Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23217
Gene name	Zinc finger RNA binding protein 2
Gene symbol	ZFR2
Synonyms (NCBI Gene)	KIAA1086
Chromosome	19
Chromosome location	19p13.3

Show/Hide all (86)

miRTarBase ID	miRNA	Experiments	Reference
MIRT519081	hsa-miR-1911-3p	PAR-CLIP	23446348
MIRT519080	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT519079	hsa-miR-197-3p	PAR-CLIP	23446348
MIRT461148	hsa-miR-6886-5p	PAR-CLIP	23592263
MIRT461147	hsa-miR-3665	PAR-CLIP	23592263
MIRT519081	hsa-miR-1911-3p	PAR-CLIP	23446348
MIRT519080	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT519079	hsa-miR-197-3p	PAR-CLIP	23446348
MIRT461148	hsa-miR-6886-5p	PAR-CLIP	23592263
MIRT461147	hsa-miR-3665	PAR-CLIP	23592263
MIRT1512018	hsa-miR-1207-3p	CLIP-seq
MIRT1512019	hsa-miR-2861	CLIP-seq
MIRT1512020	hsa-miR-3165	CLIP-seq
MIRT1512021	hsa-miR-3650	CLIP-seq
MIRT1512022	hsa-miR-3689d	CLIP-seq
MIRT1512023	hsa-miR-4456	CLIP-seq
MIRT1512024	hsa-miR-4501	CLIP-seq
MIRT1512025	hsa-miR-4504	CLIP-seq
MIRT1512026	hsa-miR-541	CLIP-seq
MIRT1512027	hsa-miR-542-3p	CLIP-seq
MIRT1512028	hsa-miR-654-5p	CLIP-seq
MIRT1512029	hsa-let-7a	CLIP-seq
MIRT1512030	hsa-let-7b	CLIP-seq
MIRT1512031	hsa-let-7c	CLIP-seq
MIRT1512032	hsa-let-7d	CLIP-seq
MIRT1512033	hsa-let-7e	CLIP-seq
MIRT1512034	hsa-let-7f	CLIP-seq
MIRT1512035	hsa-let-7g	CLIP-seq
MIRT1512036	hsa-let-7i	CLIP-seq
MIRT1512037	hsa-miR-106a	CLIP-seq
MIRT1512038	hsa-miR-106b	CLIP-seq
MIRT1512039	hsa-miR-1182	CLIP-seq
MIRT1512040	hsa-miR-1234	CLIP-seq
MIRT1512041	hsa-miR-1273d	CLIP-seq
MIRT1512042	hsa-miR-1275	CLIP-seq
MIRT1512043	hsa-miR-17	CLIP-seq
MIRT1512044	hsa-miR-20a	CLIP-seq
MIRT1512045	hsa-miR-20b	CLIP-seq
MIRT1512046	hsa-miR-302a	CLIP-seq
MIRT1512047	hsa-miR-302b	CLIP-seq
MIRT1512048	hsa-miR-302c	CLIP-seq
MIRT1512049	hsa-miR-302d	CLIP-seq
MIRT1512050	hsa-miR-302e	CLIP-seq
MIRT1512051	hsa-miR-3607-3p	CLIP-seq
MIRT1512052	hsa-miR-3686	CLIP-seq
MIRT1512053	hsa-miR-371-5p	CLIP-seq
MIRT1512054	hsa-miR-371b-5p	CLIP-seq
MIRT1512055	hsa-miR-372	CLIP-seq
MIRT1512056	hsa-miR-373	CLIP-seq
MIRT1512057	hsa-miR-3973	CLIP-seq
MIRT1512058	hsa-miR-4438	CLIP-seq
MIRT1512059	hsa-miR-4447	CLIP-seq
MIRT1512060	hsa-miR-4458	CLIP-seq
MIRT1512061	hsa-miR-4472	CLIP-seq
MIRT1512062	hsa-miR-4500	CLIP-seq
MIRT1512063	hsa-miR-4525	CLIP-seq
MIRT1512064	hsa-miR-4665-5p	CLIP-seq
MIRT1512065	hsa-miR-4723-5p	CLIP-seq
MIRT1512066	hsa-miR-4731-5p	CLIP-seq
MIRT1512067	hsa-miR-4757-5p	CLIP-seq
MIRT1512068	hsa-miR-5095	CLIP-seq
MIRT1512069	hsa-miR-512-3p	CLIP-seq
MIRT1512070	hsa-miR-519d	CLIP-seq
MIRT1512071	hsa-miR-520a-3p	CLIP-seq
MIRT1512072	hsa-miR-520b	CLIP-seq
MIRT1512073	hsa-miR-520c-3p	CLIP-seq
MIRT1512074	hsa-miR-520d-3p	CLIP-seq
MIRT1512075	hsa-miR-520e	CLIP-seq
MIRT1512076	hsa-miR-520g	CLIP-seq
MIRT1512077	hsa-miR-520h	CLIP-seq
MIRT1512078	hsa-miR-625	CLIP-seq
MIRT1512079	hsa-miR-720	CLIP-seq
MIRT1512080	hsa-miR-93	CLIP-seq
MIRT1512081	hsa-miR-98	CLIP-seq
MIRT1512041	hsa-miR-1273d	CLIP-seq
MIRT2154149	hsa-miR-3199	CLIP-seq
MIRT2154150	hsa-miR-3672	CLIP-seq
MIRT2374395	hsa-miR-1271	CLIP-seq
MIRT2374396	hsa-miR-142-5p	CLIP-seq
MIRT2374397	hsa-miR-561	CLIP-seq
MIRT2374398	hsa-miR-96	CLIP-seq
MIRT2154149	hsa-miR-3199	CLIP-seq
MIRT2463959	hsa-miR-4755-3p	CLIP-seq
MIRT2463960	hsa-miR-552	CLIP-seq
MIRT2463961	hsa-miR-591	CLIP-seq
MIRT2463962	hsa-miR-764	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003725	Function	Double-stranded RNA binding	IBA
GO:0003727	Function	Single-stranded RNA binding	IBA
GO:0008270	Function	Zinc ion binding	IEA

MIM	HGNC	e!Ensembl
619284	29189	ENSG00000105278

Q9UPR6

Protein name

Zinc finger RNA-binding protein 2

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12874	zf-met	271 → 295		Domain
PF12874	zf-met	319 → 343		Domain
PF12874	zf-met	468 → 492		Domain
PF07528	DZF	658 → 904	DZF domain	Domain

Sequence

MATSQYFDFAQGGGPQYSAQPPTLPLPTVGASYTAQPTPGMDPAVNPAFPPAAPAGYGGY
QPHSGQDFAYGSRPQEPVPTATTMATYQDSYSYGQSAAARSYEDRPYFQSAALQSGRMTA
ADSGQPGTQEACGQPSPHGSHSHAQPPQQAPIVESGQPASTLSSGYTYPTATGVQPESSA
SIVTSYPPPSYNPTCTAYTAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQLPPPPAPA
GSGSSPRADSKPPLPSKLPRPKAGPRQLQLHYCDICKISCAGPQTYREHLGGQKHRKKEA
AQKTGVQPNGSPRGVQAQLHCDLCAVSCTGADAYAAHIRGSKHQKVFKLHAKLGKPIPTL
EPALATESPPGAEAKPTSPTGPSVCASSRPALAKRPVASKALCEGPPEPQAAGCRPQWGK
PAQPKLEGPGAPTQGGSKEAPAGCSDAQPVGPEYVEEVFSDEGRVLRFHCKLCECSFNDL
NAKDLHVRGRRHRLQYRKKVNPDLPIATEPSSRARKVLEERMRKQRHLAEERLEQLRRWH
AERRRLEEEPPQDVPPHAPPDWAQPLLMGRPESPASAPLQPGRRPASSDDRHVMCKHATI
YPTEQELLAVQRAVSHAERALKLVSDTLAEEDRGRREEEGDKRSSVAPQTRVLKGVMRVG
ILAKGLLLRGDRNVRLALLCSEKPTHSLLRRIAQQLPRQLQMVTEDEYEVSSDPEANIVI
SSCEEPRMQVTISVTSPLMREDPSTDPGVEEPQADAGDVLSPKKCLESLAALRHARWFQA
RASGLQPCVIVIRVLRDLCRRVPTWGALPAWAMELLVEKAVSSAAGPLGPGDAVRRVLEC
VATGTLLTDGPGLQDPCERDQTDALEPMTLQEREDVTASAQHALRMLAFRQTHKVLGMDL
LPPRHRLGARFRKRQRGPGEGEEGAGEKKRGRRGGEGLV

Sequence length

939

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Obesity	Obesity	CTD_human_DG	29273807		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	26902887	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZFR2 (zinc finger RNA binding protein 2)