Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	25841
Gene name	Ankyrin repeat and BTB domain containing 2
Gene symbol	ABTB2
Synonyms (NCBI Gene)	ABTB2ABTBD22CCA3
Chromosome	11
Chromosome location	11p13

154

Show/Hide all (154)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016827	hsa-miR-335-5p	Microarray	18185580
MIRT044253	hsa-miR-106b-5p	CLASH	23622248
MIRT761145	hsa-miR-101	CLIP-seq
MIRT761146	hsa-miR-1207-5p	CLIP-seq
MIRT761147	hsa-miR-1284	CLIP-seq
MIRT761148	hsa-miR-144	CLIP-seq
MIRT761149	hsa-miR-181a	CLIP-seq
MIRT761150	hsa-miR-181b	CLIP-seq
MIRT761151	hsa-miR-181c	CLIP-seq
MIRT761152	hsa-miR-181d	CLIP-seq
MIRT761153	hsa-miR-1909	CLIP-seq
MIRT761154	hsa-miR-320e	CLIP-seq
MIRT761155	hsa-miR-4262	CLIP-seq
MIRT761156	hsa-miR-4440	CLIP-seq
MIRT761157	hsa-miR-4504	CLIP-seq
MIRT761158	hsa-miR-4698	CLIP-seq
MIRT761159	hsa-miR-4736	CLIP-seq
MIRT761160	hsa-miR-4763-3p	CLIP-seq
MIRT761161	hsa-miR-548a-5p	CLIP-seq
MIRT761162	hsa-miR-548ab	CLIP-seq
MIRT761163	hsa-miR-548ak	CLIP-seq
MIRT761164	hsa-miR-548b-5p	CLIP-seq
MIRT761165	hsa-miR-548c-5p	CLIP-seq
MIRT761166	hsa-miR-548d-5p	CLIP-seq
MIRT761167	hsa-miR-548h	CLIP-seq
MIRT761168	hsa-miR-548i	CLIP-seq
MIRT761169	hsa-miR-548j	CLIP-seq
MIRT761170	hsa-miR-548k	CLIP-seq
MIRT761171	hsa-miR-548l	CLIP-seq
MIRT761172	hsa-miR-548w	CLIP-seq
MIRT761173	hsa-miR-548y	CLIP-seq
MIRT761174	hsa-miR-549	CLIP-seq
MIRT761175	hsa-miR-559	CLIP-seq
MIRT761176	hsa-miR-582-5p	CLIP-seq
MIRT761177	hsa-miR-586	CLIP-seq
MIRT761178	hsa-miR-615-5p	CLIP-seq
MIRT761179	hsa-miR-646	CLIP-seq
MIRT1924451	hsa-miR-1205	CLIP-seq
MIRT761147	hsa-miR-1284	CLIP-seq
MIRT1924452	hsa-miR-1286	CLIP-seq
MIRT1924453	hsa-miR-1324	CLIP-seq
MIRT761149	hsa-miR-181a	CLIP-seq
MIRT761150	hsa-miR-181b	CLIP-seq
MIRT761151	hsa-miR-181c	CLIP-seq
MIRT761152	hsa-miR-181d	CLIP-seq
MIRT1924454	hsa-miR-1912	CLIP-seq
MIRT1924455	hsa-miR-3065-3p	CLIP-seq
MIRT1924456	hsa-miR-3120-3p	CLIP-seq
MIRT1924457	hsa-miR-3163	CLIP-seq
MIRT1924458	hsa-miR-3175	CLIP-seq
MIRT1924459	hsa-miR-338-5p	CLIP-seq
MIRT1924460	hsa-miR-365	CLIP-seq
MIRT1924461	hsa-miR-3661	CLIP-seq
MIRT1924462	hsa-miR-3942-5p	CLIP-seq
MIRT761155	hsa-miR-4262	CLIP-seq
MIRT1924463	hsa-miR-4459	CLIP-seq
MIRT1924464	hsa-miR-4488	CLIP-seq
MIRT1924465	hsa-miR-4494	CLIP-seq
MIRT761157	hsa-miR-4504	CLIP-seq
MIRT1924466	hsa-miR-4666-3p	CLIP-seq
MIRT1924467	hsa-miR-4697-5p	CLIP-seq
MIRT761158	hsa-miR-4698	CLIP-seq
MIRT1924468	hsa-miR-4703-5p	CLIP-seq
MIRT1924469	hsa-miR-4722-5p	CLIP-seq
MIRT1924470	hsa-miR-4757-5p	CLIP-seq
MIRT1924471	hsa-miR-4779	CLIP-seq
MIRT1924472	hsa-miR-485-3p	CLIP-seq
MIRT1924473	hsa-miR-486-5p	CLIP-seq
MIRT1924474	hsa-miR-487a	CLIP-seq
MIRT761161	hsa-miR-548a-5p	CLIP-seq
MIRT761162	hsa-miR-548ab	CLIP-seq
MIRT761163	hsa-miR-548ak	CLIP-seq
MIRT761164	hsa-miR-548b-5p	CLIP-seq
MIRT761165	hsa-miR-548c-5p	CLIP-seq
MIRT761166	hsa-miR-548d-5p	CLIP-seq
MIRT761167	hsa-miR-548h	CLIP-seq
MIRT761168	hsa-miR-548i	CLIP-seq
MIRT761169	hsa-miR-548j	CLIP-seq
MIRT761170	hsa-miR-548k	CLIP-seq
MIRT761171	hsa-miR-548l	CLIP-seq
MIRT761172	hsa-miR-548w	CLIP-seq
MIRT761173	hsa-miR-548y	CLIP-seq
MIRT761174	hsa-miR-549	CLIP-seq
MIRT761175	hsa-miR-559	CLIP-seq
MIRT761176	hsa-miR-582-5p	CLIP-seq
MIRT761177	hsa-miR-586	CLIP-seq
MIRT1924475	hsa-miR-628-5p	CLIP-seq
MIRT1924476	hsa-miR-631	CLIP-seq
MIRT1924477	hsa-miR-637	CLIP-seq
MIRT761179	hsa-miR-646	CLIP-seq
MIRT1924478	hsa-miR-922	CLIP-seq
MIRT1924479	hsa-miR-942	CLIP-seq
MIRT761146	hsa-miR-1207-5p	CLIP-seq
MIRT761153	hsa-miR-1909	CLIP-seq
MIRT2165665	hsa-miR-2110	CLIP-seq
MIRT2165666	hsa-miR-2964a-3p	CLIP-seq
MIRT2165667	hsa-miR-3119	CLIP-seq
MIRT1924456	hsa-miR-3120-3p	CLIP-seq
MIRT2165668	hsa-miR-3127-5p	CLIP-seq
MIRT1924457	hsa-miR-3163	CLIP-seq
MIRT2165669	hsa-miR-3180-5p	CLIP-seq
MIRT761154	hsa-miR-320e	CLIP-seq
MIRT2165670	hsa-miR-331-3p	CLIP-seq
MIRT1924459	hsa-miR-338-5p	CLIP-seq
MIRT1924460	hsa-miR-365	CLIP-seq
MIRT1924461	hsa-miR-3661	CLIP-seq
MIRT1924462	hsa-miR-3942-5p	CLIP-seq
MIRT2165671	hsa-miR-4271	CLIP-seq
MIRT2165672	hsa-miR-4274	CLIP-seq
MIRT2165673	hsa-miR-4290	CLIP-seq
MIRT2165674	hsa-miR-4292	CLIP-seq
MIRT761156	hsa-miR-4440	CLIP-seq
MIRT2165675	hsa-miR-4471	CLIP-seq
MIRT1924464	hsa-miR-4488	CLIP-seq
MIRT1924466	hsa-miR-4666-3p	CLIP-seq
MIRT2165676	hsa-miR-4667-5p	CLIP-seq
MIRT1924467	hsa-miR-4697-5p	CLIP-seq
MIRT2165677	hsa-miR-4700-5p	CLIP-seq
MIRT1924468	hsa-miR-4703-5p	CLIP-seq
MIRT2165678	hsa-miR-4725-3p	CLIP-seq
MIRT2165679	hsa-miR-4731-5p	CLIP-seq
MIRT761159	hsa-miR-4736	CLIP-seq
MIRT761160	hsa-miR-4763-3p	CLIP-seq
MIRT1924472	hsa-miR-485-3p	CLIP-seq
MIRT1924474	hsa-miR-487a	CLIP-seq
MIRT2165680	hsa-miR-520a-5p	CLIP-seq
MIRT2165681	hsa-miR-525-5p	CLIP-seq
MIRT761177	hsa-miR-586	CLIP-seq
MIRT761178	hsa-miR-615-5p	CLIP-seq
MIRT1924476	hsa-miR-631	CLIP-seq
MIRT1924477	hsa-miR-637	CLIP-seq
MIRT2442992	hsa-miR-1273f	CLIP-seq
MIRT2442993	hsa-miR-143	CLIP-seq
MIRT2442994	hsa-miR-3150a-3p	CLIP-seq
MIRT1924458	hsa-miR-3175	CLIP-seq
MIRT2442995	hsa-miR-4708-5p	CLIP-seq
MIRT2442996	hsa-miR-4770	CLIP-seq
MIRT1924471	hsa-miR-4779	CLIP-seq
MIRT2442997	hsa-miR-765	CLIP-seq
MIRT2442998	hsa-miR-939	CLIP-seq
MIRT761147	hsa-miR-1284	CLIP-seq
MIRT761149	hsa-miR-181a	CLIP-seq
MIRT761150	hsa-miR-181b	CLIP-seq
MIRT761151	hsa-miR-181c	CLIP-seq
MIRT761152	hsa-miR-181d	CLIP-seq
MIRT761155	hsa-miR-4262	CLIP-seq
MIRT761177	hsa-miR-586	CLIP-seq
MIRT761147	hsa-miR-1284	CLIP-seq
MIRT761149	hsa-miR-181a	CLIP-seq
MIRT761150	hsa-miR-181b	CLIP-seq
MIRT761151	hsa-miR-181c	CLIP-seq
MIRT761152	hsa-miR-181d	CLIP-seq
MIRT761155	hsa-miR-4262	CLIP-seq
MIRT761177	hsa-miR-586	CLIP-seq

Show/Hide all (3)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	36931259
GO:0046982	Function	Protein heterodimerization activity	IEA
GO:0097237	Process	Cellular response to toxic substance	IEA

MIM	HGNC	e!Ensembl
621014	23842	ENSG00000166016

Q8N961

Protein name

Ankyrin repeat and BTB/POZ domain-containing protein 2

Protein function

May be involved in the initiation of hepatocyte growth.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12796	Ank_2	492 → 598	Ankyrin repeats (3 copies)	Repeat
PF13637	Ank_4	522 → 588		Repeat
PF00651	BTB	836 → 947	BTB/POZ domain	Domain

Sequence

MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGS
MNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQF
SAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVK
ALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVE
EIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLP
AYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPL
CPGASPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLL
PPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPEHCFSSFRRLDAR
AATEKFNQDLGFRMLNCGRTDLINQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQM
LIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVN
GGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEAHGMGSSLHEDMNCFSHSAAH
GHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDASSQGSGSEGPVRLSRTRTKALQEA
MYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLRDFSSIREEEYN
EELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPEIRKTLPARLDPHFLN
NKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQM
MMQYLYYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAK
IHNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQNTLAERVHSVY
ITSRV

Sequence length

1025

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BRAIN INFARCTION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CEREBRAL AMYLOID ANGIOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LEWY BODY DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OCULAR HYPOTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★★★★★ ★☆☆☆☆ Found in Text Mining only

ABTB2 (ankyrin repeat and BTB domain containing 2)