MKRN1 (makorin ring finger protein 1)

Gene

• Entrez ID: 23608
• Gene name: Makorin ring finger protein 1
• Gene symbol: MKRN1
• Synonyms (NCBI Gene): RNF61
• Chromosome: 7
• Chromosome location: 7q34
• Summary: This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target protei

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT002511	hsa-miR-373-3p	Microarray	15685193
MIRT019801	hsa-miR-375	Microarray	20215506
MIRT002511	hsa-miR-373-3p	Microarray	15685193
MIRT051838	hsa-let-7c-5p	CLASH	23622248
MIRT048130	hsa-miR-197-3p	CLASH	23622248
MIRT040519	hsa-miR-574-3p	CLASH	23622248
MIRT440234	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440233	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440234	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727187	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727186	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727184	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727185	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440233	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT1150307	hsa-miR-106a	CLIP-seq
MIRT1150308	hsa-miR-106b	CLIP-seq
MIRT1150309	hsa-miR-1224-5p	CLIP-seq
MIRT1150310	hsa-miR-1243	CLIP-seq
MIRT1150311	hsa-miR-1253	CLIP-seq
MIRT1150312	hsa-miR-1255a	CLIP-seq
MIRT1150313	hsa-miR-1255b	CLIP-seq
MIRT1150314	hsa-miR-1273d	CLIP-seq
MIRT1150315	hsa-miR-140-3p	CLIP-seq
MIRT1150316	hsa-miR-147	CLIP-seq
MIRT1150317	hsa-miR-17	CLIP-seq
MIRT1150318	hsa-miR-1909	CLIP-seq
MIRT1150319	hsa-miR-1912	CLIP-seq
MIRT1150320	hsa-miR-199a-3p	CLIP-seq
MIRT1150321	hsa-miR-199b-3p	CLIP-seq
MIRT1150322	hsa-miR-19a	CLIP-seq
MIRT1150323	hsa-miR-19b	CLIP-seq
MIRT1150324	hsa-miR-200b	CLIP-seq
MIRT1150325	hsa-miR-200c	CLIP-seq
MIRT1150326	hsa-miR-204	CLIP-seq
MIRT1150327	hsa-miR-20a	CLIP-seq
MIRT1150328	hsa-miR-20b	CLIP-seq
MIRT1150329	hsa-miR-211	CLIP-seq
MIRT1150330	hsa-miR-214	CLIP-seq
MIRT1150331	hsa-miR-217	CLIP-seq
MIRT1150332	hsa-miR-302a	CLIP-seq
MIRT1150333	hsa-miR-302b	CLIP-seq
MIRT1150334	hsa-miR-302c	CLIP-seq
MIRT1150335	hsa-miR-302d	CLIP-seq
MIRT1150336	hsa-miR-302e	CLIP-seq
MIRT1150337	hsa-miR-3064-3p	CLIP-seq
MIRT1150338	hsa-miR-3065-5p	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT1150340	hsa-miR-3122	CLIP-seq
MIRT1150341	hsa-miR-3129-5p	CLIP-seq
MIRT1150342	hsa-miR-3130-5p	CLIP-seq
MIRT1150343	hsa-miR-3140-3p	CLIP-seq
MIRT1150344	hsa-miR-3145-5p	CLIP-seq
MIRT1150345	hsa-miR-3148	CLIP-seq
MIRT1150346	hsa-miR-3153	CLIP-seq
MIRT1150347	hsa-miR-324-5p	CLIP-seq
MIRT1150348	hsa-miR-338-5p	CLIP-seq
MIRT1150349	hsa-miR-34c-3p	CLIP-seq
MIRT1150350	hsa-miR-3619-5p	CLIP-seq
MIRT1150351	hsa-miR-3654	CLIP-seq
MIRT1150352	hsa-miR-372	CLIP-seq
MIRT1150353	hsa-miR-373	CLIP-seq
MIRT1150354	hsa-miR-377	CLIP-seq
MIRT1150355	hsa-miR-3913-5p	CLIP-seq
MIRT1150356	hsa-miR-3978	CLIP-seq
MIRT1150357	hsa-miR-409-5p	CLIP-seq
MIRT1150358	hsa-miR-4252	CLIP-seq
MIRT1150359	hsa-miR-4261	CLIP-seq
MIRT1150360	hsa-miR-4287	CLIP-seq
MIRT1150361	hsa-miR-429	CLIP-seq
MIRT1150362	hsa-miR-4291	CLIP-seq
MIRT1150363	hsa-miR-4330	CLIP-seq
MIRT1150364	hsa-miR-4418	CLIP-seq
MIRT1150365	hsa-miR-4436b-3p	CLIP-seq
MIRT1150366	hsa-miR-4457	CLIP-seq
MIRT1150367	hsa-miR-4482	CLIP-seq
MIRT1150368	hsa-miR-4496	CLIP-seq
MIRT1150369	hsa-miR-4649-3p	CLIP-seq
MIRT1150370	hsa-miR-4668-5p	CLIP-seq
MIRT1150371	hsa-miR-4685-3p	CLIP-seq
MIRT1150372	hsa-miR-4686	CLIP-seq
MIRT1150373	hsa-miR-4698	CLIP-seq
MIRT1150374	hsa-miR-4727-5p	CLIP-seq
MIRT1150375	hsa-miR-4731-3p	CLIP-seq
MIRT1150376	hsa-miR-4751	CLIP-seq
MIRT1150377	hsa-miR-4769-3p	CLIP-seq
MIRT1150378	hsa-miR-4786-5p	CLIP-seq
MIRT1150379	hsa-miR-4797-5p	CLIP-seq
MIRT1150380	hsa-miR-4801	CLIP-seq
MIRT1150381	hsa-miR-486-5p	CLIP-seq
MIRT1150382	hsa-miR-495	CLIP-seq
MIRT1150383	hsa-miR-508-5p	CLIP-seq
MIRT1150384	hsa-miR-509-3-5p	CLIP-seq
MIRT1150385	hsa-miR-509-5p	CLIP-seq
MIRT1150386	hsa-miR-515-3p	CLIP-seq
MIRT1150387	hsa-miR-519a	CLIP-seq
MIRT1150388	hsa-miR-519b-3p	CLIP-seq
MIRT1150389	hsa-miR-519c-3p	CLIP-seq
MIRT1150390	hsa-miR-519d	CLIP-seq
MIRT1150391	hsa-miR-519e	CLIP-seq
MIRT1150392	hsa-miR-520a-3p	CLIP-seq
MIRT1150393	hsa-miR-520b	CLIP-seq
MIRT1150394	hsa-miR-520c-3p	CLIP-seq
MIRT1150395	hsa-miR-520d-3p	CLIP-seq
MIRT1150396	hsa-miR-520d-5p	CLIP-seq
MIRT1150397	hsa-miR-520e	CLIP-seq
MIRT1150398	hsa-miR-520f	CLIP-seq
MIRT1150399	hsa-miR-524-5p	CLIP-seq
MIRT1150400	hsa-miR-548aa	CLIP-seq
MIRT1150401	hsa-miR-548ac	CLIP-seq
MIRT1150402	hsa-miR-548d-3p	CLIP-seq
MIRT1150403	hsa-miR-548l	CLIP-seq
MIRT1150404	hsa-miR-548m	CLIP-seq
MIRT1150405	hsa-miR-548n	CLIP-seq
MIRT1150406	hsa-miR-548t	CLIP-seq
MIRT1150407	hsa-miR-548z	CLIP-seq
MIRT1150408	hsa-miR-550a	CLIP-seq
MIRT1150409	hsa-miR-581	CLIP-seq
MIRT1150410	hsa-miR-600	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT1150412	hsa-miR-660	CLIP-seq
MIRT1150413	hsa-miR-665	CLIP-seq
MIRT1150414	hsa-miR-761	CLIP-seq
MIRT1150415	hsa-miR-873	CLIP-seq
MIRT1150416	hsa-miR-875-3p	CLIP-seq
MIRT1150417	hsa-miR-885-5p	CLIP-seq
MIRT1150418	hsa-miR-922	CLIP-seq
MIRT1150419	hsa-miR-93	CLIP-seq
MIRT1150330	hsa-miR-214	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT1150350	hsa-miR-3619-5p	CLIP-seq
MIRT1150354	hsa-miR-377	CLIP-seq
MIRT1150362	hsa-miR-4291	CLIP-seq
MIRT1150369	hsa-miR-4649-3p	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT1150414	hsa-miR-761	CLIP-seq
MIRT1150418	hsa-miR-922	CLIP-seq
MIRT1150307	hsa-miR-106a	CLIP-seq
MIRT1150308	hsa-miR-106b	CLIP-seq
MIRT2042829	hsa-miR-1228	CLIP-seq
MIRT1150311	hsa-miR-1253	CLIP-seq
MIRT2042830	hsa-miR-1266	CLIP-seq
MIRT2042831	hsa-miR-129-3p	CLIP-seq
MIRT2042832	hsa-miR-1305	CLIP-seq
MIRT1150315	hsa-miR-140-3p	CLIP-seq
MIRT1150316	hsa-miR-147	CLIP-seq
MIRT1150317	hsa-miR-17	CLIP-seq
MIRT1150319	hsa-miR-1912	CLIP-seq
MIRT1150320	hsa-miR-199a-3p	CLIP-seq
MIRT1150321	hsa-miR-199b-3p	CLIP-seq
MIRT1150322	hsa-miR-19a	CLIP-seq
MIRT1150323	hsa-miR-19b	CLIP-seq
MIRT1150327	hsa-miR-20a	CLIP-seq
MIRT1150328	hsa-miR-20b	CLIP-seq
MIRT1150337	hsa-miR-3064-3p	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT1150341	hsa-miR-3129-5p	CLIP-seq
MIRT1150342	hsa-miR-3130-5p	CLIP-seq
MIRT1150346	hsa-miR-3153	CLIP-seq
MIRT2042833	hsa-miR-3184	CLIP-seq
MIRT2042834	hsa-miR-342-3p	CLIP-seq
MIRT1150357	hsa-miR-409-5p	CLIP-seq
MIRT2042835	hsa-miR-421	CLIP-seq
MIRT2042836	hsa-miR-423-5p	CLIP-seq
MIRT2042837	hsa-miR-4270	CLIP-seq
MIRT2042838	hsa-miR-4441	CLIP-seq
MIRT1150366	hsa-miR-4457	CLIP-seq
MIRT1150367	hsa-miR-4482	CLIP-seq
MIRT2042839	hsa-miR-4518	CLIP-seq
MIRT2042840	hsa-miR-4536	CLIP-seq
MIRT1150370	hsa-miR-4668-5p	CLIP-seq
MIRT2042841	hsa-miR-4690-3p	CLIP-seq
MIRT2042842	hsa-miR-4709-5p	CLIP-seq
MIRT2042843	hsa-miR-4710	CLIP-seq
MIRT1150375	hsa-miR-4731-3p	CLIP-seq
MIRT1150378	hsa-miR-4786-5p	CLIP-seq
MIRT1150380	hsa-miR-4801	CLIP-seq
MIRT2042844	hsa-miR-483-3p	CLIP-seq
MIRT2042845	hsa-miR-5095	CLIP-seq
MIRT1150387	hsa-miR-519a	CLIP-seq
MIRT1150388	hsa-miR-519b-3p	CLIP-seq
MIRT1150389	hsa-miR-519c-3p	CLIP-seq
MIRT1150390	hsa-miR-519d	CLIP-seq
MIRT1150400	hsa-miR-548aa	CLIP-seq
MIRT2042846	hsa-miR-548c-3p	CLIP-seq
MIRT2042847	hsa-miR-570	CLIP-seq
MIRT2042848	hsa-miR-580	CLIP-seq
MIRT1150409	hsa-miR-581	CLIP-seq
MIRT2042849	hsa-miR-603	CLIP-seq
MIRT1150419	hsa-miR-93	CLIP-seq
MIRT1150307	hsa-miR-106a	CLIP-seq
MIRT1150308	hsa-miR-106b	CLIP-seq
MIRT2272407	hsa-miR-1197	CLIP-seq
MIRT2272408	hsa-miR-1226	CLIP-seq
MIRT2042829	hsa-miR-1228	CLIP-seq
MIRT2272409	hsa-miR-1231	CLIP-seq
MIRT1150311	hsa-miR-1253	CLIP-seq
MIRT1150312	hsa-miR-1255a	CLIP-seq
MIRT1150313	hsa-miR-1255b	CLIP-seq
MIRT2042830	hsa-miR-1266	CLIP-seq
MIRT2272410	hsa-miR-1293	CLIP-seq
MIRT2042831	hsa-miR-129-3p	CLIP-seq
MIRT2042832	hsa-miR-1305	CLIP-seq
MIRT1150315	hsa-miR-140-3p	CLIP-seq
MIRT1150317	hsa-miR-17	CLIP-seq
MIRT2272411	hsa-miR-181a	CLIP-seq
MIRT2272412	hsa-miR-181b	CLIP-seq
MIRT2272413	hsa-miR-181c	CLIP-seq
MIRT2272414	hsa-miR-181d	CLIP-seq
MIRT2272415	hsa-miR-185	CLIP-seq
MIRT1150318	hsa-miR-1909	CLIP-seq
MIRT1150319	hsa-miR-1912	CLIP-seq
MIRT2272416	hsa-miR-197	CLIP-seq
MIRT1150324	hsa-miR-200b	CLIP-seq
MIRT1150325	hsa-miR-200c	CLIP-seq
MIRT1150326	hsa-miR-204	CLIP-seq
MIRT1150327	hsa-miR-20a	CLIP-seq
MIRT1150328	hsa-miR-20b	CLIP-seq
MIRT1150329	hsa-miR-211	CLIP-seq
MIRT1150330	hsa-miR-214	CLIP-seq
MIRT2272417	hsa-miR-216a	CLIP-seq
MIRT1150331	hsa-miR-217	CLIP-seq
MIRT2272418	hsa-miR-2276	CLIP-seq
MIRT2272419	hsa-miR-2467-3p	CLIP-seq
MIRT1150337	hsa-miR-3064-3p	CLIP-seq
MIRT2272420	hsa-miR-3065-3p	CLIP-seq
MIRT1150338	hsa-miR-3065-5p	CLIP-seq
MIRT2272421	hsa-miR-3117-3p	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT1150342	hsa-miR-3130-5p	CLIP-seq
MIRT1150343	hsa-miR-3140-3p	CLIP-seq
MIRT1150344	hsa-miR-3145-5p	CLIP-seq
MIRT1150345	hsa-miR-3148	CLIP-seq
MIRT2272422	hsa-miR-3152-3p	CLIP-seq
MIRT2272423	hsa-miR-3187-3p	CLIP-seq
MIRT2272424	hsa-miR-3189-3p	CLIP-seq
MIRT1150347	hsa-miR-324-5p	CLIP-seq
MIRT2272425	hsa-miR-329	CLIP-seq
MIRT2272426	hsa-miR-330-3p	CLIP-seq
MIRT1150348	hsa-miR-338-5p	CLIP-seq
MIRT2042834	hsa-miR-342-3p	CLIP-seq
MIRT1150350	hsa-miR-3619-5p	CLIP-seq
MIRT2272427	hsa-miR-362-3p	CLIP-seq
MIRT2272428	hsa-miR-3689a-3p	CLIP-seq
MIRT2272429	hsa-miR-3689c	CLIP-seq
MIRT1150354	hsa-miR-377	CLIP-seq
MIRT2272430	hsa-miR-3918	CLIP-seq
MIRT2272431	hsa-miR-3925-5p	CLIP-seq
MIRT2272432	hsa-miR-3944-5p	CLIP-seq
MIRT1150357	hsa-miR-409-5p	CLIP-seq
MIRT2272433	hsa-miR-412	CLIP-seq
MIRT2042835	hsa-miR-421	CLIP-seq
MIRT1150358	hsa-miR-4252	CLIP-seq
MIRT2272434	hsa-miR-4254	CLIP-seq
MIRT2272435	hsa-miR-4262	CLIP-seq
MIRT2272436	hsa-miR-4269	CLIP-seq
MIRT2042837	hsa-miR-4270	CLIP-seq
MIRT1150360	hsa-miR-4287	CLIP-seq
MIRT1150361	hsa-miR-429	CLIP-seq
MIRT2272437	hsa-miR-4290	CLIP-seq
MIRT1150362	hsa-miR-4291	CLIP-seq
MIRT2272438	hsa-miR-4300	CLIP-seq
MIRT2272439	hsa-miR-4306	CLIP-seq
MIRT2272440	hsa-miR-432	CLIP-seq
MIRT1150364	hsa-miR-4418	CLIP-seq
MIRT2272441	hsa-miR-4435	CLIP-seq
MIRT1150365	hsa-miR-4436b-3p	CLIP-seq
MIRT2042838	hsa-miR-4441	CLIP-seq
MIRT1150367	hsa-miR-4482	CLIP-seq
MIRT2272442	hsa-miR-4483	CLIP-seq
MIRT2272443	hsa-miR-4506	CLIP-seq
MIRT2042839	hsa-miR-4518	CLIP-seq
MIRT2272444	hsa-miR-4535	CLIP-seq
MIRT2272445	hsa-miR-4644	CLIP-seq
MIRT1150369	hsa-miR-4649-3p	CLIP-seq
MIRT2272446	hsa-miR-4653-3p	CLIP-seq
MIRT2272447	hsa-miR-4661-3p	CLIP-seq
MIRT2272448	hsa-miR-4667-5p	CLIP-seq
MIRT1150370	hsa-miR-4668-5p	CLIP-seq
MIRT1150371	hsa-miR-4685-3p	CLIP-seq
MIRT2272449	hsa-miR-4687-5p	CLIP-seq
MIRT2042841	hsa-miR-4690-3p	CLIP-seq
MIRT1150373	hsa-miR-4698	CLIP-seq
MIRT2272450	hsa-miR-4700-5p	CLIP-seq
MIRT2272451	hsa-miR-4701-5p	CLIP-seq
MIRT2042842	hsa-miR-4709-5p	CLIP-seq
MIRT2272452	hsa-miR-4721	CLIP-seq
MIRT2272453	hsa-miR-4733-3p	CLIP-seq
MIRT2272454	hsa-miR-4772-3p	CLIP-seq
MIRT2272455	hsa-miR-4776-5p	CLIP-seq
MIRT2272456	hsa-miR-4795-3p	CLIP-seq
MIRT1150379	hsa-miR-4797-5p	CLIP-seq
MIRT2042844	hsa-miR-483-3p	CLIP-seq
MIRT2272457	hsa-miR-486-3p	CLIP-seq
MIRT2272458	hsa-miR-490-3p	CLIP-seq
MIRT1150383	hsa-miR-508-5p	CLIP-seq
MIRT1150384	hsa-miR-509-3-5p	CLIP-seq
MIRT1150385	hsa-miR-509-5p	CLIP-seq
MIRT2272459	hsa-miR-5096	CLIP-seq
MIRT1150390	hsa-miR-519d	CLIP-seq
MIRT1150396	hsa-miR-520d-5p	CLIP-seq
MIRT1150399	hsa-miR-524-5p	CLIP-seq
MIRT2042846	hsa-miR-548c-3p	CLIP-seq
MIRT1150403	hsa-miR-548l	CLIP-seq
MIRT1150405	hsa-miR-548n	CLIP-seq
MIRT2272460	hsa-miR-548s	CLIP-seq
MIRT2042847	hsa-miR-570	CLIP-seq
MIRT2272461	hsa-miR-576-3p	CLIP-seq
MIRT2272462	hsa-miR-588	CLIP-seq
MIRT2272463	hsa-miR-599	CLIP-seq
MIRT2042849	hsa-miR-603	CLIP-seq
MIRT2272464	hsa-miR-619	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT2272465	hsa-miR-637	CLIP-seq
MIRT2272466	hsa-miR-654-3p	CLIP-seq
MIRT1150413	hsa-miR-665	CLIP-seq
MIRT2272467	hsa-miR-711	CLIP-seq
MIRT1150414	hsa-miR-761	CLIP-seq
MIRT2272468	hsa-miR-769-5p	CLIP-seq
MIRT2272469	hsa-miR-920	CLIP-seq
MIRT1150418	hsa-miR-922	CLIP-seq
MIRT1150419	hsa-miR-93	CLIP-seq
MIRT2272470	hsa-miR-936	CLIP-seq
MIRT2272471	hsa-miR-944	CLIP-seq
MIRT2042829	hsa-miR-1228	CLIP-seq
MIRT2272411	hsa-miR-181a	CLIP-seq
MIRT2272412	hsa-miR-181b	CLIP-seq
MIRT2272413	hsa-miR-181c	CLIP-seq
MIRT2272414	hsa-miR-181d	CLIP-seq
MIRT1150319	hsa-miR-1912	CLIP-seq
MIRT1150330	hsa-miR-214	CLIP-seq
MIRT2272417	hsa-miR-216a	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT1150342	hsa-miR-3130-5p	CLIP-seq
MIRT1150350	hsa-miR-3619-5p	CLIP-seq
MIRT2390933	hsa-miR-3622a-3p	CLIP-seq
MIRT2390934	hsa-miR-3622b-3p	CLIP-seq
MIRT1150354	hsa-miR-377	CLIP-seq
MIRT1150357	hsa-miR-409-5p	CLIP-seq
MIRT2272435	hsa-miR-4262	CLIP-seq
MIRT1150362	hsa-miR-4291	CLIP-seq
MIRT1150367	hsa-miR-4482	CLIP-seq
MIRT1150369	hsa-miR-4649-3p	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT1150414	hsa-miR-761	CLIP-seq
MIRT1150418	hsa-miR-922	CLIP-seq
MIRT1150315	hsa-miR-140-3p	CLIP-seq
MIRT1150337	hsa-miR-3064-3p	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT1150369	hsa-miR-4649-3p	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT1150315	hsa-miR-140-3p	CLIP-seq
MIRT1150337	hsa-miR-3064-3p	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT2042829	hsa-miR-1228	CLIP-seq
MIRT1150311	hsa-miR-1253	CLIP-seq
MIRT1150312	hsa-miR-1255a	CLIP-seq
MIRT1150313	hsa-miR-1255b	CLIP-seq
MIRT2042830	hsa-miR-1266	CLIP-seq
MIRT2042831	hsa-miR-129-3p	CLIP-seq
MIRT2042832	hsa-miR-1305	CLIP-seq
MIRT1150315	hsa-miR-140-3p	CLIP-seq
MIRT2272411	hsa-miR-181a	CLIP-seq
MIRT2272412	hsa-miR-181b	CLIP-seq
MIRT2272413	hsa-miR-181c	CLIP-seq
MIRT2272414	hsa-miR-181d	CLIP-seq
MIRT1150318	hsa-miR-1909	CLIP-seq
MIRT1150324	hsa-miR-200b	CLIP-seq
MIRT1150325	hsa-miR-200c	CLIP-seq
MIRT2571340	hsa-miR-21	CLIP-seq
MIRT1150330	hsa-miR-214	CLIP-seq
MIRT2272417	hsa-miR-216a	CLIP-seq
MIRT1150331	hsa-miR-217	CLIP-seq
MIRT2571341	hsa-miR-2681	CLIP-seq
MIRT1150337	hsa-miR-3064-3p	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT1150346	hsa-miR-3153	CLIP-seq
MIRT2571342	hsa-miR-3157-3p	CLIP-seq
MIRT2571343	hsa-miR-3183	CLIP-seq
MIRT2042833	hsa-miR-3184	CLIP-seq
MIRT2272424	hsa-miR-3189-3p	CLIP-seq
MIRT2272425	hsa-miR-329	CLIP-seq
MIRT2571344	hsa-miR-337-3p	CLIP-seq
MIRT2571345	hsa-miR-33a	CLIP-seq
MIRT2571346	hsa-miR-33b	CLIP-seq
MIRT2571347	hsa-miR-3613-3p	CLIP-seq
MIRT1150350	hsa-miR-3619-5p	CLIP-seq
MIRT2390933	hsa-miR-3622a-3p	CLIP-seq
MIRT2390934	hsa-miR-3622b-3p	CLIP-seq
MIRT2272427	hsa-miR-362-3p	CLIP-seq
MIRT2571348	hsa-miR-3658	CLIP-seq
MIRT2571349	hsa-miR-3676	CLIP-seq
MIRT2571350	hsa-miR-3685	CLIP-seq
MIRT2272428	hsa-miR-3689a-3p	CLIP-seq
MIRT2272429	hsa-miR-3689c	CLIP-seq
MIRT1150354	hsa-miR-377	CLIP-seq
MIRT2571351	hsa-miR-384	CLIP-seq
MIRT1150357	hsa-miR-409-5p	CLIP-seq
MIRT2042835	hsa-miR-421	CLIP-seq
MIRT2042836	hsa-miR-423-5p	CLIP-seq
MIRT2272435	hsa-miR-4262	CLIP-seq
MIRT2042837	hsa-miR-4270	CLIP-seq
MIRT1150361	hsa-miR-429	CLIP-seq
MIRT1150362	hsa-miR-4291	CLIP-seq
MIRT2272438	hsa-miR-4300	CLIP-seq
MIRT1150364	hsa-miR-4418	CLIP-seq
MIRT2042838	hsa-miR-4441	CLIP-seq
MIRT1150366	hsa-miR-4457	CLIP-seq
MIRT2042839	hsa-miR-4518	CLIP-seq
MIRT2571352	hsa-miR-4633-5p	CLIP-seq
MIRT2571353	hsa-miR-4637	CLIP-seq
MIRT2571354	hsa-miR-4645-3p	CLIP-seq
MIRT1150369	hsa-miR-4649-3p	CLIP-seq
MIRT1150370	hsa-miR-4668-5p	CLIP-seq
MIRT2042841	hsa-miR-4690-3p	CLIP-seq
MIRT2042842	hsa-miR-4709-5p	CLIP-seq
MIRT2042843	hsa-miR-4710	CLIP-seq
MIRT2571355	hsa-miR-4723-3p	CLIP-seq
MIRT1150375	hsa-miR-4731-3p	CLIP-seq
MIRT1150380	hsa-miR-4801	CLIP-seq
MIRT2042844	hsa-miR-483-3p	CLIP-seq
MIRT1150384	hsa-miR-509-3-5p	CLIP-seq
MIRT1150385	hsa-miR-509-5p	CLIP-seq
MIRT2571356	hsa-miR-513c	CLIP-seq
MIRT2571357	hsa-miR-514b-5p	CLIP-seq
MIRT1150396	hsa-miR-520d-5p	CLIP-seq
MIRT1150399	hsa-miR-524-5p	CLIP-seq
MIRT2571358	hsa-miR-532-5p	CLIP-seq
MIRT2571359	hsa-miR-548ae	CLIP-seq
MIRT2571360	hsa-miR-548aj	CLIP-seq
MIRT2571361	hsa-miR-548am	CLIP-seq
MIRT2042846	hsa-miR-548c-3p	CLIP-seq
MIRT2571362	hsa-miR-548x	CLIP-seq
MIRT2571363	hsa-miR-549	CLIP-seq
MIRT2042847	hsa-miR-570	CLIP-seq
MIRT2042848	hsa-miR-580	CLIP-seq
MIRT2571364	hsa-miR-590-5p	CLIP-seq
MIRT2042849	hsa-miR-603	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT2571365	hsa-miR-630	CLIP-seq
MIRT1150414	hsa-miR-761	CLIP-seq
MIRT2571366	hsa-miR-874	CLIP-seq
MIRT2272469	hsa-miR-920	CLIP-seq
MIRT1150418	hsa-miR-922	CLIP-seq
MIRT2042829	hsa-miR-1228	CLIP-seq
MIRT1150311	hsa-miR-1253	CLIP-seq
MIRT1150312	hsa-miR-1255a	CLIP-seq
MIRT1150313	hsa-miR-1255b	CLIP-seq
MIRT2042830	hsa-miR-1266	CLIP-seq
MIRT2042831	hsa-miR-129-3p	CLIP-seq
MIRT2042832	hsa-miR-1305	CLIP-seq
MIRT1150315	hsa-miR-140-3p	CLIP-seq
MIRT2272411	hsa-miR-181a	CLIP-seq
MIRT2272412	hsa-miR-181b	CLIP-seq
MIRT2272413	hsa-miR-181c	CLIP-seq
MIRT2272414	hsa-miR-181d	CLIP-seq
MIRT1150318	hsa-miR-1909	CLIP-seq
MIRT1150324	hsa-miR-200b	CLIP-seq
MIRT1150325	hsa-miR-200c	CLIP-seq
MIRT2571340	hsa-miR-21	CLIP-seq
MIRT1150330	hsa-miR-214	CLIP-seq
MIRT2272417	hsa-miR-216a	CLIP-seq
MIRT1150331	hsa-miR-217	CLIP-seq
MIRT2571341	hsa-miR-2681	CLIP-seq
MIRT1150337	hsa-miR-3064-3p	CLIP-seq
MIRT1150339	hsa-miR-3120-5p	CLIP-seq
MIRT2571343	hsa-miR-3183	CLIP-seq
MIRT2272424	hsa-miR-3189-3p	CLIP-seq
MIRT2272425	hsa-miR-329	CLIP-seq
MIRT2571344	hsa-miR-337-3p	CLIP-seq
MIRT2571345	hsa-miR-33a	CLIP-seq
MIRT2571346	hsa-miR-33b	CLIP-seq
MIRT2571347	hsa-miR-3613-3p	CLIP-seq
MIRT1150350	hsa-miR-3619-5p	CLIP-seq
MIRT2272427	hsa-miR-362-3p	CLIP-seq
MIRT2571348	hsa-miR-3658	CLIP-seq
MIRT2571349	hsa-miR-3676	CLIP-seq
MIRT2571350	hsa-miR-3685	CLIP-seq
MIRT2272428	hsa-miR-3689a-3p	CLIP-seq
MIRT2272429	hsa-miR-3689c	CLIP-seq
MIRT1150354	hsa-miR-377	CLIP-seq
MIRT2571351	hsa-miR-384	CLIP-seq
MIRT2042835	hsa-miR-421	CLIP-seq
MIRT2272435	hsa-miR-4262	CLIP-seq
MIRT2042837	hsa-miR-4270	CLIP-seq
MIRT1150361	hsa-miR-429	CLIP-seq
MIRT1150362	hsa-miR-4291	CLIP-seq
MIRT2272438	hsa-miR-4300	CLIP-seq
MIRT1150364	hsa-miR-4418	CLIP-seq
MIRT2042838	hsa-miR-4441	CLIP-seq
MIRT1150366	hsa-miR-4457	CLIP-seq
MIRT2042839	hsa-miR-4518	CLIP-seq
MIRT2571352	hsa-miR-4633-5p	CLIP-seq
MIRT2571353	hsa-miR-4637	CLIP-seq
MIRT2571354	hsa-miR-4645-3p	CLIP-seq
MIRT1150369	hsa-miR-4649-3p	CLIP-seq
MIRT1150370	hsa-miR-4668-5p	CLIP-seq
MIRT2042841	hsa-miR-4690-3p	CLIP-seq
MIRT2042842	hsa-miR-4709-5p	CLIP-seq
MIRT2571355	hsa-miR-4723-3p	CLIP-seq
MIRT1150375	hsa-miR-4731-3p	CLIP-seq
MIRT1150380	hsa-miR-4801	CLIP-seq
MIRT2042844	hsa-miR-483-3p	CLIP-seq
MIRT1150384	hsa-miR-509-3-5p	CLIP-seq
MIRT1150385	hsa-miR-509-5p	CLIP-seq
MIRT2571356	hsa-miR-513c	CLIP-seq
MIRT2571357	hsa-miR-514b-5p	CLIP-seq
MIRT1150396	hsa-miR-520d-5p	CLIP-seq
MIRT1150399	hsa-miR-524-5p	CLIP-seq
MIRT2571358	hsa-miR-532-5p	CLIP-seq
MIRT2571359	hsa-miR-548ae	CLIP-seq
MIRT2571360	hsa-miR-548aj	CLIP-seq
MIRT2571361	hsa-miR-548am	CLIP-seq
MIRT2042846	hsa-miR-548c-3p	CLIP-seq
MIRT2571362	hsa-miR-548x	CLIP-seq
MIRT2042847	hsa-miR-570	CLIP-seq
MIRT2571364	hsa-miR-590-5p	CLIP-seq
MIRT2042849	hsa-miR-603	CLIP-seq
MIRT1150411	hsa-miR-626	CLIP-seq
MIRT2571365	hsa-miR-630	CLIP-seq
MIRT1150414	hsa-miR-761	CLIP-seq
MIRT2272469	hsa-miR-920	CLIP-seq
MIRT1150418	hsa-miR-922	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IDA	19536131
GO:0000209	Process	Protein polyubiquitination	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0005515	Function	Protein binding	IPI	19536131, 32296183
GO:0005829	Component	Cytosol	TAS
GO:0008270	Function	Zinc ion binding	IEA
GO:0016567	Process	Protein ubiquitination	IBA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IDA	19536131
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	TAS

Other IDs

• MIM: 607754
• HGNC: 7112
• e!Ensembl: ENSG00000133606

Protein

• UniProt ID: Q9UHC7
• Protein name: E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1)
• Protein function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates a
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF18044	zf-CCCH_4	59 → 80	CCCH-type zinc finger	Domain
  PF00642	zf-CCCH	85 → 110	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Family
  PF18044	zf-CCCH_4	212 → 233	CCCH-type zinc finger	Domain
  PF00097	zf-C3HC4	281 → 334	Zinc finger, C3HC4 type (RING finger)	Domain
  PF14608	zf-CCCH_2	369 → 391		Domain
  PF15815	MKRN1_C	392 → 482	E3 ubiquitin-protein ligase makorin, C-terminal	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10843807, ECO:0000269|PubMed:16785614}.
• Sequence:

  MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVT
  CRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATAT
  ELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCG
  RTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCG
  LQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFG
  ILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILK
  YKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFW
  ELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDL
  DL

• Sequence length: 482

Pathways

Reactome:

AKT phosphorylates targets in the cytosol
Regulation of PTEN stability and activity
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ENDOMETRIOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenomatous Polyposis Coli	Multiple polyposis syndrome	BEFREE	29713058		★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	36938725	Inhibit	★☆☆☆☆ Found in Text Mining only
Cervical Intraepithelial Neoplasia	Cervical Intraepithelial Neoplasia	BEFREE	26817873		★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	30143610		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	22864571, 23104211		★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	30143610		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	30143610		★☆☆☆☆ Found in Text Mining only
Thyroid Carcinoma Anaplastic	Thyroid cancer	Pubtator	26680454	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	32737449	Associate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	39742262	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	26183061	Associate	★☆☆☆☆ Found in Text Mining only