WDR43 (WD repeat domain 43)

Gene

• Entrez ID: 23160
• Gene name: WD repeat domain 43
• Gene symbol: WDR43
• Synonyms (NCBI Gene): NET12, UTP5
• Chromosome: 2
• Chromosome location: 2p23.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT031487	hsa-miR-16-5p	Proteomics	18668040
MIRT046118	hsa-miR-30b-5p	CLASH	23622248
MIRT037019	hsa-miR-877-3p	CLASH	23622248
MIRT1490569	hsa-miR-1185	CLIP-seq
MIRT1490570	hsa-miR-1207-3p	CLIP-seq
MIRT1490571	hsa-miR-1257	CLIP-seq
MIRT1490572	hsa-miR-128	CLIP-seq
MIRT1490573	hsa-miR-1285	CLIP-seq
MIRT1490574	hsa-miR-1290	CLIP-seq
MIRT1490575	hsa-miR-135a	CLIP-seq
MIRT1490576	hsa-miR-135b	CLIP-seq
MIRT1490577	hsa-miR-136	CLIP-seq
MIRT1490578	hsa-miR-149	CLIP-seq
MIRT1490579	hsa-miR-1827	CLIP-seq
MIRT1490580	hsa-miR-197	CLIP-seq
MIRT1490581	hsa-miR-2110	CLIP-seq
MIRT1490582	hsa-miR-223	CLIP-seq
MIRT1490583	hsa-miR-27a	CLIP-seq
MIRT1490584	hsa-miR-27b	CLIP-seq
MIRT1490585	hsa-miR-2964a-5p	CLIP-seq
MIRT1490586	hsa-miR-298	CLIP-seq
MIRT1490587	hsa-miR-3064-5p	CLIP-seq
MIRT1490588	hsa-miR-3119	CLIP-seq
MIRT1490589	hsa-miR-3120-3p	CLIP-seq
MIRT1490590	hsa-miR-3140-3p	CLIP-seq
MIRT1490591	hsa-miR-3143	CLIP-seq
MIRT1490592	hsa-miR-3145-5p	CLIP-seq
MIRT1490593	hsa-miR-3160-3p	CLIP-seq
MIRT1490594	hsa-miR-3160-5p	CLIP-seq
MIRT1490595	hsa-miR-3163	CLIP-seq
MIRT1490596	hsa-miR-3167	CLIP-seq
MIRT1490597	hsa-miR-3187-5p	CLIP-seq
MIRT1490598	hsa-miR-3189-3p	CLIP-seq
MIRT1490599	hsa-miR-340	CLIP-seq
MIRT1490600	hsa-miR-342-5p	CLIP-seq
MIRT1490601	hsa-miR-3605-5p	CLIP-seq
MIRT1490602	hsa-miR-3622b-5p	CLIP-seq
MIRT1490603	hsa-miR-3663-3p	CLIP-seq
MIRT1490604	hsa-miR-3664-3p	CLIP-seq
MIRT1490605	hsa-miR-3665	CLIP-seq
MIRT1490606	hsa-miR-3674	CLIP-seq
MIRT1490607	hsa-miR-3678-3p	CLIP-seq
MIRT1490608	hsa-miR-3679-5p	CLIP-seq
MIRT1490609	hsa-miR-3907	CLIP-seq
MIRT1490610	hsa-miR-3941	CLIP-seq
MIRT1490611	hsa-miR-410	CLIP-seq
MIRT1490612	hsa-miR-412	CLIP-seq
MIRT1490613	hsa-miR-4271	CLIP-seq
MIRT1490614	hsa-miR-4314	CLIP-seq
MIRT1490615	hsa-miR-4324	CLIP-seq
MIRT1490616	hsa-miR-4426	CLIP-seq
MIRT1490617	hsa-miR-4436a	CLIP-seq
MIRT1490618	hsa-miR-4477a	CLIP-seq
MIRT1490619	hsa-miR-450b-3p	CLIP-seq
MIRT1490620	hsa-miR-450b-5p	CLIP-seq
MIRT1490621	hsa-miR-4520a-3p	CLIP-seq
MIRT1490622	hsa-miR-4520b-3p	CLIP-seq
MIRT1490623	hsa-miR-4530	CLIP-seq
MIRT1490624	hsa-miR-4642	CLIP-seq
MIRT1490625	hsa-miR-4647	CLIP-seq
MIRT1490626	hsa-miR-4651	CLIP-seq
MIRT1490627	hsa-miR-4659a-5p	CLIP-seq
MIRT1490628	hsa-miR-4659b-5p	CLIP-seq
MIRT1490629	hsa-miR-466	CLIP-seq
MIRT1490630	hsa-miR-4662b	CLIP-seq
MIRT1490631	hsa-miR-4664-5p	CLIP-seq
MIRT1490632	hsa-miR-4667-5p	CLIP-seq
MIRT1490633	hsa-miR-4672	CLIP-seq
MIRT1490634	hsa-miR-4680-3p	CLIP-seq
MIRT1490635	hsa-miR-4687-5p	CLIP-seq
MIRT1490636	hsa-miR-4697-3p	CLIP-seq
MIRT1490637	hsa-miR-4699-3p	CLIP-seq
MIRT1490638	hsa-miR-4700-5p	CLIP-seq
MIRT1490639	hsa-miR-4711-3p	CLIP-seq
MIRT1490640	hsa-miR-4713-3p	CLIP-seq
MIRT1490641	hsa-miR-4725-3p	CLIP-seq
MIRT1490642	hsa-miR-4729	CLIP-seq
MIRT1490643	hsa-miR-4776-3p	CLIP-seq
MIRT1490644	hsa-miR-4778-3p	CLIP-seq
MIRT1490645	hsa-miR-4778-5p	CLIP-seq
MIRT1490646	hsa-miR-4782-5p	CLIP-seq
MIRT1490647	hsa-miR-4793-5p	CLIP-seq
MIRT1490648	hsa-miR-4794	CLIP-seq
MIRT1490649	hsa-miR-4796-3p	CLIP-seq
MIRT1490650	hsa-miR-4796-5p	CLIP-seq
MIRT1490651	hsa-miR-494	CLIP-seq
MIRT1490652	hsa-miR-518a-5p	CLIP-seq
MIRT1490653	hsa-miR-520g	CLIP-seq
MIRT1490654	hsa-miR-520h	CLIP-seq
MIRT1490655	hsa-miR-527	CLIP-seq
MIRT1490656	hsa-miR-543	CLIP-seq
MIRT1490657	hsa-miR-545	CLIP-seq
MIRT1490658	hsa-miR-548c-3p	CLIP-seq
MIRT1490659	hsa-miR-548n	CLIP-seq
MIRT1490660	hsa-miR-548t	CLIP-seq
MIRT1490661	hsa-miR-608	CLIP-seq
MIRT1490662	hsa-miR-612	CLIP-seq
MIRT1490663	hsa-miR-617	CLIP-seq
MIRT1490664	hsa-miR-633	CLIP-seq
MIRT1490665	hsa-miR-637	CLIP-seq
MIRT1490666	hsa-miR-638	CLIP-seq
MIRT1490667	hsa-miR-646	CLIP-seq
MIRT1490668	hsa-miR-656	CLIP-seq
MIRT1490669	hsa-miR-657	CLIP-seq
MIRT1490670	hsa-miR-760	CLIP-seq
MIRT1490671	hsa-miR-769-3p	CLIP-seq
MIRT1490672	hsa-miR-876-5p	CLIP-seq
MIRT1490573	hsa-miR-1285	CLIP-seq
MIRT1490575	hsa-miR-135a	CLIP-seq
MIRT1490576	hsa-miR-135b	CLIP-seq
MIRT2147906	hsa-miR-145	CLIP-seq
MIRT1490579	hsa-miR-1827	CLIP-seq
MIRT1490580	hsa-miR-197	CLIP-seq
MIRT1490591	hsa-miR-3143	CLIP-seq
MIRT1490592	hsa-miR-3145-5p	CLIP-seq
MIRT1490597	hsa-miR-3187-5p	CLIP-seq
MIRT1490606	hsa-miR-3674	CLIP-seq
MIRT2147907	hsa-miR-3925-3p	CLIP-seq
MIRT1490611	hsa-miR-410	CLIP-seq
MIRT1490624	hsa-miR-4642	CLIP-seq
MIRT2147908	hsa-miR-4686	CLIP-seq
MIRT1490635	hsa-miR-4687-5p	CLIP-seq
MIRT2147909	hsa-miR-4703-3p	CLIP-seq
MIRT1490647	hsa-miR-4793-5p	CLIP-seq
MIRT2147910	hsa-miR-508-5p	CLIP-seq
MIRT1490656	hsa-miR-543	CLIP-seq
MIRT1490662	hsa-miR-612	CLIP-seq
MIRT1490572	hsa-miR-128	CLIP-seq
MIRT2368326	hsa-miR-1284	CLIP-seq
MIRT2368327	hsa-miR-129-3p	CLIP-seq
MIRT1490575	hsa-miR-135a	CLIP-seq
MIRT1490576	hsa-miR-135b	CLIP-seq
MIRT1490577	hsa-miR-136	CLIP-seq
MIRT1490578	hsa-miR-149	CLIP-seq
MIRT2368328	hsa-miR-1913	CLIP-seq
MIRT1490581	hsa-miR-2110	CLIP-seq
MIRT2368329	hsa-miR-2115	CLIP-seq
MIRT2368330	hsa-miR-216b	CLIP-seq
MIRT1490583	hsa-miR-27a	CLIP-seq
MIRT1490584	hsa-miR-27b	CLIP-seq
MIRT1490587	hsa-miR-3064-5p	CLIP-seq
MIRT1490589	hsa-miR-3120-3p	CLIP-seq
MIRT2368331	hsa-miR-3130-3p	CLIP-seq
MIRT1490592	hsa-miR-3145-5p	CLIP-seq
MIRT2368332	hsa-miR-324-3p	CLIP-seq
MIRT1490600	hsa-miR-342-5p	CLIP-seq
MIRT2368333	hsa-miR-345	CLIP-seq
MIRT1490602	hsa-miR-3622b-5p	CLIP-seq
MIRT1490603	hsa-miR-3663-3p	CLIP-seq
MIRT1490604	hsa-miR-3664-3p	CLIP-seq
MIRT1490605	hsa-miR-3665	CLIP-seq
MIRT2368334	hsa-miR-3682-3p	CLIP-seq
MIRT1490609	hsa-miR-3907	CLIP-seq
MIRT1490610	hsa-miR-3941	CLIP-seq
MIRT1490613	hsa-miR-4271	CLIP-seq
MIRT1490614	hsa-miR-4314	CLIP-seq
MIRT2368335	hsa-miR-4325	CLIP-seq
MIRT1490616	hsa-miR-4426	CLIP-seq
MIRT1490617	hsa-miR-4436a	CLIP-seq
MIRT2368336	hsa-miR-4502	CLIP-seq
MIRT1490619	hsa-miR-450b-3p	CLIP-seq
MIRT1490625	hsa-miR-4647	CLIP-seq
MIRT1490626	hsa-miR-4651	CLIP-seq
MIRT1490627	hsa-miR-4659a-5p	CLIP-seq
MIRT1490628	hsa-miR-4659b-5p	CLIP-seq
MIRT1490629	hsa-miR-466	CLIP-seq
MIRT1490630	hsa-miR-4662b	CLIP-seq
MIRT1490631	hsa-miR-4664-5p	CLIP-seq
MIRT1490632	hsa-miR-4667-5p	CLIP-seq
MIRT1490633	hsa-miR-4672	CLIP-seq
MIRT1490637	hsa-miR-4699-3p	CLIP-seq
MIRT1490638	hsa-miR-4700-5p	CLIP-seq
MIRT1490640	hsa-miR-4713-3p	CLIP-seq
MIRT2368337	hsa-miR-4716-5p	CLIP-seq
MIRT2368338	hsa-miR-4719	CLIP-seq
MIRT1490641	hsa-miR-4725-3p	CLIP-seq
MIRT1490642	hsa-miR-4729	CLIP-seq
MIRT2368339	hsa-miR-4762-5p	CLIP-seq
MIRT1490643	hsa-miR-4776-3p	CLIP-seq
MIRT1490645	hsa-miR-4778-5p	CLIP-seq
MIRT2368340	hsa-miR-4789-5p	CLIP-seq
MIRT2368341	hsa-miR-4792	CLIP-seq
MIRT2368342	hsa-miR-4793-3p	CLIP-seq
MIRT1490648	hsa-miR-4794	CLIP-seq
MIRT1490649	hsa-miR-4796-3p	CLIP-seq
MIRT1490653	hsa-miR-520g	CLIP-seq
MIRT1490654	hsa-miR-520h	CLIP-seq
MIRT2368343	hsa-miR-526b	CLIP-seq
MIRT1490657	hsa-miR-545	CLIP-seq
MIRT2368344	hsa-miR-576-5p	CLIP-seq
MIRT1490661	hsa-miR-608	CLIP-seq
MIRT2368345	hsa-miR-616	CLIP-seq
MIRT1490664	hsa-miR-633	CLIP-seq
MIRT1490665	hsa-miR-637	CLIP-seq
MIRT1490666	hsa-miR-638	CLIP-seq
MIRT1490668	hsa-miR-656	CLIP-seq
MIRT1490669	hsa-miR-657	CLIP-seq
MIRT1490670	hsa-miR-760	CLIP-seq
MIRT1490671	hsa-miR-769-3p	CLIP-seq
MIRT2368346	hsa-miR-877	CLIP-seq
MIRT1490572	hsa-miR-128	CLIP-seq
MIRT1490573	hsa-miR-1285	CLIP-seq
MIRT1490579	hsa-miR-1827	CLIP-seq
MIRT1490580	hsa-miR-197	CLIP-seq
MIRT1490583	hsa-miR-27a	CLIP-seq
MIRT1490584	hsa-miR-27b	CLIP-seq
MIRT1490597	hsa-miR-3187-5p	CLIP-seq
MIRT1490635	hsa-miR-4687-5p	CLIP-seq
MIRT2441666	hsa-miR-4761-5p	CLIP-seq
MIRT2368341	hsa-miR-4792	CLIP-seq
MIRT1490662	hsa-miR-612	CLIP-seq
MIRT1490664	hsa-miR-633	CLIP-seq
MIRT1490569	hsa-miR-1185	CLIP-seq
MIRT1490571	hsa-miR-1257	CLIP-seq
MIRT2661944	hsa-miR-1279	CLIP-seq
MIRT1490572	hsa-miR-128	CLIP-seq
MIRT1490573	hsa-miR-1285	CLIP-seq
MIRT1490574	hsa-miR-1290	CLIP-seq
MIRT2661945	hsa-miR-141	CLIP-seq
MIRT2147906	hsa-miR-145	CLIP-seq
MIRT1490579	hsa-miR-1827	CLIP-seq
MIRT2661946	hsa-miR-188-5p	CLIP-seq
MIRT1490580	hsa-miR-197	CLIP-seq
MIRT2661947	hsa-miR-200a	CLIP-seq
MIRT2661948	hsa-miR-205	CLIP-seq
MIRT1490583	hsa-miR-27a	CLIP-seq
MIRT1490584	hsa-miR-27b	CLIP-seq
MIRT2661949	hsa-miR-30a	CLIP-seq
MIRT2661950	hsa-miR-30b	CLIP-seq
MIRT2661951	hsa-miR-30c	CLIP-seq
MIRT2661952	hsa-miR-30d	CLIP-seq
MIRT2661953	hsa-miR-30e	CLIP-seq
MIRT1490589	hsa-miR-3120-3p	CLIP-seq
MIRT1490592	hsa-miR-3145-5p	CLIP-seq
MIRT1490597	hsa-miR-3187-5p	CLIP-seq
MIRT1490598	hsa-miR-3189-3p	CLIP-seq
MIRT1490600	hsa-miR-342-5p	CLIP-seq
MIRT1490601	hsa-miR-3605-5p	CLIP-seq
MIRT1490602	hsa-miR-3622b-5p	CLIP-seq
MIRT2661954	hsa-miR-3647-3p	CLIP-seq
MIRT1490604	hsa-miR-3664-3p	CLIP-seq
MIRT2661955	hsa-miR-3672	CLIP-seq
MIRT1490606	hsa-miR-3674	CLIP-seq
MIRT1490608	hsa-miR-3679-5p	CLIP-seq
MIRT1490609	hsa-miR-3907	CLIP-seq
MIRT2147907	hsa-miR-3925-3p	CLIP-seq
MIRT1490610	hsa-miR-3941	CLIP-seq
MIRT2661956	hsa-miR-3944-5p	CLIP-seq
MIRT2661957	hsa-miR-3978	CLIP-seq
MIRT1490617	hsa-miR-4436a	CLIP-seq
MIRT2661958	hsa-miR-4480	CLIP-seq
MIRT1490619	hsa-miR-450b-3p	CLIP-seq
MIRT1490624	hsa-miR-4642	CLIP-seq
MIRT1490626	hsa-miR-4651	CLIP-seq
MIRT1490629	hsa-miR-466	CLIP-seq
MIRT1490631	hsa-miR-4664-5p	CLIP-seq
MIRT1490632	hsa-miR-4667-5p	CLIP-seq
MIRT1490633	hsa-miR-4672	CLIP-seq
MIRT1490635	hsa-miR-4687-5p	CLIP-seq
MIRT1490637	hsa-miR-4699-3p	CLIP-seq
MIRT1490638	hsa-miR-4700-5p	CLIP-seq
MIRT2147909	hsa-miR-4703-3p	CLIP-seq
MIRT1490640	hsa-miR-4713-3p	CLIP-seq
MIRT2441666	hsa-miR-4761-5p	CLIP-seq
MIRT2368341	hsa-miR-4792	CLIP-seq
MIRT1490647	hsa-miR-4793-5p	CLIP-seq
MIRT1490649	hsa-miR-4796-3p	CLIP-seq
MIRT1490651	hsa-miR-494	CLIP-seq
MIRT2147910	hsa-miR-508-5p	CLIP-seq
MIRT1490653	hsa-miR-520g	CLIP-seq
MIRT1490654	hsa-miR-520h	CLIP-seq
MIRT1490657	hsa-miR-545	CLIP-seq
MIRT2661959	hsa-miR-548ag	CLIP-seq
MIRT2661960	hsa-miR-548ai	CLIP-seq
MIRT2661961	hsa-miR-548m	CLIP-seq
MIRT1490661	hsa-miR-608	CLIP-seq
MIRT1490662	hsa-miR-612	CLIP-seq
MIRT1490664	hsa-miR-633	CLIP-seq
MIRT1490665	hsa-miR-637	CLIP-seq
MIRT1490666	hsa-miR-638	CLIP-seq
MIRT1490671	hsa-miR-769-3p	CLIP-seq
MIRT1490569	hsa-miR-1185	CLIP-seq
MIRT1490571	hsa-miR-1257	CLIP-seq
MIRT2661944	hsa-miR-1279	CLIP-seq
MIRT1490572	hsa-miR-128	CLIP-seq
MIRT1490573	hsa-miR-1285	CLIP-seq
MIRT1490574	hsa-miR-1290	CLIP-seq
MIRT2661945	hsa-miR-141	CLIP-seq
MIRT2147906	hsa-miR-145	CLIP-seq
MIRT1490579	hsa-miR-1827	CLIP-seq
MIRT2661946	hsa-miR-188-5p	CLIP-seq
MIRT1490580	hsa-miR-197	CLIP-seq
MIRT2661947	hsa-miR-200a	CLIP-seq
MIRT2661948	hsa-miR-205	CLIP-seq
MIRT1490583	hsa-miR-27a	CLIP-seq
MIRT1490584	hsa-miR-27b	CLIP-seq
MIRT2661949	hsa-miR-30a	CLIP-seq
MIRT2661950	hsa-miR-30b	CLIP-seq
MIRT2661951	hsa-miR-30c	CLIP-seq
MIRT2661952	hsa-miR-30d	CLIP-seq
MIRT2661953	hsa-miR-30e	CLIP-seq
MIRT1490589	hsa-miR-3120-3p	CLIP-seq
MIRT1490592	hsa-miR-3145-5p	CLIP-seq
MIRT1490597	hsa-miR-3187-5p	CLIP-seq
MIRT1490598	hsa-miR-3189-3p	CLIP-seq
MIRT1490600	hsa-miR-342-5p	CLIP-seq
MIRT1490601	hsa-miR-3605-5p	CLIP-seq
MIRT1490602	hsa-miR-3622b-5p	CLIP-seq
MIRT2661954	hsa-miR-3647-3p	CLIP-seq
MIRT1490604	hsa-miR-3664-3p	CLIP-seq
MIRT2661955	hsa-miR-3672	CLIP-seq
MIRT1490606	hsa-miR-3674	CLIP-seq
MIRT1490608	hsa-miR-3679-5p	CLIP-seq
MIRT1490609	hsa-miR-3907	CLIP-seq
MIRT2147907	hsa-miR-3925-3p	CLIP-seq
MIRT1490610	hsa-miR-3941	CLIP-seq
MIRT2661956	hsa-miR-3944-5p	CLIP-seq
MIRT2661957	hsa-miR-3978	CLIP-seq
MIRT1490617	hsa-miR-4436a	CLIP-seq
MIRT2661958	hsa-miR-4480	CLIP-seq
MIRT1490619	hsa-miR-450b-3p	CLIP-seq
MIRT1490624	hsa-miR-4642	CLIP-seq
MIRT1490626	hsa-miR-4651	CLIP-seq
MIRT1490629	hsa-miR-466	CLIP-seq
MIRT1490631	hsa-miR-4664-5p	CLIP-seq
MIRT1490632	hsa-miR-4667-5p	CLIP-seq
MIRT1490633	hsa-miR-4672	CLIP-seq
MIRT1490635	hsa-miR-4687-5p	CLIP-seq
MIRT1490637	hsa-miR-4699-3p	CLIP-seq
MIRT1490638	hsa-miR-4700-5p	CLIP-seq
MIRT2147909	hsa-miR-4703-3p	CLIP-seq
MIRT1490640	hsa-miR-4713-3p	CLIP-seq
MIRT2441666	hsa-miR-4761-5p	CLIP-seq
MIRT2368341	hsa-miR-4792	CLIP-seq
MIRT1490647	hsa-miR-4793-5p	CLIP-seq
MIRT1490649	hsa-miR-4796-3p	CLIP-seq
MIRT1490651	hsa-miR-494	CLIP-seq
MIRT2147910	hsa-miR-508-5p	CLIP-seq
MIRT1490653	hsa-miR-520g	CLIP-seq
MIRT1490654	hsa-miR-520h	CLIP-seq
MIRT1490657	hsa-miR-545	CLIP-seq
MIRT2661959	hsa-miR-548ag	CLIP-seq
MIRT2661960	hsa-miR-548ai	CLIP-seq
MIRT2661961	hsa-miR-548m	CLIP-seq
MIRT1490661	hsa-miR-608	CLIP-seq
MIRT1490662	hsa-miR-612	CLIP-seq
MIRT1490664	hsa-miR-633	CLIP-seq
MIRT1490665	hsa-miR-637	CLIP-seq
MIRT1490666	hsa-miR-638	CLIP-seq
MIRT1490671	hsa-miR-769-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000462	Process	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA
GO:0000785	Component	Chromatin	IEA
GO:0000785	Component	Chromatin	ISS
GO:0000993	Function	RNA polymerase II complex binding	IEA
GO:0000993	Function	RNA polymerase II complex binding	ISS
GO:0001650	Component	Fibrillar center	IDA	24219289
GO:0001650	Component	Fibrillar center	IEA
GO:0003711	Function	Transcription elongation factor activity	IEA
GO:0003711	Function	Transcription elongation factor activity	ISS
GO:0003723	Function	RNA binding	HDA	22658674
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	22916032, 24219289, 28514442, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	ISS
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA	17699751, 24219289
GO:0005730	Component	Nucleolus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006364	Process	RRNA processing	IEA
GO:0032040	Component	Small-subunit processome	IDA	34516797
GO:0034243	Process	Regulation of transcription elongation by RNA polymerase II	IEA
GO:0034243	Process	Regulation of transcription elongation by RNA polymerase II	ISS
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042274	Process	Ribosomal small subunit biogenesis	IDA	34516797
GO:0045943	Process	Positive regulation of transcription by RNA polymerase I	IMP	17699751
GO:2000036	Process	Regulation of stem cell population maintenance	IEA
GO:2000036	Process	Regulation of stem cell population maintenance	ISS
GO:2000234	Process	Positive regulation of rRNA processing	IMP	17699751

Other IDs

• MIM: 616195
• HGNC: 28945
• e!Ensembl: ENSG00000163811

Protein

• UniProt ID: Q15061
• Protein name: WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog)
• Protein function: Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis (PubMed:17699751). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU proces
• PDB: 7MQ8, 7MQ9, 7MQA
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00400	WD40	115 → 154	WD domain, G-beta repeat	Repeat
  PF00400	WD40	157 → 194	WD domain, G-beta repeat	Repeat
  PF04003	Utp12	473 → 577	Dip2/Utp12 Family	Family

• Sequence:

  MAAGGGGSCDPLAPAGVPCAFSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSG
  TCTCLAWAPARLQAKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKL
  ISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDG
  KMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGA
  VHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFE
  HILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAGFCSDKMSLLLVYGSWFQPTIE
  RVALNSREPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAIKPAPP
  QTEQVESKRKSGGNEVSIEERLGAMDIDTHKKGKEDLQTNSFPVLLTQGLESNDFEMLNK
  VLQTRNVNLIKKTVLRMPLHTIIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLST
  LPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYE
  EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK
  ELNGDSDLDPENESEEE

• Sequence length: 677

Pathways

KEGG:

Ribosome biogenesis in eukaryotes

Reactome:

Major pathway of rRNA processing in the nucleolus and cytosol

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESTROGEN-RECEPTOR NEGATIVE BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Uncertain significance; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial pancreatic carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUMINAL A BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TRIPLE-NEGATIVE BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Carcinoma	Breast Carcinoma	GWASCAT_DG	27117709		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	27117709, 34803163	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	29658574	Associate	★☆☆☆☆ Found in Text Mining only
Mandibulofacial Dysostosis	Mandibulofacial Dysostosis	BEFREE	24497835		★☆☆☆☆ Found in Text Mining only
Pulmonary Arterial Hypertension	Pulmonary arterial hypertension	Pubtator	38110868	Associate	★☆☆☆☆ Found in Text Mining only
Sepsis	Sepsis	Pubtator	39438952	Associate	★☆☆☆☆ Found in Text Mining only