Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	23627
Gene name	Prion like protein doppel
Gene symbol	PRND
Synonyms (NCBI Gene)	DOPPELDPLPrPLPdJ1068H6.4
Chromosome	20
Chromosome location	20p13
Summary	This gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored g

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miRTarBase ID	miRNA	Experiments	Reference
MIRT037276	hsa-miR-877-5p	CLASH	23622248
MIRT1264829	hsa-miR-1253	CLIP-seq
MIRT1264830	hsa-miR-1254	CLIP-seq
MIRT1264831	hsa-miR-1275	CLIP-seq
MIRT1264832	hsa-miR-1293	CLIP-seq
MIRT1264833	hsa-miR-137	CLIP-seq
MIRT1264834	hsa-miR-141	CLIP-seq
MIRT1264835	hsa-miR-142-3p	CLIP-seq
MIRT1264836	hsa-miR-153	CLIP-seq
MIRT1264837	hsa-miR-1827	CLIP-seq
MIRT1264838	hsa-miR-183	CLIP-seq
MIRT1264839	hsa-miR-200a	CLIP-seq
MIRT1264840	hsa-miR-2467-3p	CLIP-seq
MIRT1264841	hsa-miR-25	CLIP-seq
MIRT1264842	hsa-miR-2964a-5p	CLIP-seq
MIRT1264843	hsa-miR-3116	CLIP-seq
MIRT1264844	hsa-miR-3120-3p	CLIP-seq
MIRT1264845	hsa-miR-3163	CLIP-seq
MIRT1264846	hsa-miR-3165	CLIP-seq
MIRT1264847	hsa-miR-3173-3p	CLIP-seq
MIRT1264848	hsa-miR-3174	CLIP-seq
MIRT1264849	hsa-miR-3175	CLIP-seq
MIRT1264850	hsa-miR-3192	CLIP-seq
MIRT1264851	hsa-miR-32	CLIP-seq
MIRT1264852	hsa-miR-3202	CLIP-seq
MIRT1264853	hsa-miR-329	CLIP-seq
MIRT1264854	hsa-miR-345	CLIP-seq
MIRT1264855	hsa-miR-3612	CLIP-seq
MIRT1264856	hsa-miR-3622a-3p	CLIP-seq
MIRT1264857	hsa-miR-3622b-3p	CLIP-seq
MIRT1264858	hsa-miR-362-3p	CLIP-seq
MIRT1264859	hsa-miR-363	CLIP-seq
MIRT1264860	hsa-miR-367	CLIP-seq
MIRT1264861	hsa-miR-3689a-3p	CLIP-seq
MIRT1264862	hsa-miR-3689c	CLIP-seq
MIRT1264863	hsa-miR-3689d	CLIP-seq
MIRT1264864	hsa-miR-3926	CLIP-seq
MIRT1264865	hsa-miR-3929	CLIP-seq
MIRT1264866	hsa-miR-4260	CLIP-seq
MIRT1264867	hsa-miR-4261	CLIP-seq
MIRT1264868	hsa-miR-4269	CLIP-seq
MIRT1264869	hsa-miR-431	CLIP-seq
MIRT1264870	hsa-miR-4329	CLIP-seq
MIRT1264871	hsa-miR-4419b	CLIP-seq
MIRT1264872	hsa-miR-4433	CLIP-seq
MIRT1264873	hsa-miR-4434	CLIP-seq
MIRT1264874	hsa-miR-4459	CLIP-seq
MIRT1264875	hsa-miR-4470	CLIP-seq
MIRT1264876	hsa-miR-4478	CLIP-seq
MIRT1264877	hsa-miR-448	CLIP-seq
MIRT1264878	hsa-miR-4483	CLIP-seq
MIRT1264879	hsa-miR-4487	CLIP-seq
MIRT1264880	hsa-miR-4514	CLIP-seq
MIRT1264881	hsa-miR-4516	CLIP-seq
MIRT1264882	hsa-miR-4525	CLIP-seq
MIRT1264883	hsa-miR-4533	CLIP-seq
MIRT1264884	hsa-miR-4635	CLIP-seq
MIRT1264885	hsa-miR-4665-5p	CLIP-seq
MIRT1264886	hsa-miR-4692	CLIP-seq
MIRT1264887	hsa-miR-4700-3p	CLIP-seq
MIRT1264888	hsa-miR-4705	CLIP-seq
MIRT1264889	hsa-miR-4712-3p	CLIP-seq
MIRT1264890	hsa-miR-4723-5p	CLIP-seq
MIRT1264891	hsa-miR-4728-5p	CLIP-seq
MIRT1264892	hsa-miR-4742-5p	CLIP-seq
MIRT1264893	hsa-miR-4768-3p	CLIP-seq
MIRT1264894	hsa-miR-4773	CLIP-seq
MIRT1264895	hsa-miR-4779	CLIP-seq
MIRT1264896	hsa-miR-4786-5p	CLIP-seq
MIRT1264897	hsa-miR-485-5p	CLIP-seq
MIRT1264898	hsa-miR-488	CLIP-seq
MIRT1264899	hsa-miR-508-5p	CLIP-seq
MIRT1264900	hsa-miR-544b	CLIP-seq
MIRT1264901	hsa-miR-545	CLIP-seq
MIRT1264902	hsa-miR-548s	CLIP-seq
MIRT1264903	hsa-miR-625	CLIP-seq
MIRT1264904	hsa-miR-626	CLIP-seq
MIRT1264905	hsa-miR-629	CLIP-seq
MIRT1264906	hsa-miR-650	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT1264908	hsa-miR-766	CLIP-seq
MIRT1264909	hsa-miR-921	CLIP-seq
MIRT1264910	hsa-miR-92a	CLIP-seq
MIRT1264911	hsa-miR-92b	CLIP-seq
MIRT1264837	hsa-miR-1827	CLIP-seq
MIRT1264840	hsa-miR-2467-3p	CLIP-seq
MIRT1264850	hsa-miR-3192	CLIP-seq
MIRT1264855	hsa-miR-3612	CLIP-seq
MIRT1264861	hsa-miR-3689a-3p	CLIP-seq
MIRT1264862	hsa-miR-3689c	CLIP-seq
MIRT1264891	hsa-miR-4728-5p	CLIP-seq
MIRT1264897	hsa-miR-485-5p	CLIP-seq
MIRT1264906	hsa-miR-650	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT2077884	hsa-miR-1228	CLIP-seq
MIRT1264830	hsa-miR-1254	CLIP-seq
MIRT2077885	hsa-miR-1285	CLIP-seq
MIRT1264832	hsa-miR-1293	CLIP-seq
MIRT1264835	hsa-miR-142-3p	CLIP-seq
MIRT2077886	hsa-miR-2861	CLIP-seq
MIRT1264843	hsa-miR-3116	CLIP-seq
MIRT1264846	hsa-miR-3165	CLIP-seq
MIRT1264848	hsa-miR-3174	CLIP-seq
MIRT1264852	hsa-miR-3202	CLIP-seq
MIRT1264856	hsa-miR-3622a-3p	CLIP-seq
MIRT1264857	hsa-miR-3622b-3p	CLIP-seq
MIRT1264863	hsa-miR-3689d	CLIP-seq
MIRT1264864	hsa-miR-3926	CLIP-seq
MIRT1264872	hsa-miR-4433	CLIP-seq
MIRT1264874	hsa-miR-4459	CLIP-seq
MIRT1264875	hsa-miR-4470	CLIP-seq
MIRT1264878	hsa-miR-4483	CLIP-seq
MIRT1264883	hsa-miR-4533	CLIP-seq
MIRT1264893	hsa-miR-4768-3p	CLIP-seq
MIRT1264899	hsa-miR-508-5p	CLIP-seq
MIRT1264900	hsa-miR-544b	CLIP-seq
MIRT2077887	hsa-miR-548a-3p	CLIP-seq
MIRT2077888	hsa-miR-548e	CLIP-seq
MIRT2077889	hsa-miR-548f	CLIP-seq
MIRT1264902	hsa-miR-548s	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT1264908	hsa-miR-766	CLIP-seq
MIRT1264909	hsa-miR-921	CLIP-seq
MIRT2304400	hsa-miR-106a	CLIP-seq
MIRT2304401	hsa-miR-106b	CLIP-seq
MIRT2304402	hsa-miR-1226	CLIP-seq
MIRT2304403	hsa-miR-1245	CLIP-seq
MIRT1264830	hsa-miR-1254	CLIP-seq
MIRT2077885	hsa-miR-1285	CLIP-seq
MIRT1264834	hsa-miR-141	CLIP-seq
MIRT1264835	hsa-miR-142-3p	CLIP-seq
MIRT2304404	hsa-miR-17	CLIP-seq
MIRT2304405	hsa-miR-181a	CLIP-seq
MIRT2304406	hsa-miR-181b	CLIP-seq
MIRT2304407	hsa-miR-181c	CLIP-seq
MIRT2304408	hsa-miR-181d	CLIP-seq
MIRT1264837	hsa-miR-1827	CLIP-seq
MIRT1264839	hsa-miR-200a	CLIP-seq
MIRT2304409	hsa-miR-20a	CLIP-seq
MIRT2304410	hsa-miR-20b	CLIP-seq
MIRT2077886	hsa-miR-2861	CLIP-seq
MIRT1264842	hsa-miR-2964a-5p	CLIP-seq
MIRT1264843	hsa-miR-3116	CLIP-seq
MIRT1264846	hsa-miR-3165	CLIP-seq
MIRT1264848	hsa-miR-3174	CLIP-seq
MIRT1264852	hsa-miR-3202	CLIP-seq
MIRT2304411	hsa-miR-326	CLIP-seq
MIRT2304412	hsa-miR-330-5p	CLIP-seq
MIRT1264854	hsa-miR-345	CLIP-seq
MIRT2304413	hsa-miR-3609	CLIP-seq
MIRT1264856	hsa-miR-3622a-3p	CLIP-seq
MIRT1264857	hsa-miR-3622b-3p	CLIP-seq
MIRT2304414	hsa-miR-3672	CLIP-seq
MIRT1264861	hsa-miR-3689a-3p	CLIP-seq
MIRT1264862	hsa-miR-3689c	CLIP-seq
MIRT1264863	hsa-miR-3689d	CLIP-seq
MIRT2304415	hsa-miR-378g	CLIP-seq
MIRT1264864	hsa-miR-3926	CLIP-seq
MIRT2304416	hsa-miR-4262	CLIP-seq
MIRT2304417	hsa-miR-4325	CLIP-seq
MIRT2304418	hsa-miR-4328	CLIP-seq
MIRT1264872	hsa-miR-4433	CLIP-seq
MIRT1264874	hsa-miR-4459	CLIP-seq
MIRT2304419	hsa-miR-4486	CLIP-seq
MIRT2304420	hsa-miR-4522	CLIP-seq
MIRT1264883	hsa-miR-4533	CLIP-seq
MIRT2304421	hsa-miR-4643	CLIP-seq
MIRT2304422	hsa-miR-466	CLIP-seq
MIRT1264888	hsa-miR-4705	CLIP-seq
MIRT1264891	hsa-miR-4728-5p	CLIP-seq
MIRT2304423	hsa-miR-4733-3p	CLIP-seq
MIRT1264893	hsa-miR-4768-3p	CLIP-seq
MIRT1264896	hsa-miR-4786-5p	CLIP-seq
MIRT2304424	hsa-miR-4789-3p	CLIP-seq
MIRT2304425	hsa-miR-4789-5p	CLIP-seq
MIRT2304426	hsa-miR-4796-3p	CLIP-seq
MIRT1264899	hsa-miR-508-5p	CLIP-seq
MIRT2304427	hsa-miR-519d	CLIP-seq
MIRT1264901	hsa-miR-545	CLIP-seq
MIRT2304428	hsa-miR-548ah	CLIP-seq
MIRT1264902	hsa-miR-548s	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT1264908	hsa-miR-766	CLIP-seq
MIRT1264909	hsa-miR-921	CLIP-seq
MIRT2304429	hsa-miR-93	CLIP-seq
MIRT2393035	hsa-miR-1273e	CLIP-seq
MIRT2077885	hsa-miR-1285	CLIP-seq
MIRT1264837	hsa-miR-1827	CLIP-seq
MIRT1264840	hsa-miR-2467-3p	CLIP-seq
MIRT1264850	hsa-miR-3192	CLIP-seq
MIRT1264855	hsa-miR-3612	CLIP-seq
MIRT2393036	hsa-miR-361-5p	CLIP-seq
MIRT1264861	hsa-miR-3689a-3p	CLIP-seq
MIRT1264862	hsa-miR-3689c	CLIP-seq
MIRT1264864	hsa-miR-3926	CLIP-seq
MIRT1264875	hsa-miR-4470	CLIP-seq
MIRT1264891	hsa-miR-4728-5p	CLIP-seq
MIRT1264896	hsa-miR-4786-5p	CLIP-seq
MIRT1264897	hsa-miR-485-5p	CLIP-seq
MIRT1264899	hsa-miR-508-5p	CLIP-seq
MIRT2393037	hsa-miR-520f	CLIP-seq
MIRT1264902	hsa-miR-548s	CLIP-seq
MIRT2393038	hsa-miR-636	CLIP-seq
MIRT1264906	hsa-miR-650	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT1264908	hsa-miR-766	CLIP-seq
MIRT2304400	hsa-miR-106a	CLIP-seq
MIRT2304401	hsa-miR-106b	CLIP-seq
MIRT2393035	hsa-miR-1273e	CLIP-seq
MIRT2077885	hsa-miR-1285	CLIP-seq
MIRT2304404	hsa-miR-17	CLIP-seq
MIRT2304409	hsa-miR-20a	CLIP-seq
MIRT2304410	hsa-miR-20b	CLIP-seq
MIRT2457204	hsa-miR-302a	CLIP-seq
MIRT2457205	hsa-miR-302b	CLIP-seq
MIRT2457206	hsa-miR-302c	CLIP-seq
MIRT2457207	hsa-miR-302d	CLIP-seq
MIRT2457208	hsa-miR-302e	CLIP-seq
MIRT2304414	hsa-miR-3672	CLIP-seq
MIRT2457209	hsa-miR-372	CLIP-seq
MIRT2457210	hsa-miR-373	CLIP-seq
MIRT2304420	hsa-miR-4522	CLIP-seq
MIRT2304427	hsa-miR-519d	CLIP-seq
MIRT2457211	hsa-miR-520a-3p	CLIP-seq
MIRT2457212	hsa-miR-520b	CLIP-seq
MIRT2457213	hsa-miR-520c-3p	CLIP-seq
MIRT2457214	hsa-miR-520d-3p	CLIP-seq
MIRT2457215	hsa-miR-520e	CLIP-seq
MIRT2393037	hsa-miR-520f	CLIP-seq
MIRT2457216	hsa-miR-548t	CLIP-seq
MIRT2393038	hsa-miR-636	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT2304429	hsa-miR-93	CLIP-seq
MIRT2601251	hsa-miR-10a	CLIP-seq
MIRT2601252	hsa-miR-10b	CLIP-seq
MIRT2077884	hsa-miR-1228	CLIP-seq
MIRT2077885	hsa-miR-1285	CLIP-seq
MIRT1264832	hsa-miR-1293	CLIP-seq
MIRT1264837	hsa-miR-1827	CLIP-seq
MIRT1264842	hsa-miR-2964a-5p	CLIP-seq
MIRT2601253	hsa-miR-3122	CLIP-seq
MIRT1264846	hsa-miR-3165	CLIP-seq
MIRT2601254	hsa-miR-339-5p	CLIP-seq
MIRT2601255	hsa-miR-3613-3p	CLIP-seq
MIRT1264856	hsa-miR-3622a-3p	CLIP-seq
MIRT1264857	hsa-miR-3622b-3p	CLIP-seq
MIRT2601256	hsa-miR-3665	CLIP-seq
MIRT2304414	hsa-miR-3672	CLIP-seq
MIRT1264861	hsa-miR-3689a-3p	CLIP-seq
MIRT1264862	hsa-miR-3689c	CLIP-seq
MIRT2601257	hsa-miR-371b-5p	CLIP-seq
MIRT2601258	hsa-miR-3913-5p	CLIP-seq
MIRT1264864	hsa-miR-3926	CLIP-seq
MIRT1264868	hsa-miR-4269	CLIP-seq
MIRT2601259	hsa-miR-4421	CLIP-seq
MIRT1264872	hsa-miR-4433	CLIP-seq
MIRT1264874	hsa-miR-4459	CLIP-seq
MIRT1264878	hsa-miR-4483	CLIP-seq
MIRT1264880	hsa-miR-4514	CLIP-seq
MIRT2304420	hsa-miR-4522	CLIP-seq
MIRT2601260	hsa-miR-4684-5p	CLIP-seq
MIRT1264886	hsa-miR-4692	CLIP-seq
MIRT1264891	hsa-miR-4728-5p	CLIP-seq
MIRT2601261	hsa-miR-4736	CLIP-seq
MIRT1264892	hsa-miR-4742-5p	CLIP-seq
MIRT1264893	hsa-miR-4768-3p	CLIP-seq
MIRT1264899	hsa-miR-508-5p	CLIP-seq
MIRT1264900	hsa-miR-544b	CLIP-seq
MIRT2601262	hsa-miR-548c-3p	CLIP-seq
MIRT1264902	hsa-miR-548s	CLIP-seq
MIRT2601263	hsa-miR-593	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT1264908	hsa-miR-766	CLIP-seq
MIRT2601264	hsa-miR-940	CLIP-seq
MIRT2601251	hsa-miR-10a	CLIP-seq
MIRT2601252	hsa-miR-10b	CLIP-seq
MIRT2077884	hsa-miR-1228	CLIP-seq
MIRT2077885	hsa-miR-1285	CLIP-seq
MIRT1264834	hsa-miR-141	CLIP-seq
MIRT1264837	hsa-miR-1827	CLIP-seq
MIRT1264839	hsa-miR-200a	CLIP-seq
MIRT1264842	hsa-miR-2964a-5p	CLIP-seq
MIRT2601253	hsa-miR-3122	CLIP-seq
MIRT1264846	hsa-miR-3165	CLIP-seq
MIRT2601254	hsa-miR-339-5p	CLIP-seq
MIRT1264856	hsa-miR-3622a-3p	CLIP-seq
MIRT1264857	hsa-miR-3622b-3p	CLIP-seq
MIRT2601256	hsa-miR-3665	CLIP-seq
MIRT2304414	hsa-miR-3672	CLIP-seq
MIRT1264861	hsa-miR-3689a-3p	CLIP-seq
MIRT1264862	hsa-miR-3689c	CLIP-seq
MIRT2601258	hsa-miR-3913-5p	CLIP-seq
MIRT1264868	hsa-miR-4269	CLIP-seq
MIRT2601259	hsa-miR-4421	CLIP-seq
MIRT1264875	hsa-miR-4470	CLIP-seq
MIRT1264880	hsa-miR-4514	CLIP-seq
MIRT2304420	hsa-miR-4522	CLIP-seq
MIRT2601260	hsa-miR-4684-5p	CLIP-seq
MIRT1264886	hsa-miR-4692	CLIP-seq
MIRT1264891	hsa-miR-4728-5p	CLIP-seq
MIRT2601261	hsa-miR-4736	CLIP-seq
MIRT1264892	hsa-miR-4742-5p	CLIP-seq
MIRT1264899	hsa-miR-508-5p	CLIP-seq
MIRT2601262	hsa-miR-548c-3p	CLIP-seq
MIRT2601263	hsa-miR-593	CLIP-seq
MIRT1264907	hsa-miR-661	CLIP-seq
MIRT1264908	hsa-miR-766	CLIP-seq
MIRT2601264	hsa-miR-940	CLIP-seq

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005507	Function	Copper ion binding	IBA
GO:0005507	Function	Copper ion binding	IDA	20411530
GO:0005507	Function	Copper ion binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	TAS
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006878	Process	Intracellular copper ion homeostasis	IBA
GO:0006878	Process	Intracellular copper ion homeostasis	IEA
GO:0007338	Process	Single fertilization	IEA
GO:0007340	Process	Acrosome reaction	IEA
GO:0007340	Process	Acrosome reaction	ISS
GO:0009897	Component	External side of plasma membrane	IDA	12200435
GO:0009897	Component	External side of plasma membrane	IEA
GO:0009897	Component	External side of plasma membrane	ISS
GO:0016020	Component	Membrane	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051260	Process	Protein homooligomerization	IEA
GO:0098552	Component	Side of membrane	IEA

MIM	HGNC	e!Ensembl
604263	15748	ENSG00000171864

Q9UKY0

Protein name

Prion-like protein doppel (PrPLP) (Prion protein 2)

Protein function

Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+) (PubMed:15218028, PubMed:20411530).

PDB

1LG4

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF11466	Doppel	1 → 30	Prion-like protein Doppel	Domain
PF00377	Prion	63 → 176	Prion/Doppel alpha-helical domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level). {ECO:0000269|PubMed:12200435}.

Sequence

MRKHLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFI
KQGRKLDIDFGAEGNRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINATQAANQGEF
QKPDNKLHQQVLWRLVQELCSLKHCEFWLERGAGLRVTMHQPVLLCLLALIWLTVK

Sequence length

176

Interactions

View interactions

	Reactome
			Post-translational modification: synthesis of GPI-anchored proteins

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CREUTZFELDT JACOB DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (24)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	22453181	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety Disorder	BEFREE	22453181		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety disorder	Pubtator	22453181	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	22453181		★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	15274317, 17390034, 18607068		★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	Pubtator	15274317, 16309242, 17201176, 18607068, 18936526, 20981146	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain neoplasms	Pubtator	18936526	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	22147650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Creutzfeldt-Jakob Disease, Sporadic	Creutzfeldt-Jakob disease	BEFREE	11702213, 17047093		★★★★★ ★☆☆☆☆ Found in Text Mining only
Delusions	Delusions	BEFREE	22453181		★★★★★ ★☆☆☆☆ Found in Text Mining only
Encephalopathies	Epileptic encephalopathy	BEFREE	22147650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	15274317	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	18607068, 20981146	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	17390034		★★★★★ ★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	Pubtator	15274317	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mild cognitive disorder	Cognitive disorder	BEFREE	22453181		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	15755294	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	17390034		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	22147650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	15449459		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	22147650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	22147650	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Psychomotor Agitation	Psychiatric disorders	Pubtator	22453181	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	15274317	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only

PRND (prion like protein doppel)