SUN2 (Sad1 and UNC84 domain containing 2)

Gene

• Entrez ID: 25777
• Gene name: Sad1 and UNC84 domain containing 2
• Gene symbol: SUN2
• Synonyms (NCBI Gene): UNC84B, rab5IP
• Chromosome: 22
• Chromosome location: 22q13.1
• Summary: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a `bridge` across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KAS

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020123	hsa-miR-130b-3p	Sequencing	20371350
MIRT027033	hsa-miR-103a-3p	Sequencing	20371350
MIRT050037	hsa-miR-27a-3p	CLASH	23622248
MIRT047952	hsa-miR-30c-5p	CLASH	23622248
MIRT046749	hsa-miR-222-3p	CLASH	23622248
MIRT036434	hsa-miR-1226-3p	CLASH	23622248
MIRT652978	hsa-miR-335-5p	HITS-CLIP	23824327
MIRT652977	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT652976	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT652975	hsa-miR-665	HITS-CLIP	23824327
MIRT652974	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT652973	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT652972	hsa-miR-4286	HITS-CLIP	23824327
MIRT652971	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT652970	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT652969	hsa-miR-5581-3p	HITS-CLIP	23824327
MIRT553904	hsa-miR-542-3p	PAR-CLIP	20371350
MIRT553903	hsa-miR-758-3p	PAR-CLIP	20371350
MIRT553902	hsa-miR-107	PAR-CLIP	20371350
MIRT027033	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT553901	hsa-miR-548b-3p	PAR-CLIP	20371350
MIRT553900	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT020123	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT553899	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT553898	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT553896	hsa-miR-3666	PAR-CLIP	20371350
MIRT553897	hsa-miR-4295	PAR-CLIP	20371350
MIRT553895	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT553893	hsa-miR-4310	PAR-CLIP	20371350
MIRT553894	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT553891	hsa-miR-4504	PAR-CLIP	20371350
MIRT553890	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT553889	hsa-miR-4671-3p	PAR-CLIP	20371350
MIRT553888	hsa-miR-6808-3p	PAR-CLIP	20371350
MIRT553887	hsa-miR-3660	PAR-CLIP	20371350
MIRT553904	hsa-miR-542-3p	PAR-CLIP	21572407
MIRT553903	hsa-miR-758-3p	PAR-CLIP	21572407
MIRT553902	hsa-miR-107	PAR-CLIP	21572407
MIRT027033	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553901	hsa-miR-548b-3p	PAR-CLIP	21572407
MIRT553900	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT020123	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT553899	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT553898	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT553896	hsa-miR-3666	PAR-CLIP	21572407
MIRT553897	hsa-miR-4295	PAR-CLIP	21572407
MIRT553895	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT553893	hsa-miR-4310	PAR-CLIP	21572407
MIRT553894	hsa-miR-7157-5p	PAR-CLIP	21572407
MIRT553892	hsa-miR-4768-3p	PAR-CLIP	21572407
MIRT553891	hsa-miR-4504	PAR-CLIP	21572407
MIRT553890	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT553889	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT553888	hsa-miR-6808-3p	PAR-CLIP	21572407
MIRT553887	hsa-miR-3660	PAR-CLIP	21572407
MIRT652978	hsa-miR-335-5p	HITS-CLIP	23824327
MIRT652977	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT652976	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT652975	hsa-miR-665	HITS-CLIP	23824327
MIRT652974	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT652973	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT652972	hsa-miR-4286	HITS-CLIP	23824327
MIRT652971	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT652970	hsa-miR-7106-3p	HITS-CLIP	23824327
MIRT652969	hsa-miR-5581-3p	HITS-CLIP	23824327
MIRT553904	hsa-miR-542-3p	PAR-CLIP	20371350
MIRT553903	hsa-miR-758-3p	PAR-CLIP	20371350
MIRT553902	hsa-miR-107	PAR-CLIP	20371350
MIRT027033	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT553901	hsa-miR-548b-3p	PAR-CLIP	20371350
MIRT553900	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT020123	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT553899	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT553898	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT553896	hsa-miR-3666	PAR-CLIP	20371350
MIRT553897	hsa-miR-4295	PAR-CLIP	20371350
MIRT553895	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT553893	hsa-miR-4310	PAR-CLIP	20371350
MIRT553894	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT553891	hsa-miR-4504	PAR-CLIP	20371350
MIRT553890	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT553889	hsa-miR-4671-3p	PAR-CLIP	20371350
MIRT553888	hsa-miR-6808-3p	PAR-CLIP	20371350
MIRT553887	hsa-miR-3660	PAR-CLIP	20371350
MIRT553904	hsa-miR-542-3p	PAR-CLIP	21572407
MIRT553903	hsa-miR-758-3p	PAR-CLIP	21572407
MIRT553902	hsa-miR-107	PAR-CLIP	21572407
MIRT027033	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT553901	hsa-miR-548b-3p	PAR-CLIP	21572407
MIRT553900	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT020123	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT553899	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT553898	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT553896	hsa-miR-3666	PAR-CLIP	21572407
MIRT553897	hsa-miR-4295	PAR-CLIP	21572407
MIRT553895	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT553893	hsa-miR-4310	PAR-CLIP	21572407
MIRT553894	hsa-miR-7157-5p	PAR-CLIP	21572407
MIRT553892	hsa-miR-4768-3p	PAR-CLIP	21572407
MIRT553891	hsa-miR-4504	PAR-CLIP	21572407
MIRT553890	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT553889	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT553888	hsa-miR-6808-3p	PAR-CLIP	21572407
MIRT553887	hsa-miR-3660	PAR-CLIP	21572407
MIRT1403446	hsa-miR-1252	CLIP-seq
MIRT1403447	hsa-miR-1825	CLIP-seq
MIRT1403448	hsa-miR-3154	CLIP-seq
MIRT1403449	hsa-miR-3185	CLIP-seq
MIRT1403450	hsa-miR-3189-5p	CLIP-seq
MIRT1403451	hsa-miR-371b-3p	CLIP-seq
MIRT1403452	hsa-miR-4293	CLIP-seq
MIRT1403453	hsa-miR-4300	CLIP-seq
MIRT1403454	hsa-miR-4533	CLIP-seq
MIRT1403455	hsa-miR-4747-5p	CLIP-seq
MIRT1403456	hsa-miR-4749-3p	CLIP-seq
MIRT1403457	hsa-miR-4758-3p	CLIP-seq
MIRT1403458	hsa-miR-486-3p	CLIP-seq
MIRT1403459	hsa-miR-499-3p	CLIP-seq
MIRT1403460	hsa-miR-499a-3p	CLIP-seq
MIRT1403461	hsa-miR-558	CLIP-seq
MIRT1403462	hsa-miR-920	CLIP-seq
MIRT1403463	hsa-miR-10a	CLIP-seq
MIRT1403464	hsa-miR-10b	CLIP-seq
MIRT1403465	hsa-miR-1248	CLIP-seq
MIRT1403466	hsa-miR-1913	CLIP-seq
MIRT1403467	hsa-miR-3127-3p	CLIP-seq
MIRT1403450	hsa-miR-3189-5p	CLIP-seq
MIRT1403468	hsa-miR-3190	CLIP-seq
MIRT1403469	hsa-miR-3192	CLIP-seq
MIRT1403470	hsa-miR-324-3p	CLIP-seq
MIRT1403471	hsa-miR-3919	CLIP-seq
MIRT1403472	hsa-miR-3925-5p	CLIP-seq
MIRT1403473	hsa-miR-3978	CLIP-seq
MIRT1403474	hsa-miR-4292	CLIP-seq
MIRT1403475	hsa-miR-4491	CLIP-seq
MIRT1403476	hsa-miR-4493	CLIP-seq
MIRT1403477	hsa-miR-4657	CLIP-seq
MIRT1403478	hsa-miR-4707-3p	CLIP-seq
MIRT1403456	hsa-miR-4749-3p	CLIP-seq
MIRT1403457	hsa-miR-4758-3p	CLIP-seq
MIRT1403479	hsa-miR-4763-5p	CLIP-seq
MIRT1403480	hsa-miR-495	CLIP-seq
MIRT1403447	hsa-miR-1825	CLIP-seq
MIRT1403451	hsa-miR-371b-3p	CLIP-seq
MIRT2342900	hsa-miR-1291	CLIP-seq
MIRT1403447	hsa-miR-1825	CLIP-seq
MIRT2342901	hsa-miR-2467-3p	CLIP-seq
MIRT2342902	hsa-miR-296-5p	CLIP-seq
MIRT2342903	hsa-miR-3130-5p	CLIP-seq
MIRT1403450	hsa-miR-3189-5p	CLIP-seq
MIRT2342904	hsa-miR-328	CLIP-seq
MIRT2342905	hsa-miR-3664-3p	CLIP-seq
MIRT2342906	hsa-miR-370	CLIP-seq
MIRT1403451	hsa-miR-371b-3p	CLIP-seq
MIRT1403474	hsa-miR-4292	CLIP-seq
MIRT2342907	hsa-miR-4482	CLIP-seq
MIRT2342908	hsa-miR-4738-3p	CLIP-seq
MIRT1403457	hsa-miR-4758-3p	CLIP-seq
MIRT2342909	hsa-miR-496	CLIP-seq
MIRT2342910	hsa-miR-767-3p	CLIP-seq
MIRT2395436	hsa-miR-2861	CLIP-seq
MIRT2440880	hsa-miR-335	CLIP-seq
MIRT2460818	hsa-miR-1247	CLIP-seq
MIRT2342905	hsa-miR-3664-3p	CLIP-seq
MIRT2460819	hsa-miR-4433	CLIP-seq
MIRT2460820	hsa-miR-4459	CLIP-seq
MIRT2460821	hsa-miR-4725-5p	CLIP-seq
MIRT2460822	hsa-miR-504	CLIP-seq
MIRT2342910	hsa-miR-767-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000781	Component	Chromosome, telomeric region	IEA
GO:0000794	Component	Condensed nuclear chromosome	IEA
GO:0005515	Function	Protein binding	IPI	18396275, 19933576, 20551905, 21391237, 21988832, 22555292, 22632968, 25416956, 26496610, 28514442, 30833792, 31980649, 32353859, 33058875, 33060197, 33393904, 33961781, 35311970, 36217030
GO:0005521	Function	Lamin binding	IDA	19933576
GO:0005634	Component	Nucleus	IEA
GO:0005635	Component	Nuclear envelope	IBA
GO:0005635	Component	Nuclear envelope	IDA	21610090
GO:0005635	Component	Nuclear envelope	IDA	16380439, 19933576
GO:0005635	Component	Nuclear envelope	IEA
GO:0005635	Component	Nuclear envelope	TAS	10375507
GO:0005637	Component	Nuclear inner membrane	IEA
GO:0005768	Component	Endosome	IEA
GO:0007052	Process	Mitotic spindle organization	TAS	10375507
GO:0007097	Process	Nuclear migration	TAS	10508607
GO:0008017	Function	Microtubule binding	TAS	10375507
GO:0010008	Component	Endosome membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0021817	Process	Nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	IEA
GO:0030335	Process	Positive regulation of cell migration	IEA
GO:0030335	Process	Positive regulation of cell migration	ISS
GO:0031022	Process	Nuclear migration along microfilament	IEA
GO:0031022	Process	Nuclear migration along microfilament	ISS
GO:0031965	Component	Nuclear membrane	IDA
GO:0031965	Component	Nuclear membrane	IEA
GO:0034993	Component	Meiotic nuclear membrane microtubule tethering complex	IBA
GO:0034993	Component	Meiotic nuclear membrane microtubule tethering complex	IDA	18396275
GO:0034993	Component	Meiotic nuclear membrane microtubule tethering complex	IEA
GO:0042802	Function	Identical protein binding	IPI	22632968, 33058875
GO:0043495	Function	Protein-membrane adaptor activity	IBA
GO:0051321	Process	Meiotic cell cycle	IEA
GO:0051642	Process	Centrosome localization	IEA
GO:0051642	Process	Centrosome localization	ISS
GO:0090292	Process	Nuclear matrix anchoring at nuclear membrane	IDA	19933576
GO:0090292	Process	Nuclear matrix anchoring at nuclear membrane	IEA
GO:0140444	Function	Cytoskeleton-nuclear membrane anchor activity	IDA	18396275
GO:0140444	Function	Cytoskeleton-nuclear membrane anchor activity	IEA

Other IDs

• MIM: 613569
• HGNC: 14210
• e!Ensembl: ENSG00000100242

Protein

• UniProt ID: Q9UH99
• Protein name: SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2)
• Protein function: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role
• PDB: 3UNP, 4DXR, 4DXS, 4DXT, 4FI9, 6WMD, 6WME, 6WMF, 6WMG
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF18580	HTH_SUN2	481 → 538	SUN2 helix-turn-helix domain	Domain
  PF07738	Sad1_UNC	581 → 715	Sad1 / UNC-like C-terminal	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Highly expressed in heart, lung and muscle. Weakly expressed in fetal heart. Slightly overexpressed in some heart tissues form patients with congenital heart defects. {ECO:0000269|PubMed:10818110, ECO:0000269|PubMed:1
• Sequence:

  MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLG
  PSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVG
  RKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLL
  YWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQT
  FHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQK
  EAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELS
  ALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAG
  LQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREE
  MQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYS
  EDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGN
  CWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGT
  LLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH

• Sequence length: 717

Pathways

KEGG:

Cytoskeleton in muscle cells

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Likely benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIVERTICULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Emery-Dreifuss muscular dystrophy	Uncertain significance; Likely benign; Benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adult Medulloblastoma	Medulloblastoma	BEFREE	24832085		★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	GWASDB_DG	23587638		★☆☆☆☆ Found in Text Mining only
Atypical Teratoid Rhabdoid Tumor	Teratoid Rhabdoid Tumor	BEFREE	24832085		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	29163775, 29981820, 30675193		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	26175118	Inhibit	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	26658802, 29163775, 30675193		★☆☆☆☆ Found in Text Mining only
Childhood Medulloblastoma	Medulloblastoma	BEFREE	24832085		★☆☆☆☆ Found in Text Mining only
Embryonal Neoplasm	Embryonal Neoplasm	BEFREE	24832085		★☆☆☆☆ Found in Text Mining only
Fibrosis, Liver	Liver Fibrosis	BEFREE	30282980		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	26658802	Inhibit	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	29163775, 29981820, 30675193		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	26658802, 29163775, 30675193		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	29163775, 31562322		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	30675193		★☆☆☆☆ Found in Text Mining only
Mandibuloacral dysostosis	Mandibuloacral Dysostosis	BEFREE	22706480		★☆☆☆☆ Found in Text Mining only
Mandibuloacral dysplasia with type A lipodystrophy	Mandibuloacral dysplasia	Pubtator	22706480	Associate	★☆☆☆☆ Found in Text Mining only
Medulloblastoma	Medulloblastoma	BEFREE	24832085		★☆☆☆☆ Found in Text Mining only
MIRROR MOVEMENTS 3	Mirror Movements	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy Emery Dreifuss	Emery dreifuss muscular dystrophy	Pubtator	22555292	Associate	★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy, Duchenne	Duchenne Muscular Dystrophy	BEFREE	22555292		★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy, Emery-Dreifuss	Emery-Dreifuss Muscular Dystrophy	BEFREE	22555292		★☆☆☆☆ Found in Text Mining only
Myopathy	Myopathy	BEFREE	25210889		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	24832085, 26658802		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	29163775, 31562322		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate carcinoma	Prostate cancer	GWASCAT_DG	31562322		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	31562322	Associate	★☆☆☆☆ Found in Text Mining only
SPASTIC ATAXIA, CHARLEVOIX-SAGUENAY TYPE	Spastic Ataxia	BEFREE	29891078		★☆☆☆☆ Found in Text Mining only
Tetralogy of Fallot	Tetralogy of Fallot	BEFREE	12393179		★☆☆☆☆ Found in Text Mining only