SERHL2 (serine hydrolase like 2)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 253190
Gene name Serine hydrolase like 2
Gene symbol SERHL2
Synonyms (NCBI Gene)
dJ222E13.1
Chromosome 22
Chromosome location 22q13.2
miRNA miRNA information provided by mirtarbase database.
13
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (13)
miRTarBase ID miRNA Experiments Reference
MIRT2099860 hsa-miR-145 CLIP-seq
MIRT2099861 hsa-miR-214 CLIP-seq
MIRT2099862 hsa-miR-3147 CLIP-seq
MIRT2099863 hsa-miR-3616-5p CLIP-seq
MIRT2099864 hsa-miR-3619-5p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (5)
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IEA
GO:0005777 Component Peroxisome IEA
GO:0016787 Function Hydrolase activity IBA
GO:0016787 Function Hydrolase activity IEA
GO:0048471 Component Perinuclear region of cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
619045 29446 ENSG00000183569
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H4I8
Protein name Serine hydrolase-like protein 2 (EC 3.1.-.-)
Protein function Probable serine hydrolase. May be related to cell muscle hypertrophy.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00561 Abhydrolase_1 33 → 293 alpha/beta hydrolase fold Domain
Sequence
Sequence length 314
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
OCULAR HYPERTENSION — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations