Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	23303
Gene name	Kinesin family member 13B
Gene symbol	KIF13B
Synonyms (NCBI Gene)	GAKIN
Chromosome	8
Chromosome location	8p12

206

Show/Hide all (206)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018370	hsa-miR-335-5p	Microarray	18185580
MIRT1093259	hsa-miR-1182	CLIP-seq
MIRT1093260	hsa-miR-1207-5p	CLIP-seq
MIRT1093261	hsa-miR-1226	CLIP-seq
MIRT1093262	hsa-miR-1237	CLIP-seq
MIRT1093263	hsa-miR-1285	CLIP-seq
MIRT1093264	hsa-miR-1294	CLIP-seq
MIRT1093265	hsa-miR-1297	CLIP-seq
MIRT1093266	hsa-miR-1321	CLIP-seq
MIRT1093267	hsa-miR-146b-3p	CLIP-seq
MIRT1093268	hsa-miR-1538	CLIP-seq
MIRT1093269	hsa-miR-181a	CLIP-seq
MIRT1093270	hsa-miR-181b	CLIP-seq
MIRT1093271	hsa-miR-181c	CLIP-seq
MIRT1093272	hsa-miR-181d	CLIP-seq
MIRT1093273	hsa-miR-1915	CLIP-seq
MIRT1093274	hsa-miR-2114	CLIP-seq
MIRT1093275	hsa-miR-26a	CLIP-seq
MIRT1093276	hsa-miR-26b	CLIP-seq
MIRT1093277	hsa-miR-3123	CLIP-seq
MIRT1093278	hsa-miR-3150a-3p	CLIP-seq
MIRT1093279	hsa-miR-3175	CLIP-seq
MIRT1093280	hsa-miR-3179	CLIP-seq
MIRT1093281	hsa-miR-3182	CLIP-seq
MIRT1093282	hsa-miR-3187-5p	CLIP-seq
MIRT1093283	hsa-miR-324-5p	CLIP-seq
MIRT1093284	hsa-miR-3611	CLIP-seq
MIRT1093285	hsa-miR-361-3p	CLIP-seq
MIRT1093286	hsa-miR-3614-3p	CLIP-seq
MIRT1093287	hsa-miR-371b-5p	CLIP-seq
MIRT1093288	hsa-miR-378g	CLIP-seq
MIRT1093289	hsa-miR-3925-5p	CLIP-seq
MIRT1093290	hsa-miR-4262	CLIP-seq
MIRT1093291	hsa-miR-4270	CLIP-seq
MIRT1093292	hsa-miR-4283	CLIP-seq
MIRT1093293	hsa-miR-4284	CLIP-seq
MIRT1093294	hsa-miR-4314	CLIP-seq
MIRT1093295	hsa-miR-4316	CLIP-seq
MIRT1093296	hsa-miR-4437	CLIP-seq
MIRT1093297	hsa-miR-4441	CLIP-seq
MIRT1093298	hsa-miR-4465	CLIP-seq
MIRT1093299	hsa-miR-4470	CLIP-seq
MIRT1093300	hsa-miR-4486	CLIP-seq
MIRT1093301	hsa-miR-4506	CLIP-seq
MIRT1093302	hsa-miR-4508	CLIP-seq
MIRT1093303	hsa-miR-4532	CLIP-seq
MIRT1093304	hsa-miR-4677-3p	CLIP-seq
MIRT1093305	hsa-miR-4679	CLIP-seq
MIRT1093306	hsa-miR-4733-3p	CLIP-seq
MIRT1093307	hsa-miR-4734	CLIP-seq
MIRT1093308	hsa-miR-4736	CLIP-seq
MIRT1093309	hsa-miR-4739	CLIP-seq
MIRT1093310	hsa-miR-4745-3p	CLIP-seq
MIRT1093311	hsa-miR-4756-5p	CLIP-seq
MIRT1093312	hsa-miR-4763-3p	CLIP-seq
MIRT1093313	hsa-miR-4781-5p	CLIP-seq
MIRT1093314	hsa-miR-4803	CLIP-seq
MIRT1093315	hsa-miR-516b	CLIP-seq
MIRT1093316	hsa-miR-548al	CLIP-seq
MIRT1093317	hsa-miR-553	CLIP-seq
MIRT1093318	hsa-miR-566	CLIP-seq
MIRT1093319	hsa-miR-604	CLIP-seq
MIRT1093320	hsa-miR-612	CLIP-seq
MIRT1093321	hsa-miR-615-5p	CLIP-seq
MIRT1093322	hsa-miR-635	CLIP-seq
MIRT1093323	hsa-miR-647	CLIP-seq
MIRT1093324	hsa-miR-668	CLIP-seq
MIRT1093325	hsa-miR-744	CLIP-seq
MIRT1093326	hsa-miR-939	CLIP-seq
MIRT1093261	hsa-miR-1226	CLIP-seq
MIRT1093266	hsa-miR-1321	CLIP-seq
MIRT1093273	hsa-miR-1915	CLIP-seq
MIRT1093291	hsa-miR-4270	CLIP-seq
MIRT1093297	hsa-miR-4441	CLIP-seq
MIRT1093306	hsa-miR-4733-3p	CLIP-seq
MIRT1093309	hsa-miR-4739	CLIP-seq
MIRT1093311	hsa-miR-4756-5p	CLIP-seq
MIRT1093261	hsa-miR-1226	CLIP-seq
MIRT2025005	hsa-miR-124	CLIP-seq
MIRT2025006	hsa-miR-1266	CLIP-seq
MIRT2025007	hsa-miR-1908	CLIP-seq
MIRT2025008	hsa-miR-224	CLIP-seq
MIRT2025009	hsa-miR-3124-3p	CLIP-seq
MIRT2025010	hsa-miR-3150b-3p	CLIP-seq
MIRT1093285	hsa-miR-361-3p	CLIP-seq
MIRT2025011	hsa-miR-3664-3p	CLIP-seq
MIRT2025012	hsa-miR-3689a-3p	CLIP-seq
MIRT2025013	hsa-miR-3689c	CLIP-seq
MIRT2025014	hsa-miR-3973	CLIP-seq
MIRT2025015	hsa-miR-4436a	CLIP-seq
MIRT2025016	hsa-miR-4501	CLIP-seq
MIRT2025017	hsa-miR-4505	CLIP-seq
MIRT2025018	hsa-miR-4518	CLIP-seq
MIRT2025019	hsa-miR-4639-3p	CLIP-seq
MIRT2025020	hsa-miR-4689	CLIP-seq
MIRT2025021	hsa-miR-4691-3p	CLIP-seq
MIRT2025022	hsa-miR-4728-5p	CLIP-seq
MIRT2025023	hsa-miR-4731-5p	CLIP-seq
MIRT1093307	hsa-miR-4734	CLIP-seq
MIRT2025024	hsa-miR-4755-3p	CLIP-seq
MIRT2025025	hsa-miR-4767	CLIP-seq
MIRT2025026	hsa-miR-4784	CLIP-seq
MIRT2025027	hsa-miR-4789-3p	CLIP-seq
MIRT2025028	hsa-miR-485-5p	CLIP-seq
MIRT2025029	hsa-miR-506	CLIP-seq
MIRT2025030	hsa-miR-520g	CLIP-seq
MIRT2025031	hsa-miR-520h	CLIP-seq
MIRT2025032	hsa-miR-603	CLIP-seq
MIRT1093321	hsa-miR-615-5p	CLIP-seq
MIRT2025033	hsa-miR-642a	CLIP-seq
MIRT2025034	hsa-miR-663	CLIP-seq
MIRT1093261	hsa-miR-1226	CLIP-seq
MIRT2256113	hsa-miR-1228	CLIP-seq
MIRT2025005	hsa-miR-124	CLIP-seq
MIRT2025006	hsa-miR-1266	CLIP-seq
MIRT1093267	hsa-miR-146b-3p	CLIP-seq
MIRT2256114	hsa-miR-1913	CLIP-seq
MIRT1093273	hsa-miR-1915	CLIP-seq
MIRT2256115	hsa-miR-23a	CLIP-seq
MIRT2256116	hsa-miR-23b	CLIP-seq
MIRT2256117	hsa-miR-23c	CLIP-seq
MIRT2256118	hsa-miR-296-5p	CLIP-seq
MIRT2256119	hsa-miR-3127-5p	CLIP-seq
MIRT2256120	hsa-miR-3130-5p	CLIP-seq
MIRT2025010	hsa-miR-3150b-3p	CLIP-seq
MIRT1093280	hsa-miR-3179	CLIP-seq
MIRT2256121	hsa-miR-324-3p	CLIP-seq
MIRT2256122	hsa-miR-329	CLIP-seq
MIRT2256123	hsa-miR-339-5p	CLIP-seq
MIRT2256124	hsa-miR-3612	CLIP-seq
MIRT1093285	hsa-miR-361-3p	CLIP-seq
MIRT1093286	hsa-miR-3614-3p	CLIP-seq
MIRT2256125	hsa-miR-3622a-3p	CLIP-seq
MIRT2256126	hsa-miR-3622b-3p	CLIP-seq
MIRT2256127	hsa-miR-362-3p	CLIP-seq
MIRT2256128	hsa-miR-3679-3p	CLIP-seq
MIRT2256129	hsa-miR-3714	CLIP-seq
MIRT2256130	hsa-miR-377	CLIP-seq
MIRT2256131	hsa-miR-3918	CLIP-seq
MIRT1093292	hsa-miR-4283	CLIP-seq
MIRT2256132	hsa-miR-4313	CLIP-seq
MIRT2256133	hsa-miR-4482	CLIP-seq
MIRT1093301	hsa-miR-4506	CLIP-seq
MIRT2025018	hsa-miR-4518	CLIP-seq
MIRT2256134	hsa-miR-451b	CLIP-seq
MIRT2256135	hsa-miR-4523	CLIP-seq
MIRT2256136	hsa-miR-4667-5p	CLIP-seq
MIRT2256137	hsa-miR-4685-5p	CLIP-seq
MIRT2025020	hsa-miR-4689	CLIP-seq
MIRT2256138	hsa-miR-4695-5p	CLIP-seq
MIRT2256139	hsa-miR-4700-5p	CLIP-seq
MIRT2256140	hsa-miR-4704-3p	CLIP-seq
MIRT1093306	hsa-miR-4733-3p	CLIP-seq
MIRT2025026	hsa-miR-4784	CLIP-seq
MIRT2025029	hsa-miR-506	CLIP-seq
MIRT1093315	hsa-miR-516b	CLIP-seq
MIRT2256141	hsa-miR-544b	CLIP-seq
MIRT2256142	hsa-miR-552	CLIP-seq
MIRT1093321	hsa-miR-615-5p	CLIP-seq
MIRT2256143	hsa-miR-650	CLIP-seq
MIRT2256144	hsa-miR-764	CLIP-seq
MIRT2389847	hsa-miR-1247	CLIP-seq
MIRT2256114	hsa-miR-1913	CLIP-seq
MIRT2389848	hsa-miR-302a	CLIP-seq
MIRT2389849	hsa-miR-302b	CLIP-seq
MIRT2389850	hsa-miR-302c	CLIP-seq
MIRT2389851	hsa-miR-302d	CLIP-seq
MIRT2389852	hsa-miR-302e	CLIP-seq
MIRT2256121	hsa-miR-324-3p	CLIP-seq
MIRT1093285	hsa-miR-361-3p	CLIP-seq
MIRT2389853	hsa-miR-372	CLIP-seq
MIRT2389854	hsa-miR-373	CLIP-seq
MIRT2389855	hsa-miR-4290	CLIP-seq
MIRT2389856	hsa-miR-520a-3p	CLIP-seq
MIRT2389857	hsa-miR-520b	CLIP-seq
MIRT2389858	hsa-miR-520c-3p	CLIP-seq
MIRT2389859	hsa-miR-520d-3p	CLIP-seq
MIRT2389860	hsa-miR-520e	CLIP-seq
MIRT1093321	hsa-miR-615-5p	CLIP-seq
MIRT1093261	hsa-miR-1226	CLIP-seq
MIRT1093266	hsa-miR-1321	CLIP-seq
MIRT1093267	hsa-miR-146b-3p	CLIP-seq
MIRT1093273	hsa-miR-1915	CLIP-seq
MIRT1093291	hsa-miR-4270	CLIP-seq
MIRT1093297	hsa-miR-4441	CLIP-seq
MIRT1093306	hsa-miR-4733-3p	CLIP-seq
MIRT1093309	hsa-miR-4739	CLIP-seq
MIRT1093311	hsa-miR-4756-5p	CLIP-seq
MIRT1093261	hsa-miR-1226	CLIP-seq
MIRT1093266	hsa-miR-1321	CLIP-seq
MIRT1093267	hsa-miR-146b-3p	CLIP-seq
MIRT1093273	hsa-miR-1915	CLIP-seq
MIRT1093291	hsa-miR-4270	CLIP-seq
MIRT1093297	hsa-miR-4441	CLIP-seq
MIRT1093306	hsa-miR-4733-3p	CLIP-seq
MIRT1093309	hsa-miR-4739	CLIP-seq
MIRT1093311	hsa-miR-4756-5p	CLIP-seq
MIRT1093261	hsa-miR-1226	CLIP-seq
MIRT1093266	hsa-miR-1321	CLIP-seq
MIRT1093267	hsa-miR-146b-3p	CLIP-seq
MIRT1093273	hsa-miR-1915	CLIP-seq
MIRT1093291	hsa-miR-4270	CLIP-seq
MIRT1093297	hsa-miR-4441	CLIP-seq
MIRT1093306	hsa-miR-4733-3p	CLIP-seq
MIRT1093309	hsa-miR-4739	CLIP-seq
MIRT1093311	hsa-miR-4756-5p	CLIP-seq

Show/Hide all (29)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003777	Function	Microtubule motor activity	IBA
GO:0003777	Function	Microtubule motor activity	IEA
GO:0003777	Function	Microtubule motor activity	NAS	10859302
GO:0005515	Function	Protein binding	IPI	10859302, 21057110
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	10859302
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005871	Component	Kinesin complex	IBA
GO:0005874	Component	Microtubule	IBA
GO:0005874	Component	Microtubule	IEA
GO:0006605	Process	Protein targeting	TAS	10859302
GO:0007018	Process	Microtubule-based movement	IBA
GO:0007018	Process	Microtubule-based movement	IEA
GO:0007018	Process	Microtubule-based movement	TAS	10859302
GO:0007165	Process	Signal transduction	NAS	10859302
GO:0008017	Function	Microtubule binding	IBA
GO:0008017	Function	Microtubule binding	IEA
GO:0016887	Function	ATP hydrolysis activity	IBA
GO:0019901	Function	Protein kinase binding	IPI	10859302, 20194617
GO:0030424	Component	Axon	IDA	20194617
GO:0030424	Component	Axon	IEA
GO:0042110	Process	T cell activation	NAS	12496241
GO:0042995	Component	Cell projection	IEA
GO:0045184	Process	Establishment of protein localization	IEA
GO:0050770	Process	Regulation of axonogenesis	IDA	20194617
GO:0071889	Function	14-3-3 protein binding	IDA	20194617

MIM	HGNC	e!Ensembl
607350	14405	ENSG00000197892

Q9NQT8

Protein name

Kinesin-like protein KIF13B (Kinesin-like protein GAKIN)

Protein function

Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes. {ECO:0000269

PDB

2COW , 3FM8 , 3GBJ , 3MDB

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00225	Kinesin	11 → 353	Kinesin motor domain	Domain
PF16183	Kinesin_assoc	385 → 471	Kinesin-associated	Family
PF00498	FHA	471 → 535	FHA domain	Family
PF12423	KIF1B	756 → 802	Kinesin protein 1B	Family
PF12473	DUF3694	1003 → 1280	Kinesin protein	Family
PF01302	CAP_GLY	1703 → 1767	CAP-Gly domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous.

Sequence

MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH
CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP
GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG
PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG
TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN
KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVN
EDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEE
IAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQD
IQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFF
RLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKA
LGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFH
SPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIP
ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVI
RSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRL
SGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEP
VIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPR
KNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGI
FQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDM
DSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEE
RNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATL
TGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHP
ADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREA
LARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSI
SSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPD
PGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDI
RVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSP
LSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEE
PPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAP
GAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSG
KNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATN
LASLTAALAKADRSHKNPENRKSWAS

Sequence length

1826

Interactions

View interactions

	KEGG		Reactome
	Motor proteins		COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism spectrum disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORTICOBASAL DEGENERATION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Glioma	Glioma	Pubtator	36837615	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Henoch-Schoenlein Purpura	Henoch-Schonlein Nephritis	BEFREE	16636240		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	27863212		★★★★★ ★☆☆☆☆ Found in Text Mining only

KIF13B (kinesin family member 13B)