Gene Gene information from NCBI Gene database.
Entrez ID 23234
Gene name DnaJ heat shock protein family (Hsp40) member C9
Gene symbol DNAJC9
Synonyms (NCBI Gene)
HDJC9JDD1SB73
Chromosome 10
Chromosome location 10q22.2
miRNA miRNA information provided by mirtarbase database.
319
miRTarBase ID miRNA Experiments Reference
MIRT016456 hsa-miR-193b-3p Microarray 20304954
MIRT021665 hsa-miR-140-3p Sequencing 20371350
MIRT027178 hsa-miR-103a-3p Sequencing 20371350
MIRT031865 hsa-miR-16-5p Sequencing 20371350
MIRT031865 hsa-miR-16-5p Proteomics 18668040
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 19410544, 25281560, 29568061, 32296183, 33857403
GO:0005615 Component Extracellular space IDA 17182002
GO:0005634 Component Nucleus HDA 21630459
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IDA 17182002
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611206 19123 ENSG00000213551
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WXX5
Protein name DnaJ homolog subfamily C member 9 (HDJC9) (DnaJ protein SB73)
Protein function Acts as a dual histone chaperone and heat shock co-chaperone (PubMed:33857403). As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers; and may thereby assist MCM2 in histone H3-H4 heterodimer recognition a
PDB 7CIZ , 7CJ0
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00226 DnaJ 15 79 DnaJ domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, thymus, ovary, colon and peripheral blood. {ECO:0000269|PubMed:17182002}.
Sequence
MGLLDLCEEVFGTADLYRVLGVRREASDGEVRRGYHKVSLQVHPDRVGEGDKEDATRRFQ
ILGKVYSVLSDREQRAVYD
EQGTVDEDSPVLTQDRDWEAYWRLLFKKISLEDIQAFEKTY
KGSEEELADIKQAYLDFKGDMDQIMESVLCVQYTEEPRIRNIIQQAIDAGEVPSYNAFVK
ESKQKMNARKRRAQEEAKEAEMSRKELGLDEGVDSLKAAIQSRQKDRQKEMDNFLAQMEA
KYCKSSKGGGKKSALKKEKK
Sequence length 260
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
JOUBERT SYNDROME 36 Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Epithelial Recurrent Erosion Dystrophy Epithelial Erosion Dystrophy BEFREE 26786512
★☆☆☆☆
Found in Text Mining only
Lung Neoplasms Lung neoplasms Pubtator 33225964 Associate
★☆☆☆☆
Found in Text Mining only