0005634	Component	Nucleus	IDA	29471365, 39032490
GO:0005634	Component	Nucleus	IDA	23904267
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	32647223
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IDA	21659603
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IDA	23904267, 29471365
GO:0005737	Component	Cytoplasm	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0016180	Process	SnRNA processing	IDA	16239144
GO:0016180	Process	SnRNA processing	IEA
GO:0016180	Process	SnRNA processing	NAS	16239144
GO:0016604	Component	Nuclear body	IDA
GO:0032039	Component	Integrator complex	IBA
GO:0032039	Component	Integrator complex	IDA	16239144, 29471365, 36920904, 39032490
GO:0032039	Component	Integrator complex	IEA
GO:0032039	Component	Integrator complex	NAS	33548203
GO:0034243	Process	Regulation of transcription elongation by RNA polymerase II	NAS	32697989
GO:0034472	Process	SnRNA 3'-end processing	IBA
GO:0071479	Process	Cellular response to ionizing radiation	IDA	21659603
GO:0160232	Component	INTAC complex	IDA	33243860, 34004147, 34762484, 36869814, 38570683
GO:0160240	Process	RNA polymerase II transcription initiation surveillance	IDA	33243860, 34004147, 38570683

MIM	HGNC	e!Ensembl
611350	24484	ENSG00000143493

Q9NVH2

Protein name

Integrator complex subunit 7 (Int7)

Protein function

Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:33243860, PubMed:38570683). The integrator complex provides a quality checkpoin

PDB

7CUN , 7PKS , 7YCX , 8RBX , 8RBZ , 8RC4 , 8YJB

Family and domains

Sequence

MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPIL
INSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARA
ITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKI
SEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTL
LAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECAL
QTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIA
AHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLA
KGRPHLSQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGR
SATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHD
MAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKG
IASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGND
LQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEAL
ILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNA
IIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSK
PGLFRKIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILG
THNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYT
RF

Sequence length

962

Interactions

View interactions

	Reactome
			RNA polymerase II transcribes snRNA genes

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GOUT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTS7-related disorder	Uncertain significance; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Bipolar Disorder	Bipolar Disorder	GWASCAT_DG	22365631		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	GWASDB_DG	22365631		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	31243108		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	23692281		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	31243108		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	31243108	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

INTS7 (integrator complex subunit 7)