VPS8 (VPS8 subunit of CORVET complex)

Gene

• Entrez ID: 23355
• Gene name: VPS8 subunit of CORVET complex
• Gene symbol: VPS8
• Synonyms (NCBI Gene): KIAA0804
• Chromosome: 3
• Chromosome location: 3q27.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018846	hsa-miR-335-5p	Microarray	18185580
MIRT714724	hsa-miR-6087	HITS-CLIP	19536157
MIRT714723	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT714722	hsa-miR-4757-5p	HITS-CLIP	19536157
MIRT714721	hsa-miR-6744-3p	HITS-CLIP	19536157
MIRT714720	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT714719	hsa-miR-663a	HITS-CLIP	19536157
MIRT714718	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT714717	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT714724	hsa-miR-6087	HITS-CLIP	19536157
MIRT714723	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT714722	hsa-miR-4757-5p	HITS-CLIP	19536157
MIRT714721	hsa-miR-6744-3p	HITS-CLIP	19536157
MIRT714720	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT714719	hsa-miR-663a	HITS-CLIP	19536157
MIRT714718	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT714717	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT711362	hsa-miR-6800-3p	HITS-CLIP	19536157
MIRT711361	hsa-miR-6728-3p	HITS-CLIP	19536157
MIRT711360	hsa-miR-9-5p	HITS-CLIP	19536157
MIRT711359	hsa-miR-3194-3p	HITS-CLIP	19536157
MIRT711358	hsa-miR-5691	HITS-CLIP	19536157
MIRT711357	hsa-miR-6805-3p	HITS-CLIP	19536157
MIRT672363	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT672362	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT672361	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT672360	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT672359	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT672358	hsa-miR-4284	HITS-CLIP	23824327
MIRT672357	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT518431	hsa-miR-7977	HITS-CLIP	23824327
MIRT672356	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT672355	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT672354	hsa-miR-588	HITS-CLIP	23824327
MIRT672353	hsa-miR-4435	HITS-CLIP	23824327
MIRT672352	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT672351	hsa-miR-651-5p	HITS-CLIP	23824327
MIRT672350	hsa-miR-7159-3p	HITS-CLIP	23824327
MIRT672349	hsa-miR-4482-3p	HITS-CLIP	23824327
MIRT664545	hsa-miR-6771-3p	HITS-CLIP	23824327
MIRT664544	hsa-miR-3675-3p	HITS-CLIP	23824327
MIRT664543	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT664542	hsa-miR-4786-5p	HITS-CLIP	23824327
MIRT664541	hsa-miR-4684-5p	HITS-CLIP	23824327
MIRT648801	hsa-miR-4418	HITS-CLIP	23824327
MIRT648800	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT648799	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT648798	hsa-miR-217	HITS-CLIP	23824327
MIRT648797	hsa-miR-6807-3p	HITS-CLIP	23824327
MIRT648796	hsa-miR-1208	HITS-CLIP	23824327
MIRT648795	hsa-miR-1184	HITS-CLIP	23824327
MIRT648794	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT648793	hsa-miR-5189-3p	HITS-CLIP	23824327
MIRT648792	hsa-miR-3926	HITS-CLIP	23824327
MIRT648791	hsa-miR-642b-5p	HITS-CLIP	23824327
MIRT648790	hsa-miR-7156-3p	HITS-CLIP	23824327
MIRT648789	hsa-miR-548s	HITS-CLIP	23824327
MIRT570078	hsa-miR-6858-3p	PAR-CLIP	20371350
MIRT570077	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT570076	hsa-miR-665	PAR-CLIP	20371350
MIRT570075	hsa-miR-6761-5p	PAR-CLIP	20371350
MIRT570074	hsa-miR-769-5p	PAR-CLIP	20371350
MIRT570073	hsa-miR-3194-5p	PAR-CLIP	20371350
MIRT518439	hsa-miR-541-3p	PAR-CLIP	23446348
MIRT518438	hsa-miR-654-5p	PAR-CLIP	23446348
MIRT518437	hsa-miR-92a-2-5p	PAR-CLIP	23446348
MIRT518435	hsa-miR-6769a-5p	PAR-CLIP	23446348
MIRT518436	hsa-miR-6769b-5p	PAR-CLIP	23446348
MIRT518434	hsa-miR-323a-5p	PAR-CLIP	23446348
MIRT518433	hsa-miR-876-3p	PAR-CLIP	23446348
MIRT518432	hsa-miR-6748-5p	PAR-CLIP	23446348
MIRT518431	hsa-miR-7977	PAR-CLIP	23446348
MIRT518430	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT714724	hsa-miR-6087	HITS-CLIP	19536157
MIRT714723	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT714722	hsa-miR-4757-5p	HITS-CLIP	19536157
MIRT714721	hsa-miR-6744-3p	HITS-CLIP	19536157
MIRT714720	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT714719	hsa-miR-663a	HITS-CLIP	19536157
MIRT714718	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT714717	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT714724	hsa-miR-6087	HITS-CLIP	19536157
MIRT714723	hsa-miR-744-5p	HITS-CLIP	19536157
MIRT714722	hsa-miR-4757-5p	HITS-CLIP	19536157
MIRT714721	hsa-miR-6744-3p	HITS-CLIP	19536157
MIRT714720	hsa-miR-1908-5p	HITS-CLIP	19536157
MIRT714719	hsa-miR-663a	HITS-CLIP	19536157
MIRT714718	hsa-miR-6787-5p	HITS-CLIP	19536157
MIRT714717	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT711362	hsa-miR-6800-3p	HITS-CLIP	19536157
MIRT711361	hsa-miR-6728-3p	HITS-CLIP	19536157
MIRT711360	hsa-miR-9-5p	HITS-CLIP	19536157
MIRT711359	hsa-miR-3194-3p	HITS-CLIP	19536157
MIRT711358	hsa-miR-5691	HITS-CLIP	19536157
MIRT711357	hsa-miR-6805-3p	HITS-CLIP	19536157
MIRT672363	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT672362	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT672361	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT672360	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT672359	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT672358	hsa-miR-4284	HITS-CLIP	23824327
MIRT672357	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT518431	hsa-miR-7977	HITS-CLIP	23824327
MIRT672356	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT672355	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT672354	hsa-miR-588	HITS-CLIP	23824327
MIRT672353	hsa-miR-4435	HITS-CLIP	23824327
MIRT672352	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT672351	hsa-miR-651-5p	HITS-CLIP	23824327
MIRT672350	hsa-miR-7159-3p	HITS-CLIP	23824327
MIRT672349	hsa-miR-4482-3p	HITS-CLIP	23824327
MIRT664545	hsa-miR-6771-3p	HITS-CLIP	23824327
MIRT664544	hsa-miR-3675-3p	HITS-CLIP	23824327
MIRT664543	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT664542	hsa-miR-4786-5p	HITS-CLIP	23824327
MIRT664541	hsa-miR-4684-5p	HITS-CLIP	23824327
MIRT648801	hsa-miR-4418	HITS-CLIP	23824327
MIRT648800	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT648799	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT648798	hsa-miR-217	HITS-CLIP	23824327
MIRT648797	hsa-miR-6807-3p	HITS-CLIP	23824327
MIRT648796	hsa-miR-1208	HITS-CLIP	23824327
MIRT648795	hsa-miR-1184	HITS-CLIP	23824327
MIRT648794	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT648793	hsa-miR-5189-3p	HITS-CLIP	23824327
MIRT648792	hsa-miR-3926	HITS-CLIP	23824327
MIRT648791	hsa-miR-642b-5p	HITS-CLIP	23824327
MIRT648790	hsa-miR-7156-3p	HITS-CLIP	23824327
MIRT648789	hsa-miR-548s	HITS-CLIP	23824327
MIRT570078	hsa-miR-6858-3p	PAR-CLIP	20371350
MIRT570077	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT570076	hsa-miR-665	PAR-CLIP	20371350
MIRT570075	hsa-miR-6761-5p	PAR-CLIP	20371350
MIRT570074	hsa-miR-769-5p	PAR-CLIP	20371350
MIRT570073	hsa-miR-3194-5p	PAR-CLIP	20371350
MIRT518439	hsa-miR-541-3p	PAR-CLIP	23446348
MIRT518438	hsa-miR-654-5p	PAR-CLIP	23446348
MIRT518437	hsa-miR-92a-2-5p	PAR-CLIP	23446348
MIRT518435	hsa-miR-6769a-5p	PAR-CLIP	23446348
MIRT518436	hsa-miR-6769b-5p	PAR-CLIP	23446348
MIRT518434	hsa-miR-323a-5p	PAR-CLIP	23446348
MIRT518433	hsa-miR-876-3p	PAR-CLIP	23446348
MIRT518432	hsa-miR-6748-5p	PAR-CLIP	23446348
MIRT518431	hsa-miR-7977	PAR-CLIP	23446348
MIRT518430	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT1487415	hsa-miR-1	CLIP-seq
MIRT1487416	hsa-miR-1207-3p	CLIP-seq
MIRT1487417	hsa-miR-1273f	CLIP-seq
MIRT1487418	hsa-miR-128	CLIP-seq
MIRT1487419	hsa-miR-1291	CLIP-seq
MIRT1487420	hsa-miR-1299	CLIP-seq
MIRT1487421	hsa-miR-147	CLIP-seq
MIRT1487422	hsa-miR-183	CLIP-seq
MIRT1487423	hsa-miR-202	CLIP-seq
MIRT1487424	hsa-miR-206	CLIP-seq
MIRT1487425	hsa-miR-22	CLIP-seq
MIRT1487426	hsa-miR-3135b	CLIP-seq
MIRT1487427	hsa-miR-3143	CLIP-seq
MIRT1487428	hsa-miR-3148	CLIP-seq
MIRT1487429	hsa-miR-3150b-3p	CLIP-seq
MIRT1487430	hsa-miR-320a	CLIP-seq
MIRT1487431	hsa-miR-320b	CLIP-seq
MIRT1487432	hsa-miR-320c	CLIP-seq
MIRT1487433	hsa-miR-320d	CLIP-seq
MIRT1487434	hsa-miR-320e	CLIP-seq
MIRT1487435	hsa-miR-328	CLIP-seq
MIRT1487436	hsa-miR-338-3p	CLIP-seq
MIRT1487437	hsa-miR-346	CLIP-seq
MIRT1487438	hsa-miR-3671	CLIP-seq
MIRT1487439	hsa-miR-3673	CLIP-seq
MIRT1487440	hsa-miR-3685	CLIP-seq
MIRT1487441	hsa-miR-3688-3p	CLIP-seq
MIRT1487442	hsa-miR-384	CLIP-seq
MIRT1487443	hsa-miR-3910	CLIP-seq
MIRT1487444	hsa-miR-3977	CLIP-seq
MIRT1487445	hsa-miR-4257	CLIP-seq
MIRT1487446	hsa-miR-4288	CLIP-seq
MIRT1487447	hsa-miR-4429	CLIP-seq
MIRT1487448	hsa-miR-4464	CLIP-seq
MIRT1487449	hsa-miR-4501	CLIP-seq
MIRT1487450	hsa-miR-4504	CLIP-seq
MIRT1487451	hsa-miR-4520a-3p	CLIP-seq
MIRT1487452	hsa-miR-4522	CLIP-seq
MIRT1487453	hsa-miR-4530	CLIP-seq
MIRT1487454	hsa-miR-4638-3p	CLIP-seq
MIRT1487455	hsa-miR-4748	CLIP-seq
MIRT1487456	hsa-miR-4771	CLIP-seq
MIRT1487457	hsa-miR-4784	CLIP-seq
MIRT1487458	hsa-miR-515-5p	CLIP-seq
MIRT1487459	hsa-miR-542-3p	CLIP-seq
MIRT1487460	hsa-miR-599	CLIP-seq
MIRT1487461	hsa-miR-613	CLIP-seq
MIRT1487462	hsa-miR-632	CLIP-seq
MIRT1487463	hsa-miR-646	CLIP-seq
MIRT1487464	hsa-miR-765	CLIP-seq
MIRT1487465	hsa-miR-767-3p	CLIP-seq
MIRT1487466	hsa-miR-875-3p	CLIP-seq
MIRT1487467	hsa-miR-888	CLIP-seq
MIRT1487468	hsa-miR-935	CLIP-seq
MIRT1487469	hsa-miR-1253	CLIP-seq
MIRT1487470	hsa-miR-2277-3p	CLIP-seq
MIRT1487471	hsa-miR-3120-3p	CLIP-seq
MIRT1487472	hsa-miR-3192	CLIP-seq
MIRT1487473	hsa-miR-3618	CLIP-seq
MIRT1487474	hsa-miR-3907	CLIP-seq
MIRT1487475	hsa-miR-3908	CLIP-seq
MIRT1487476	hsa-miR-4294	CLIP-seq
MIRT1487477	hsa-miR-4434	CLIP-seq
MIRT1487478	hsa-miR-4463	CLIP-seq
MIRT1487479	hsa-miR-4491	CLIP-seq
MIRT1487480	hsa-miR-4516	CLIP-seq
MIRT1487481	hsa-miR-4531	CLIP-seq
MIRT1487482	hsa-miR-4646-5p	CLIP-seq
MIRT1487483	hsa-miR-4657	CLIP-seq
MIRT1487484	hsa-miR-4790-3p	CLIP-seq
MIRT1487470	hsa-miR-2277-3p	CLIP-seq
MIRT1487471	hsa-miR-3120-3p	CLIP-seq
MIRT1487475	hsa-miR-3908	CLIP-seq
MIRT1487479	hsa-miR-4491	CLIP-seq
MIRT1487483	hsa-miR-4657	CLIP-seq
MIRT1487469	hsa-miR-1253	CLIP-seq
MIRT1487472	hsa-miR-3192	CLIP-seq
MIRT1487473	hsa-miR-3618	CLIP-seq
MIRT1487474	hsa-miR-3907	CLIP-seq
MIRT1487476	hsa-miR-4294	CLIP-seq
MIRT1487477	hsa-miR-4434	CLIP-seq
MIRT1487478	hsa-miR-4463	CLIP-seq
MIRT1487480	hsa-miR-4516	CLIP-seq
MIRT1487481	hsa-miR-4531	CLIP-seq
MIRT1487482	hsa-miR-4646-5p	CLIP-seq
MIRT1487484	hsa-miR-4790-3p	CLIP-seq
MIRT1487469	hsa-miR-1253	CLIP-seq
MIRT1487417	hsa-miR-1273f	CLIP-seq
MIRT1487418	hsa-miR-128	CLIP-seq
MIRT2660760	hsa-miR-1285	CLIP-seq
MIRT1487419	hsa-miR-1291	CLIP-seq
MIRT1487470	hsa-miR-2277-3p	CLIP-seq
MIRT1487471	hsa-miR-3120-3p	CLIP-seq
MIRT2660761	hsa-miR-3138	CLIP-seq
MIRT1487427	hsa-miR-3143	CLIP-seq
MIRT2660762	hsa-miR-3165	CLIP-seq
MIRT2660763	hsa-miR-3187-5p	CLIP-seq
MIRT1487472	hsa-miR-3192	CLIP-seq
MIRT2660764	hsa-miR-326	CLIP-seq
MIRT1487435	hsa-miR-328	CLIP-seq
MIRT2660765	hsa-miR-330-5p	CLIP-seq
MIRT1487437	hsa-miR-346	CLIP-seq
MIRT2660766	hsa-miR-3612	CLIP-seq
MIRT1487473	hsa-miR-3618	CLIP-seq
MIRT1487438	hsa-miR-3671	CLIP-seq
MIRT2660767	hsa-miR-3689a-3p	CLIP-seq
MIRT2660768	hsa-miR-3689c	CLIP-seq
MIRT2660769	hsa-miR-3689d	CLIP-seq
MIRT2660770	hsa-miR-378g	CLIP-seq
MIRT1487474	hsa-miR-3907	CLIP-seq
MIRT1487475	hsa-miR-3908	CLIP-seq
MIRT1487443	hsa-miR-3910	CLIP-seq
MIRT1487446	hsa-miR-4288	CLIP-seq
MIRT1487476	hsa-miR-4294	CLIP-seq
MIRT2660771	hsa-miR-4330	CLIP-seq
MIRT1487477	hsa-miR-4434	CLIP-seq
MIRT2660772	hsa-miR-4443	CLIP-seq
MIRT1487478	hsa-miR-4463	CLIP-seq
MIRT1487448	hsa-miR-4464	CLIP-seq
MIRT2660773	hsa-miR-4486	CLIP-seq
MIRT1487479	hsa-miR-4491	CLIP-seq
MIRT1487480	hsa-miR-4516	CLIP-seq
MIRT1487481	hsa-miR-4531	CLIP-seq
MIRT1487482	hsa-miR-4646-5p	CLIP-seq
MIRT1487483	hsa-miR-4657	CLIP-seq
MIRT2660774	hsa-miR-4728-5p	CLIP-seq
MIRT1487455	hsa-miR-4748	CLIP-seq
MIRT1487484	hsa-miR-4790-3p	CLIP-seq
MIRT2660775	hsa-miR-4800-5p	CLIP-seq
MIRT1487458	hsa-miR-515-5p	CLIP-seq
MIRT2660776	hsa-miR-612	CLIP-seq
MIRT1487462	hsa-miR-632	CLIP-seq
MIRT2660777	hsa-miR-650	CLIP-seq
MIRT1487465	hsa-miR-767-3p	CLIP-seq
MIRT1487467	hsa-miR-888	CLIP-seq
MIRT2660778	hsa-miR-942	CLIP-seq
MIRT1487469	hsa-miR-1253	CLIP-seq
MIRT1487417	hsa-miR-1273f	CLIP-seq
MIRT1487418	hsa-miR-128	CLIP-seq
MIRT2660760	hsa-miR-1285	CLIP-seq
MIRT1487419	hsa-miR-1291	CLIP-seq
MIRT1487470	hsa-miR-2277-3p	CLIP-seq
MIRT1487471	hsa-miR-3120-3p	CLIP-seq
MIRT2660761	hsa-miR-3138	CLIP-seq
MIRT1487427	hsa-miR-3143	CLIP-seq
MIRT2660763	hsa-miR-3187-5p	CLIP-seq
MIRT1487472	hsa-miR-3192	CLIP-seq
MIRT2660764	hsa-miR-326	CLIP-seq
MIRT1487435	hsa-miR-328	CLIP-seq
MIRT2660765	hsa-miR-330-5p	CLIP-seq
MIRT1487437	hsa-miR-346	CLIP-seq
MIRT1487473	hsa-miR-3618	CLIP-seq
MIRT1487438	hsa-miR-3671	CLIP-seq
MIRT2660767	hsa-miR-3689a-3p	CLIP-seq
MIRT2660768	hsa-miR-3689c	CLIP-seq
MIRT2660769	hsa-miR-3689d	CLIP-seq
MIRT2660770	hsa-miR-378g	CLIP-seq
MIRT1487474	hsa-miR-3907	CLIP-seq
MIRT1487475	hsa-miR-3908	CLIP-seq
MIRT1487443	hsa-miR-3910	CLIP-seq
MIRT1487444	hsa-miR-3977	CLIP-seq
MIRT1487446	hsa-miR-4288	CLIP-seq
MIRT1487476	hsa-miR-4294	CLIP-seq
MIRT2660771	hsa-miR-4330	CLIP-seq
MIRT1487477	hsa-miR-4434	CLIP-seq
MIRT1487478	hsa-miR-4463	CLIP-seq
MIRT1487448	hsa-miR-4464	CLIP-seq
MIRT2660773	hsa-miR-4486	CLIP-seq
MIRT1487479	hsa-miR-4491	CLIP-seq
MIRT1487480	hsa-miR-4516	CLIP-seq
MIRT1487481	hsa-miR-4531	CLIP-seq
MIRT1487482	hsa-miR-4646-5p	CLIP-seq
MIRT1487483	hsa-miR-4657	CLIP-seq
MIRT2660774	hsa-miR-4728-5p	CLIP-seq
MIRT1487455	hsa-miR-4748	CLIP-seq
MIRT1487484	hsa-miR-4790-3p	CLIP-seq
MIRT2660775	hsa-miR-4800-5p	CLIP-seq
MIRT1487458	hsa-miR-515-5p	CLIP-seq
MIRT2660776	hsa-miR-612	CLIP-seq
MIRT1487462	hsa-miR-632	CLIP-seq
MIRT1487465	hsa-miR-767-3p	CLIP-seq
MIRT1487467	hsa-miR-888	CLIP-seq
MIRT1487468	hsa-miR-935	CLIP-seq
MIRT2660778	hsa-miR-942	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25266290, 33961781, 35271311
GO:0005768	Component	Endosome	IEA
GO:0005769	Component	Early endosome	IBA
GO:0005769	Component	Early endosome	IDA	25266290
GO:0005769	Component	Early endosome	IEA
GO:0005770	Component	Late endosome	IBA
GO:0006623	Process	Protein targeting to vacuole	IBA
GO:0006623	Process	Protein targeting to vacuole	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0015031	Process	Protein transport	IEA
GO:0030897	Component	HOPS complex	IBA
GO:0033263	Component	CORVET complex	IBA
GO:0033263	Component	CORVET complex	IEA
GO:0033263	Component	CORVET complex	NAS	31092635
GO:0034058	Process	Endosomal vesicle fusion	IBA
GO:0034058	Process	Endosomal vesicle fusion	IMP	25266290
GO:0034058	Process	Endosomal vesicle fusion	NAS	31092635
GO:0035542	Process	Regulation of SNARE complex assembly	NAS	31092635
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 618366
• HGNC: 29122
• e!Ensembl: ENSG00000156931

Protein

• UniProt ID: Q8N3P4
• Protein name: Vacuolar protein sorting-associated protein 8 homolog
• Protein function: Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome c
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12816	Vps8	614 → 796	Golgi CORVET complex core vacuolar protein 8	Domain

• Sequence:

  MENEPDHENVEQSLCAKTSEEELNKSFNLEASLSKFSYIDMDKELEFKNDLIDDKEFDIP
  QVDTPPTLESILNETDDEDESFILEDPTLLNIDTIDSHSYDTSSVASSDSGDRTNLKRKK
  KLPDSFSLHGSVMRHSLLKGISAQIVSAADKVDAGLPTAIAVSSLIAVGTSHGLALIFGK
  DQNQALRLCLGSTSVGGQYGAISALSINNDCSRLLCGFAKGQITMWDLASGKLLRSITDA
  HPPGTAILHIKFTDDPTLAICNDSGGSVFELTFKRVMGVRTCESRCLFSGSKGEVCCIEP
  LHSKPELKDHPITQFSLLAMASLTKILVIGLKPSLKVWMTFPYGRMDPSSVPLLAWHFVA
  VQNYVNPMLAFCRGDVVHFLLVKRDESGAIHVTKQKHLHLYYDLINFTWINSRTVVLLDS
  VEKLHVIDRQTQEELETVEISEVQLVYNSSHFKSLATGGNVSQALALVGEKACYQSISSY
  GGQIFYLGTKSVYVMMLRSWRERVDHLLKQDCLTEALALAWSFHEGKAKAVVGLSGDASK
  RKAIVADRMVEILFHYADRALKKCPDQGKIQVMEQHFQDMVPVIVDYCLLLQRKDLLFSQ
  MYDKLSENSVAKGVFLECLEPYILSDKLVGITPQVMKDLIVHFQDKKLMENVEALIVHMD
  ITSLDIQQVVLMCWENRLYDAMIYVYNRGMNEFISPMEKLFRVIAPPLNAGKTLTDEQVV
  MGNKLLVYISCCLAGRAYPLGDIPEDLVPLVKNQVFEFLIRLHSAEASPEEEIYPYIRTL
  LHFDTREFLNVLALTFEDFKNDKQAVEYQQRIVDILLKVMVENSDFTPSQVGCLFTFLAR
  QLAKPDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIRMA
  EKAEFYQICEFMYEREHQYDKIIDCYLRDPLREEEVFNYIHNILSIPGHSAEEKQSVWQK
  AMDHIEELVSLKPCKAAELVATHFSGHIETVIKKLQNQVLLFKFLRSLLDPREGIHVNQE
  LLQISPCITEQFIELLCQFNPTQVIETLQVLECYRLEETIQITQKYQLHEVTAYLLEKKG
  DIHGAFLIMLERLQSKLQEVTHQGENTKEDPSLKDVEDTMVETIALCQRNSHNLNQQQRE
  ALWFPLLEAMMAPQKLSSSAIPHLHSEALKSLTMQVLNSMAAFIALPSILQRILQDPVYG
  KGKLGEIQGLILGMLDTFNYEQTLLETTTSLLNQDLHWSLCNLRASVTRGLNPKQDYCSI
  CLQQYKRRQEMADEIIVFSCGHLYHSFCLQNKECTVEFEGQTRWTCYKCSSSNKVGKLSE
  NSSEIKKGRITPSQVKMSPSYHQSKGDPTAKKGTSEPVLDPQQIQAFDQLCRLYRGSSRL
  ALLTELSQNRSSESYRPFSGSQSAPAFNSIFQNENFQLQLIPPPVTED

• Sequence length: 1428

Pathways

KEGG:

Efferocytosis

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ARTHROGRYPOSIS MULTIPLEX CONGENITA	—	ClinGen, Disgenet, GenCC ClinGen, Disgenet, GenCC	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Flexion contracture	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VPS8-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Arthrogryposis	Arthrogryposis multiplex congenita	GENOMICS_ENGLAND_DG	23840658		★☆☆☆☆ Found in Text Mining only
Arthrogryposis	Arthrogryposis multiplex congenita	CLINGEN_DG	23840658, 26752647, 8969229		★☆☆☆☆ Found in Text Mining only
Arthrogryposis	Arthrogryposis	Pubtator	26752647	Associate	★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognition disorder	Pubtator	40494419	Associate	★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial infarction	Pubtator	36553589	Associate	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	40494419	Associate	★☆☆☆☆ Found in Text Mining only