EXOC7 (exocyst complex component 7)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23265 |
| Gene name | Exocyst complex component 7 |
| Gene symbol | EXOC7 |
| Synonyms (NCBI Gene) |
2-5-3pBLOM4EX070EXO70EXOC1Exo70pNEDSEBAYJL085W
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| Chromosome | 17 |
| Chromosome location | 17q25.1 |
| Summary | The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required f |
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miRNA
miRNA information provided by mirtarbase database.
252
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
29
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9UPT5 | ||||||||||
| Protein name | Exocyst complex component 7 (Exocyst complex component Exo70) | ||||||||||
| Protein function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps direct | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Abundant in the ventricular zone, the outer subventricular zone and the cortical plate of the fetal cortex. {ECO:0000269|PubMed:32103185}. | ||||||||||
| Sequence |
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| Sequence length | 735 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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