Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	23133
Gene name	PHD finger protein 8
Gene symbol	PHF8
Synonyms (NCBI Gene)	JHDM1FKDM7BMRXSSDZNF422
Chromosome	X
Chromosome location	Xp11.22
Summary	The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an

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SNP ID	Visualize variation	Clinical significance	Consequence
rs121918522	G>A	Pathogenic	Coding sequence variant, stop gained
rs121918523	T>A	Pathogenic	Coding sequence variant, stop gained
rs121918524	A>G	Pathogenic	Coding sequence variant, missense variant
rs797044665	G>C	Likely-pathogenic	Stop gained, coding sequence variant
rs878853148	C>G	Pathogenic	Intron variant
rs1057518729	A>-	Pathogenic	Frameshift variant, coding sequence variant
rs1557099144	->C	Pathogenic	Frameshift variant, coding sequence variant
rs1557110385	->T	Pathogenic	Frameshift variant, coding sequence variant
rs1603298803	G>A	Pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs1603305030	T>C	Likely-pathogenic	Splice acceptor variant
rs1603314287	->T	Pathogenic	Coding sequence variant, frameshift variant
rs1603338257	->A	Pathogenic	Coding sequence variant, frameshift variant
rs1603339671	->T	Pathogenic	Coding sequence variant, frameshift variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019133	hsa-miR-335-5p	Microarray	18185580
MIRT050476	hsa-miR-20a-5p	CLASH	23622248
MIRT041284	hsa-miR-193b-3p	CLASH	23622248
MIRT037650	hsa-miR-744-5p	CLASH	23622248
MIRT036321	hsa-miR-1229-3p	CLASH	23622248
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT521936	hsa-miR-300	HITS-CLIP	21572407
MIRT521935	hsa-miR-381-3p	HITS-CLIP	21572407
MIRT521934	hsa-miR-4666a-3p	HITS-CLIP	21572407
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521932	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT521931	hsa-miR-331-5p	HITS-CLIP	21572407
MIRT521930	hsa-let-7a-3p	HITS-CLIP	21572407
MIRT521929	hsa-let-7b-3p	HITS-CLIP	21572407
MIRT521928	hsa-let-7f-1-3p	HITS-CLIP	21572407
MIRT521927	hsa-miR-98-3p	HITS-CLIP	21572407
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT521924	hsa-miR-6509-5p	HITS-CLIP	21572407
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521932	hsa-miR-656-3p	HITS-CLIP	23313552
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521932	hsa-miR-656-3p	HITS-CLIP	23313552
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	23706177
MIRT521932	hsa-miR-656-3p	HITS-CLIP	23706177
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	23706177
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	23706177
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT544654	hsa-miR-514a-5p	PAR-CLIP	20371350
MIRT544653	hsa-miR-1272	PAR-CLIP	20371350
MIRT544652	hsa-miR-326	PAR-CLIP	20371350
MIRT544651	hsa-miR-330-5p	PAR-CLIP	20371350
MIRT544650	hsa-miR-4667-5p	PAR-CLIP	20371350
MIRT544648	hsa-miR-4700-5p	PAR-CLIP	20371350
MIRT544649	hsa-miR-8089	PAR-CLIP	20371350
MIRT544647	hsa-miR-637	PAR-CLIP	20371350
MIRT544646	hsa-miR-7155-5p	PAR-CLIP	20371350
MIRT544645	hsa-miR-4680-5p	PAR-CLIP	20371350
MIRT544643	hsa-miR-3175	PAR-CLIP	20371350
MIRT544642	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT544641	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT544640	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT544639	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT544638	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT521932	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT521932	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT521931	hsa-miR-331-5p	PAR-CLIP	20371350
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT521924	hsa-miR-6509-5p	PAR-CLIP	20371350
MIRT544654	hsa-miR-514a-5p	PAR-CLIP	21572407
MIRT544653	hsa-miR-1272	PAR-CLIP	21572407
MIRT544652	hsa-miR-326	PAR-CLIP	21572407
MIRT544651	hsa-miR-330-5p	PAR-CLIP	21572407
MIRT544650	hsa-miR-4667-5p	PAR-CLIP	21572407
MIRT544648	hsa-miR-4700-5p	PAR-CLIP	21572407
MIRT544649	hsa-miR-8089	PAR-CLIP	21572407
MIRT544647	hsa-miR-637	PAR-CLIP	21572407
MIRT544646	hsa-miR-7155-5p	PAR-CLIP	21572407
MIRT544645	hsa-miR-4680-5p	PAR-CLIP	21572407
MIRT544644	hsa-miR-5187-5p	PAR-CLIP	21572407
MIRT544643	hsa-miR-3175	PAR-CLIP	21572407
MIRT544642	hsa-miR-1343-5p	PAR-CLIP	21572407
MIRT544641	hsa-miR-939-5p	PAR-CLIP	21572407
MIRT544640	hsa-miR-6825-5p	PAR-CLIP	21572407
MIRT544639	hsa-miR-3150a-3p	PAR-CLIP	21572407
MIRT544638	hsa-miR-6763-5p	PAR-CLIP	21572407
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT521936	hsa-miR-300	PAR-CLIP	23446348
MIRT521935	hsa-miR-381-3p	PAR-CLIP	23446348
MIRT521934	hsa-miR-4666a-3p	PAR-CLIP	23446348
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521932	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT521931	hsa-miR-331-5p	PAR-CLIP	23446348
MIRT521930	hsa-let-7a-3p	PAR-CLIP	23446348
MIRT521929	hsa-let-7b-3p	PAR-CLIP	23446348
MIRT521928	hsa-let-7f-1-3p	PAR-CLIP	23446348
MIRT521927	hsa-miR-98-3p	PAR-CLIP	23446348
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521925	hsa-miR-5007-3p	PAR-CLIP	23446348
MIRT521924	hsa-miR-6509-5p	PAR-CLIP	23446348
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	27292025
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	27292025
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	27292025
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	27292025
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	27292025
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	27292025
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	27292025
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	27292025
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	27292025
MIRT521932	hsa-miR-656-3p	PAR-CLIP	27292025
MIRT521932	hsa-miR-656-3p	PAR-CLIP	27292025
MIRT521932	hsa-miR-656-3p	PAR-CLIP	27292025
MIRT732854	hsa-miR-22-3p	Luciferase reporter assayqRT-PCRWestern blotting	33111613
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT710557	hsa-miR-936	HITS-CLIP	19536157
MIRT710556	hsa-miR-199a-3p	HITS-CLIP	19536157
MIRT710555	hsa-miR-199b-3p	HITS-CLIP	19536157
MIRT710554	hsa-miR-3129-5p	HITS-CLIP	19536157
MIRT710553	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT710552	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT710551	hsa-miR-222-5p	HITS-CLIP	19536157
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT521936	hsa-miR-300	HITS-CLIP	21572407
MIRT521935	hsa-miR-381-3p	HITS-CLIP	21572407
MIRT521934	hsa-miR-4666a-3p	HITS-CLIP	21572407
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT521932	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT521931	hsa-miR-331-5p	HITS-CLIP	21572407
MIRT521930	hsa-let-7a-3p	HITS-CLIP	21572407
MIRT521929	hsa-let-7b-3p	HITS-CLIP	21572407
MIRT521928	hsa-let-7f-1-3p	HITS-CLIP	21572407
MIRT521927	hsa-miR-98-3p	HITS-CLIP	21572407
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT521924	hsa-miR-6509-5p	HITS-CLIP	21572407
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521932	hsa-miR-656-3p	HITS-CLIP	23313552
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT521932	hsa-miR-656-3p	HITS-CLIP	23313552
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT521933	hsa-miR-5011-5p	HITS-CLIP	23706177
MIRT521932	hsa-miR-656-3p	HITS-CLIP	23706177
MIRT521926	hsa-miR-190a-3p	HITS-CLIP	23706177
MIRT521937	hsa-miR-1277-5p	HITS-CLIP	23706177
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT616232	hsa-miR-603	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT614161	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT611093	hsa-miR-649	HITS-CLIP	23824327
MIRT611092	hsa-miR-8485	HITS-CLIP	23824327
MIRT611091	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611090	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611089	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611088	hsa-miR-1284	HITS-CLIP	23824327
MIRT611087	hsa-miR-3941	HITS-CLIP	23824327
MIRT611086	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT544654	hsa-miR-514a-5p	PAR-CLIP	20371350
MIRT544653	hsa-miR-1272	PAR-CLIP	20371350
MIRT544652	hsa-miR-326	PAR-CLIP	20371350
MIRT544651	hsa-miR-330-5p	PAR-CLIP	20371350
MIRT544650	hsa-miR-4667-5p	PAR-CLIP	20371350
MIRT544648	hsa-miR-4700-5p	PAR-CLIP	20371350
MIRT544649	hsa-miR-8089	PAR-CLIP	20371350
MIRT544647	hsa-miR-637	PAR-CLIP	20371350
MIRT544646	hsa-miR-7155-5p	PAR-CLIP	20371350
MIRT544645	hsa-miR-4680-5p	PAR-CLIP	20371350
MIRT544643	hsa-miR-3175	PAR-CLIP	20371350
MIRT544642	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT544641	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT544640	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT544639	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT544638	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT521932	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT521932	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT521931	hsa-miR-331-5p	PAR-CLIP	20371350
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT521924	hsa-miR-6509-5p	PAR-CLIP	20371350
MIRT544654	hsa-miR-514a-5p	PAR-CLIP	21572407
MIRT544653	hsa-miR-1272	PAR-CLIP	21572407
MIRT544652	hsa-miR-326	PAR-CLIP	21572407
MIRT544651	hsa-miR-330-5p	PAR-CLIP	21572407
MIRT544650	hsa-miR-4667-5p	PAR-CLIP	21572407
MIRT544648	hsa-miR-4700-5p	PAR-CLIP	21572407
MIRT544649	hsa-miR-8089	PAR-CLIP	21572407
MIRT544647	hsa-miR-637	PAR-CLIP	21572407
MIRT544646	hsa-miR-7155-5p	PAR-CLIP	21572407
MIRT544645	hsa-miR-4680-5p	PAR-CLIP	21572407
MIRT544644	hsa-miR-5187-5p	PAR-CLIP	21572407
MIRT544643	hsa-miR-3175	PAR-CLIP	21572407
MIRT544642	hsa-miR-1343-5p	PAR-CLIP	21572407
MIRT544641	hsa-miR-939-5p	PAR-CLIP	21572407
MIRT544640	hsa-miR-6825-5p	PAR-CLIP	21572407
MIRT544639	hsa-miR-3150a-3p	PAR-CLIP	21572407
MIRT544638	hsa-miR-6763-5p	PAR-CLIP	21572407
MIRT521937	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT521936	hsa-miR-300	PAR-CLIP	23446348
MIRT521935	hsa-miR-381-3p	PAR-CLIP	23446348
MIRT521934	hsa-miR-4666a-3p	PAR-CLIP	23446348
MIRT521933	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT521932	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT521931	hsa-miR-331-5p	PAR-CLIP	23446348
MIRT521930	hsa-let-7a-3p	PAR-CLIP	23446348
MIRT521929	hsa-let-7b-3p	PAR-CLIP	23446348
MIRT521928	hsa-let-7f-1-3p	PAR-CLIP	23446348
MIRT521927	hsa-miR-98-3p	PAR-CLIP	23446348
MIRT521926	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT521925	hsa-miR-5007-3p	PAR-CLIP	23446348
MIRT521924	hsa-miR-6509-5p	PAR-CLIP	23446348
MIRT1231243	hsa-miR-3154	CLIP-seq
MIRT1231244	hsa-miR-4785	CLIP-seq
MIRT1231245	hsa-miR-615-5p	CLIP-seq
MIRT1231246	hsa-let-7a	CLIP-seq
MIRT1231247	hsa-let-7b	CLIP-seq
MIRT1231248	hsa-let-7c	CLIP-seq
MIRT1231249	hsa-let-7d	CLIP-seq
MIRT1231250	hsa-let-7e	CLIP-seq
MIRT1231251	hsa-let-7f	CLIP-seq
MIRT1231252	hsa-let-7g	CLIP-seq
MIRT1231253	hsa-let-7i	CLIP-seq
MIRT1231254	hsa-miR-129-5p	CLIP-seq
MIRT1231255	hsa-miR-134	CLIP-seq
MIRT1231256	hsa-miR-146a	CLIP-seq
MIRT1231257	hsa-miR-146b-5p	CLIP-seq
MIRT1231258	hsa-miR-2682	CLIP-seq
MIRT1231259	hsa-miR-28-3p	CLIP-seq
MIRT1231260	hsa-miR-3065-5p	CLIP-seq
MIRT1231261	hsa-miR-3118	CLIP-seq
MIRT1231262	hsa-miR-3119	CLIP-seq
MIRT1231263	hsa-miR-3120-3p	CLIP-seq
MIRT1231264	hsa-miR-3123	CLIP-seq
MIRT1231265	hsa-miR-3140-3p	CLIP-seq
MIRT1231266	hsa-miR-3152-5p	CLIP-seq
MIRT1231267	hsa-miR-3164	CLIP-seq
MIRT1231268	hsa-miR-3188	CLIP-seq
MIRT1231269	hsa-miR-328	CLIP-seq
MIRT1231270	hsa-miR-331-3p	CLIP-seq
MIRT1231271	hsa-miR-3650	CLIP-seq
MIRT1231272	hsa-miR-3914	CLIP-seq
MIRT1231273	hsa-miR-3921	CLIP-seq
MIRT1231274	hsa-miR-3925-5p	CLIP-seq
MIRT1231275	hsa-miR-3927	CLIP-seq
MIRT1231276	hsa-miR-3978	CLIP-seq
MIRT1231277	hsa-miR-409-5p	CLIP-seq
MIRT1231278	hsa-miR-4261	CLIP-seq
MIRT1231279	hsa-miR-4269	CLIP-seq
MIRT1231280	hsa-miR-4274	CLIP-seq
MIRT1231281	hsa-miR-4278	CLIP-seq
MIRT1231282	hsa-miR-4292	CLIP-seq
MIRT1231283	hsa-miR-4423-5p	CLIP-seq
MIRT1231284	hsa-miR-4434	CLIP-seq
MIRT1231285	hsa-miR-4436a	CLIP-seq
MIRT1231286	hsa-miR-4451	CLIP-seq
MIRT1231287	hsa-miR-4458	CLIP-seq
MIRT1231288	hsa-miR-449c	CLIP-seq
MIRT1231289	hsa-miR-4500	CLIP-seq
MIRT1231290	hsa-miR-4509	CLIP-seq
MIRT1231291	hsa-miR-4514	CLIP-seq
MIRT1231292	hsa-miR-4516	CLIP-seq
MIRT1231293	hsa-miR-4531	CLIP-seq
MIRT1231294	hsa-miR-4534	CLIP-seq
MIRT1231295	hsa-miR-4649-3p	CLIP-seq
MIRT1231296	hsa-miR-4653-5p	CLIP-seq
MIRT1231297	hsa-miR-4676-5p	CLIP-seq
MIRT1231298	hsa-miR-4692	CLIP-seq
MIRT1231299	hsa-miR-4700-3p	CLIP-seq
MIRT1231300	hsa-miR-4704-3p	CLIP-seq
MIRT1231301	hsa-miR-4714-5p	CLIP-seq
MIRT1231302	hsa-miR-4716-3p	CLIP-seq
MIRT1231303	hsa-miR-4723-5p	CLIP-seq
MIRT1231304	hsa-miR-4742-5p	CLIP-seq
MIRT1231305	hsa-miR-4755-3p	CLIP-seq
MIRT1231306	hsa-miR-4774-3p	CLIP-seq
MIRT1231307	hsa-miR-495	CLIP-seq
MIRT1231308	hsa-miR-575	CLIP-seq
MIRT1231245	hsa-miR-615-5p	CLIP-seq
MIRT1231309	hsa-miR-618	CLIP-seq
MIRT1231310	hsa-miR-9	CLIP-seq
MIRT1231311	hsa-miR-98	CLIP-seq
MIRT1231312	hsa-miR-1185	CLIP-seq
MIRT1231313	hsa-miR-135a	CLIP-seq
MIRT1231314	hsa-miR-135b	CLIP-seq
MIRT1231315	hsa-miR-148a	CLIP-seq
MIRT1231316	hsa-miR-148b	CLIP-seq
MIRT1231317	hsa-miR-152	CLIP-seq
MIRT1231318	hsa-miR-219-1-3p	CLIP-seq
MIRT1231319	hsa-miR-25	CLIP-seq
MIRT1231320	hsa-miR-3121-3p	CLIP-seq
MIRT1231321	hsa-miR-3125	CLIP-seq
MIRT1231322	hsa-miR-3163	CLIP-seq
MIRT1231323	hsa-miR-3184	CLIP-seq
MIRT1231324	hsa-miR-32	CLIP-seq
MIRT1231325	hsa-miR-3201	CLIP-seq
MIRT1231326	hsa-miR-3202	CLIP-seq
MIRT1231327	hsa-miR-3616-5p	CLIP-seq
MIRT1231328	hsa-miR-363	CLIP-seq
MIRT1231329	hsa-miR-3647-5p	CLIP-seq
MIRT1231330	hsa-miR-3652	CLIP-seq
MIRT1231331	hsa-miR-367	CLIP-seq
MIRT1231332	hsa-miR-3679-5p	CLIP-seq
MIRT1231333	hsa-miR-3916	CLIP-seq
MIRT1231334	hsa-miR-423-5p	CLIP-seq
MIRT1231335	hsa-miR-4430	CLIP-seq
MIRT1231336	hsa-miR-4492	CLIP-seq
MIRT1231337	hsa-miR-4498	CLIP-seq
MIRT1231338	hsa-miR-4517	CLIP-seq
MIRT1231339	hsa-miR-4533	CLIP-seq
MIRT1231340	hsa-miR-4670-3p	CLIP-seq
MIRT1231341	hsa-miR-4687-3p	CLIP-seq
MIRT1231342	hsa-miR-4729	CLIP-seq
MIRT1231343	hsa-miR-4791	CLIP-seq
MIRT1231344	hsa-miR-496	CLIP-seq
MIRT1231345	hsa-miR-548a-5p	CLIP-seq
MIRT1231346	hsa-miR-548ab	CLIP-seq
MIRT1231347	hsa-miR-548ak	CLIP-seq
MIRT1231348	hsa-miR-548b-5p	CLIP-seq
MIRT1231349	hsa-miR-548c-5p	CLIP-seq
MIRT1231350	hsa-miR-548d-5p	CLIP-seq
MIRT1231351	hsa-miR-548h	CLIP-seq
MIRT1231352	hsa-miR-548i	CLIP-seq
MIRT1231353	hsa-miR-548j	CLIP-seq
MIRT1231354	hsa-miR-548w	CLIP-seq
MIRT1231355	hsa-miR-548y	CLIP-seq
MIRT1231356	hsa-miR-559	CLIP-seq
MIRT1231357	hsa-miR-568	CLIP-seq
MIRT1231358	hsa-miR-571	CLIP-seq
MIRT1231359	hsa-miR-573	CLIP-seq
MIRT1231360	hsa-miR-762	CLIP-seq
MIRT1231361	hsa-miR-877	CLIP-seq
MIRT1231362	hsa-miR-92a	CLIP-seq
MIRT1231363	hsa-miR-92b	CLIP-seq
MIRT2067889	hsa-miR-1296	CLIP-seq
MIRT2067890	hsa-miR-3689d	CLIP-seq
MIRT1231282	hsa-miR-4292	CLIP-seq
MIRT2067891	hsa-miR-4512	CLIP-seq
MIRT2067892	hsa-miR-4520a-5p	CLIP-seq
MIRT2067893	hsa-miR-4520b-5p	CLIP-seq
MIRT2067894	hsa-miR-4640-5p	CLIP-seq
MIRT2067895	hsa-miR-4645-5p	CLIP-seq
MIRT2067896	hsa-miR-4668-3p	CLIP-seq
MIRT2067897	hsa-miR-4673	CLIP-seq
MIRT1231297	hsa-miR-4676-5p	CLIP-seq
MIRT2067898	hsa-miR-4686	CLIP-seq
MIRT2067899	hsa-miR-4698	CLIP-seq
MIRT2067900	hsa-miR-4726-5p	CLIP-seq
MIRT1231304	hsa-miR-4742-5p	CLIP-seq
MIRT1231305	hsa-miR-4755-3p	CLIP-seq
MIRT1231307	hsa-miR-495	CLIP-seq
MIRT2067901	hsa-miR-548m	CLIP-seq
MIRT1231308	hsa-miR-575	CLIP-seq
MIRT2067902	hsa-miR-605	CLIP-seq
MIRT2067903	hsa-miR-607	CLIP-seq
MIRT2067904	hsa-miR-616	CLIP-seq
MIRT2295328	hsa-miR-1273f	CLIP-seq
MIRT1231260	hsa-miR-3065-5p	CLIP-seq
MIRT1231243	hsa-miR-3154	CLIP-seq
MIRT2295329	hsa-miR-3160-5p	CLIP-seq
MIRT2295330	hsa-miR-3192	CLIP-seq
MIRT2295331	hsa-miR-320e	CLIP-seq
MIRT2295332	hsa-miR-3692	CLIP-seq
MIRT2295333	hsa-miR-3918	CLIP-seq
MIRT1231276	hsa-miR-3978	CLIP-seq
MIRT2295334	hsa-miR-4314	CLIP-seq
MIRT2295335	hsa-miR-4417	CLIP-seq
MIRT2295336	hsa-miR-4476	CLIP-seq
MIRT1231339	hsa-miR-4533	CLIP-seq
MIRT2295337	hsa-miR-4536	CLIP-seq
MIRT2067895	hsa-miR-4645-5p	CLIP-seq
MIRT2295338	hsa-miR-4646-5p	CLIP-seq
MIRT2295339	hsa-miR-4661-3p	CLIP-seq
MIRT2067897	hsa-miR-4673	CLIP-seq
MIRT2295340	hsa-miR-4685-5p	CLIP-seq
MIRT2295341	hsa-miR-4690-5p	CLIP-seq
MIRT2295342	hsa-miR-4722-3p	CLIP-seq
MIRT2295343	hsa-miR-4728-5p	CLIP-seq
MIRT2295344	hsa-miR-4731-5p	CLIP-seq
MIRT1231305	hsa-miR-4755-3p	CLIP-seq
MIRT2295345	hsa-miR-486-3p	CLIP-seq
MIRT2295346	hsa-miR-488	CLIP-seq
MIRT1231307	hsa-miR-495	CLIP-seq
MIRT2295347	hsa-miR-541	CLIP-seq
MIRT2295348	hsa-miR-654-5p	CLIP-seq
MIRT1231310	hsa-miR-9	CLIP-seq
MIRT2592961	hsa-miR-141	CLIP-seq
MIRT2592962	hsa-miR-150	CLIP-seq
MIRT2592963	hsa-miR-200a	CLIP-seq
MIRT2592964	hsa-miR-3680	CLIP-seq
MIRT2592965	hsa-miR-494	CLIP-seq
MIRT2592961	hsa-miR-141	CLIP-seq
MIRT2592962	hsa-miR-150	CLIP-seq
MIRT2592963	hsa-miR-200a	CLIP-seq
MIRT2592964	hsa-miR-3680	CLIP-seq
MIRT2592965	hsa-miR-494	CLIP-seq

Show/Hide all (42)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000082	Process	G1/S transition of mitotic cell cycle	IMP	20622854
GO:0003682	Function	Chromatin binding	IDA	20622854
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0005506	Function	Iron ion binding	IDA	20023638
GO:0005506	Function	Iron ion binding	IEA
GO:0005515	Function	Protein binding	IPI	20208542, 20346720, 20622854, 23022380, 23518351, 32051553, 34356104
GO:0005634	Component	Nucleus	IC	20023638
GO:0005634	Component	Nucleus	IDA	19843542, 31691806
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	20208542
GO:0005730	Component	Nucleolus	IEA
GO:0006325	Process	Chromatin organization	IEA
GO:0006338	Process	Chromatin remodeling	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007420	Process	Brain development	ISS
GO:0008270	Function	Zinc ion binding	IDA	20023638
GO:0008270	Function	Zinc ion binding	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0031965	Component	Nuclear membrane	IDA
GO:0032452	Function	Histone demethylase activity	IBA
GO:0032452	Function	Histone demethylase activity	IDA	19843542
GO:0032452	Function	Histone demethylase activity	TAS
GO:0032454	Function	Histone H3K9 demethylase activity	IDA	20208542, 20346720, 20622853, 20622854
GO:0032454	Function	Histone H3K9 demethylase activity	IEA
GO:0035575	Function	Histone H4K20 demethylase activity	IDA	20622853
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	20622853
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IMP	20346720, 20622854
GO:0045943	Process	Positive regulation of transcription by RNA polymerase I	IDA	20208542
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	31691806
GO:0046872	Function	Metal ion binding	IEA
GO:0051213	Function	Dioxygenase activity	IEA
GO:0051864	Function	Histone H3K36 demethylase activity	IDA	20208542, 20622853
GO:0061188	Process	Negative regulation of rDNA heterochromatin formation	IDA	20208542
GO:0061188	Process	Negative regulation of rDNA heterochromatin formation	IEA
GO:0071558	Function	Histone H3K27me2/H3K27me3 demethylase activity	IDA	20622853, 20622854
GO:0140002	Function	Histone H3K4me3 reader activity	IDA	20208542, 20346720, 20622854, 21029866
GO:0140680	Function	Histone H3K36me/H3K36me2 demethylase activity	IEA
GO:0140683	Function	Histone H3K9me/H3K9me2 demethylase activity	IDA	20023638
GO:0140683	Function	Histone H3K9me/H3K9me2 demethylase activity	IEA

MIM	HGNC	e!Ensembl
300560	20672	ENSG00000172943

Q9UPP1

Protein name

Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8)

Protein function

Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K

PDB

2WWU , 3K3N , 3K3O , 3KV4 , 4DO0 , 7CMZ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00628	PHD	43 → 92	PHD-finger	Domain
PF02373	JmjC	270 → 370	JmjC domain, hydroxylase	Domain
PF17811	JHD	374 → 477	Jumonji helical domain	Domain

Sequence

MNRSRAIVQRGRVLPPPAPLDTTNLAGRRTLQGRAKMASVPVYCLCRLPYDVTRFMIECD
MCQDWFHGSCVGVEEEKAADIDLYHCPNCEVLHGPSIMKKRRGSSKGHDTHKGKPVKTGS
PTFVRELRSRTFDSSDEVILKPTGNQLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTV
RDVEHYVGSDKEIDVIDVTRQADCKMKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLV
ETPKIVRKLSWVENLWPEECVFERPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEK
IFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVDKCYKCSVKQGQTLFIPTGWIHAVLTP
VDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFRFPNFETICWYVGKHILDIFRGLRE
NRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDEIPETVRTVQLIKDLAREIRLVEDIF
QQNVGKTSNIFGLQRIFPAGSIPLTRPAHSTSVSMSRLSLPSKNGSKKKGLKPKELFKKA
ERKGKESSALGPAGQLSYNLMDTYSHQALKTGSFQKAKFNITGACLNDSDDDSPDLDLDG
NESPLALLMSNGSTKRVKSLSKSRRTKIAKKVDKARLMAEQVMEDEFDLDSDDELQIDER
LGKEKATLIIRPKFPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEGKLGN
GSGAGGILDLLKASRQVGGPDYAALTEAPASPSTQEAIQGMLCMANLQSSSSSPATSSLQ
AWWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENASLDEQDS
LGACFKDAEYIYPSLESDDDDPALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGT
RVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDSNLSLTVPAPTVAA
TPQLVTSSSPLPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRP
SVGSQSNQAGQGKRPKKGLATAKQRLGRILKIHRNGKLLL

Sequence length

1060

Interactions

View interactions

	Reactome
			Condensation of Prophase Chromosomes HDMs demethylate histones

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Intellectual disability	Pathogenic	rs878853148	RCV000224454	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
PHF8-related disorder	Likely pathogenic	rs2519674440	RCV003402113	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Syndromic X-linked intellectual disability Siderius type	Likely pathogenic; Pathogenic	rs2519516307, rs2519528965, rs2519660069, rs121918522, rs121918523, rs121918524, rs2519674603, rs2519312896, rs1057518729, rs1603305030, rs2065126287, rs2065590491	RCV005603771 RCV003142418 RCV000011544 RCV000011545 RCV000011546 View all (7 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Adrenocortical carcinoma, hereditary	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED, SYNDROMIC, SIDERIUS TYPE	—	HPO	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL OR BEHAVIOURAL DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED INTELLECTUAL DISABILITY SIDERIUS TYPE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED INTELLECTUAL DISABILITY, SIDERIUS TYPE	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (69)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute Promyelocytic Leukemia	Promyelocytic Leukemia	BEFREE	23518351		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	BEFREE	27689328		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	29330049		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety Disorder	BEFREE	28485378		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety Disorders	Anxiety Disorder	BEFREE	28485378		★★★★★ ★☆☆☆☆ Found in Text Mining only
Aortic Valve Insufficiency	Aortic Valve Insufficiency	BEFREE	27689328		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	BEFREE	18498374		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	LHGDN	18498374		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	27183383, 27899639		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	40427554	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	30180906, 32441881	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	25065740		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	37531433	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cleft Lip	Cleft lip	Pubtator	17594395, 19843542, 20067792	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cleft Palate	Cleft palate	Pubtator	19843542	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cleft palate and bilateral cleft lip	Cleft Palate And Bilateral Cleft Lip	BEFREE	19843542		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognitive disorder	BEFREE	29317619		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	28765946		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	28765946, 39810713	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Abnormalities	Congenital abnormalities	Pubtator	19843542	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cryptorchidism	Cryptorchidism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	28485378		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dysmorphic features	Dysmorphic Features	CLINVAR_DG	16199551, 17594395, 17661819, 18498374, 19843542, 20622853, 25167861		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dysmorphic features	Dysmorphic Features	BEFREE	19843542		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	27183383	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	28485378, 29317619		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	16199551, 17661819, 19843542, 23092983, 31691806		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual Disability	Intellectual developmental disorder	Pubtator	17594395, 19843542, 20067792, 23092983, 31906484	Associate	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual Disability	Mental retardation	HPO_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
leukemia	Leukemia	BEFREE	25065740		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	30180906, 30404655, 30764899, 31666106		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	28592245, 38165927	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	28765946	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	27183383, 27899639		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	25065740		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	22120715, 22867098, 27689328		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	28401003		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	22120715, 25065740, 28430394, 28734980, 28765946, 30764899		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	28485378		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental disorders	Mental Disorders	GWASDB_DG	21057379		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental disorders	Mental Disorders	GWASCAT_DG	21057379		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation	Mental retardation	BEFREE	16199551, 17661819, 19843542		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation	Mental retardation	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked	Mental retardation	BEFREE	16199551, 17594395, 17661819, 20101266, 20346720, 20548336, 20622853, 25853498, 27183383, 28126843		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked	Mental retardation	LHGDN	16199551, 17661819, 18498374		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mild Mental Retardation	Mental retardation	BEFREE	25258334		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mild Mental Retardation	Mental retardation	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple congenital anomalies	Multiple Congenital Anomalies	CLINVAR_DG	16199551, 17594395, 17661819, 18498374, 19843542, 20622853, 25167861		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	28401003, 29330049, 30180906, 30764899		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodevelopmental Disorders	Neurodevelopmental Disorders	BEFREE	26077434, 31691806		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	25065740		★★★★★ ★☆☆☆☆ Found in Text Mining only
Polydactyly preaxial type 1	Polydactyly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	22120715, 22867098, 27689328		★★★★★ ★☆☆☆☆ Found in Text Mining only
Psychotic Disorders	Psychosis	GWASDB_DG	21057379		★★★★★ ★☆☆☆☆ Found in Text Mining only
Psychotic Disorders	Psychosis	GWASCAT_DG	21057379		★★★★★ ★☆☆☆☆ Found in Text Mining only
Scoliosis, unspecified	Scoliosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Siderius X-linked mental retardation syndrome	Syndromic Mental Retardation, X-Linked	CLINGEN_DG	16199551, 17594395, 17661819, 20346720, 20548336, 20622853, 25167861, 26633542, 29276005, 29317619		★★★★★ ★☆☆☆☆ Found in Text Mining only
Siderius X-linked mental retardation syndrome	Syndromic Mental Retardation, X-Linked	UNIPROT_DG	16199551, 17661819, 20101266, 20208542, 20346720, 20421419, 20548336, 20622853, 20622854		★★★★★ ★☆☆☆☆ Found in Text Mining only
Siderius X-linked mental retardation syndrome	Syndromic Mental Retardation, X-Linked	ORPHANET_DG	17661819		★★★★★ ★☆☆☆☆ Found in Text Mining only
Siderius X-linked mental retardation syndrome	Syndromic Mental Retardation, X-Linked	GENOMICS_ENGLAND_DG	17661819		★★★★★ ★☆☆☆☆ Found in Text Mining only
Siderius X-linked mental retardation syndrome	Syndromic Mental Retardation, X-Linked	BEFREE	18498374		★★★★★ ★☆☆☆☆ Found in Text Mining only
Siderius X-linked mental retardation syndrome	Syndromic Mental Retardation, X-Linked	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Siderius X-linked mental retardation syndrome	Syndromic Mental Retardation, X-Linked	CTD_human_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	24146981, 25065740		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	28401003		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	33111613	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Synophrys	Synophrys	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Uranostaphyloschisis	Uranostaphyloschisis	BEFREE	25258334		★★★★★ ★☆☆☆☆ Found in Text Mining only
X-linked intellectual disability, Siderius type	Mental Retardation, X-Linked	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

PHF8 (PHD finger protein 8)