SIK2 (salt inducible kinase 2)

Gene

• Entrez ID: 23235
• Gene name: Salt inducible kinase 2
• Gene symbol: SIK2
• Synonyms (NCBI Gene): LOH11CR1I, QIK, SIK-2, SNF1LK2
• Chromosome: 11
• Chromosome location: 11q23.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT047302	hsa-miR-181a-5p	CLASH	23622248
MIRT045926	hsa-miR-125b-5p	CLASH	23622248
MIRT036375	hsa-miR-1229-3p	CLASH	23622248
MIRT679370	hsa-miR-4438	HITS-CLIP	23824327
MIRT679369	hsa-miR-4740-3p	HITS-CLIP	23824327
MIRT679368	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679367	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679366	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679365	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679364	hsa-miR-1976	HITS-CLIP	23824327
MIRT679362	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679363	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT679361	hsa-miR-5095	HITS-CLIP	23824327
MIRT679360	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT679359	hsa-miR-4279	HITS-CLIP	23824327
MIRT679370	hsa-miR-4438	HITS-CLIP	23824327
MIRT679369	hsa-miR-4740-3p	HITS-CLIP	23824327
MIRT679368	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679367	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679366	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679365	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679364	hsa-miR-1976	HITS-CLIP	23824327
MIRT679362	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679363	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT679361	hsa-miR-5095	HITS-CLIP	23824327
MIRT679360	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT679359	hsa-miR-4279	HITS-CLIP	23824327
MIRT672259	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT672258	hsa-miR-5693	HITS-CLIP	23824327
MIRT672257	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT672256	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT672255	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT672254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT672253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT672252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT672251	hsa-miR-564	HITS-CLIP	23824327
MIRT672250	hsa-miR-4284	HITS-CLIP	23824327
MIRT672249	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT672248	hsa-miR-3652	HITS-CLIP	23824327
MIRT672247	hsa-miR-4430	HITS-CLIP	23824327
MIRT672246	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT672245	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT672244	hsa-miR-8057	HITS-CLIP	23824327
MIRT672243	hsa-miR-5698	HITS-CLIP	23824327
MIRT630945	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT630944	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT630943	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT630942	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT630941	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT630940	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT630939	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT630938	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT495229	hsa-miR-4676-5p	PAR-CLIP	22291592
MIRT495228	hsa-miR-575	PAR-CLIP	22291592
MIRT495227	hsa-miR-4786-3p	PAR-CLIP	22291592
MIRT495229	hsa-miR-4676-5p	PAR-CLIP	23708386
MIRT495228	hsa-miR-575	PAR-CLIP	23708386
MIRT495227	hsa-miR-4786-3p	PAR-CLIP	23708386
MIRT439636	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT439637	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439636	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT439637	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT737090	hsa-miR-526b-5p	Luciferase reporter assay, Western blotting, qRT-PCR	33344445
MIRT679370	hsa-miR-4438	HITS-CLIP	23824327
MIRT679369	hsa-miR-4740-3p	HITS-CLIP	23824327
MIRT679368	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679367	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679366	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679365	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679364	hsa-miR-1976	HITS-CLIP	23824327
MIRT679362	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679363	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT679361	hsa-miR-5095	HITS-CLIP	23824327
MIRT679360	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT679359	hsa-miR-4279	HITS-CLIP	23824327
MIRT679370	hsa-miR-4438	HITS-CLIP	23824327
MIRT679369	hsa-miR-4740-3p	HITS-CLIP	23824327
MIRT679368	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679367	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679366	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679365	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679364	hsa-miR-1976	HITS-CLIP	23824327
MIRT679362	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679363	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT679361	hsa-miR-5095	HITS-CLIP	23824327
MIRT679360	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT679359	hsa-miR-4279	HITS-CLIP	23824327
MIRT672259	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT672258	hsa-miR-5693	HITS-CLIP	23824327
MIRT672257	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT672256	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT672255	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT672254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT672253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT672252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT672251	hsa-miR-564	HITS-CLIP	23824327
MIRT672250	hsa-miR-4284	HITS-CLIP	23824327
MIRT672249	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT672248	hsa-miR-3652	HITS-CLIP	23824327
MIRT672247	hsa-miR-4430	HITS-CLIP	23824327
MIRT672246	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT672245	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT672244	hsa-miR-8057	HITS-CLIP	23824327
MIRT672243	hsa-miR-5698	HITS-CLIP	23824327
MIRT630945	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT630944	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT630943	hsa-miR-4436b-5p	HITS-CLIP	23824327
MIRT630942	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT630941	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT630940	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT630939	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT630938	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT495229	hsa-miR-4676-5p	PAR-CLIP	22291592
MIRT495228	hsa-miR-575	PAR-CLIP	22291592
MIRT495227	hsa-miR-4786-3p	PAR-CLIP	22291592
MIRT495229	hsa-miR-4676-5p	PAR-CLIP	23708386
MIRT495228	hsa-miR-575	PAR-CLIP	23708386
MIRT495227	hsa-miR-4786-3p	PAR-CLIP	23708386
MIRT1348923	hsa-miR-103a	CLIP-seq
MIRT1348924	hsa-miR-107	CLIP-seq
MIRT1348925	hsa-miR-1200	CLIP-seq
MIRT1348926	hsa-miR-1288	CLIP-seq
MIRT1348927	hsa-miR-1289	CLIP-seq
MIRT1348928	hsa-miR-141	CLIP-seq
MIRT1348929	hsa-miR-15a	CLIP-seq
MIRT1348930	hsa-miR-15b	CLIP-seq
MIRT1348931	hsa-miR-16	CLIP-seq
MIRT1348932	hsa-miR-194	CLIP-seq
MIRT1348933	hsa-miR-195	CLIP-seq
MIRT1348934	hsa-miR-200a	CLIP-seq
MIRT1348935	hsa-miR-203	CLIP-seq
MIRT1348936	hsa-miR-2115	CLIP-seq
MIRT1348937	hsa-miR-2116	CLIP-seq
MIRT1348938	hsa-miR-219-2-3p	CLIP-seq
MIRT1348939	hsa-miR-2278	CLIP-seq
MIRT1348940	hsa-miR-2681	CLIP-seq
MIRT1348941	hsa-miR-2964a-3p	CLIP-seq
MIRT1348942	hsa-miR-3137	CLIP-seq
MIRT1348943	hsa-miR-3151	CLIP-seq
MIRT1348944	hsa-miR-3162-5p	CLIP-seq
MIRT1348945	hsa-miR-3176	CLIP-seq
MIRT1348946	hsa-miR-3198	CLIP-seq
MIRT1348947	hsa-miR-3199	CLIP-seq
MIRT1348948	hsa-miR-3591-3p	CLIP-seq
MIRT1348949	hsa-miR-3646	CLIP-seq
MIRT1348950	hsa-miR-3660	CLIP-seq
MIRT1348951	hsa-miR-3922-3p	CLIP-seq
MIRT1348952	hsa-miR-409-3p	CLIP-seq
MIRT1348953	hsa-miR-424	CLIP-seq
MIRT1348954	hsa-miR-4256	CLIP-seq
MIRT1348955	hsa-miR-4294	CLIP-seq
MIRT1348956	hsa-miR-4309	CLIP-seq
MIRT1348957	hsa-miR-4324	CLIP-seq
MIRT1348958	hsa-miR-4435	CLIP-seq
MIRT1348959	hsa-miR-4459	CLIP-seq
MIRT1348960	hsa-miR-4526	CLIP-seq
MIRT1348961	hsa-miR-4540	CLIP-seq
MIRT1348962	hsa-miR-4677-5p	CLIP-seq
MIRT1348963	hsa-miR-4711-5p	CLIP-seq
MIRT1348964	hsa-miR-4729	CLIP-seq
MIRT1348965	hsa-miR-4735-5p	CLIP-seq
MIRT1348966	hsa-miR-4777-5p	CLIP-seq
MIRT1348967	hsa-miR-4778-5p	CLIP-seq
MIRT1348968	hsa-miR-486-3p	CLIP-seq
MIRT1348969	hsa-miR-496	CLIP-seq
MIRT1348970	hsa-miR-497	CLIP-seq
MIRT1348971	hsa-miR-516b	CLIP-seq
MIRT1348972	hsa-miR-518d-5p	CLIP-seq
MIRT1348973	hsa-miR-519b-5p	CLIP-seq
MIRT1348974	hsa-miR-519c-5p	CLIP-seq
MIRT1348975	hsa-miR-520c-5p	CLIP-seq
MIRT1348976	hsa-miR-526a	CLIP-seq
MIRT1348977	hsa-miR-541	CLIP-seq
MIRT1348978	hsa-miR-544b	CLIP-seq
MIRT1348979	hsa-miR-548a-3p	CLIP-seq
MIRT1348980	hsa-miR-548e	CLIP-seq
MIRT1348981	hsa-miR-548f	CLIP-seq
MIRT1348982	hsa-miR-579	CLIP-seq
MIRT1348983	hsa-miR-582-5p	CLIP-seq
MIRT1348984	hsa-miR-595	CLIP-seq
MIRT1348985	hsa-miR-654-5p	CLIP-seq
MIRT1348986	hsa-miR-665	CLIP-seq
MIRT1348987	hsa-miR-671-5p	CLIP-seq
MIRT1348988	hsa-miR-767-3p	CLIP-seq
MIRT1348989	hsa-miR-935	CLIP-seq
MIRT1348925	hsa-miR-1200	CLIP-seq
MIRT2103386	hsa-miR-1270	CLIP-seq
MIRT2103387	hsa-miR-128	CLIP-seq
MIRT1348927	hsa-miR-1289	CLIP-seq
MIRT2103388	hsa-miR-1290	CLIP-seq
MIRT2103389	hsa-miR-1298	CLIP-seq
MIRT2103390	hsa-miR-1343	CLIP-seq
MIRT2103391	hsa-miR-143	CLIP-seq
MIRT1348936	hsa-miR-2115	CLIP-seq
MIRT2103392	hsa-miR-299-5p	CLIP-seq
MIRT2103393	hsa-miR-3117-5p	CLIP-seq
MIRT1348942	hsa-miR-3137	CLIP-seq
MIRT2103394	hsa-miR-3167	CLIP-seq
MIRT2103395	hsa-miR-3182	CLIP-seq
MIRT1348946	hsa-miR-3198	CLIP-seq
MIRT2103396	hsa-miR-3622a-3p	CLIP-seq
MIRT2103397	hsa-miR-3622b-3p	CLIP-seq
MIRT1348950	hsa-miR-3660	CLIP-seq
MIRT2103398	hsa-miR-3663-3p	CLIP-seq
MIRT2103399	hsa-miR-3686	CLIP-seq
MIRT2103400	hsa-miR-3690	CLIP-seq
MIRT2103401	hsa-miR-3691-3p	CLIP-seq
MIRT2103402	hsa-miR-4254	CLIP-seq
MIRT1348954	hsa-miR-4256	CLIP-seq
MIRT2103403	hsa-miR-4280	CLIP-seq
MIRT1348955	hsa-miR-4294	CLIP-seq
MIRT1348956	hsa-miR-4309	CLIP-seq
MIRT2103404	hsa-miR-4314	CLIP-seq
MIRT1348957	hsa-miR-4324	CLIP-seq
MIRT2103405	hsa-miR-4420	CLIP-seq
MIRT2103406	hsa-miR-4493	CLIP-seq
MIRT1348960	hsa-miR-4526	CLIP-seq
MIRT2103407	hsa-miR-4667-5p	CLIP-seq
MIRT2103408	hsa-miR-4683	CLIP-seq
MIRT2103409	hsa-miR-4686	CLIP-seq
MIRT2103410	hsa-miR-4700-5p	CLIP-seq
MIRT1348965	hsa-miR-4735-5p	CLIP-seq
MIRT2103411	hsa-miR-4760-3p	CLIP-seq
MIRT2103412	hsa-miR-4770	CLIP-seq
MIRT2103413	hsa-miR-4775	CLIP-seq
MIRT1348967	hsa-miR-4778-5p	CLIP-seq
MIRT2103414	hsa-miR-4793-5p	CLIP-seq
MIRT1348969	hsa-miR-496	CLIP-seq
MIRT2103415	hsa-miR-5096	CLIP-seq
MIRT2103416	hsa-miR-515-3p	CLIP-seq
MIRT2103417	hsa-miR-516a-3p	CLIP-seq
MIRT1348971	hsa-miR-516b	CLIP-seq
MIRT2103418	hsa-miR-519e	CLIP-seq
MIRT1348978	hsa-miR-544b	CLIP-seq
MIRT1348983	hsa-miR-582-5p	CLIP-seq
MIRT2103419	hsa-miR-590-3p	CLIP-seq
MIRT2103420	hsa-miR-606	CLIP-seq
MIRT2103421	hsa-miR-615-5p	CLIP-seq
MIRT2103422	hsa-miR-620	CLIP-seq
MIRT2103423	hsa-miR-634	CLIP-seq
MIRT2103424	hsa-miR-637	CLIP-seq
MIRT2103425	hsa-miR-664	CLIP-seq
MIRT2103426	hsa-miR-876-5p	CLIP-seq
MIRT1348925	hsa-miR-1200	CLIP-seq
MIRT2327652	hsa-miR-1236	CLIP-seq
MIRT2327653	hsa-miR-1237	CLIP-seq
MIRT2327654	hsa-miR-124	CLIP-seq
MIRT2327655	hsa-miR-1244	CLIP-seq
MIRT2103386	hsa-miR-1270	CLIP-seq
MIRT2327656	hsa-miR-1275	CLIP-seq
MIRT2103387	hsa-miR-128	CLIP-seq
MIRT1348927	hsa-miR-1289	CLIP-seq
MIRT2103391	hsa-miR-143	CLIP-seq
MIRT2327657	hsa-miR-1915	CLIP-seq
MIRT2327658	hsa-miR-205	CLIP-seq
MIRT1348936	hsa-miR-2115	CLIP-seq
MIRT2327659	hsa-miR-216b	CLIP-seq
MIRT2327660	hsa-miR-223	CLIP-seq
MIRT1348940	hsa-miR-2681	CLIP-seq
MIRT2103392	hsa-miR-299-5p	CLIP-seq
MIRT2327661	hsa-miR-3153	CLIP-seq
MIRT1348945	hsa-miR-3176	CLIP-seq
MIRT2327662	hsa-miR-3179	CLIP-seq
MIRT2327663	hsa-miR-3189-5p	CLIP-seq
MIRT1348946	hsa-miR-3198	CLIP-seq
MIRT2103396	hsa-miR-3622a-3p	CLIP-seq
MIRT2103397	hsa-miR-3622b-3p	CLIP-seq
MIRT2327664	hsa-miR-3650	CLIP-seq
MIRT2103398	hsa-miR-3663-3p	CLIP-seq
MIRT2327665	hsa-miR-3675-3p	CLIP-seq
MIRT2327666	hsa-miR-3688-3p	CLIP-seq
MIRT2103401	hsa-miR-3691-3p	CLIP-seq
MIRT1348951	hsa-miR-3922-3p	CLIP-seq
MIRT2327667	hsa-miR-3936	CLIP-seq
MIRT2327668	hsa-miR-3978	CLIP-seq
MIRT2327669	hsa-miR-4257	CLIP-seq
MIRT2327670	hsa-miR-4286	CLIP-seq
MIRT1348955	hsa-miR-4294	CLIP-seq
MIRT1348956	hsa-miR-4309	CLIP-seq
MIRT1348957	hsa-miR-4324	CLIP-seq
MIRT2327671	hsa-miR-4422	CLIP-seq
MIRT1348958	hsa-miR-4435	CLIP-seq
MIRT2327672	hsa-miR-4455	CLIP-seq
MIRT1348959	hsa-miR-4459	CLIP-seq
MIRT2327673	hsa-miR-4463	CLIP-seq
MIRT2103406	hsa-miR-4493	CLIP-seq
MIRT2327674	hsa-miR-4494	CLIP-seq
MIRT2327675	hsa-miR-4525	CLIP-seq
MIRT2327676	hsa-miR-4665-5p	CLIP-seq
MIRT2103407	hsa-miR-4667-5p	CLIP-seq
MIRT2327677	hsa-miR-4668-3p	CLIP-seq
MIRT2103408	hsa-miR-4683	CLIP-seq
MIRT2327678	hsa-miR-4685-5p	CLIP-seq
MIRT2327679	hsa-miR-4697-3p	CLIP-seq
MIRT2103410	hsa-miR-4700-5p	CLIP-seq
MIRT2327680	hsa-miR-4723-5p	CLIP-seq
MIRT1348964	hsa-miR-4729	CLIP-seq
MIRT2103412	hsa-miR-4770	CLIP-seq
MIRT1348967	hsa-miR-4778-5p	CLIP-seq
MIRT2103414	hsa-miR-4793-5p	CLIP-seq
MIRT2327681	hsa-miR-4797-5p	CLIP-seq
MIRT1348969	hsa-miR-496	CLIP-seq
MIRT2327682	hsa-miR-499a-5p	CLIP-seq
MIRT2327683	hsa-miR-506	CLIP-seq
MIRT2103416	hsa-miR-515-3p	CLIP-seq
MIRT2103417	hsa-miR-516a-3p	CLIP-seq
MIRT1348971	hsa-miR-516b	CLIP-seq
MIRT2103418	hsa-miR-519e	CLIP-seq
MIRT1348978	hsa-miR-544b	CLIP-seq
MIRT2327684	hsa-miR-548an	CLIP-seq
MIRT2327685	hsa-miR-592	CLIP-seq
MIRT2327686	hsa-miR-597	CLIP-seq
MIRT2103422	hsa-miR-620	CLIP-seq
MIRT2327687	hsa-miR-625	CLIP-seq
MIRT2103424	hsa-miR-637	CLIP-seq
MIRT2327688	hsa-miR-646	CLIP-seq
MIRT2103425	hsa-miR-664	CLIP-seq
MIRT1348986	hsa-miR-665	CLIP-seq
MIRT2327689	hsa-miR-875-3p	CLIP-seq
MIRT2327690	hsa-miR-944	CLIP-seq
MIRT2327653	hsa-miR-1237	CLIP-seq
MIRT2394539	hsa-miR-1273e	CLIP-seq
MIRT2103387	hsa-miR-128	CLIP-seq
MIRT2327657	hsa-miR-1915	CLIP-seq
MIRT1348935	hsa-miR-203	CLIP-seq
MIRT2103393	hsa-miR-3117-5p	CLIP-seq
MIRT2394540	hsa-miR-3591-5p	CLIP-seq
MIRT2103398	hsa-miR-3663-3p	CLIP-seq
MIRT2327666	hsa-miR-3688-3p	CLIP-seq
MIRT2103401	hsa-miR-3691-3p	CLIP-seq
MIRT2327678	hsa-miR-4685-5p	CLIP-seq
MIRT2103414	hsa-miR-4793-5p	CLIP-seq
MIRT2327681	hsa-miR-4797-5p	CLIP-seq
MIRT2103416	hsa-miR-515-3p	CLIP-seq
MIRT2103418	hsa-miR-519e	CLIP-seq
MIRT2394541	hsa-miR-544	CLIP-seq
MIRT2327686	hsa-miR-597	CLIP-seq
MIRT1348925	hsa-miR-1200	CLIP-seq
MIRT2440408	hsa-miR-1205	CLIP-seq
MIRT2327653	hsa-miR-1237	CLIP-seq
MIRT2440409	hsa-miR-1286	CLIP-seq
MIRT1348927	hsa-miR-1289	CLIP-seq
MIRT2327657	hsa-miR-1915	CLIP-seq
MIRT2440410	hsa-miR-214	CLIP-seq
MIRT2103393	hsa-miR-3117-5p	CLIP-seq
MIRT2327662	hsa-miR-3179	CLIP-seq
MIRT1348946	hsa-miR-3198	CLIP-seq
MIRT2440411	hsa-miR-3619-5p	CLIP-seq
MIRT2103402	hsa-miR-4254	CLIP-seq
MIRT2440412	hsa-miR-4291	CLIP-seq
MIRT1348955	hsa-miR-4294	CLIP-seq
MIRT2440413	hsa-miR-4308	CLIP-seq
MIRT1348956	hsa-miR-4309	CLIP-seq
MIRT1348957	hsa-miR-4324	CLIP-seq
MIRT2440414	hsa-miR-4418	CLIP-seq
MIRT2440415	hsa-miR-4421	CLIP-seq
MIRT2440416	hsa-miR-4519	CLIP-seq
MIRT2440417	hsa-miR-4530	CLIP-seq
MIRT2327678	hsa-miR-4685-5p	CLIP-seq
MIRT2440418	hsa-miR-4707-3p	CLIP-seq
MIRT2440419	hsa-miR-4722-5p	CLIP-seq
MIRT2440420	hsa-miR-4738-3p	CLIP-seq
MIRT1348969	hsa-miR-496	CLIP-seq
MIRT2440421	hsa-miR-509-3-5p	CLIP-seq
MIRT2440422	hsa-miR-509-5p	CLIP-seq
MIRT1348971	hsa-miR-516b	CLIP-seq
MIRT1348978	hsa-miR-544b	CLIP-seq
MIRT2327688	hsa-miR-646	CLIP-seq
MIRT2440423	hsa-miR-761	CLIP-seq
MIRT2440424	hsa-miR-922	CLIP-seq
MIRT1348925	hsa-miR-1200	CLIP-seq
MIRT2327653	hsa-miR-1237	CLIP-seq
MIRT2103386	hsa-miR-1270	CLIP-seq
MIRT2622710	hsa-miR-1273	CLIP-seq
MIRT2103387	hsa-miR-128	CLIP-seq
MIRT1348926	hsa-miR-1288	CLIP-seq
MIRT2103391	hsa-miR-143	CLIP-seq
MIRT2622711	hsa-miR-1914	CLIP-seq
MIRT2327657	hsa-miR-1915	CLIP-seq
MIRT1348936	hsa-miR-2115	CLIP-seq
MIRT2622712	hsa-miR-2682	CLIP-seq
MIRT2622713	hsa-miR-28-5p	CLIP-seq
MIRT2622714	hsa-miR-300	CLIP-seq
MIRT2622715	hsa-miR-3074-5p	CLIP-seq
MIRT2103393	hsa-miR-3117-5p	CLIP-seq
MIRT2622716	hsa-miR-3139	CLIP-seq
MIRT2622717	hsa-miR-3152-5p	CLIP-seq
MIRT1348945	hsa-miR-3176	CLIP-seq
MIRT2327662	hsa-miR-3179	CLIP-seq
MIRT1348947	hsa-miR-3199	CLIP-seq
MIRT2622718	hsa-miR-326	CLIP-seq
MIRT2622719	hsa-miR-330-3p	CLIP-seq
MIRT2622720	hsa-miR-330-5p	CLIP-seq
MIRT2622721	hsa-miR-339-3p	CLIP-seq
MIRT2103396	hsa-miR-3622a-3p	CLIP-seq
MIRT2103397	hsa-miR-3622b-3p	CLIP-seq
MIRT2327664	hsa-miR-3650	CLIP-seq
MIRT2103398	hsa-miR-3663-3p	CLIP-seq
MIRT2327666	hsa-miR-3688-3p	CLIP-seq
MIRT2103401	hsa-miR-3691-3p	CLIP-seq
MIRT2622722	hsa-miR-381	CLIP-seq
MIRT2622723	hsa-miR-3908	CLIP-seq
MIRT2622724	hsa-miR-3920	CLIP-seq
MIRT1348951	hsa-miR-3922-3p	CLIP-seq
MIRT2327667	hsa-miR-3936	CLIP-seq
MIRT2622725	hsa-miR-3942-5p	CLIP-seq
MIRT2103403	hsa-miR-4280	CLIP-seq
MIRT2622726	hsa-miR-4312	CLIP-seq
MIRT1348958	hsa-miR-4435	CLIP-seq
MIRT2327672	hsa-miR-4455	CLIP-seq
MIRT2622727	hsa-miR-4487	CLIP-seq
MIRT2103406	hsa-miR-4493	CLIP-seq
MIRT2622728	hsa-miR-449c	CLIP-seq
MIRT2622729	hsa-miR-4514	CLIP-seq
MIRT2622730	hsa-miR-4645-5p	CLIP-seq
MIRT2622731	hsa-miR-4661-5p	CLIP-seq
MIRT2622732	hsa-miR-4666-3p	CLIP-seq
MIRT2622733	hsa-miR-4673	CLIP-seq
MIRT2103408	hsa-miR-4683	CLIP-seq
MIRT2327678	hsa-miR-4685-5p	CLIP-seq
MIRT2622734	hsa-miR-4692	CLIP-seq
MIRT2622735	hsa-miR-4703-5p	CLIP-seq
MIRT2622736	hsa-miR-4710	CLIP-seq
MIRT2440420	hsa-miR-4738-3p	CLIP-seq
MIRT2622737	hsa-miR-4766-3p	CLIP-seq
MIRT2103412	hsa-miR-4770	CLIP-seq
MIRT2622738	hsa-miR-4774-3p	CLIP-seq
MIRT2622739	hsa-miR-4778-3p	CLIP-seq
MIRT2622740	hsa-miR-4792	CLIP-seq
MIRT2103414	hsa-miR-4793-5p	CLIP-seq
MIRT2327681	hsa-miR-4797-5p	CLIP-seq
MIRT2103416	hsa-miR-515-3p	CLIP-seq
MIRT2103417	hsa-miR-516a-3p	CLIP-seq
MIRT2103418	hsa-miR-519e	CLIP-seq
MIRT2622741	hsa-miR-520d-5p	CLIP-seq
MIRT2622742	hsa-miR-524-5p	CLIP-seq
MIRT2622743	hsa-miR-526b	CLIP-seq
MIRT2622744	hsa-miR-548g	CLIP-seq
MIRT2327685	hsa-miR-592	CLIP-seq
MIRT2622745	hsa-miR-593	CLIP-seq
MIRT2327686	hsa-miR-597	CLIP-seq
MIRT2103420	hsa-miR-606	CLIP-seq
MIRT2103422	hsa-miR-620	CLIP-seq
MIRT2622746	hsa-miR-708	CLIP-seq
MIRT1348988	hsa-miR-767-3p	CLIP-seq
MIRT1348925	hsa-miR-1200	CLIP-seq
MIRT2327653	hsa-miR-1237	CLIP-seq
MIRT2103386	hsa-miR-1270	CLIP-seq
MIRT2622710	hsa-miR-1273	CLIP-seq
MIRT2103387	hsa-miR-128	CLIP-seq
MIRT1348926	hsa-miR-1288	CLIP-seq
MIRT2103391	hsa-miR-143	CLIP-seq
MIRT2622711	hsa-miR-1914	CLIP-seq
MIRT2327657	hsa-miR-1915	CLIP-seq
MIRT1348936	hsa-miR-2115	CLIP-seq
MIRT2622712	hsa-miR-2682	CLIP-seq
MIRT2622713	hsa-miR-28-5p	CLIP-seq
MIRT2622714	hsa-miR-300	CLIP-seq
MIRT2622715	hsa-miR-3074-5p	CLIP-seq
MIRT2103393	hsa-miR-3117-5p	CLIP-seq
MIRT2622716	hsa-miR-3139	CLIP-seq
MIRT1348945	hsa-miR-3176	CLIP-seq
MIRT2327662	hsa-miR-3179	CLIP-seq
MIRT1348947	hsa-miR-3199	CLIP-seq
MIRT2622718	hsa-miR-326	CLIP-seq
MIRT2622719	hsa-miR-330-3p	CLIP-seq
MIRT2622720	hsa-miR-330-5p	CLIP-seq
MIRT2622721	hsa-miR-339-3p	CLIP-seq
MIRT2103396	hsa-miR-3622a-3p	CLIP-seq
MIRT2103397	hsa-miR-3622b-3p	CLIP-seq
MIRT2327664	hsa-miR-3650	CLIP-seq
MIRT2103398	hsa-miR-3663-3p	CLIP-seq
MIRT2327666	hsa-miR-3688-3p	CLIP-seq
MIRT2103401	hsa-miR-3691-3p	CLIP-seq
MIRT2690749	hsa-miR-378g	CLIP-seq
MIRT2622722	hsa-miR-381	CLIP-seq
MIRT2622724	hsa-miR-3920	CLIP-seq
MIRT1348951	hsa-miR-3922-3p	CLIP-seq
MIRT2327667	hsa-miR-3936	CLIP-seq
MIRT2690750	hsa-miR-4261	CLIP-seq
MIRT2103404	hsa-miR-4314	CLIP-seq
MIRT1348958	hsa-miR-4435	CLIP-seq
MIRT2690751	hsa-miR-4437	CLIP-seq
MIRT2327672	hsa-miR-4455	CLIP-seq
MIRT2622727	hsa-miR-4487	CLIP-seq
MIRT2103406	hsa-miR-4493	CLIP-seq
MIRT2622728	hsa-miR-449c	CLIP-seq
MIRT2622729	hsa-miR-4514	CLIP-seq
MIRT2622730	hsa-miR-4645-5p	CLIP-seq
MIRT2622732	hsa-miR-4666-3p	CLIP-seq
MIRT2103407	hsa-miR-4667-5p	CLIP-seq
MIRT2622733	hsa-miR-4673	CLIP-seq
MIRT2690752	hsa-miR-4674	CLIP-seq
MIRT2103408	hsa-miR-4683	CLIP-seq
MIRT2327678	hsa-miR-4685-5p	CLIP-seq
MIRT2622734	hsa-miR-4692	CLIP-seq
MIRT2690753	hsa-miR-4694-3p	CLIP-seq
MIRT2103410	hsa-miR-4700-5p	CLIP-seq
MIRT2622736	hsa-miR-4710	CLIP-seq
MIRT2440420	hsa-miR-4738-3p	CLIP-seq
MIRT2103412	hsa-miR-4770	CLIP-seq
MIRT2622740	hsa-miR-4792	CLIP-seq
MIRT2103414	hsa-miR-4793-5p	CLIP-seq
MIRT2327681	hsa-miR-4797-5p	CLIP-seq
MIRT2690754	hsa-miR-494	CLIP-seq
MIRT2103416	hsa-miR-515-3p	CLIP-seq
MIRT2103417	hsa-miR-516a-3p	CLIP-seq
MIRT2103418	hsa-miR-519e	CLIP-seq
MIRT2622741	hsa-miR-520d-5p	CLIP-seq
MIRT2690755	hsa-miR-522	CLIP-seq
MIRT2622742	hsa-miR-524-5p	CLIP-seq
MIRT2622744	hsa-miR-548g	CLIP-seq
MIRT2327685	hsa-miR-592	CLIP-seq
MIRT2622745	hsa-miR-593	CLIP-seq
MIRT2327686	hsa-miR-597	CLIP-seq
MIRT2103420	hsa-miR-606	CLIP-seq
MIRT2103421	hsa-miR-615-5p	CLIP-seq
MIRT2103422	hsa-miR-620	CLIP-seq
MIRT2103423	hsa-miR-634	CLIP-seq
MIRT2103424	hsa-miR-637	CLIP-seq
MIRT2622746	hsa-miR-708	CLIP-seq
MIRT1348988	hsa-miR-767-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000287	Function	Magnesium ion binding	IDA	14976552
GO:0000287	Function	Magnesium ion binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	14976552, 18348280, 26983400
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	16306228, 20708153, 25416956, 27478041, 32814053
GO:0005524	Function	ATP binding	IDA	14976552
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	24129571
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0006468	Process	Protein phosphorylation	IDA	14976552
GO:0008610	Process	Lipid biosynthetic process	IDA	21084751
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0035556	Process	Intracellular signal transduction	IDA	14976552
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0036503	Process	ERAD pathway	IDA	24129571
GO:0046626	Process	Regulation of insulin receptor signaling pathway	ISS
GO:0046777	Process	Protein autophosphorylation	IDA	18348280
GO:0046872	Function	Metal ion binding	IEA
GO:0106310	Function	Protein serine kinase activity	IDA	24129571
GO:0106310	Function	Protein serine kinase activity	IEA

Other IDs

• MIM: 608973
• HGNC: 21680
• e!Ensembl: ENSG00000170145

Protein

• UniProt ID: Q9H0K1
• Protein name: Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)
• Protein function: Serine/threonine-protein kinase that plays a role in many biological processes such as fatty acid oxidation, autophagy, immune response or glucose metabolism (PubMed:23322770, PubMed:26983400). Phosphorylates 'Ser-794' of IRS1 in insulin-stimula
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	20 → 271	Protein kinase domain	Domain

• Sequence:

  MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN
  LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR
  RKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSP
  PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM
  SEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQV
  LRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTI
  AEQTVAKAQTVGLPVTMHSPNMRLLRSALLPQASNVEAFSFPASGCQAEAAFMEEECVDT
  PKVNGCLLDPVPPVLVRKGCQSLPSNMMETSIDEGLETEGEAEEDPAHAFEAFQSTRSGQ
  RRHTLSEVTNQLVVMPGAGKIFSMNDSPSLDSVDSEYDMGSVQRDLNFLEDNPSLKDIML
  ANQPSPRMTSPFISLRPTNPAMQALSSQKREVHNRSPVSFREGRRASDTSLTQGIVAFRQ
  HLQNLARTKGILELNKVQLLYEQIGPEADPNLAPAAPQLQDLASSCPQEEVSQQQESVST
  LPASVHPQLSPRQSLETQYLQHRLQKPSLLSKAQNTCQLYCKEPPRSLEQQLQEHRLQQK
  RLFLQKQSQLQAYFNQMQIAESSYPQPSQQLPLPRQETPPPSQQAPPFSLTQPLSPVLEP
  SSEQMQYSPFLSQYQEMQLQPLPSTSGPRAAPPLPTQLQQQQPPPPPPPPPPRQPGAAPA
  PLQFSYQTCELPSAASPAPDYPTPCQYPVDGAQQSDLTGPDCPRSPGLQEAPSSYDPLAL
  SELPGLFDCEMLDAVDPQHNGYVLVN

• Sequence length: 926

Pathways

KEGG:

Glucagon signaling pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ASTHMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATOPIC ECZEMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, HEPATOCELLULAR	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RESPIRATORY SYSTEM DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCLEROSING CHOLANGITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adult Diffuse Large B-Cell Lymphoma	B-cell Lymphoma	BEFREE	20367563		★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	GWASCAT_DG	31619474		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Carcinoma	Breast Carcinoma	BEFREE	29774109		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinogenesis	Carcinogenesis	Pubtator	24980480	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	29774109		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	29191878		★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	20708153, 27478041, 30004169, 31639424		★☆☆☆☆ Found in Text Mining only
Cholangitis, Sclerosing	Cholangitis	GWASCAT_DG	23603763, 27992413		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	BEFREE	27236538		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	27236538, 34986532	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34558647	Stimulate	★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	30503507		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	21084751		★☆☆☆☆ Found in Text Mining only
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	BEFREE	20367563		★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	30004169		★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty Liver	BEFREE	21084751		★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	35642638	Associate	★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	37386070	Inhibit	★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	29191878, 29526696		★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	34986532	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	29774109		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	29191878		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	20708153, 27478041, 31639424		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	25548099		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	27678456, 30528240, 30723708		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	30503507		★☆☆☆☆ Found in Text Mining only
Metaphyseal chondrodysplasia	Metaphyseal Chondrodysplasia	BEFREE	31430259		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27697861, 29774109, 30723708		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	21084751		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	37386070	Inhibit	★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	20708153, 27478041, 31639424		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	20708153, 25548099, 32016960, 34737212, 35278271, 35642638	Associate	★☆☆☆☆ Found in Text Mining only
Primary sclerosing cholangitis	Sclerosing Cholangitis	GWASDB_DG	23603763		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	25548099		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	25548099	Associate	★☆☆☆☆ Found in Text Mining only
Steatohepatitis	Fatty Liver	BEFREE	21084751		★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple Negative Breast Neoplasms	BEFREE	27697861, 29774109		★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	35642638	Associate	★☆☆☆☆ Found in Text Mining only
Uveal melanoma	Uveal melanoma	Pubtator	37966164	Associate	★☆☆☆☆ Found in Text Mining only