FBXW11 (F-box and WD repeat domain containing 11)

Gene

• Entrez ID: 23291
• Gene name: F-box and WD repeat domain containing 11
• Gene symbol: FBXW11
• Synonyms (NCBI Gene): BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, NEDJED
• Chromosome: 5
• Chromosome location: 5q35.1
• Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), w

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019282	hsa-miR-148b-3p	Microarray	17612493
MIRT051087	hsa-miR-16-5p	CLASH	23622248
MIRT042396	hsa-miR-450a-5p	CLASH	23622248
MIRT442267	hsa-miR-4475	PAR-CLIP	22100165
MIRT442268	hsa-miR-4433b-3p	PAR-CLIP	22100165
MIRT442266	hsa-miR-6760-5p	PAR-CLIP	22100165
MIRT442265	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT442264	hsa-miR-1909-5p	PAR-CLIP	22100165
MIRT442263	hsa-miR-4434	PAR-CLIP	22100165
MIRT442262	hsa-miR-4516	PAR-CLIP	22100165
MIRT442261	hsa-miR-5703	PAR-CLIP	22100165
MIRT442260	hsa-miR-504-3p	PAR-CLIP	22100165
MIRT442259	hsa-miR-6878-5p	PAR-CLIP	22100165
MIRT442258	hsa-miR-6892-5p	PAR-CLIP	22100165
MIRT358381	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT442267	hsa-miR-4475	PAR-CLIP	22100165
MIRT442268	hsa-miR-4433b-3p	PAR-CLIP	22100165
MIRT442266	hsa-miR-6760-5p	PAR-CLIP	22100165
MIRT442265	hsa-miR-6770-5p	PAR-CLIP	22100165
MIRT442264	hsa-miR-1909-5p	PAR-CLIP	22100165
MIRT442263	hsa-miR-4434	PAR-CLIP	22100165
MIRT442262	hsa-miR-4516	PAR-CLIP	22100165
MIRT442261	hsa-miR-5703	PAR-CLIP	22100165
MIRT442260	hsa-miR-504-3p	PAR-CLIP	22100165
MIRT442259	hsa-miR-6878-5p	PAR-CLIP	22100165
MIRT442258	hsa-miR-6892-5p	PAR-CLIP	22100165
MIRT358381	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT993073	hsa-miR-101	CLIP-seq
MIRT993074	hsa-miR-106a	CLIP-seq
MIRT993075	hsa-miR-106b	CLIP-seq
MIRT993076	hsa-miR-1205	CLIP-seq
MIRT993077	hsa-miR-1225-3p	CLIP-seq
MIRT993078	hsa-miR-1233	CLIP-seq
MIRT993079	hsa-miR-1237	CLIP-seq
MIRT993080	hsa-miR-1243	CLIP-seq
MIRT993081	hsa-miR-1244	CLIP-seq
MIRT993082	hsa-miR-1248	CLIP-seq
MIRT993083	hsa-miR-1252	CLIP-seq
MIRT993084	hsa-miR-1256	CLIP-seq
MIRT993085	hsa-miR-1286	CLIP-seq
MIRT993086	hsa-miR-1290	CLIP-seq
MIRT993087	hsa-miR-1291	CLIP-seq
MIRT993088	hsa-miR-1298	CLIP-seq
MIRT993089	hsa-miR-1304	CLIP-seq
MIRT993090	hsa-miR-130a	CLIP-seq
MIRT993091	hsa-miR-130b	CLIP-seq
MIRT993092	hsa-miR-132	CLIP-seq
MIRT993093	hsa-miR-1324	CLIP-seq
MIRT993094	hsa-miR-141	CLIP-seq
MIRT993095	hsa-miR-144	CLIP-seq
MIRT993096	hsa-miR-151-3p	CLIP-seq
MIRT993097	hsa-miR-17	CLIP-seq
MIRT993098	hsa-miR-1825	CLIP-seq
MIRT993099	hsa-miR-1912	CLIP-seq
MIRT993100	hsa-miR-1915	CLIP-seq
MIRT993101	hsa-miR-199a-3p	CLIP-seq
MIRT993102	hsa-miR-199b-3p	CLIP-seq
MIRT993103	hsa-miR-19a	CLIP-seq
MIRT993104	hsa-miR-19b	CLIP-seq
MIRT993105	hsa-miR-200a	CLIP-seq
MIRT993106	hsa-miR-200b	CLIP-seq
MIRT993107	hsa-miR-200c	CLIP-seq
MIRT993108	hsa-miR-20a	CLIP-seq
MIRT993109	hsa-miR-20b	CLIP-seq
MIRT993110	hsa-miR-212	CLIP-seq
MIRT993111	hsa-miR-217	CLIP-seq
MIRT993112	hsa-miR-2277-3p	CLIP-seq
MIRT993113	hsa-miR-2467-5p	CLIP-seq
MIRT993114	hsa-miR-301a	CLIP-seq
MIRT993115	hsa-miR-301b	CLIP-seq
MIRT993116	hsa-miR-302a	CLIP-seq
MIRT993117	hsa-miR-302b	CLIP-seq
MIRT993118	hsa-miR-302c	CLIP-seq
MIRT993119	hsa-miR-302d	CLIP-seq
MIRT993120	hsa-miR-302e	CLIP-seq
MIRT993121	hsa-miR-3065-5p	CLIP-seq
MIRT993122	hsa-miR-3127-3p	CLIP-seq
MIRT993123	hsa-miR-3129-5p	CLIP-seq
MIRT993124	hsa-miR-3130-5p	CLIP-seq
MIRT993125	hsa-miR-3166	CLIP-seq
MIRT993126	hsa-miR-3183	CLIP-seq
MIRT993127	hsa-miR-3188	CLIP-seq
MIRT993128	hsa-miR-3202	CLIP-seq
MIRT993129	hsa-miR-320a	CLIP-seq
MIRT993130	hsa-miR-320b	CLIP-seq
MIRT993131	hsa-miR-320c	CLIP-seq
MIRT993132	hsa-miR-320d	CLIP-seq
MIRT993133	hsa-miR-323-3p	CLIP-seq
MIRT993134	hsa-miR-329	CLIP-seq
MIRT993135	hsa-miR-330-3p	CLIP-seq
MIRT993136	hsa-miR-338-3p	CLIP-seq
MIRT993137	hsa-miR-342-5p	CLIP-seq
MIRT993138	hsa-miR-345	CLIP-seq
MIRT993139	hsa-miR-3591-5p	CLIP-seq
MIRT993140	hsa-miR-3613-3p	CLIP-seq
MIRT993141	hsa-miR-362-3p	CLIP-seq
MIRT993142	hsa-miR-3646	CLIP-seq
MIRT993143	hsa-miR-3654	CLIP-seq
MIRT993144	hsa-miR-3663-3p	CLIP-seq
MIRT993145	hsa-miR-3664-5p	CLIP-seq
MIRT993146	hsa-miR-3666	CLIP-seq
MIRT993147	hsa-miR-3679-3p	CLIP-seq
MIRT993148	hsa-miR-3689a-3p	CLIP-seq
MIRT993149	hsa-miR-3689c	CLIP-seq
MIRT993150	hsa-miR-3689d	CLIP-seq
MIRT993151	hsa-miR-3692	CLIP-seq
MIRT993152	hsa-miR-369-3p	CLIP-seq
MIRT993153	hsa-miR-371-5p	CLIP-seq
MIRT993154	hsa-miR-371b-5p	CLIP-seq
MIRT993155	hsa-miR-372	CLIP-seq
MIRT993156	hsa-miR-373	CLIP-seq
MIRT993157	hsa-miR-374a	CLIP-seq
MIRT993158	hsa-miR-374b	CLIP-seq
MIRT993159	hsa-miR-3908	CLIP-seq
MIRT993160	hsa-miR-3918	CLIP-seq
MIRT993161	hsa-miR-3924	CLIP-seq
MIRT993162	hsa-miR-3929	CLIP-seq
MIRT993163	hsa-miR-3941	CLIP-seq
MIRT993164	hsa-miR-3942-5p	CLIP-seq
MIRT993165	hsa-miR-3974	CLIP-seq
MIRT993166	hsa-miR-3975	CLIP-seq
MIRT993167	hsa-miR-4257	CLIP-seq
MIRT993168	hsa-miR-4286	CLIP-seq
MIRT993169	hsa-miR-429	CLIP-seq
MIRT993170	hsa-miR-4295	CLIP-seq
MIRT993171	hsa-miR-4418	CLIP-seq
MIRT993172	hsa-miR-4419b	CLIP-seq
MIRT993173	hsa-miR-4428	CLIP-seq
MIRT993174	hsa-miR-4429	CLIP-seq
MIRT993175	hsa-miR-4436b-5p	CLIP-seq
MIRT993176	hsa-miR-4476	CLIP-seq
MIRT993177	hsa-miR-4477a	CLIP-seq
MIRT993178	hsa-miR-4477b	CLIP-seq
MIRT993179	hsa-miR-4478	CLIP-seq
MIRT993180	hsa-miR-4482	CLIP-seq
MIRT993181	hsa-miR-4494	CLIP-seq
MIRT993182	hsa-miR-4503	CLIP-seq
MIRT993183	hsa-miR-4512	CLIP-seq
MIRT993184	hsa-miR-4528	CLIP-seq
MIRT993185	hsa-miR-4530	CLIP-seq
MIRT993186	hsa-miR-4533	CLIP-seq
MIRT993187	hsa-miR-454	CLIP-seq
MIRT993188	hsa-miR-4635	CLIP-seq
MIRT993189	hsa-miR-4638-3p	CLIP-seq
MIRT993190	hsa-miR-4641	CLIP-seq
MIRT993191	hsa-miR-4651	CLIP-seq
MIRT993192	hsa-miR-4664-5p	CLIP-seq
MIRT993193	hsa-miR-4668-3p	CLIP-seq
MIRT993194	hsa-miR-4676-5p	CLIP-seq
MIRT993195	hsa-miR-4685-5p	CLIP-seq
MIRT993196	hsa-miR-4690-3p	CLIP-seq
MIRT993197	hsa-miR-4699-3p	CLIP-seq
MIRT993198	hsa-miR-4703-5p	CLIP-seq
MIRT993199	hsa-miR-4709-3p	CLIP-seq
MIRT993200	hsa-miR-4719	CLIP-seq
MIRT993201	hsa-miR-4722-5p	CLIP-seq
MIRT993202	hsa-miR-4723-3p	CLIP-seq
MIRT993203	hsa-miR-4726-3p	CLIP-seq
MIRT993204	hsa-miR-4728-5p	CLIP-seq
MIRT993205	hsa-miR-4732-3p	CLIP-seq
MIRT993206	hsa-miR-4733-5p	CLIP-seq
MIRT993207	hsa-miR-4742-3p	CLIP-seq
MIRT993208	hsa-miR-4747-5p	CLIP-seq
MIRT993209	hsa-miR-4760-3p	CLIP-seq
MIRT993210	hsa-miR-4766-3p	CLIP-seq
MIRT993211	hsa-miR-4771	CLIP-seq
MIRT993212	hsa-miR-4786-3p	CLIP-seq
MIRT993213	hsa-miR-483-3p	CLIP-seq
MIRT993214	hsa-miR-485-5p	CLIP-seq
MIRT993215	hsa-miR-508-5p	CLIP-seq
MIRT993216	hsa-miR-509-3-5p	CLIP-seq
MIRT993217	hsa-miR-509-5p	CLIP-seq
MIRT993218	hsa-miR-513c	CLIP-seq
MIRT993219	hsa-miR-514	CLIP-seq
MIRT993220	hsa-miR-514b-3p	CLIP-seq
MIRT993221	hsa-miR-514b-5p	CLIP-seq
MIRT993222	hsa-miR-518a-5p	CLIP-seq
MIRT993223	hsa-miR-519a	CLIP-seq
MIRT993224	hsa-miR-519b-3p	CLIP-seq
MIRT993225	hsa-miR-519c-3p	CLIP-seq
MIRT993226	hsa-miR-519d	CLIP-seq
MIRT993227	hsa-miR-520a-3p	CLIP-seq
MIRT993228	hsa-miR-520b	CLIP-seq
MIRT993229	hsa-miR-520c-3p	CLIP-seq
MIRT993230	hsa-miR-520d-3p	CLIP-seq
MIRT993231	hsa-miR-520d-5p	CLIP-seq
MIRT993232	hsa-miR-520e	CLIP-seq
MIRT993233	hsa-miR-520f	CLIP-seq
MIRT993234	hsa-miR-520g	CLIP-seq
MIRT993235	hsa-miR-520h	CLIP-seq
MIRT993236	hsa-miR-524-5p	CLIP-seq
MIRT993237	hsa-miR-526b	CLIP-seq
MIRT993238	hsa-miR-527	CLIP-seq
MIRT993239	hsa-miR-539	CLIP-seq
MIRT993240	hsa-miR-548ac	CLIP-seq
MIRT993241	hsa-miR-548ae	CLIP-seq
MIRT993242	hsa-miR-548ag	CLIP-seq
MIRT993243	hsa-miR-548ai	CLIP-seq
MIRT993244	hsa-miR-548aj	CLIP-seq
MIRT993245	hsa-miR-548am	CLIP-seq
MIRT993246	hsa-miR-548c-3p	CLIP-seq
MIRT993247	hsa-miR-548d-3p	CLIP-seq
MIRT993248	hsa-miR-548g	CLIP-seq
MIRT993249	hsa-miR-548x	CLIP-seq
MIRT993250	hsa-miR-548z	CLIP-seq
MIRT993251	hsa-miR-549	CLIP-seq
MIRT993252	hsa-miR-568	CLIP-seq
MIRT993253	hsa-miR-575	CLIP-seq
MIRT993254	hsa-miR-603	CLIP-seq
MIRT993255	hsa-miR-607	CLIP-seq
MIRT993256	hsa-miR-608	CLIP-seq
MIRT993257	hsa-miR-664	CLIP-seq
MIRT993258	hsa-miR-766	CLIP-seq
MIRT993259	hsa-miR-889	CLIP-seq
MIRT993260	hsa-miR-891b	CLIP-seq
MIRT993261	hsa-miR-93	CLIP-seq
MIRT993092	hsa-miR-132	CLIP-seq
MIRT993093	hsa-miR-1324	CLIP-seq
MIRT993110	hsa-miR-212	CLIP-seq
MIRT993121	hsa-miR-3065-5p	CLIP-seq
MIRT993129	hsa-miR-320a	CLIP-seq
MIRT993130	hsa-miR-320b	CLIP-seq
MIRT993131	hsa-miR-320c	CLIP-seq
MIRT993132	hsa-miR-320d	CLIP-seq
MIRT993174	hsa-miR-4429	CLIP-seq
MIRT993231	hsa-miR-520d-5p	CLIP-seq
MIRT993236	hsa-miR-524-5p	CLIP-seq
MIRT993240	hsa-miR-548ac	CLIP-seq
MIRT993241	hsa-miR-548ae	CLIP-seq
MIRT993244	hsa-miR-548aj	CLIP-seq
MIRT993245	hsa-miR-548am	CLIP-seq
MIRT993247	hsa-miR-548d-3p	CLIP-seq
MIRT993249	hsa-miR-548x	CLIP-seq
MIRT993250	hsa-miR-548z	CLIP-seq
MIRT993251	hsa-miR-549	CLIP-seq
MIRT993259	hsa-miR-889	CLIP-seq
MIRT993073	hsa-miR-101	CLIP-seq
MIRT993095	hsa-miR-144	CLIP-seq
MIRT1548675	hsa-miR-3612	CLIP-seq
MIRT1548676	hsa-miR-4266	CLIP-seq
MIRT1548677	hsa-miR-4695-5p	CLIP-seq
MIRT1548678	hsa-miR-4779	CLIP-seq
MIRT1548679	hsa-miR-650	CLIP-seq
MIRT993073	hsa-miR-101	CLIP-seq
MIRT993074	hsa-miR-106a	CLIP-seq
MIRT993075	hsa-miR-106b	CLIP-seq
MIRT993076	hsa-miR-1205	CLIP-seq
MIRT1994484	hsa-miR-1207-3p	CLIP-seq
MIRT993077	hsa-miR-1225-3p	CLIP-seq
MIRT1994485	hsa-miR-1231	CLIP-seq
MIRT993078	hsa-miR-1233	CLIP-seq
MIRT993079	hsa-miR-1237	CLIP-seq
MIRT993081	hsa-miR-1244	CLIP-seq
MIRT993082	hsa-miR-1248	CLIP-seq
MIRT993083	hsa-miR-1252	CLIP-seq
MIRT993084	hsa-miR-1256	CLIP-seq
MIRT1994486	hsa-miR-1262	CLIP-seq
MIRT1994487	hsa-miR-1264	CLIP-seq
MIRT993087	hsa-miR-1291	CLIP-seq
MIRT993089	hsa-miR-1304	CLIP-seq
MIRT993090	hsa-miR-130a	CLIP-seq
MIRT993091	hsa-miR-130b	CLIP-seq
MIRT993092	hsa-miR-132	CLIP-seq
MIRT993093	hsa-miR-1324	CLIP-seq
MIRT1994488	hsa-miR-143	CLIP-seq
MIRT993095	hsa-miR-144	CLIP-seq
MIRT1994489	hsa-miR-150	CLIP-seq
MIRT993097	hsa-miR-17	CLIP-seq
MIRT1994490	hsa-miR-182	CLIP-seq
MIRT993101	hsa-miR-199a-3p	CLIP-seq
MIRT993102	hsa-miR-199b-3p	CLIP-seq
MIRT993103	hsa-miR-19a	CLIP-seq
MIRT993104	hsa-miR-19b	CLIP-seq
MIRT993108	hsa-miR-20a	CLIP-seq
MIRT993109	hsa-miR-20b	CLIP-seq
MIRT993110	hsa-miR-212	CLIP-seq
MIRT993113	hsa-miR-2467-5p	CLIP-seq
MIRT1994491	hsa-miR-2861	CLIP-seq
MIRT993114	hsa-miR-301a	CLIP-seq
MIRT993115	hsa-miR-301b	CLIP-seq
MIRT993116	hsa-miR-302a	CLIP-seq
MIRT993117	hsa-miR-302b	CLIP-seq
MIRT993118	hsa-miR-302c	CLIP-seq
MIRT993119	hsa-miR-302d	CLIP-seq
MIRT993120	hsa-miR-302e	CLIP-seq
MIRT1994492	hsa-miR-3126-5p	CLIP-seq
MIRT993123	hsa-miR-3129-5p	CLIP-seq
MIRT993125	hsa-miR-3166	CLIP-seq
MIRT1994493	hsa-miR-3182	CLIP-seq
MIRT1994494	hsa-miR-3185	CLIP-seq
MIRT993127	hsa-miR-3188	CLIP-seq
MIRT1994495	hsa-miR-3189-3p	CLIP-seq
MIRT993129	hsa-miR-320a	CLIP-seq
MIRT993130	hsa-miR-320b	CLIP-seq
MIRT993131	hsa-miR-320c	CLIP-seq
MIRT993132	hsa-miR-320d	CLIP-seq
MIRT993133	hsa-miR-323-3p	CLIP-seq
MIRT1994496	hsa-miR-323b-5p	CLIP-seq
MIRT993134	hsa-miR-329	CLIP-seq
MIRT993135	hsa-miR-330-3p	CLIP-seq
MIRT1994497	hsa-miR-331-3p	CLIP-seq
MIRT993136	hsa-miR-338-3p	CLIP-seq
MIRT993137	hsa-miR-342-5p	CLIP-seq
MIRT1994498	hsa-miR-346	CLIP-seq
MIRT1994499	hsa-miR-3607-3p	CLIP-seq
MIRT1994500	hsa-miR-3622a-5p	CLIP-seq
MIRT993141	hsa-miR-362-3p	CLIP-seq
MIRT993142	hsa-miR-3646	CLIP-seq
MIRT1994501	hsa-miR-3647-3p	CLIP-seq
MIRT1994502	hsa-miR-3661	CLIP-seq
MIRT993144	hsa-miR-3663-3p	CLIP-seq
MIRT1994503	hsa-miR-3664-3p	CLIP-seq
MIRT993146	hsa-miR-3666	CLIP-seq
MIRT1994504	hsa-miR-3682-5p	CLIP-seq
MIRT1994505	hsa-miR-3686	CLIP-seq
MIRT993148	hsa-miR-3689a-3p	CLIP-seq
MIRT993149	hsa-miR-3689c	CLIP-seq
MIRT993150	hsa-miR-3689d	CLIP-seq
MIRT1994506	hsa-miR-3691-3p	CLIP-seq
MIRT993151	hsa-miR-3692	CLIP-seq
MIRT993153	hsa-miR-371-5p	CLIP-seq
MIRT993154	hsa-miR-371b-5p	CLIP-seq
MIRT993155	hsa-miR-372	CLIP-seq
MIRT993156	hsa-miR-373	CLIP-seq
MIRT1994507	hsa-miR-3919	CLIP-seq
MIRT993161	hsa-miR-3924	CLIP-seq
MIRT993164	hsa-miR-3942-5p	CLIP-seq
MIRT993166	hsa-miR-3975	CLIP-seq
MIRT1548676	hsa-miR-4266	CLIP-seq
MIRT1994508	hsa-miR-4267	CLIP-seq
MIRT1994509	hsa-miR-4272	CLIP-seq
MIRT1994510	hsa-miR-4282	CLIP-seq
MIRT1994511	hsa-miR-4287	CLIP-seq
MIRT1994512	hsa-miR-4288	CLIP-seq
MIRT1994513	hsa-miR-4293	CLIP-seq
MIRT993170	hsa-miR-4295	CLIP-seq
MIRT1994514	hsa-miR-4310	CLIP-seq
MIRT1994515	hsa-miR-4419a	CLIP-seq
MIRT1994516	hsa-miR-4420	CLIP-seq
MIRT1994517	hsa-miR-4423-3p	CLIP-seq
MIRT993173	hsa-miR-4428	CLIP-seq
MIRT993174	hsa-miR-4429	CLIP-seq
MIRT1994518	hsa-miR-4433	CLIP-seq
MIRT993175	hsa-miR-4436b-5p	CLIP-seq
MIRT1994519	hsa-miR-4459	CLIP-seq
MIRT993177	hsa-miR-4477a	CLIP-seq
MIRT1994520	hsa-miR-448	CLIP-seq
MIRT1994521	hsa-miR-4480	CLIP-seq
MIRT993181	hsa-miR-4494	CLIP-seq
MIRT1994522	hsa-miR-4496	CLIP-seq
MIRT1994523	hsa-miR-4502	CLIP-seq
MIRT993182	hsa-miR-4503	CLIP-seq
MIRT1994524	hsa-miR-4510	CLIP-seq
MIRT993184	hsa-miR-4528	CLIP-seq
MIRT1994525	hsa-miR-4529-5p	CLIP-seq
MIRT993185	hsa-miR-4530	CLIP-seq
MIRT993186	hsa-miR-4533	CLIP-seq
MIRT1994526	hsa-miR-4539	CLIP-seq
MIRT993187	hsa-miR-454	CLIP-seq
MIRT993190	hsa-miR-4641	CLIP-seq
MIRT993191	hsa-miR-4651	CLIP-seq
MIRT1994527	hsa-miR-4652-3p	CLIP-seq
MIRT993192	hsa-miR-4664-5p	CLIP-seq
MIRT993194	hsa-miR-4676-5p	CLIP-seq
MIRT1994528	hsa-miR-4685-3p	CLIP-seq
MIRT993196	hsa-miR-4690-3p	CLIP-seq
MIRT1548677	hsa-miR-4695-5p	CLIP-seq
MIRT993197	hsa-miR-4699-3p	CLIP-seq
MIRT1994529	hsa-miR-4701-3p	CLIP-seq
MIRT993198	hsa-miR-4703-5p	CLIP-seq
MIRT1994530	hsa-miR-4712-3p	CLIP-seq
MIRT1994531	hsa-miR-4713-5p	CLIP-seq
MIRT993200	hsa-miR-4719	CLIP-seq
MIRT993203	hsa-miR-4726-3p	CLIP-seq
MIRT993204	hsa-miR-4728-5p	CLIP-seq
MIRT993207	hsa-miR-4742-3p	CLIP-seq
MIRT993208	hsa-miR-4747-5p	CLIP-seq
MIRT1994532	hsa-miR-4753-3p	CLIP-seq
MIRT1994533	hsa-miR-4753-5p	CLIP-seq
MIRT1994534	hsa-miR-4756-3p	CLIP-seq
MIRT1994535	hsa-miR-4757-5p	CLIP-seq
MIRT993209	hsa-miR-4760-3p	CLIP-seq
MIRT1994536	hsa-miR-4768-3p	CLIP-seq
MIRT1994537	hsa-miR-4770	CLIP-seq
MIRT993211	hsa-miR-4771	CLIP-seq
MIRT1548678	hsa-miR-4779	CLIP-seq
MIRT993212	hsa-miR-4786-3p	CLIP-seq
MIRT1994538	hsa-miR-4803	CLIP-seq
MIRT993213	hsa-miR-483-3p	CLIP-seq
MIRT993214	hsa-miR-485-5p	CLIP-seq
MIRT993215	hsa-miR-508-5p	CLIP-seq
MIRT1994539	hsa-miR-510	CLIP-seq
MIRT1994540	hsa-miR-512-5p	CLIP-seq
MIRT1994541	hsa-miR-513a-3p	CLIP-seq
MIRT993218	hsa-miR-513c	CLIP-seq
MIRT993221	hsa-miR-514b-5p	CLIP-seq
MIRT993222	hsa-miR-518a-5p	CLIP-seq
MIRT993223	hsa-miR-519a	CLIP-seq
MIRT993224	hsa-miR-519b-3p	CLIP-seq
MIRT993225	hsa-miR-519c-3p	CLIP-seq
MIRT993226	hsa-miR-519d	CLIP-seq
MIRT993227	hsa-miR-520a-3p	CLIP-seq
MIRT993228	hsa-miR-520b	CLIP-seq
MIRT993229	hsa-miR-520c-3p	CLIP-seq
MIRT993230	hsa-miR-520d-3p	CLIP-seq
MIRT993231	hsa-miR-520d-5p	CLIP-seq
MIRT993232	hsa-miR-520e	CLIP-seq
MIRT993234	hsa-miR-520g	CLIP-seq
MIRT993235	hsa-miR-520h	CLIP-seq
MIRT993236	hsa-miR-524-5p	CLIP-seq
MIRT993237	hsa-miR-526b	CLIP-seq
MIRT993238	hsa-miR-527	CLIP-seq
MIRT1994542	hsa-miR-532-3p	CLIP-seq
MIRT993248	hsa-miR-548g	CLIP-seq
MIRT993253	hsa-miR-575	CLIP-seq
MIRT993255	hsa-miR-607	CLIP-seq
MIRT993256	hsa-miR-608	CLIP-seq
MIRT1994543	hsa-miR-631	CLIP-seq
MIRT1994544	hsa-miR-632	CLIP-seq
MIRT993258	hsa-miR-766	CLIP-seq
MIRT993259	hsa-miR-889	CLIP-seq
MIRT993260	hsa-miR-891b	CLIP-seq
MIRT993261	hsa-miR-93	CLIP-seq
MIRT1994545	hsa-miR-942	CLIP-seq
MIRT1994484	hsa-miR-1207-3p	CLIP-seq
MIRT993077	hsa-miR-1225-3p	CLIP-seq
MIRT993078	hsa-miR-1233	CLIP-seq
MIRT993084	hsa-miR-1256	CLIP-seq
MIRT1994486	hsa-miR-1262	CLIP-seq
MIRT1994487	hsa-miR-1264	CLIP-seq
MIRT993087	hsa-miR-1291	CLIP-seq
MIRT993089	hsa-miR-1304	CLIP-seq
MIRT1994488	hsa-miR-143	CLIP-seq
MIRT1994490	hsa-miR-182	CLIP-seq
MIRT2228556	hsa-miR-1913	CLIP-seq
MIRT993113	hsa-miR-2467-5p	CLIP-seq
MIRT993116	hsa-miR-302a	CLIP-seq
MIRT993117	hsa-miR-302b	CLIP-seq
MIRT993118	hsa-miR-302c	CLIP-seq
MIRT993119	hsa-miR-302d	CLIP-seq
MIRT993120	hsa-miR-302e	CLIP-seq
MIRT2228557	hsa-miR-3124-3p	CLIP-seq
MIRT2228558	hsa-miR-3145-3p	CLIP-seq
MIRT993127	hsa-miR-3188	CLIP-seq
MIRT1994495	hsa-miR-3189-3p	CLIP-seq
MIRT2228559	hsa-miR-324-3p	CLIP-seq
MIRT993134	hsa-miR-329	CLIP-seq
MIRT993135	hsa-miR-330-3p	CLIP-seq
MIRT1994497	hsa-miR-331-3p	CLIP-seq
MIRT993136	hsa-miR-338-3p	CLIP-seq
MIRT993137	hsa-miR-342-5p	CLIP-seq
MIRT993138	hsa-miR-345	CLIP-seq
MIRT993139	hsa-miR-3591-5p	CLIP-seq
MIRT1994500	hsa-miR-3622a-5p	CLIP-seq
MIRT993141	hsa-miR-362-3p	CLIP-seq
MIRT993145	hsa-miR-3664-5p	CLIP-seq
MIRT993147	hsa-miR-3679-3p	CLIP-seq
MIRT2228560	hsa-miR-3685	CLIP-seq
MIRT1994506	hsa-miR-3691-3p	CLIP-seq
MIRT993151	hsa-miR-3692	CLIP-seq
MIRT993155	hsa-miR-372	CLIP-seq
MIRT993156	hsa-miR-373	CLIP-seq
MIRT2228561	hsa-miR-378g	CLIP-seq
MIRT2228562	hsa-miR-384	CLIP-seq
MIRT993161	hsa-miR-3924	CLIP-seq
MIRT993163	hsa-miR-3941	CLIP-seq
MIRT993164	hsa-miR-3942-5p	CLIP-seq
MIRT993166	hsa-miR-3975	CLIP-seq
MIRT1548676	hsa-miR-4266	CLIP-seq
MIRT1994511	hsa-miR-4287	CLIP-seq
MIRT2228563	hsa-miR-4292	CLIP-seq
MIRT2228564	hsa-miR-4313	CLIP-seq
MIRT1994517	hsa-miR-4423-3p	CLIP-seq
MIRT993175	hsa-miR-4436b-5p	CLIP-seq
MIRT1994521	hsa-miR-4480	CLIP-seq
MIRT993185	hsa-miR-4530	CLIP-seq
MIRT993190	hsa-miR-4641	CLIP-seq
MIRT993191	hsa-miR-4651	CLIP-seq
MIRT993192	hsa-miR-4664-5p	CLIP-seq
MIRT1994528	hsa-miR-4685-3p	CLIP-seq
MIRT993196	hsa-miR-4690-3p	CLIP-seq
MIRT1548677	hsa-miR-4695-5p	CLIP-seq
MIRT993197	hsa-miR-4699-3p	CLIP-seq
MIRT1994529	hsa-miR-4701-3p	CLIP-seq
MIRT993198	hsa-miR-4703-5p	CLIP-seq
MIRT993203	hsa-miR-4726-3p	CLIP-seq
MIRT993205	hsa-miR-4732-3p	CLIP-seq
MIRT993207	hsa-miR-4742-3p	CLIP-seq
MIRT1994532	hsa-miR-4753-3p	CLIP-seq
MIRT1994534	hsa-miR-4756-3p	CLIP-seq
MIRT1994536	hsa-miR-4768-3p	CLIP-seq
MIRT1994537	hsa-miR-4770	CLIP-seq
MIRT1548678	hsa-miR-4779	CLIP-seq
MIRT993213	hsa-miR-483-3p	CLIP-seq
MIRT993214	hsa-miR-485-5p	CLIP-seq
MIRT993215	hsa-miR-508-5p	CLIP-seq
MIRT1994540	hsa-miR-512-5p	CLIP-seq
MIRT993218	hsa-miR-513c	CLIP-seq
MIRT993221	hsa-miR-514b-5p	CLIP-seq
MIRT993223	hsa-miR-519a	CLIP-seq
MIRT993224	hsa-miR-519b-3p	CLIP-seq
MIRT993225	hsa-miR-519c-3p	CLIP-seq
MIRT993227	hsa-miR-520a-3p	CLIP-seq
MIRT2228565	hsa-miR-520a-5p	CLIP-seq
MIRT993228	hsa-miR-520b	CLIP-seq
MIRT993229	hsa-miR-520c-3p	CLIP-seq
MIRT993230	hsa-miR-520d-3p	CLIP-seq
MIRT993232	hsa-miR-520e	CLIP-seq
MIRT2228566	hsa-miR-525-5p	CLIP-seq
MIRT993237	hsa-miR-526b	CLIP-seq
MIRT993248	hsa-miR-548g	CLIP-seq
MIRT2228567	hsa-miR-584	CLIP-seq
MIRT993254	hsa-miR-603	CLIP-seq
MIRT993256	hsa-miR-608	CLIP-seq
MIRT993258	hsa-miR-766	CLIP-seq
MIRT2228568	hsa-miR-877	CLIP-seq
MIRT993260	hsa-miR-891b	CLIP-seq
MIRT1994545	hsa-miR-942	CLIP-seq
MIRT993081	hsa-miR-1244	CLIP-seq
MIRT993151	hsa-miR-3692	CLIP-seq
MIRT993152	hsa-miR-369-3p	CLIP-seq
MIRT993173	hsa-miR-4428	CLIP-seq
MIRT993197	hsa-miR-4699-3p	CLIP-seq
MIRT993213	hsa-miR-483-3p	CLIP-seq
MIRT1994541	hsa-miR-513a-3p	CLIP-seq
MIRT993223	hsa-miR-519a	CLIP-seq
MIRT993224	hsa-miR-519b-3p	CLIP-seq
MIRT993225	hsa-miR-519c-3p	CLIP-seq
MIRT993073	hsa-miR-101	CLIP-seq
MIRT993087	hsa-miR-1291	CLIP-seq
MIRT993089	hsa-miR-1304	CLIP-seq
MIRT993095	hsa-miR-144	CLIP-seq
MIRT993133	hsa-miR-323-3p	CLIP-seq
MIRT993136	hsa-miR-338-3p	CLIP-seq
MIRT993138	hsa-miR-345	CLIP-seq
MIRT993151	hsa-miR-3692	CLIP-seq
MIRT993161	hsa-miR-3924	CLIP-seq
MIRT993177	hsa-miR-4477a	CLIP-seq
MIRT993182	hsa-miR-4503	CLIP-seq
MIRT993184	hsa-miR-4528	CLIP-seq
MIRT993185	hsa-miR-4530	CLIP-seq
MIRT993205	hsa-miR-4732-3p	CLIP-seq
MIRT993215	hsa-miR-508-5p	CLIP-seq
MIRT993231	hsa-miR-520d-5p	CLIP-seq
MIRT993236	hsa-miR-524-5p	CLIP-seq
MIRT993248	hsa-miR-548g	CLIP-seq
MIRT993258	hsa-miR-766	CLIP-seq
MIRT993260	hsa-miR-891b	CLIP-seq
MIRT1994538	hsa-miR-4803	CLIP-seq
MIRT993089	hsa-miR-1304	CLIP-seq
MIRT993133	hsa-miR-323-3p	CLIP-seq
MIRT993136	hsa-miR-338-3p	CLIP-seq
MIRT993161	hsa-miR-3924	CLIP-seq
MIRT993184	hsa-miR-4528	CLIP-seq
MIRT993185	hsa-miR-4530	CLIP-seq
MIRT993215	hsa-miR-508-5p	CLIP-seq
MIRT993248	hsa-miR-548g	CLIP-seq
MIRT993258	hsa-miR-766	CLIP-seq
MIRT993260	hsa-miR-891b	CLIP-seq
MIRT2228556	hsa-miR-1913	CLIP-seq
MIRT2449575	hsa-miR-3152-5p	CLIP-seq
MIRT2228559	hsa-miR-324-3p	CLIP-seq
MIRT1994497	hsa-miR-331-3p	CLIP-seq
MIRT993147	hsa-miR-3679-3p	CLIP-seq
MIRT1994511	hsa-miR-4287	CLIP-seq
MIRT2228564	hsa-miR-4313	CLIP-seq
MIRT1994528	hsa-miR-4685-3p	CLIP-seq
MIRT993073	hsa-miR-101	CLIP-seq
MIRT993084	hsa-miR-1256	CLIP-seq
MIRT993089	hsa-miR-1304	CLIP-seq
MIRT1994488	hsa-miR-143	CLIP-seq
MIRT993095	hsa-miR-144	CLIP-seq
MIRT2532291	hsa-miR-186	CLIP-seq
MIRT2228556	hsa-miR-1913	CLIP-seq
MIRT993112	hsa-miR-2277-3p	CLIP-seq
MIRT993113	hsa-miR-2467-5p	CLIP-seq
MIRT1994491	hsa-miR-2861	CLIP-seq
MIRT2449575	hsa-miR-3152-5p	CLIP-seq
MIRT993127	hsa-miR-3188	CLIP-seq
MIRT993133	hsa-miR-323-3p	CLIP-seq
MIRT2228559	hsa-miR-324-3p	CLIP-seq
MIRT1994497	hsa-miR-331-3p	CLIP-seq
MIRT993136	hsa-miR-338-3p	CLIP-seq
MIRT993137	hsa-miR-342-5p	CLIP-seq
MIRT993140	hsa-miR-3613-3p	CLIP-seq
MIRT993142	hsa-miR-3646	CLIP-seq
MIRT1994502	hsa-miR-3661	CLIP-seq
MIRT993144	hsa-miR-3663-3p	CLIP-seq
MIRT1994503	hsa-miR-3664-3p	CLIP-seq
MIRT993147	hsa-miR-3679-3p	CLIP-seq
MIRT993148	hsa-miR-3689a-3p	CLIP-seq
MIRT993149	hsa-miR-3689c	CLIP-seq
MIRT993150	hsa-miR-3689d	CLIP-seq
MIRT993161	hsa-miR-3924	CLIP-seq
MIRT993166	hsa-miR-3975	CLIP-seq
MIRT1548676	hsa-miR-4266	CLIP-seq
MIRT1994511	hsa-miR-4287	CLIP-seq
MIRT1994513	hsa-miR-4293	CLIP-seq
MIRT1994514	hsa-miR-4310	CLIP-seq
MIRT2228564	hsa-miR-4313	CLIP-seq
MIRT1994518	hsa-miR-4433	CLIP-seq
MIRT993175	hsa-miR-4436b-5p	CLIP-seq
MIRT1994519	hsa-miR-4459	CLIP-seq
MIRT2532292	hsa-miR-4511	CLIP-seq
MIRT993184	hsa-miR-4528	CLIP-seq
MIRT993185	hsa-miR-4530	CLIP-seq
MIRT1994526	hsa-miR-4539	CLIP-seq
MIRT993191	hsa-miR-4651	CLIP-seq
MIRT993192	hsa-miR-4664-5p	CLIP-seq
MIRT1994528	hsa-miR-4685-3p	CLIP-seq
MIRT1548677	hsa-miR-4695-5p	CLIP-seq
MIRT1994530	hsa-miR-4712-3p	CLIP-seq
MIRT993204	hsa-miR-4728-5p	CLIP-seq
MIRT1994534	hsa-miR-4756-3p	CLIP-seq
MIRT1994535	hsa-miR-4757-5p	CLIP-seq
MIRT1994536	hsa-miR-4768-3p	CLIP-seq
MIRT1994537	hsa-miR-4770	CLIP-seq
MIRT1548678	hsa-miR-4779	CLIP-seq
MIRT993212	hsa-miR-4786-3p	CLIP-seq
MIRT993213	hsa-miR-483-3p	CLIP-seq
MIRT993214	hsa-miR-485-5p	CLIP-seq
MIRT993215	hsa-miR-508-5p	CLIP-seq
MIRT1994539	hsa-miR-510	CLIP-seq
MIRT1994540	hsa-miR-512-5p	CLIP-seq
MIRT993239	hsa-miR-539	CLIP-seq
MIRT2532293	hsa-miR-548b-3p	CLIP-seq
MIRT993248	hsa-miR-548g	CLIP-seq
MIRT993256	hsa-miR-608	CLIP-seq
MIRT1994543	hsa-miR-631	CLIP-seq
MIRT993258	hsa-miR-766	CLIP-seq
MIRT993260	hsa-miR-891b	CLIP-seq
MIRT993073	hsa-miR-101	CLIP-seq
MIRT993076	hsa-miR-1205	CLIP-seq
MIRT993084	hsa-miR-1256	CLIP-seq
MIRT993089	hsa-miR-1304	CLIP-seq
MIRT1994488	hsa-miR-143	CLIP-seq
MIRT993095	hsa-miR-144	CLIP-seq
MIRT2680905	hsa-miR-146b-3p	CLIP-seq
MIRT2228556	hsa-miR-1913	CLIP-seq
MIRT993100	hsa-miR-1915	CLIP-seq
MIRT993113	hsa-miR-2467-5p	CLIP-seq
MIRT1994491	hsa-miR-2861	CLIP-seq
MIRT2449575	hsa-miR-3152-5p	CLIP-seq
MIRT2680906	hsa-miR-3173-5p	CLIP-seq
MIRT993127	hsa-miR-3188	CLIP-seq
MIRT993133	hsa-miR-323-3p	CLIP-seq
MIRT2228559	hsa-miR-324-3p	CLIP-seq
MIRT1994497	hsa-miR-331-3p	CLIP-seq
MIRT993136	hsa-miR-338-3p	CLIP-seq
MIRT993137	hsa-miR-342-5p	CLIP-seq
MIRT993140	hsa-miR-3613-3p	CLIP-seq
MIRT1994502	hsa-miR-3661	CLIP-seq
MIRT993144	hsa-miR-3663-3p	CLIP-seq
MIRT993147	hsa-miR-3679-3p	CLIP-seq
MIRT993160	hsa-miR-3918	CLIP-seq
MIRT993161	hsa-miR-3924	CLIP-seq
MIRT993166	hsa-miR-3975	CLIP-seq
MIRT1548676	hsa-miR-4266	CLIP-seq
MIRT1994511	hsa-miR-4287	CLIP-seq
MIRT1994513	hsa-miR-4293	CLIP-seq
MIRT2680907	hsa-miR-4297	CLIP-seq
MIRT1994514	hsa-miR-4310	CLIP-seq
MIRT2228564	hsa-miR-4313	CLIP-seq
MIRT993175	hsa-miR-4436b-5p	CLIP-seq
MIRT993183	hsa-miR-4512	CLIP-seq
MIRT993184	hsa-miR-4528	CLIP-seq
MIRT993185	hsa-miR-4530	CLIP-seq
MIRT1994526	hsa-miR-4539	CLIP-seq
MIRT993191	hsa-miR-4651	CLIP-seq
MIRT993192	hsa-miR-4664-5p	CLIP-seq
MIRT1994528	hsa-miR-4685-3p	CLIP-seq
MIRT993195	hsa-miR-4685-5p	CLIP-seq
MIRT1994534	hsa-miR-4756-3p	CLIP-seq
MIRT1994535	hsa-miR-4757-5p	CLIP-seq
MIRT1994537	hsa-miR-4770	CLIP-seq
MIRT993213	hsa-miR-483-3p	CLIP-seq
MIRT993214	hsa-miR-485-5p	CLIP-seq
MIRT993215	hsa-miR-508-5p	CLIP-seq
MIRT993248	hsa-miR-548g	CLIP-seq
MIRT993256	hsa-miR-608	CLIP-seq
MIRT1994543	hsa-miR-631	CLIP-seq
MIRT993258	hsa-miR-766	CLIP-seq
MIRT2680908	hsa-miR-874	CLIP-seq
MIRT993260	hsa-miR-891b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000132	Process	Establishment of mitotic spindle orientation	IBA
GO:0000151	Component	Ubiquitin ligase complex	NAS	10531035
GO:0000209	Process	Protein polyubiquitination	IDA	20347421
GO:0000209	Process	Protein polyubiquitination	IEA
GO:0000776	Component	Kinetochore	IBA
GO:0005515	Function	Protein binding	IPI	12482991, 14532120, 14743216, 15070733, 15917222, 16880511, 16885022, 17510365, 18354482, 18354483, 19159283, 19615732, 19966869, 20347421, 20708156, 21145461, 22307056, 22682247, 25241761, 25609649, 27705803, 29420262, 32911434, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005635	Component	Nuclear envelope	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005829	Component	Cytosol	ISS
GO:0005829	Component	Cytosol	TAS
GO:0005875	Component	Microtubule associated complex	IBA
GO:0005881	Component	Cytoplasmic microtubule	IBA
GO:0006470	Process	Protein dephosphorylation	ISS
GO:0007097	Process	Nuclear migration	IBA
GO:0007281	Process	Germ cell development	IBA
GO:0008090	Process	Retrograde axonal transport	IBA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016567	Process	Protein ubiquitination	IDA	16885022
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	NAS	10531035
GO:0019005	Component	SCF ubiquitin ligase complex	IDA	16880511, 20347421
GO:0019005	Component	SCF ubiquitin ligase complex	IEA
GO:0031023	Process	Microtubule organizing center organization	IBA
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IDA	20347421, 22017875, 22017876, 36608670
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IEA
GO:0031648	Process	Protein destabilization	IEA
GO:0031648	Process	Protein destabilization	IMP	16885022
GO:0042753	Process	Positive regulation of circadian rhythm	ISS
GO:0043005	Component	Neuron projection	IBA
GO:0043025	Component	Neuronal cell body	IBA
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	10644755
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	10644755
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	25038658
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	10230407
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	10644755, 20347421
GO:0045862	Process	Positive regulation of proteolysis	IEA
GO:0045862	Process	Positive regulation of proteolysis	IMP	16885022
GO:0045893	Process	Positive regulation of DNA-templated transcription	ISS
GO:0046983	Function	Protein dimerization activity	IEA
GO:0047496	Process	Vesicle transport along microtubule	IBA
GO:0048511	Process	Rhythmic process	IEA
GO:0048854	Process	Brain morphogenesis	IBA
GO:0051010	Function	Microtubule plus-end binding	IBA
GO:0070840	Function	Dynein complex binding	IBA
GO:1904115	Component	Axon cytoplasm	IEA
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IDA	10321728, 10644755, 22017875, 22017876, 36608670
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IEA

Other IDs

• MIM: 605651
• HGNC: 13607
• e!Ensembl: ENSG00000072803

Protein

• UniProt ID: Q9UKB1
• Protein name: F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
• Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:10437795, PubMed:10648623, PubMed:11158290
• PDB: 6WNX
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12125	Beta-TrCP_D	78 → 116	D domain of beta-TrCP	Domain
  PF12937	F-box-like	120 → 170	F-box-like	Domain
  PF00400	WD40	228 → 266	WD domain, G-beta repeat	Repeat
  PF00400	WD40	270 → 306	WD domain, G-beta repeat	Repeat
  PF00400	WD40	310 → 346	WD domain, G-beta repeat	Repeat
  PF00400	WD40	353 → 389	WD domain, G-beta repeat	Repeat
  PF00400	WD40	393 → 429	WD domain, G-beta repeat	Repeat
  PF00400	WD40	433 → 469	WD domain, G-beta repeat	Repeat
  PF00400	WD40	483 → 518	WD domain, G-beta repeat	Repeat

• Sequence:

  MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVS
  RKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFI
  TALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKG
  LSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENS
  KGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDS
  TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLV
  GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGS
  SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPA
  STLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYI
  SR

• Sequence length: 542

Pathways

KEGG:

Oocyte meiosis
Ubiquitin mediated proteolysis
Cellular senescence
Wnt signaling pathway
Hedgehog signaling pathway
Hippo signaling pathway
Circadian rhythm
Shigellosis
Human immunodeficiency virus 1 infection

Reactome:

Activation of NF-kappaB in B cells
Downstream TCR signaling
Regulation of PLK1 Activity at G2/M Transition
FCERI mediated NF-kB activation
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
NIK-->noncanonical NF-kB signaling
MAP3K8 (TPL2)-dependent MAPK1/3 activation
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Neurodevelopmental, jaw, eye, and digital syndrome	Likely pathogenic; Pathogenic	rs1757708758, rs2113754835, rs2113777419, rs1758081491, rs1759346639	RCV001374430 RCV001374429 RCV001374428 RCV001374427 RCV001175173 RCV001175174	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FBXW11-related disorder	Uncertain significance; Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FBXW11-related neurodevelopmental, brain, eye, and digit anomalies	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet, Orphanet Disgenet, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	26845116		★☆☆☆☆ Found in Text Mining only
Adenomatous Polyposis Coli	Multiple polyposis syndrome	BEFREE	17510365		★☆☆☆☆ Found in Text Mining only
Atypical Teratoid Rhabdoid Tumor	Teratoid Rhabdoid Tumor	BEFREE	23816608		★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	8262676		★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	31832017		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	31832017		★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	Pubtator	36404534	Inhibit	★☆☆☆☆ Found in Text Mining only
Cleidocranial Dysplasia	Cleidocranial dysplasia	Pubtator	37199076	Stimulate	★☆☆☆☆ Found in Text Mining only
Epithelioma	Epithelioma	BEFREE	8262676		★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	9425296		★☆☆☆☆ Found in Text Mining only
Ewings sarcoma	Ewing sarcoma	BEFREE	12220726		★☆☆☆☆ Found in Text Mining only
Fibrosarcoma	Fibrosarcoma	BEFREE	24676544		★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	GENOMICS_ENGLAND_DG	31402090		★☆☆☆☆ Found in Text Mining only
Holoprosencephaly	Holoprosencephaly	BEFREE	16865294		★☆☆☆☆ Found in Text Mining only
Holoprosencephaly	Holoprosencephaly	LHGDN	16865294		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	34251416	Associate	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	GENOMICS_ENGLAND_DG	31402090		★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	29555946		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	23898085, 24222167		★☆☆☆☆ Found in Text Mining only
Lymphoid leukemia	Lymphoid leukemia	BEFREE	29555946		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	21665377		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	28473879, 29019495, 31218831, 31277454, 9639407		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	31832017		★☆☆☆☆ Found in Text Mining only
Microcephaly with Mental Retardation and Digital Anomalies	Microcephaly	Pubtator	31402090	Associate	★☆☆☆☆ Found in Text Mining only
Microphthalmia Syndromic 6	Microphthalmia	Pubtator	31402090	Associate	★☆☆☆☆ Found in Text Mining only
Myeloid Leukemia	Myeloid Leukemia	BEFREE	9201704		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12850370, 21717192, 22948234, 23315976, 24078465, 24803022, 28751246, 30132552		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	23816608, 25559288		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	27664533, 29736206, 30195702		★☆☆☆☆ Found in Text Mining only
Non-specific syndromic intellectual disability	Syndromic Mental Retardation	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Noonan Syndrome	Noonan syndrome	Pubtator	31402090	Associate	★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	10854558, 11089884, 11948684, 12220726, 12529988, 12850370, 1423871, 14534726, 15345332, 19623575, 2036957, 21460855, 21637161, 21822121, 22849560, 23315976, 23322324, 24229684, 24447333, 2450880, 24577130, 24803022, 24993351, 25394505, 25627547, 26339351, 26498360, 27310302, 27447864, 27684494, 27930982, 28128919, 28204978, 28281638, 28390115, 28393220, 28551767, 28618955, 28891632, 29019495, 29048645, 29048647, 29048662, 29363721, 29619662, 29654165, 29672299, 29693191, 29845265, 29879092, 30008875, 30013663, 30094957, 30106429, 30132552, 30248086, 30273544, 30317613, 30520540, 30761524, 31114984, 31218831, 31524248, 31564904, 3164526, 31770037, 8262676, 8992882		★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	37199076	Associate	★☆☆☆☆ Found in Text Mining only
Polydactyly	Polydactyly	BEFREE	16865294		★☆☆☆☆ Found in Text Mining only
Polydactyly	Polydactyly	LHGDN	16865294		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	21665377		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	16651270	Associate	★☆☆☆☆ Found in Text Mining only
Radial polydactyly	Radial Polydactyly	BEFREE	16865294		★☆☆☆☆ Found in Text Mining only
Retinoblastoma	Retinoblastoma	BEFREE	15538723		★☆☆☆☆ Found in Text Mining only
Small cell carcinoma of lung	Lung carcinoma	BEFREE	24327519		★☆☆☆☆ Found in Text Mining only