Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23515
Gene name	MORC family CW-type zinc finger 3
Gene symbol	MORC3
Synonyms (NCBI Gene)	NXP2ZCW5ZCWCC3
Chromosome	21
Chromosome location	21q22.12
Summary	This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces mult

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020644	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT027287	hsa-miR-101-3p	Sequencing	20371350
MIRT028275	hsa-miR-32-5p	Sequencing	20371350
MIRT030797	hsa-miR-21-5p	Sequencing	20371350
MIRT048085	hsa-miR-197-3p	CLASH	23622248
MIRT556094	hsa-miR-153-3p	PAR-CLIP	21572407
MIRT556093	hsa-miR-5700	PAR-CLIP	21572407
MIRT027287	hsa-miR-101-3p	PAR-CLIP	21572407
MIRT556092	hsa-miR-144-3p	PAR-CLIP	21572407
MIRT085317	hsa-miR-218-2-3p	PAR-CLIP	21572407
MIRT085323	hsa-miR-758-5p	PAR-CLIP	21572407
MIRT085320	hsa-miR-545-5p	PAR-CLIP	21572407
MIRT085322	hsa-miR-622	PAR-CLIP	21572407
MIRT027287	hsa-miR-101-3p	PAR-CLIP	21572407
MIRT085321	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT085314	hsa-miR-30a-3p	PAR-CLIP	21572407
MIRT085316	hsa-miR-30d-3p	PAR-CLIP	21572407
MIRT085318	hsa-miR-30e-3p	PAR-CLIP	21572407
MIRT440219	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT440219	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT155523	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT155532	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT028275	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT556094	hsa-miR-153-3p	PAR-CLIP	21572407
MIRT556093	hsa-miR-5700	PAR-CLIP	21572407
MIRT027287	hsa-miR-101-3p	PAR-CLIP	21572407
MIRT556092	hsa-miR-144-3p	PAR-CLIP	21572407
MIRT085317	hsa-miR-218-2-3p	PAR-CLIP	21572407
MIRT085323	hsa-miR-758-5p	PAR-CLIP	21572407
MIRT085320	hsa-miR-545-5p	PAR-CLIP	21572407
MIRT085322	hsa-miR-622	PAR-CLIP	21572407
MIRT027287	hsa-miR-101-3p	PAR-CLIP	21572407
MIRT085321	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT085314	hsa-miR-30a-3p	PAR-CLIP	21572407
MIRT085316	hsa-miR-30d-3p	PAR-CLIP	21572407
MIRT085318	hsa-miR-30e-3p	PAR-CLIP	21572407
MIRT1155393	hsa-miR-101	CLIP-seq
MIRT1155394	hsa-miR-103b	CLIP-seq
MIRT1155395	hsa-miR-1207-3p	CLIP-seq
MIRT1155396	hsa-miR-1267	CLIP-seq
MIRT1155397	hsa-miR-129-3p	CLIP-seq
MIRT1155398	hsa-miR-1298	CLIP-seq
MIRT1155399	hsa-miR-1303	CLIP-seq
MIRT1155400	hsa-miR-144	CLIP-seq
MIRT1155401	hsa-miR-153	CLIP-seq
MIRT1155402	hsa-miR-183	CLIP-seq
MIRT1155403	hsa-miR-1911	CLIP-seq
MIRT1155404	hsa-miR-200b	CLIP-seq
MIRT1155405	hsa-miR-200c	CLIP-seq
MIRT1155406	hsa-miR-2054	CLIP-seq
MIRT1155407	hsa-miR-2110	CLIP-seq
MIRT1155408	hsa-miR-2116	CLIP-seq
MIRT1155409	hsa-miR-25	CLIP-seq
MIRT1155410	hsa-miR-3123	CLIP-seq
MIRT1155411	hsa-miR-3149	CLIP-seq
MIRT1155412	hsa-miR-3150a-3p	CLIP-seq
MIRT1155413	hsa-miR-3163	CLIP-seq
MIRT1155414	hsa-miR-32	CLIP-seq
MIRT1155415	hsa-miR-3622b-5p	CLIP-seq
MIRT1155416	hsa-miR-363	CLIP-seq
MIRT1155417	hsa-miR-3649	CLIP-seq
MIRT1155418	hsa-miR-3651	CLIP-seq
MIRT1155419	hsa-miR-367	CLIP-seq
MIRT1155420	hsa-miR-375	CLIP-seq
MIRT1155421	hsa-miR-376c	CLIP-seq
MIRT1155422	hsa-miR-380	CLIP-seq
MIRT1155423	hsa-miR-3925-5p	CLIP-seq
MIRT1155424	hsa-miR-3944-5p	CLIP-seq
MIRT1155425	hsa-miR-4260	CLIP-seq
MIRT1155426	hsa-miR-4271	CLIP-seq
MIRT1155427	hsa-miR-4278	CLIP-seq
MIRT1155428	hsa-miR-4282	CLIP-seq
MIRT1155429	hsa-miR-429	CLIP-seq
MIRT1155430	hsa-miR-4326	CLIP-seq
MIRT1155431	hsa-miR-4423-5p	CLIP-seq
MIRT1155432	hsa-miR-4424	CLIP-seq
MIRT1155433	hsa-miR-4436b-3p	CLIP-seq
MIRT1155434	hsa-miR-4464	CLIP-seq
MIRT1155435	hsa-miR-452	CLIP-seq
MIRT1155436	hsa-miR-4521	CLIP-seq
MIRT1155437	hsa-miR-4522	CLIP-seq
MIRT1155438	hsa-miR-455-5p	CLIP-seq
MIRT1155439	hsa-miR-4652-3p	CLIP-seq
MIRT1155440	hsa-miR-4659a-3p	CLIP-seq
MIRT1155441	hsa-miR-4659b-3p	CLIP-seq
MIRT1155442	hsa-miR-4676-3p	CLIP-seq
MIRT1155443	hsa-miR-4687-5p	CLIP-seq
MIRT1155444	hsa-miR-4688	CLIP-seq
MIRT1155445	hsa-miR-4725-3p	CLIP-seq
MIRT1155446	hsa-miR-4748	CLIP-seq
MIRT1155447	hsa-miR-4753-3p	CLIP-seq
MIRT1155448	hsa-miR-4761-3p	CLIP-seq
MIRT1155449	hsa-miR-4774-3p	CLIP-seq
MIRT1155450	hsa-miR-4797-5p	CLIP-seq
MIRT1155451	hsa-miR-500a	CLIP-seq
MIRT1155452	hsa-miR-502-5p	CLIP-seq
MIRT1155453	hsa-miR-548u	CLIP-seq
MIRT1155454	hsa-miR-584	CLIP-seq
MIRT1155455	hsa-miR-633	CLIP-seq
MIRT1155456	hsa-miR-758	CLIP-seq
MIRT1155457	hsa-miR-767-3p	CLIP-seq
MIRT1155458	hsa-miR-889	CLIP-seq
MIRT1155459	hsa-miR-92a	CLIP-seq
MIRT1155460	hsa-miR-92b	CLIP-seq
MIRT1155395	hsa-miR-1207-3p	CLIP-seq
MIRT2044512	hsa-miR-3613-3p	CLIP-seq
MIRT2044513	hsa-miR-3646	CLIP-seq
MIRT2044514	hsa-miR-3662	CLIP-seq
MIRT1155432	hsa-miR-4424	CLIP-seq
MIRT2044515	hsa-miR-4477a	CLIP-seq
MIRT2044516	hsa-miR-4503	CLIP-seq
MIRT2044517	hsa-miR-4698	CLIP-seq
MIRT2044518	hsa-miR-548ag	CLIP-seq
MIRT2044519	hsa-miR-548ai	CLIP-seq
MIRT2044520	hsa-miR-548m	CLIP-seq
MIRT2044521	hsa-miR-887	CLIP-seq
MIRT1155393	hsa-miR-101	CLIP-seq
MIRT1155396	hsa-miR-1267	CLIP-seq
MIRT2273704	hsa-miR-1284	CLIP-seq
MIRT1155400	hsa-miR-144	CLIP-seq
MIRT1155407	hsa-miR-2110	CLIP-seq
MIRT2273705	hsa-miR-3124-3p	CLIP-seq
MIRT2273706	hsa-miR-3143	CLIP-seq
MIRT1155411	hsa-miR-3149	CLIP-seq
MIRT1155412	hsa-miR-3150a-3p	CLIP-seq
MIRT2273707	hsa-miR-3180-5p	CLIP-seq
MIRT2273708	hsa-miR-338-5p	CLIP-seq
MIRT2044513	hsa-miR-3646	CLIP-seq
MIRT2273709	hsa-miR-3657	CLIP-seq
MIRT2044514	hsa-miR-3662	CLIP-seq
MIRT1155425	hsa-miR-4260	CLIP-seq
MIRT1155426	hsa-miR-4271	CLIP-seq
MIRT1155431	hsa-miR-4423-5p	CLIP-seq
MIRT2044515	hsa-miR-4477a	CLIP-seq
MIRT2044516	hsa-miR-4503	CLIP-seq
MIRT2273710	hsa-miR-4662a-3p	CLIP-seq
MIRT2273711	hsa-miR-4669	CLIP-seq
MIRT2044517	hsa-miR-4698	CLIP-seq
MIRT2273712	hsa-miR-4719	CLIP-seq
MIRT1155445	hsa-miR-4725-3p	CLIP-seq
MIRT2273713	hsa-miR-4729	CLIP-seq
MIRT1155449	hsa-miR-4774-3p	CLIP-seq
MIRT2273714	hsa-miR-487a	CLIP-seq
MIRT2273715	hsa-miR-513a-3p	CLIP-seq
MIRT2273716	hsa-miR-513b	CLIP-seq
MIRT2273717	hsa-miR-520a-5p	CLIP-seq
MIRT2273718	hsa-miR-525-5p	CLIP-seq
MIRT2273719	hsa-miR-543	CLIP-seq
MIRT2044518	hsa-miR-548ag	CLIP-seq
MIRT2044519	hsa-miR-548ai	CLIP-seq
MIRT2273720	hsa-miR-548c-3p	CLIP-seq
MIRT2044520	hsa-miR-548m	CLIP-seq
MIRT2273721	hsa-miR-579	CLIP-seq
MIRT1155454	hsa-miR-584	CLIP-seq
MIRT2273722	hsa-miR-587	CLIP-seq
MIRT2044521	hsa-miR-887	CLIP-seq
MIRT2572465	hsa-miR-1283	CLIP-seq
MIRT1155408	hsa-miR-2116	CLIP-seq
MIRT2572466	hsa-miR-23a	CLIP-seq
MIRT2572467	hsa-miR-23b	CLIP-seq
MIRT2572468	hsa-miR-23c	CLIP-seq
MIRT2572469	hsa-miR-2681	CLIP-seq
MIRT2572470	hsa-miR-3121-3p	CLIP-seq
MIRT2572471	hsa-miR-3148	CLIP-seq
MIRT2572472	hsa-miR-3190	CLIP-seq
MIRT2044512	hsa-miR-3613-3p	CLIP-seq
MIRT2044513	hsa-miR-3646	CLIP-seq
MIRT2044514	hsa-miR-3662	CLIP-seq
MIRT2572473	hsa-miR-3908	CLIP-seq
MIRT2572474	hsa-miR-3942-5p	CLIP-seq
MIRT2572475	hsa-miR-3973	CLIP-seq
MIRT2572476	hsa-miR-3978	CLIP-seq
MIRT2044515	hsa-miR-4477a	CLIP-seq
MIRT2044516	hsa-miR-4503	CLIP-seq
MIRT2044517	hsa-miR-4698	CLIP-seq
MIRT2572477	hsa-miR-4700-3p	CLIP-seq
MIRT2572478	hsa-miR-4703-5p	CLIP-seq
MIRT2572479	hsa-miR-4718	CLIP-seq
MIRT2273712	hsa-miR-4719	CLIP-seq
MIRT2572480	hsa-miR-4728-3p	CLIP-seq
MIRT2572481	hsa-miR-4752	CLIP-seq
MIRT2572482	hsa-miR-4766-3p	CLIP-seq
MIRT2572483	hsa-miR-490-3p	CLIP-seq
MIRT1155451	hsa-miR-500a	CLIP-seq
MIRT2273715	hsa-miR-513a-3p	CLIP-seq
MIRT2273716	hsa-miR-513b	CLIP-seq
MIRT2572484	hsa-miR-520g	CLIP-seq
MIRT2572485	hsa-miR-520h	CLIP-seq
MIRT2572486	hsa-miR-548a-3p	CLIP-seq
MIRT2572487	hsa-miR-548a-5p	CLIP-seq
MIRT2572488	hsa-miR-548ab	CLIP-seq
MIRT2044518	hsa-miR-548ag	CLIP-seq
MIRT2044519	hsa-miR-548ai	CLIP-seq
MIRT2572489	hsa-miR-548ak	CLIP-seq
MIRT2572490	hsa-miR-548b-5p	CLIP-seq
MIRT2273720	hsa-miR-548c-3p	CLIP-seq
MIRT2572491	hsa-miR-548c-5p	CLIP-seq
MIRT2572492	hsa-miR-548d-5p	CLIP-seq
MIRT2572493	hsa-miR-548e	CLIP-seq
MIRT2572494	hsa-miR-548f	CLIP-seq
MIRT2572495	hsa-miR-548h	CLIP-seq
MIRT2572496	hsa-miR-548i	CLIP-seq
MIRT2572497	hsa-miR-548j	CLIP-seq
MIRT2044520	hsa-miR-548m	CLIP-seq
MIRT2572498	hsa-miR-548w	CLIP-seq
MIRT2572499	hsa-miR-548y	CLIP-seq
MIRT2572500	hsa-miR-559	CLIP-seq
MIRT1155454	hsa-miR-584	CLIP-seq
MIRT2572501	hsa-miR-628-5p	CLIP-seq
MIRT2572502	hsa-miR-649	CLIP-seq
MIRT2044521	hsa-miR-887	CLIP-seq
MIRT2572465	hsa-miR-1283	CLIP-seq
MIRT2572466	hsa-miR-23a	CLIP-seq
MIRT2572467	hsa-miR-23b	CLIP-seq
MIRT2572468	hsa-miR-23c	CLIP-seq
MIRT2572469	hsa-miR-2681	CLIP-seq
MIRT2572470	hsa-miR-3121-3p	CLIP-seq
MIRT2572471	hsa-miR-3148	CLIP-seq
MIRT2044512	hsa-miR-3613-3p	CLIP-seq
MIRT2044513	hsa-miR-3646	CLIP-seq
MIRT2044514	hsa-miR-3662	CLIP-seq
MIRT2572473	hsa-miR-3908	CLIP-seq
MIRT2572474	hsa-miR-3942-5p	CLIP-seq
MIRT2572476	hsa-miR-3978	CLIP-seq
MIRT2044515	hsa-miR-4477a	CLIP-seq
MIRT2044516	hsa-miR-4503	CLIP-seq
MIRT2044517	hsa-miR-4698	CLIP-seq
MIRT2572477	hsa-miR-4700-3p	CLIP-seq
MIRT2572478	hsa-miR-4703-5p	CLIP-seq
MIRT2572479	hsa-miR-4718	CLIP-seq
MIRT2273712	hsa-miR-4719	CLIP-seq
MIRT2572482	hsa-miR-4766-3p	CLIP-seq
MIRT2572483	hsa-miR-490-3p	CLIP-seq
MIRT1155451	hsa-miR-500a	CLIP-seq
MIRT2273715	hsa-miR-513a-3p	CLIP-seq
MIRT2273716	hsa-miR-513b	CLIP-seq
MIRT2572486	hsa-miR-548a-3p	CLIP-seq
MIRT2044518	hsa-miR-548ag	CLIP-seq
MIRT2044519	hsa-miR-548ai	CLIP-seq
MIRT2273720	hsa-miR-548c-3p	CLIP-seq
MIRT2572493	hsa-miR-548e	CLIP-seq
MIRT2572494	hsa-miR-548f	CLIP-seq
MIRT2044520	hsa-miR-548m	CLIP-seq
MIRT2572502	hsa-miR-649	CLIP-seq
MIRT2044521	hsa-miR-887	CLIP-seq

Show/Hide all (34)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	34759314
GO:0000785	Component	Chromatin	IDA	34759314
GO:0002376	Process	Immune system process	IEA
GO:0003677	Function	DNA binding	IDA	34759314
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	26496610, 27173435, 32296183, 33961781, 35271311, 35914814
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005694	Component	Chromosome	IEA
GO:0006325	Process	Chromatin organization	IEA
GO:0006468	Process	Protein phosphorylation	IDA	17332504
GO:0008270	Function	Zinc ion binding	IEA
GO:0009791	Process	Post-embryonic development	IEA
GO:0016363	Component	Nuclear matrix	IEA
GO:0016605	Component	PML body	IBA
GO:0016605	Component	PML body	IDA	27440897
GO:0016605	Component	PML body	IDA	17332504
GO:0016605	Component	PML body	IEA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0018105	Process	Peptidyl-serine phosphorylation	IDA	17332504
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	27440897
GO:0032688	Process	Negative regulation of interferon-beta production	IDA	34759314
GO:0045087	Process	Innate immune response	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048147	Process	Negative regulation of fibroblast proliferation	IDA	17332504
GO:0050821	Process	Protein stabilization	IDA	17332504
GO:0051457	Process	Maintenance of protein location in nucleus	IDA	17332504
GO:0051457	Process	Maintenance of protein location in nucleus	IMP	17332504
GO:0060337	Process	Type I interferon-mediated signaling pathway	IDA	18035482
GO:0140002	Function	Histone H3K4me3 reader activity	IDA	26933034
GO:0140374	Process	Antiviral innate immune response	IDA	27440897
GO:2000774	Process	Positive regulation of cellular senescence	IDA	17332504

MIM	HGNC	e!Ensembl
610078	23572	ENSG00000159256

Q14149

Protein name

MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3)

Protein function

Nuclear matrix protein which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism and plays a role in innate immunity by restricting different viruses through modulation of the IFN response (PubMed:27440897, PubMed:34759314). Mechanis

PDB

4QQ4 , 5SVI , 5SVX , 5SVY , 6O1E , 6O5W

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13589	HATPase_c_3	26 → 164		Domain
PF17942	Morc6_S5	249 → 382	Morc6 ribosomal protein S5 domain 2-like	Family
PF07496	zf-CW	409 → 452	CW-type Zinc Finger	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney. {ECO:0000269|PubMed:11927593}.

Sequence

MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDH
ICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTK
NGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQK
LLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERM
DQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVR
ITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQD
FDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR
KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPE
MIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS
LKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQ
SHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEID
VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMF
TDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEI
ERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELL
EMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVG
QLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST

Sequence length

939

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (25)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult type dermatomyositis	Dermatomyositis	BEFREE	28045754, 30639643, 31571350, 31779485, 31808188		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	28045754, 30850548		★★★★★ ★☆☆☆☆ Found in Text Mining only
Calcinosis	Calcinosis	Pubtator	24869801, 28129490, 38199847	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Deglutition Disorders	Dysphagia	BEFREE	28085235, 28129490, 30039266		★★★★★ ★☆☆☆☆ Found in Text Mining only
Deglutition Disorders	Deglutition disorder	Pubtator	28129490	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatologic disorders	Dermatologic Disorders	BEFREE	28129490		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatomyositis	Dermatomyositis	Pubtator	26028648, 28129490, 30915368, 32310254, 33305541, 34873015, 38199847	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatomyositis	Dermatomyositis	BEFREE	28045754, 30639643, 31571350, 31779485, 31808188		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatomyositis, Childhood Type	Dermatomyositis	BEFREE	29474663		★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down Syndrome	BEFREE	27653685		★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down syndrome	Pubtator	27653685	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Edema	Edema	Pubtator	28129490	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Exanthema	Exanthema	Pubtator	32310254	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastrointestinal Diseases	Gastrointestinal disease	Pubtator	38199847	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Idiopathic Inflammatory Myopathies	Inflammatory Myopathy	BEFREE	29178913, 29534337, 30445156		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	29995816		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Diseases Interstitial	Lung disease	Pubtator	26028648, 30915368, 38199847	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Diseases, Interstitial	Lung Diseases	BEFREE	30445156, 30616054, 30639643		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	27653685, 28085235, 28129490, 29178913, 30039266, 30445156, 30639643, 30850548		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopathy	Myopathy	BEFREE	30039266		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myositis	Myositis	BEFREE	27653685, 28871260, 30039266, 30639643, 31779485		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myositis	Myositis	Pubtator	27653685, 32310254	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myotonic Dystrophy	Myotonic dystrophy	Pubtator	38199847	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	30039266		★★★★★ ★☆☆☆☆ Found in Text Mining only
Skin Diseases	Skin disease	Pubtator	28129490	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

MORC3 (MORC family CW-type zinc finger 3)