SNX13 (sorting nexin 13)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23161 |
| Gene name | Sorting nexin 13 |
| Gene symbol | SNX13 |
| Synonyms (NCBI Gene) |
RGS-PX1
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| Chromosome | 7 |
| Chromosome location | 7p21.1 |
| Summary | This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are i |
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miRNA
miRNA information provided by mirtarbase database.
430
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y5W8 | |||||||||||||||||||||||||
| Protein name | Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) | |||||||||||||||||||||||||
| Protein function | May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity). Acts as a GAP for Galphas. | |||||||||||||||||||||||||
| PDB | 7WF6 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 968 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
9
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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