IQCE (IQ motif containing E)

Gene

• Entrez ID: 23288
• Gene name: IQ motif containing E
• Gene symbol: IQCE
• Synonyms (NCBI Gene): 1700028P05Rik, PAPA7
• Chromosome: 7
• Chromosome location: 7p22.3

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs753670589	C>T	Likely-pathogenic	Stop gained, coding sequence variant
rs755938967	G>A	Pathogenic	Genic upstream transcript variant, splice acceptor variant
rs760694987	AGAG>-	Pathogenic	Coding sequence variant, splice acceptor variant
rs773701437	CGGAGTGTCC>-	Pathogenic	Coding sequence variant, frameshift variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019831	hsa-miR-375	Microarray	20215506
MIRT022512	hsa-miR-124-3p	Microarray	18668037
MIRT046936	hsa-miR-221-3p	CLASH	23622248
MIRT644067	hsa-miR-4457	HITS-CLIP	23824327
MIRT644066	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT644065	hsa-miR-4469	HITS-CLIP	23824327
MIRT644064	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT644063	hsa-miR-4287	HITS-CLIP	23824327
MIRT644062	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT644061	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT644060	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT644059	hsa-miR-513b-5p	HITS-CLIP	23824327
MIRT644058	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT644057	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT644056	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT644067	hsa-miR-4457	HITS-CLIP	23824327
MIRT644066	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT644065	hsa-miR-4469	HITS-CLIP	23824327
MIRT644064	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT644063	hsa-miR-4287	HITS-CLIP	23824327
MIRT644062	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT644061	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT644060	hsa-miR-2467-3p	HITS-CLIP	23824327
MIRT644059	hsa-miR-513b-5p	HITS-CLIP	23824327
MIRT644058	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT644057	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT644056	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT1069555	hsa-miR-1197	CLIP-seq
MIRT1069556	hsa-miR-1200	CLIP-seq
MIRT1069557	hsa-miR-1255a	CLIP-seq
MIRT1069558	hsa-miR-1255b	CLIP-seq
MIRT1069559	hsa-miR-1267	CLIP-seq
MIRT1069560	hsa-miR-1273d	CLIP-seq
MIRT1069561	hsa-miR-1286	CLIP-seq
MIRT1069562	hsa-miR-1324	CLIP-seq
MIRT1069563	hsa-miR-136	CLIP-seq
MIRT1069564	hsa-miR-1587	CLIP-seq
MIRT1069565	hsa-miR-1909	CLIP-seq
MIRT1069566	hsa-miR-193a-5p	CLIP-seq
MIRT1069567	hsa-miR-1976	CLIP-seq
MIRT1069568	hsa-miR-214	CLIP-seq
MIRT1069569	hsa-miR-219-1-3p	CLIP-seq
MIRT1069570	hsa-miR-2277-3p	CLIP-seq
MIRT1069571	hsa-miR-23a	CLIP-seq
MIRT1069572	hsa-miR-23b	CLIP-seq
MIRT1069573	hsa-miR-23c	CLIP-seq
MIRT1069574	hsa-miR-3140-3p	CLIP-seq
MIRT1069575	hsa-miR-3157-5p	CLIP-seq
MIRT1069576	hsa-miR-3619-5p	CLIP-seq
MIRT1069577	hsa-miR-3690	CLIP-seq
MIRT1069578	hsa-miR-378g	CLIP-seq
MIRT1069579	hsa-miR-3944-5p	CLIP-seq
MIRT1069580	hsa-miR-4254	CLIP-seq
MIRT1069581	hsa-miR-4259	CLIP-seq
MIRT1069582	hsa-miR-4291	CLIP-seq
MIRT1069583	hsa-miR-4324	CLIP-seq
MIRT1069584	hsa-miR-4329	CLIP-seq
MIRT1069585	hsa-miR-4436a	CLIP-seq
MIRT1069586	hsa-miR-4468	CLIP-seq
MIRT1069587	hsa-miR-4477b	CLIP-seq
MIRT1069588	hsa-miR-4492	CLIP-seq
MIRT1069589	hsa-miR-4498	CLIP-seq
MIRT1069590	hsa-miR-4519	CLIP-seq
MIRT1069591	hsa-miR-4645-3p	CLIP-seq
MIRT1069592	hsa-miR-4652-3p	CLIP-seq
MIRT1069593	hsa-miR-4656	CLIP-seq
MIRT1069594	hsa-miR-4675	CLIP-seq
MIRT1069595	hsa-miR-4687-5p	CLIP-seq
MIRT1069596	hsa-miR-4690-3p	CLIP-seq
MIRT1069597	hsa-miR-4703-3p	CLIP-seq
MIRT1069598	hsa-miR-4715-5p	CLIP-seq
MIRT1069599	hsa-miR-4741	CLIP-seq
MIRT1069600	hsa-miR-4777-5p	CLIP-seq
MIRT1069601	hsa-miR-4793-5p	CLIP-seq
MIRT1069602	hsa-miR-544b	CLIP-seq
MIRT1069603	hsa-miR-571	CLIP-seq
MIRT1069604	hsa-miR-601	CLIP-seq
MIRT1069605	hsa-miR-661	CLIP-seq
MIRT1069606	hsa-miR-761	CLIP-seq
MIRT1069607	hsa-miR-762	CLIP-seq
MIRT1069608	hsa-miR-922	CLIP-seq
MIRT1069609	hsa-miR-1182	CLIP-seq
MIRT1069610	hsa-miR-1226	CLIP-seq
MIRT1069611	hsa-miR-1228	CLIP-seq
MIRT1069612	hsa-miR-1275	CLIP-seq
MIRT1069613	hsa-miR-182	CLIP-seq
MIRT1069614	hsa-miR-2110	CLIP-seq
MIRT1069615	hsa-miR-22	CLIP-seq
MIRT1069616	hsa-miR-24	CLIP-seq
MIRT1069617	hsa-miR-299-5p	CLIP-seq
MIRT1069618	hsa-miR-3064-3p	CLIP-seq
MIRT1069619	hsa-miR-3121-3p	CLIP-seq
MIRT1069620	hsa-miR-3144-5p	CLIP-seq
MIRT1069621	hsa-miR-3148	CLIP-seq
MIRT1069622	hsa-miR-3150a-3p	CLIP-seq
MIRT1069623	hsa-miR-3156-5p	CLIP-seq
MIRT1069624	hsa-miR-3177-3p	CLIP-seq
MIRT1069625	hsa-miR-3191	CLIP-seq
MIRT1069626	hsa-miR-342-3p	CLIP-seq
MIRT1069627	hsa-miR-3649	CLIP-seq
MIRT1069628	hsa-miR-3661	CLIP-seq
MIRT1069629	hsa-miR-3688-3p	CLIP-seq
MIRT1069630	hsa-miR-3689a-3p	CLIP-seq
MIRT1069631	hsa-miR-3689c	CLIP-seq
MIRT1069577	hsa-miR-3690	CLIP-seq
MIRT1069632	hsa-miR-3924	CLIP-seq
MIRT1069633	hsa-miR-3925-5p	CLIP-seq
MIRT1069580	hsa-miR-4254	CLIP-seq
MIRT1069634	hsa-miR-4260	CLIP-seq
MIRT1069635	hsa-miR-4264	CLIP-seq
MIRT1069636	hsa-miR-4271	CLIP-seq
MIRT1069637	hsa-miR-4284	CLIP-seq
MIRT1069638	hsa-miR-4300	CLIP-seq
MIRT1069639	hsa-miR-4433	CLIP-seq
MIRT1069640	hsa-miR-4455	CLIP-seq
MIRT1069641	hsa-miR-4459	CLIP-seq
MIRT1069642	hsa-miR-4474-5p	CLIP-seq
MIRT1069643	hsa-miR-4525	CLIP-seq
MIRT1069644	hsa-miR-4643	CLIP-seq
MIRT1069645	hsa-miR-4652-5p	CLIP-seq
MIRT1069646	hsa-miR-4665-5p	CLIP-seq
MIRT1069647	hsa-miR-4691-3p	CLIP-seq
MIRT1069648	hsa-miR-4694-3p	CLIP-seq
MIRT1069649	hsa-miR-4704-3p	CLIP-seq
MIRT1069650	hsa-miR-4713-5p	CLIP-seq
MIRT1069651	hsa-miR-4723-5p	CLIP-seq
MIRT1069652	hsa-miR-4725-3p	CLIP-seq
MIRT1069653	hsa-miR-4733-3p	CLIP-seq
MIRT1069654	hsa-miR-4768-3p	CLIP-seq
MIRT1069601	hsa-miR-4793-5p	CLIP-seq
MIRT1069655	hsa-miR-4797-3p	CLIP-seq
MIRT1069656	hsa-miR-492	CLIP-seq
MIRT1069657	hsa-miR-570	CLIP-seq
MIRT1069658	hsa-miR-579	CLIP-seq
MIRT1069659	hsa-miR-609	CLIP-seq
MIRT1069660	hsa-miR-625	CLIP-seq
MIRT1069661	hsa-miR-631	CLIP-seq
MIRT1069662	hsa-miR-646	CLIP-seq
MIRT1069663	hsa-miR-668	CLIP-seq
MIRT1069664	hsa-miR-671-5p	CLIP-seq
MIRT1069665	hsa-miR-920	CLIP-seq
MIRT2017096	hsa-miR-1202	CLIP-seq
MIRT1069610	hsa-miR-1226	CLIP-seq
MIRT2017097	hsa-miR-1236	CLIP-seq
MIRT2017098	hsa-miR-1254	CLIP-seq
MIRT2017099	hsa-miR-1302	CLIP-seq
MIRT1069564	hsa-miR-1587	CLIP-seq
MIRT1069568	hsa-miR-214	CLIP-seq
MIRT1069616	hsa-miR-24	CLIP-seq
MIRT2017100	hsa-miR-3116	CLIP-seq
MIRT2017101	hsa-miR-3122	CLIP-seq
MIRT2017102	hsa-miR-3130-3p	CLIP-seq
MIRT1069575	hsa-miR-3157-5p	CLIP-seq
MIRT2017103	hsa-miR-3173-5p	CLIP-seq
MIRT2017104	hsa-miR-3176	CLIP-seq
MIRT1069624	hsa-miR-3177-3p	CLIP-seq
MIRT2017105	hsa-miR-3189-3p	CLIP-seq
MIRT2017106	hsa-miR-3194-5p	CLIP-seq
MIRT2017107	hsa-miR-331-5p	CLIP-seq
MIRT2017108	hsa-miR-346	CLIP-seq
MIRT1069576	hsa-miR-3619-5p	CLIP-seq
MIRT2017109	hsa-miR-3647-3p	CLIP-seq
MIRT2017110	hsa-miR-3650	CLIP-seq
MIRT2017111	hsa-miR-3667-3p	CLIP-seq
MIRT1069630	hsa-miR-3689a-3p	CLIP-seq
MIRT1069631	hsa-miR-3689c	CLIP-seq
MIRT2017112	hsa-miR-370	CLIP-seq
MIRT1069578	hsa-miR-378g	CLIP-seq
MIRT2017113	hsa-miR-3913-5p	CLIP-seq
MIRT2017114	hsa-miR-3922-3p	CLIP-seq
MIRT1069632	hsa-miR-3924	CLIP-seq
MIRT2017115	hsa-miR-3972	CLIP-seq
MIRT1069637	hsa-miR-4284	CLIP-seq
MIRT2017116	hsa-miR-4288	CLIP-seq
MIRT1069582	hsa-miR-4291	CLIP-seq
MIRT2017117	hsa-miR-4298	CLIP-seq
MIRT1069638	hsa-miR-4300	CLIP-seq
MIRT2017118	hsa-miR-4311	CLIP-seq
MIRT2017119	hsa-miR-4418	CLIP-seq
MIRT2017120	hsa-miR-4453	CLIP-seq
MIRT1069640	hsa-miR-4455	CLIP-seq
MIRT1069586	hsa-miR-4468	CLIP-seq
MIRT1069588	hsa-miR-4492	CLIP-seq
MIRT1069589	hsa-miR-4498	CLIP-seq
MIRT1069590	hsa-miR-4519	CLIP-seq
MIRT2017121	hsa-miR-4530	CLIP-seq
MIRT2017122	hsa-miR-4538	CLIP-seq
MIRT2017123	hsa-miR-4640-5p	CLIP-seq
MIRT1069645	hsa-miR-4652-5p	CLIP-seq
MIRT1069593	hsa-miR-4656	CLIP-seq
MIRT2017124	hsa-miR-4663	CLIP-seq
MIRT2017125	hsa-miR-4667-3p	CLIP-seq
MIRT2017126	hsa-miR-4668-3p	CLIP-seq
MIRT1069594	hsa-miR-4675	CLIP-seq
MIRT2017127	hsa-miR-4678	CLIP-seq
MIRT1069596	hsa-miR-4690-3p	CLIP-seq
MIRT2017128	hsa-miR-4690-5p	CLIP-seq
MIRT1069647	hsa-miR-4691-3p	CLIP-seq
MIRT2017129	hsa-miR-4694-5p	CLIP-seq
MIRT2017130	hsa-miR-4698	CLIP-seq
MIRT2017131	hsa-miR-4711-3p	CLIP-seq
MIRT2017132	hsa-miR-4722-3p	CLIP-seq
MIRT2017133	hsa-miR-4726-5p	CLIP-seq
MIRT2017134	hsa-miR-4728-3p	CLIP-seq
MIRT2017135	hsa-miR-4731-3p	CLIP-seq
MIRT2017136	hsa-miR-4731-5p	CLIP-seq
MIRT1069599	hsa-miR-4741	CLIP-seq
MIRT2017137	hsa-miR-4747-3p	CLIP-seq
MIRT2017138	hsa-miR-4781-5p	CLIP-seq
MIRT2017139	hsa-miR-4799-5p	CLIP-seq
MIRT2017140	hsa-miR-4801	CLIP-seq
MIRT2017141	hsa-miR-509-3-5p	CLIP-seq
MIRT2017142	hsa-miR-509-5p	CLIP-seq
MIRT2017143	hsa-miR-539	CLIP-seq
MIRT2017144	hsa-miR-548aa	CLIP-seq
MIRT2017145	hsa-miR-562	CLIP-seq
MIRT1069657	hsa-miR-570	CLIP-seq
MIRT2017146	hsa-miR-580	CLIP-seq
MIRT2017147	hsa-miR-632	CLIP-seq
MIRT1069605	hsa-miR-661	CLIP-seq
MIRT1069606	hsa-miR-761	CLIP-seq
MIRT1069607	hsa-miR-762	CLIP-seq
MIRT2017148	hsa-miR-892b	CLIP-seq
MIRT1069665	hsa-miR-920	CLIP-seq
MIRT1069608	hsa-miR-922	CLIP-seq
MIRT2249102	hsa-miR-1184	CLIP-seq
MIRT2249103	hsa-miR-1205	CLIP-seq
MIRT2249104	hsa-miR-1291	CLIP-seq
MIRT2249105	hsa-miR-3158-5p	CLIP-seq
MIRT2249106	hsa-miR-3160-5p	CLIP-seq
MIRT2249107	hsa-miR-3665	CLIP-seq
MIRT1069645	hsa-miR-4652-5p	CLIP-seq
MIRT2249108	hsa-miR-544	CLIP-seq
MIRT2249109	hsa-miR-657	CLIP-seq
MIRT2249102	hsa-miR-1184	CLIP-seq
MIRT2389451	hsa-miR-140-3p	CLIP-seq
MIRT2389452	hsa-miR-298	CLIP-seq
MIRT2389453	hsa-miR-3151	CLIP-seq
MIRT2249105	hsa-miR-3158-5p	CLIP-seq
MIRT2552686	hsa-miR-1207-3p	CLIP-seq
MIRT2552687	hsa-miR-138	CLIP-seq
MIRT2552688	hsa-miR-4267	CLIP-seq
MIRT2552689	hsa-miR-4290	CLIP-seq
MIRT2017124	hsa-miR-4663	CLIP-seq
MIRT2552690	hsa-miR-548q	CLIP-seq
MIRT2552691	hsa-miR-766	CLIP-seq
MIRT2552686	hsa-miR-1207-3p	CLIP-seq
MIRT2552687	hsa-miR-138	CLIP-seq
MIRT2552688	hsa-miR-4267	CLIP-seq
MIRT2552689	hsa-miR-4290	CLIP-seq
MIRT2017124	hsa-miR-4663	CLIP-seq
MIRT2552690	hsa-miR-548q	CLIP-seq
MIRT2552691	hsa-miR-766	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	24722188, 25416956, 32296183, 33961781
GO:0005886	Component	Plasma membrane	IEA
GO:0005929	Component	Cilium	IEA
GO:0005929	Component	Cilium	TAS
GO:0016020	Component	Membrane	IEA
GO:0035108	Process	Limb morphogenesis	IMP	28488682
GO:0042995	Component	Cell projection	IEA
GO:0060170	Component	Ciliary membrane	IEA

Other IDs

• MIM: 617631
• HGNC: 29171
• e!Ensembl: ENSG00000106012

Protein

• UniProt ID: Q6IPM2
• Protein name: IQ domain-containing protein E
• Protein function: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (By similarity). Required for proper limb morphogenesis (PubMed:28488682).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00612	IQ	543 → 563	IQ calmodulin-binding motif	Motif
  PF00612	IQ	602 → 622	IQ calmodulin-binding motif	Motif

• Sequence:

  MFLGTGEPALDTGDDSLSAVTFDSDVETKAKRKAFHKPPPTSPKSPYLSKPRKVASWRSL
  RTAGSMPLGGRASLTPQKLWLGTAKPGSLTQALNSPLTWEHAWTGVPGGTPDCLTDTFRV
  KRPHLRRSASNGHVPGTPVYREKEDMYDEIIELKKSLHVQKSDVDLMRTKLRRLEEENSR
  KDRQIEQLLDPSRGTDFVRTLAEKRPDASWVINGLKQRILKLEQQCKEKDGTISKLQTDM
  KTTNLEEMRIAMETYYEEVHRLQTLLASSETTGKKPLGEKKTGAKRQKKMGSALLSLSRS
  VQELTEENQSLKEDLDRVLSTSPTISKTQGYVEWSKPRLLRRIVELEKKLSVMESSKSHA
  AEPVRSHPPACLASSSALHRQPRGDRNKDHERLRGAVRDLKEERTALQEQLLQRDLEVKQ
  LLQAKADLEKELECAREGEEERREREEVLREEIQTLTSKLQELQEMKKEEKEDCPEVPHK
  AQELPAPTPSSRHCEQDWPPDSSEEGLPRPRSPCSDGRRDAAARVLQAQWKVYKHKKKKA
  VLDEAAVVLQAAFRGHLTRTKLLASKAHGSEPPSVPGLPDQSSPVPRVPSPIAQATGSPV
  QEEAIVIIQSALRAHLARARHSATGKRTTTAASTRRRSASATHGDASSPPFLAALPDPSP
  SGPQALAPLPGDDVNSDDSDDIVIAPSLPTKNFPV

• Sequence length: 695

Pathways

KEGG:

Hedgehog signaling pathway

Reactome:

Activation of SMO

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Familial pancreatic carcinoma	Pathogenic	rs760694987	RCV005870878	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
IQCE-related disorder	Pathogenic	rs760694987	RCV003413586	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Polydactyly, postaxial, type A1	Pathogenic	rs760694987	RCV000852375	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Polydactyly, postaxial, type a7	Likely pathogenic; Pathogenic	rs1298717770, rs759821884, rs755938967, rs760694987	RCV001331779 RCV003990936 RCV000500395 RCV001255655	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANXIETY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Brachydactyly	Conflicting classifications of pathogenicity	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Clear cell carcinoma of kidney	Uncertain significance; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal cancer	Uncertain significance; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERALDOSTERONISM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANIC DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POSTAXIAL POLYDACTYLY TYPE A	—	Disgenet, HPO Disgenet, HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Retinal degeneration	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Syndactyly	Conflicting classifications of pathogenicity	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Thyroid cancer, nonmedullary, 1	Uncertain significance; Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Amyotrophic lateral sclerosis 1	Amyotrophic lateral sclerosis	Pubtator	35853630	Associate	★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	32462000	Associate	★☆☆☆☆ Found in Text Mining only
Multiple congenital anomalies	Multiple Congenital Anomalies	CLINVAR_DG	18799693, 19810119, 22495311, 22981989, 23719536, 24582806, 25348401, 27626380, 28224613, 28488682, 3719536, 9399901		★☆☆☆☆ Found in Text Mining only
Polydactyly	Polydactyly	BEFREE	28488682		★☆☆☆☆ Found in Text Mining only
Polydactyly	Polydactyly	Pubtator	28488682	Associate	★☆☆☆☆ Found in Text Mining only
Polydactyly Postaxial	Polydactyly	Pubtator	37684519	Associate	★☆☆☆☆ Found in Text Mining only
POLYDACTYLY, POSTAXIAL	Polydactyly	BEFREE	31549751		★☆☆☆☆ Found in Text Mining only
POLYDACTYLY, POSTAXIAL	Polydactyly	HPO_DG			★☆☆☆☆ Found in Text Mining only
POLYDACTYLY, POSTAXIAL, TYPE A7	Polydactyly	GENOMICS_ENGLAND_DG	28488682		★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Postaxial polydactyly type A	Polydactyly	ORPHANET_DG	26394607, 28488682		★★☆☆☆ Found in Text Mining + Unknown/Other Associations