RHOQ (ras homolog family member Q)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23433 |
| Gene name | Ras homolog family member Q |
| Gene symbol | RHOQ |
| Synonyms (NCBI Gene) |
ARHQHEL-S-42RASL7ATC10TC10A
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| Chromosome | 2 |
| Chromosome location | 2p21 |
| Summary | This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskel |
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miRNA
miRNA information provided by mirtarbase database.
489
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
40
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P17081 | ||||||||||
| Protein name | Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A) | ||||||||||
| Protein function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization pr | ||||||||||
| PDB | 2ATX | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 205 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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