Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23271
Gene name	Calmodulin regulated spectrin associated protein family member 2
Gene symbol	CAMSAP2
Synonyms (NCBI Gene)	CAMSAP1L1
Chromosome	1
Chromosome location	1q32.1

153

Show/Hide all (153)

miRTarBase ID	miRNA	Experiments	Reference
MIRT021864	hsa-miR-132-3p	Microarray	17612493
MIRT507896	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT507895	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT507894	hsa-miR-548n	PAR-CLIP	21572407
MIRT507893	hsa-miR-6768-3p	PAR-CLIP	21572407
MIRT507892	hsa-miR-548av-5p	PAR-CLIP	21572407
MIRT507891	hsa-miR-548k	PAR-CLIP	21572407
MIRT507890	hsa-miR-8054	PAR-CLIP	21572407
MIRT507888	hsa-miR-6854-5p	PAR-CLIP	21572407
MIRT507889	hsa-miR-1245b-5p	PAR-CLIP	21572407
MIRT507887	hsa-miR-3142	PAR-CLIP	21572407
MIRT507886	hsa-miR-369-3p	PAR-CLIP	21572407
MIRT507885	hsa-miR-5692b	PAR-CLIP	21572407
MIRT507884	hsa-miR-5692c	PAR-CLIP	21572407
MIRT558963	hsa-miR-211-3p	PAR-CLIP	21572407
MIRT558962	hsa-miR-4270	PAR-CLIP	21572407
MIRT558960	hsa-miR-4441	PAR-CLIP	21572407
MIRT558961	hsa-miR-6754-5p	PAR-CLIP	21572407
MIRT558959	hsa-miR-1266-5p	PAR-CLIP	21572407
MIRT558958	hsa-miR-4518	PAR-CLIP	21572407
MIRT507883	hsa-miR-3934-3p	PAR-CLIP	21572407
MIRT549054	hsa-miR-3121-3p	PAR-CLIP	21572407
MIRT549053	hsa-miR-8084	PAR-CLIP	21572407
MIRT549052	hsa-miR-200b-3p	PAR-CLIP	21572407
MIRT549051	hsa-miR-200c-3p	PAR-CLIP	21572407
MIRT549050	hsa-miR-429	PAR-CLIP	21572407
MIRT549049	hsa-miR-374c-3p	PAR-CLIP	21572407
MIRT549048	hsa-miR-1236-5p	PAR-CLIP	21572407
MIRT549047	hsa-miR-4765	PAR-CLIP	21572407
MIRT549046	hsa-miR-374c-5p	PAR-CLIP	21572407
MIRT549045	hsa-miR-655-3p	PAR-CLIP	21572407
MIRT549044	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT549043	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT549042	hsa-miR-4658	PAR-CLIP	21572407
MIRT549041	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT507896	hsa-miR-374b-5p	PAR-CLIP	23446348
MIRT507895	hsa-miR-374a-5p	PAR-CLIP	23446348
MIRT507894	hsa-miR-548n	PAR-CLIP	23446348
MIRT507893	hsa-miR-6768-3p	PAR-CLIP	23446348
MIRT507892	hsa-miR-548av-5p	PAR-CLIP	23446348
MIRT507891	hsa-miR-548k	PAR-CLIP	23446348
MIRT507890	hsa-miR-8054	PAR-CLIP	23446348
MIRT507888	hsa-miR-6854-5p	PAR-CLIP	23446348
MIRT507889	hsa-miR-1245b-5p	PAR-CLIP	23446348
MIRT507887	hsa-miR-3142	PAR-CLIP	23446348
MIRT507886	hsa-miR-369-3p	PAR-CLIP	23446348
MIRT507885	hsa-miR-5692b	PAR-CLIP	23446348
MIRT507884	hsa-miR-5692c	PAR-CLIP	23446348
MIRT507883	hsa-miR-3934-3p	PAR-CLIP	23446348
MIRT503055	hsa-miR-19b-3p	PAR-CLIP	24398324
MIRT503054	hsa-miR-19a-3p	PAR-CLIP	24398324
MIRT503053	hsa-miR-4295	PAR-CLIP	24398324
MIRT503052	hsa-miR-454-3p	PAR-CLIP	24398324
MIRT503051	hsa-miR-3666	PAR-CLIP	24398324
MIRT503050	hsa-miR-301a-3p	PAR-CLIP	24398324
MIRT503049	hsa-miR-130b-3p	PAR-CLIP	24398324
MIRT503048	hsa-miR-130a-3p	PAR-CLIP	24398324
MIRT503047	hsa-miR-301b-3p	PAR-CLIP	24398324
MIRT503046	hsa-miR-519a-3p	PAR-CLIP	24398324
MIRT503045	hsa-miR-519b-3p	PAR-CLIP	24398324
MIRT503044	hsa-miR-519c-3p	PAR-CLIP	24398324
MIRT503043	hsa-miR-1910-3p	PAR-CLIP	24398324
MIRT503042	hsa-miR-6511a-5p	PAR-CLIP	24398324
MIRT503041	hsa-miR-6808-5p	PAR-CLIP	24398324
MIRT503040	hsa-miR-6893-5p	PAR-CLIP	24398324
MIRT503039	hsa-miR-940	PAR-CLIP	24398324
MIRT503038	hsa-miR-2682-5p	PAR-CLIP	24398324
MIRT503037	hsa-miR-34b-5p	PAR-CLIP	24398324
MIRT503036	hsa-miR-449c-5p	PAR-CLIP	24398324
MIRT503035	hsa-miR-1295b-3p	PAR-CLIP	24398324
MIRT503034	hsa-miR-4795-5p	PAR-CLIP	24398324
MIRT503033	hsa-miR-873-5p	PAR-CLIP	24398324
MIRT503032	hsa-miR-3616-5p	PAR-CLIP	24398324
MIRT503031	hsa-miR-573	PAR-CLIP	24398324
MIRT503030	hsa-miR-7159-3p	PAR-CLIP	24398324
MIRT503029	hsa-miR-4482-3p	PAR-CLIP	24398324
MIRT503054	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT503055	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT507896	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT507895	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT507894	hsa-miR-548n	PAR-CLIP	21572407
MIRT507893	hsa-miR-6768-3p	PAR-CLIP	21572407
MIRT507892	hsa-miR-548av-5p	PAR-CLIP	21572407
MIRT507891	hsa-miR-548k	PAR-CLIP	21572407
MIRT507890	hsa-miR-8054	PAR-CLIP	21572407
MIRT507888	hsa-miR-6854-5p	PAR-CLIP	21572407
MIRT507889	hsa-miR-1245b-5p	PAR-CLIP	21572407
MIRT507887	hsa-miR-3142	PAR-CLIP	21572407
MIRT507886	hsa-miR-369-3p	PAR-CLIP	21572407
MIRT507885	hsa-miR-5692b	PAR-CLIP	21572407
MIRT507884	hsa-miR-5692c	PAR-CLIP	21572407
MIRT558963	hsa-miR-211-3p	PAR-CLIP	21572407
MIRT558962	hsa-miR-4270	PAR-CLIP	21572407
MIRT558960	hsa-miR-4441	PAR-CLIP	21572407
MIRT558961	hsa-miR-6754-5p	PAR-CLIP	21572407
MIRT558959	hsa-miR-1266-5p	PAR-CLIP	21572407
MIRT558958	hsa-miR-4518	PAR-CLIP	21572407
MIRT507883	hsa-miR-3934-3p	PAR-CLIP	21572407
MIRT549054	hsa-miR-3121-3p	PAR-CLIP	21572407
MIRT549053	hsa-miR-8084	PAR-CLIP	21572407
MIRT549052	hsa-miR-200b-3p	PAR-CLIP	21572407
MIRT549051	hsa-miR-200c-3p	PAR-CLIP	21572407
MIRT549050	hsa-miR-429	PAR-CLIP	21572407
MIRT549049	hsa-miR-374c-3p	PAR-CLIP	21572407
MIRT549048	hsa-miR-1236-5p	PAR-CLIP	21572407
MIRT549047	hsa-miR-4765	PAR-CLIP	21572407
MIRT549046	hsa-miR-374c-5p	PAR-CLIP	21572407
MIRT549045	hsa-miR-655-3p	PAR-CLIP	21572407
MIRT549044	hsa-miR-1238-5p	PAR-CLIP	21572407
MIRT549043	hsa-miR-4758-5p	PAR-CLIP	21572407
MIRT549042	hsa-miR-4658	PAR-CLIP	21572407
MIRT549041	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT507896	hsa-miR-374b-5p	PAR-CLIP	23446348
MIRT507895	hsa-miR-374a-5p	PAR-CLIP	23446348
MIRT507894	hsa-miR-548n	PAR-CLIP	23446348
MIRT507893	hsa-miR-6768-3p	PAR-CLIP	23446348
MIRT507892	hsa-miR-548av-5p	PAR-CLIP	23446348
MIRT507891	hsa-miR-548k	PAR-CLIP	23446348
MIRT507890	hsa-miR-8054	PAR-CLIP	23446348
MIRT507888	hsa-miR-6854-5p	PAR-CLIP	23446348
MIRT507889	hsa-miR-1245b-5p	PAR-CLIP	23446348
MIRT507887	hsa-miR-3142	PAR-CLIP	23446348
MIRT507886	hsa-miR-369-3p	PAR-CLIP	23446348
MIRT507885	hsa-miR-5692b	PAR-CLIP	23446348
MIRT507884	hsa-miR-5692c	PAR-CLIP	23446348
MIRT507883	hsa-miR-3934-3p	PAR-CLIP	23446348
MIRT503055	hsa-miR-19b-3p	PAR-CLIP	24398324
MIRT503054	hsa-miR-19a-3p	PAR-CLIP	24398324
MIRT503053	hsa-miR-4295	PAR-CLIP	24398324
MIRT503052	hsa-miR-454-3p	PAR-CLIP	24398324
MIRT503051	hsa-miR-3666	PAR-CLIP	24398324
MIRT503050	hsa-miR-301a-3p	PAR-CLIP	24398324
MIRT503049	hsa-miR-130b-3p	PAR-CLIP	24398324
MIRT503048	hsa-miR-130a-3p	PAR-CLIP	24398324
MIRT503047	hsa-miR-301b-3p	PAR-CLIP	24398324
MIRT503046	hsa-miR-519a-3p	PAR-CLIP	24398324
MIRT503045	hsa-miR-519b-3p	PAR-CLIP	24398324
MIRT503044	hsa-miR-519c-3p	PAR-CLIP	24398324
MIRT503043	hsa-miR-1910-3p	PAR-CLIP	24398324
MIRT503042	hsa-miR-6511a-5p	PAR-CLIP	24398324
MIRT503041	hsa-miR-6808-5p	PAR-CLIP	24398324
MIRT503040	hsa-miR-6893-5p	PAR-CLIP	24398324
MIRT503039	hsa-miR-940	PAR-CLIP	24398324
MIRT503038	hsa-miR-2682-5p	PAR-CLIP	24398324
MIRT503037	hsa-miR-34b-5p	PAR-CLIP	24398324
MIRT503036	hsa-miR-449c-5p	PAR-CLIP	24398324
MIRT503035	hsa-miR-1295b-3p	PAR-CLIP	24398324
MIRT503034	hsa-miR-4795-5p	PAR-CLIP	24398324
MIRT503033	hsa-miR-873-5p	PAR-CLIP	24398324
MIRT503032	hsa-miR-3616-5p	PAR-CLIP	24398324
MIRT503031	hsa-miR-573	PAR-CLIP	24398324
MIRT503030	hsa-miR-7159-3p	PAR-CLIP	24398324
MIRT503029	hsa-miR-4482-3p	PAR-CLIP	24398324

Show/Hide all (34)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000226	Process	Microtubule cytoskeleton organization	IDA	24486153, 24706919, 24908486, 27666745
GO:0000226	Process	Microtubule cytoskeleton organization	IEA
GO:0000226	Process	Microtubule cytoskeleton organization	IMP	23169647
GO:0005515	Function	Protein binding	IPI	20195357, 24486153, 27666745
GO:0005516	Function	Calmodulin binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IDA	27666745
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005813	Component	Centrosome	IDA	23169647
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0007026	Process	Negative regulation of microtubule depolymerization	IBA
GO:0008017	Function	Microtubule binding	IEA
GO:0030507	Function	Spectrin binding	IEA
GO:0031113	Process	Regulation of microtubule polymerization	IDA	24486153, 24706919
GO:0031113	Process	Regulation of microtubule polymerization	IEA
GO:0031122	Process	Cytoplasmic microtubule organization	IBA
GO:0031175	Process	Neuron projection development	IEA
GO:0033043	Process	Regulation of organelle organization	IMP	23169647
GO:0036064	Component	Ciliary basal body	ISS
GO:0036449	Component	Microtubule minus-end	IBA
GO:0036449	Component	Microtubule minus-end	IDA	24486153, 24706919, 24908486
GO:0042995	Component	Cell projection	IEA
GO:0050773	Process	Regulation of dendrite development	IDA	24908486
GO:0050773	Process	Regulation of dendrite development	IEA
GO:0051011	Function	Microtubule minus-end binding	IBA
GO:0051011	Function	Microtubule minus-end binding	IDA	23169647, 24486153, 24706919, 24908486, 27666745
GO:0051011	Function	Microtubule minus-end binding	IEA
GO:0061564	Process	Axon development	IDA	24908486
GO:0061564	Process	Axon development	IEA
GO:1903358	Process	Regulation of Golgi organization	IDA	27666745
GO:1990752	Component	Microtubule end	IDA

MIM	HGNC	e!Ensembl
613775	29188	ENSG00000118200

Q08AD1

Protein name

Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1)

Protein function

Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:23169647, PubMed:24486153, PubMed:24706919). Specifically recognizes growing microtubu

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF11971	CAMSAP_CH	233 → 316	CAMSAP CH domain	Domain
PF17095	CAMSAP_CC1	749 → 804	Spectrin-binding region of Ca2+-Calmodulin	Family
PF08683	CAMSAP_CKK	1350 → 1468	Microtubule-binding calmodulin-regulated spectrin-associated	Domain

Sequence

MGDAADPREMRKTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTD
QYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAQKGLYVTDQEKL
VTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDA
VMYWINKVNEHLKDIMEQEQKLKEHHTVEAPGGQKSPSKWFWKLVPARYRKEQTLLKQLP
CIPLVENLLKDGTDGCALAALIHFYCPDVVRLEDICLKETMSLADSLYNLQLIQEFCQEY
LNQCCHFTLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEPVKDMPS
IPVLNAAKRNVLDSSSDFPSSGEGATFTQSHHHLPSRYSRPQAHSSASGGIRRSSSMSYV
DGFIGTWPKEKRSSVHGVSFDISFDKEDSVQRSTPNRGITRSISNEGLTLNNSHVSKHIR
KNLSFKPINGEEEAESIEEELNIDSHSDLKSCVPLNTNELNSNENIHYKLPNGALQNRIL
LDEFGNQIETPSIEEALQIIHDTEKSPHTPQPDQIANGFFLHSQEMSILNSNIKLNQSSP
DNVTDTKGALSPITDNTEVDTGIHVPSEDIPETMDEDSSLRDYTVSLDSDMDDASKFLQD
YDIRTGNTREALSPCPSTVSTKSQPGSSASSSSGVKMTSFAEQKFRKLNHTDGKSSGSSS
QKTTPEGSELNIPHVVAWAQIPEETGLPQGRDTTQLLASEMVHLRMKLEEKRRAIEAQKK
KMEAAFTKQRQKMGRTAFLTVVKKKGDGISPLREEAAGAEDEKVYTDRAKEKESQKTDGQ
RSKSLADIKESMENPQAKWLKSPTTPIDPEKQWNLASPSEETLNEGEILEYTKSIEKLNS
SLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKPSKQAGLSSAIAPFS
SDSPRPTHPSPQSSNRKSASFSVKSQRTPRPNELKITPLNRTLTPPRSVDSLPRLRRFSP
SQVPIQTRSFVCFGDDGEPQLKESKPKEEVKKEELESKGTLEQRGHNPEEKEIKPFESTV
SEVLSLPVTETVCLTPNEDQLNQPTEPPPKPVFPPTAPKNVNLIEVSLSDLKPPEKADVP
VEKYDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAMKRAALLEKRLRREKETQLRKQQL
EAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQVVK
QKKQRPKSIHRDHIESPKTPIKGPPVSSLSLASLNTGDNESVHSGKRTPRSESVEGFLSP
SRCGSRNGEKDWENASTTSSVASGTEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNE
GQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEG
LYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA

Sequence length

1489

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (16)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CELIAC DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EPILEPSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GENERALISED EPILEPSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPOTHYROIDISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARTIAL EPILEPSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Premature ovarian insufficiency	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 1 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (7)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Aneuploidy	Aneuploidy	Pubtator	39735979	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	GWASCAT_DG	25751624		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	22116939, 24148305		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epilepsy	Epilepsy	GWASCAT_DG	22116939		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epilepsy	Epilepsy	GWASDB_DG	22116939		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neuroblastoma	Neuroblastoma	BEFREE	24148305		★★★★★ ★☆☆☆☆ Found in Text Mining only

CAMSAP2 (calmodulin regulated spectrin associated protein family member 2)