ZDHHC23 (zDHHC palmitoyltransferase 23)

Gene

• Entrez ID: 254887
• Gene name: ZDHHC palmitoyltransferase 23
• Gene symbol: ZDHHC23
• Synonyms (NCBI Gene): DHHC-23, NIDD
• Chromosome: 3
• Chromosome location: 3q13.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024437	hsa-miR-215-5p	Microarray	19074876
MIRT026927	hsa-miR-192-5p	Microarray	19074876
MIRT647380	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT647379	hsa-miR-497-3p	HITS-CLIP	23824327
MIRT647378	hsa-miR-8063	HITS-CLIP	23824327
MIRT647377	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT647376	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT647380	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT647379	hsa-miR-497-3p	HITS-CLIP	23824327
MIRT647378	hsa-miR-8063	HITS-CLIP	23824327
MIRT647377	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT647376	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT1508448	hsa-miR-103a	CLIP-seq
MIRT1508449	hsa-miR-107	CLIP-seq
MIRT1508450	hsa-miR-1185	CLIP-seq
MIRT1508451	hsa-miR-1203	CLIP-seq
MIRT1508452	hsa-miR-129-5p	CLIP-seq
MIRT1508453	hsa-miR-1298	CLIP-seq
MIRT1508454	hsa-miR-130a	CLIP-seq
MIRT1508455	hsa-miR-130b	CLIP-seq
MIRT1508456	hsa-miR-135a	CLIP-seq
MIRT1508457	hsa-miR-135b	CLIP-seq
MIRT1508458	hsa-miR-148a	CLIP-seq
MIRT1508459	hsa-miR-148b	CLIP-seq
MIRT1508460	hsa-miR-152	CLIP-seq
MIRT1508461	hsa-miR-153	CLIP-seq
MIRT1508462	hsa-miR-154	CLIP-seq
MIRT1508463	hsa-miR-15a	CLIP-seq
MIRT1508464	hsa-miR-15b	CLIP-seq
MIRT1508465	hsa-miR-16	CLIP-seq
MIRT1508466	hsa-miR-195	CLIP-seq
MIRT1508467	hsa-miR-197	CLIP-seq
MIRT1508468	hsa-miR-19a	CLIP-seq
MIRT1508469	hsa-miR-19b	CLIP-seq
MIRT1508470	hsa-miR-2053	CLIP-seq
MIRT1508471	hsa-miR-223	CLIP-seq
MIRT1508472	hsa-miR-2276	CLIP-seq
MIRT1508473	hsa-miR-25	CLIP-seq
MIRT1508474	hsa-miR-2682	CLIP-seq
MIRT1508475	hsa-miR-299-3p	CLIP-seq
MIRT1508476	hsa-miR-300	CLIP-seq
MIRT1508477	hsa-miR-301a	CLIP-seq
MIRT1508478	hsa-miR-301b	CLIP-seq
MIRT1508479	hsa-miR-3161	CLIP-seq
MIRT1508480	hsa-miR-3163	CLIP-seq
MIRT1508481	hsa-miR-3166	CLIP-seq
MIRT1508482	hsa-miR-32	CLIP-seq
MIRT1508483	hsa-miR-3201	CLIP-seq
MIRT1508484	hsa-miR-323-3p	CLIP-seq
MIRT1508485	hsa-miR-338-5p	CLIP-seq
MIRT1508486	hsa-miR-363	CLIP-seq
MIRT1508487	hsa-miR-3653	CLIP-seq
MIRT1508488	hsa-miR-3658	CLIP-seq
MIRT1508489	hsa-miR-3666	CLIP-seq
MIRT1508490	hsa-miR-3667-5p	CLIP-seq
MIRT1508491	hsa-miR-367	CLIP-seq
MIRT1508492	hsa-miR-3674	CLIP-seq
MIRT1508493	hsa-miR-3679-5p	CLIP-seq
MIRT1508494	hsa-miR-3692	CLIP-seq
MIRT1508495	hsa-miR-381	CLIP-seq
MIRT1508496	hsa-miR-409-3p	CLIP-seq
MIRT1508497	hsa-miR-410	CLIP-seq
MIRT1508498	hsa-miR-424	CLIP-seq
MIRT1508499	hsa-miR-4277	CLIP-seq
MIRT1508500	hsa-miR-4282	CLIP-seq
MIRT1508501	hsa-miR-4295	CLIP-seq
MIRT1508502	hsa-miR-4474-3p	CLIP-seq
MIRT1508503	hsa-miR-4474-5p	CLIP-seq
MIRT1508504	hsa-miR-448	CLIP-seq
MIRT1508505	hsa-miR-4491	CLIP-seq
MIRT1508506	hsa-miR-4495	CLIP-seq
MIRT1508507	hsa-miR-449c	CLIP-seq
MIRT1508508	hsa-miR-4524	CLIP-seq
MIRT1508509	hsa-miR-454	CLIP-seq
MIRT1508510	hsa-miR-4646-3p	CLIP-seq
MIRT1508511	hsa-miR-4649-3p	CLIP-seq
MIRT1508512	hsa-miR-4657	CLIP-seq
MIRT1508513	hsa-miR-4682	CLIP-seq
MIRT1508514	hsa-miR-4696	CLIP-seq
MIRT1508515	hsa-miR-4697-3p	CLIP-seq
MIRT1508516	hsa-miR-4698	CLIP-seq
MIRT1508517	hsa-miR-4711-3p	CLIP-seq
MIRT1508518	hsa-miR-4711-5p	CLIP-seq
MIRT1508519	hsa-miR-4715-5p	CLIP-seq
MIRT1508520	hsa-miR-4716-5p	CLIP-seq
MIRT1508521	hsa-miR-4759	CLIP-seq
MIRT1508522	hsa-miR-4766-3p	CLIP-seq
MIRT1508523	hsa-miR-4772-3p	CLIP-seq
MIRT1508524	hsa-miR-4791	CLIP-seq
MIRT1508525	hsa-miR-497	CLIP-seq
MIRT1508526	hsa-miR-503	CLIP-seq
MIRT1508527	hsa-miR-513a-3p	CLIP-seq
MIRT1508528	hsa-miR-544	CLIP-seq
MIRT1508529	hsa-miR-548ac	CLIP-seq
MIRT1508530	hsa-miR-548ae	CLIP-seq
MIRT1508531	hsa-miR-548aj	CLIP-seq
MIRT1508532	hsa-miR-548am	CLIP-seq
MIRT1508533	hsa-miR-548c-3p	CLIP-seq
MIRT1508534	hsa-miR-548d-3p	CLIP-seq
MIRT1508535	hsa-miR-548p	CLIP-seq
MIRT1508536	hsa-miR-548x	CLIP-seq
MIRT1508537	hsa-miR-548z	CLIP-seq
MIRT1508538	hsa-miR-561	CLIP-seq
MIRT1508539	hsa-miR-569	CLIP-seq
MIRT1508540	hsa-miR-570	CLIP-seq
MIRT1508541	hsa-miR-571	CLIP-seq
MIRT1508542	hsa-miR-579	CLIP-seq
MIRT1508543	hsa-miR-587	CLIP-seq
MIRT1508544	hsa-miR-605	CLIP-seq
MIRT1508545	hsa-miR-607	CLIP-seq
MIRT1508546	hsa-miR-617	CLIP-seq
MIRT1508547	hsa-miR-627	CLIP-seq
MIRT1508548	hsa-miR-646	CLIP-seq
MIRT1508549	hsa-miR-656	CLIP-seq
MIRT1508550	hsa-miR-873	CLIP-seq
MIRT1508551	hsa-miR-922	CLIP-seq
MIRT1508552	hsa-miR-924	CLIP-seq
MIRT1508553	hsa-miR-92a	CLIP-seq
MIRT1508554	hsa-miR-92b	CLIP-seq
MIRT1508555	hsa-miR-935	CLIP-seq
MIRT1508556	hsa-miR-940	CLIP-seq
MIRT2153189	hsa-miR-1245b-3p	CLIP-seq
MIRT2153190	hsa-miR-128	CLIP-seq
MIRT2153191	hsa-miR-132	CLIP-seq
MIRT1508470	hsa-miR-2053	CLIP-seq
MIRT2153192	hsa-miR-208a	CLIP-seq
MIRT2153193	hsa-miR-208b	CLIP-seq
MIRT2153194	hsa-miR-212	CLIP-seq
MIRT1508471	hsa-miR-223	CLIP-seq
MIRT1508474	hsa-miR-2682	CLIP-seq
MIRT2153195	hsa-miR-3128	CLIP-seq
MIRT2153196	hsa-miR-3140-5p	CLIP-seq
MIRT2153197	hsa-miR-3190	CLIP-seq
MIRT2153198	hsa-miR-3197	CLIP-seq
MIRT2153199	hsa-miR-325	CLIP-seq
MIRT2153200	hsa-miR-34a	CLIP-seq
MIRT2153201	hsa-miR-34c-5p	CLIP-seq
MIRT2153202	hsa-miR-3617	CLIP-seq
MIRT2153203	hsa-miR-3650	CLIP-seq
MIRT2153204	hsa-miR-3677-5p	CLIP-seq
MIRT2153205	hsa-miR-3682-3p	CLIP-seq
MIRT2153206	hsa-miR-3689a-5p	CLIP-seq
MIRT2153207	hsa-miR-3689b	CLIP-seq
MIRT2153208	hsa-miR-3689e	CLIP-seq
MIRT2153209	hsa-miR-3689f	CLIP-seq
MIRT2153210	hsa-miR-369-3p	CLIP-seq
MIRT2153211	hsa-miR-374c	CLIP-seq
MIRT2153212	hsa-miR-412	CLIP-seq
MIRT1508499	hsa-miR-4277	CLIP-seq
MIRT2153213	hsa-miR-4427	CLIP-seq
MIRT2153214	hsa-miR-4435	CLIP-seq
MIRT2153215	hsa-miR-449a	CLIP-seq
MIRT2153216	hsa-miR-449b	CLIP-seq
MIRT1508507	hsa-miR-449c	CLIP-seq
MIRT2153217	hsa-miR-451	CLIP-seq
MIRT2153218	hsa-miR-455-3p	CLIP-seq
MIRT2153219	hsa-miR-4672	CLIP-seq
MIRT2153220	hsa-miR-4694-3p	CLIP-seq
MIRT2153221	hsa-miR-4699-5p	CLIP-seq
MIRT2153222	hsa-miR-4720-5p	CLIP-seq
MIRT1508522	hsa-miR-4766-3p	CLIP-seq
MIRT2153223	hsa-miR-4797-5p	CLIP-seq
MIRT2153224	hsa-miR-4799-3p	CLIP-seq
MIRT2153225	hsa-miR-499-5p	CLIP-seq
MIRT2153226	hsa-miR-511	CLIP-seq
MIRT2153227	hsa-miR-513a-5p	CLIP-seq
MIRT2153228	hsa-miR-513c	CLIP-seq
MIRT2153229	hsa-miR-514b-5p	CLIP-seq
MIRT2153230	hsa-miR-522	CLIP-seq
MIRT1508539	hsa-miR-569	CLIP-seq
MIRT1508542	hsa-miR-579	CLIP-seq
MIRT1508543	hsa-miR-587	CLIP-seq
MIRT2153231	hsa-miR-628-3p	CLIP-seq
MIRT2153232	hsa-miR-641	CLIP-seq
MIRT2153233	hsa-miR-655	CLIP-seq
MIRT2153234	hsa-miR-7	CLIP-seq
MIRT1508550	hsa-miR-873	CLIP-seq
MIRT2153235	hsa-miR-892a	CLIP-seq
MIRT1508556	hsa-miR-940	CLIP-seq
MIRT2373449	hsa-miR-105	CLIP-seq
MIRT2153189	hsa-miR-1245b-3p	CLIP-seq
MIRT2373450	hsa-miR-1246	CLIP-seq
MIRT1508453	hsa-miR-1298	CLIP-seq
MIRT2373451	hsa-miR-141	CLIP-seq
MIRT2373452	hsa-miR-200a	CLIP-seq
MIRT1508470	hsa-miR-2053	CLIP-seq
MIRT2373453	hsa-miR-2115	CLIP-seq
MIRT1508471	hsa-miR-223	CLIP-seq
MIRT2153195	hsa-miR-3128	CLIP-seq
MIRT2153196	hsa-miR-3140-5p	CLIP-seq
MIRT1508481	hsa-miR-3166	CLIP-seq
MIRT2153197	hsa-miR-3190	CLIP-seq
MIRT2153198	hsa-miR-3197	CLIP-seq
MIRT2373454	hsa-miR-3199	CLIP-seq
MIRT2153199	hsa-miR-325	CLIP-seq
MIRT2153200	hsa-miR-34a	CLIP-seq
MIRT2153201	hsa-miR-34c-5p	CLIP-seq
MIRT2153205	hsa-miR-3682-3p	CLIP-seq
MIRT2153210	hsa-miR-369-3p	CLIP-seq
MIRT2153211	hsa-miR-374c	CLIP-seq
MIRT1508499	hsa-miR-4277	CLIP-seq
MIRT1508500	hsa-miR-4282	CLIP-seq
MIRT2373455	hsa-miR-4292	CLIP-seq
MIRT2373456	hsa-miR-4308	CLIP-seq
MIRT2153213	hsa-miR-4427	CLIP-seq
MIRT2373457	hsa-miR-4477a	CLIP-seq
MIRT1508506	hsa-miR-4495	CLIP-seq
MIRT2153215	hsa-miR-449a	CLIP-seq
MIRT2153216	hsa-miR-449b	CLIP-seq
MIRT2373458	hsa-miR-4632	CLIP-seq
MIRT2153219	hsa-miR-4672	CLIP-seq
MIRT2153221	hsa-miR-4699-5p	CLIP-seq
MIRT1508518	hsa-miR-4711-5p	CLIP-seq
MIRT1508520	hsa-miR-4716-5p	CLIP-seq
MIRT2153222	hsa-miR-4720-5p	CLIP-seq
MIRT2373459	hsa-miR-4740-5p	CLIP-seq
MIRT2153223	hsa-miR-4797-5p	CLIP-seq
MIRT2153224	hsa-miR-4799-3p	CLIP-seq
MIRT2373460	hsa-miR-490-5p	CLIP-seq
MIRT1508527	hsa-miR-513a-3p	CLIP-seq
MIRT2153227	hsa-miR-513a-5p	CLIP-seq
MIRT2373461	hsa-miR-516a-3p	CLIP-seq
MIRT1508539	hsa-miR-569	CLIP-seq
MIRT1508542	hsa-miR-579	CLIP-seq
MIRT1508543	hsa-miR-587	CLIP-seq
MIRT2153231	hsa-miR-628-3p	CLIP-seq
MIRT2153233	hsa-miR-655	CLIP-seq
MIRT2373462	hsa-miR-664	CLIP-seq
MIRT2373463	hsa-miR-670	CLIP-seq
MIRT2153234	hsa-miR-7	CLIP-seq
MIRT2373464	hsa-miR-767-3p	CLIP-seq
MIRT1508550	hsa-miR-873	CLIP-seq
MIRT2153235	hsa-miR-892a	CLIP-seq
MIRT1508551	hsa-miR-922	CLIP-seq
MIRT2695626	hsa-miR-1290	CLIP-seq
MIRT2695627	hsa-miR-4659a-3p	CLIP-seq
MIRT2695628	hsa-miR-4659b-3p	CLIP-seq
MIRT2695629	hsa-miR-4778-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0006612	Process	Protein targeting to membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016409	Function	Palmitoyltransferase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016746	Function	Acyltransferase activity	IEA
GO:0018345	Process	Protein palmitoylation	IMP	22399288
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IBA
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IEA
GO:0072659	Process	Protein localization to plasma membrane	IBA
GO:0072659	Process	Protein localization to plasma membrane	IMP	22399288

Other IDs

• MIM: 617334
• HGNC: 28654
• e!Ensembl: ENSG00000184307

Protein

• UniProt ID: Q8IYP9
• Protein name: Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23)
• Protein function: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (Probable). Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localizatio
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01529	DHHC	254 → 388	DHHC palmitoyltransferase	Family

• Sequence:

  MTQKGSMKPVKKKKTEEPELEPLCCCEYIDRNGEKNHVATCLCDCQDLDEGCDRWITCKS
  LQPETCERIMDTISDRLRIPWLRGAKKVNISIIPPLVLLPVFLHVASWHFLLGVVVLTSL
  PVLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLQEVVPKGRVGPVQLAVLTCGLFL
  ILLALHRAKKNPGYLSNPASGDRSLSSSQLECLSRKGQEKTKGFPGADMSGSLNNRTTKD
  DPKGSSKMPAGSPTKAKEDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESN
  HQAFILALLIFLLTSVYGITLTLDTICRDRSVFTALFYCPGVYANYSSALSFTCVWYSVI
  ITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGLLG

• Sequence length: 409

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CROHN'S DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	27536776		★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	37978524	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	36456979	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	30658672		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	30658672	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	30658672		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	30658672	Associate	★☆☆☆☆ Found in Text Mining only
Precursor Cell Lymphoblastic Leukemia Lymphoma	Lymphoblastic Leukemia	BEFREE	27536776		★☆☆☆☆ Found in Text Mining only