Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23101
Gene name	MCF.2 cell line derived transforming sequence-like 2
Gene symbol	MCF2L2
Synonyms (NCBI Gene)	ARHGEF22
Chromosome	3
Chromosome location	3q27.1

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miRTarBase ID	miRNA	Experiments	Reference
MIRT694441	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT694440	hsa-miR-25-3p	HITS-CLIP	23313552
MIRT694439	hsa-miR-32-5p	HITS-CLIP	23313552
MIRT694438	hsa-miR-363-3p	HITS-CLIP	23313552
MIRT694437	hsa-miR-367-3p	HITS-CLIP	23313552
MIRT694436	hsa-miR-92a-3p	HITS-CLIP	23313552
MIRT694435	hsa-miR-92b-3p	HITS-CLIP	23313552
MIRT694434	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT694433	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT694432	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT694431	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT694430	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT694429	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT694428	hsa-miR-767-5p	HITS-CLIP	23313552
MIRT694427	hsa-miR-661	HITS-CLIP	23313552
MIRT694426	hsa-miR-542-3p	HITS-CLIP	23313552
MIRT694425	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT694424	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT694423	hsa-miR-500a-3p	HITS-CLIP	23313552
MIRT694422	hsa-miR-7703	HITS-CLIP	23313552
MIRT694421	hsa-miR-1262	HITS-CLIP	23313552
MIRT694420	hsa-miR-4701-3p	HITS-CLIP	23313552
MIRT694419	hsa-miR-6736-5p	HITS-CLIP	23313552
MIRT673506	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT673505	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT673504	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT673503	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT673502	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT673500	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT673501	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT673499	hsa-miR-7977	HITS-CLIP	23313552
MIRT673498	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT673497	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT673496	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT673495	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT673494	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT673493	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT673492	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT673491	hsa-miR-3689c	HITS-CLIP	23313552
MIRT673490	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT673489	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT673488	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT673487	hsa-miR-3122	HITS-CLIP	23313552
MIRT673486	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT673485	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT673484	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT551298	hsa-miR-302f	HITS-CLIP	23706177
MIRT681424	hsa-miR-890	HITS-CLIP	23706177
MIRT551297	hsa-miR-6888-5p	HITS-CLIP	23706177
MIRT551296	hsa-miR-3929	HITS-CLIP	23706177
MIRT551295	hsa-miR-4419b	HITS-CLIP	23706177
MIRT551294	hsa-miR-4478	HITS-CLIP	23706177
MIRT551292	hsa-miR-7162-3p	HITS-CLIP	23706177
MIRT551291	hsa-miR-219b-3p	HITS-CLIP	23706177
MIRT551289	hsa-miR-485-5p	HITS-CLIP	23706177
MIRT551288	hsa-miR-6884-5p	HITS-CLIP	23706177
MIRT551287	hsa-let-7a-5p	HITS-CLIP	23706177
MIRT551286	hsa-let-7b-5p	HITS-CLIP	23706177
MIRT551285	hsa-let-7c-5p	HITS-CLIP	23706177
MIRT551284	hsa-let-7d-5p	HITS-CLIP	23706177
MIRT551283	hsa-let-7e-5p	HITS-CLIP	23706177
MIRT551282	hsa-let-7f-5p	HITS-CLIP	23706177
MIRT551281	hsa-let-7g-5p	HITS-CLIP	23706177
MIRT551280	hsa-let-7i-5p	HITS-CLIP	23706177
MIRT551279	hsa-miR-4458	HITS-CLIP	23706177
MIRT551277	hsa-miR-4500	HITS-CLIP	23706177
MIRT551278	hsa-miR-98-5p	HITS-CLIP	23706177
MIRT551276	hsa-miR-202-3p	HITS-CLIP	23706177
MIRT551274	hsa-miR-7160-5p	HITS-CLIP	23706177
MIRT673505	hsa-miR-7106-5p	HITS-CLIP	23706177
MIRT673504	hsa-miR-149-3p	HITS-CLIP	23706177
MIRT673503	hsa-miR-4728-5p	HITS-CLIP	23706177
MIRT673502	hsa-miR-6785-5p	HITS-CLIP	23706177
MIRT673500	hsa-miR-6883-5p	HITS-CLIP	23706177
MIRT673501	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT551272	hsa-miR-1273e	HITS-CLIP	23706177
MIRT673498	hsa-miR-30c-1-3p	HITS-CLIP	23706177
MIRT673497	hsa-miR-30c-2-3p	HITS-CLIP	23706177
MIRT673496	hsa-miR-6788-5p	HITS-CLIP	23706177
MIRT673495	hsa-miR-1273h-5p	HITS-CLIP	23706177
MIRT673494	hsa-miR-30b-3p	HITS-CLIP	23706177
MIRT673493	hsa-miR-3689a-3p	HITS-CLIP	23706177
MIRT673492	hsa-miR-3689b-3p	HITS-CLIP	23706177
MIRT673491	hsa-miR-3689c	HITS-CLIP	23706177
MIRT673490	hsa-miR-6779-5p	HITS-CLIP	23706177
MIRT673489	hsa-miR-6780a-5p	HITS-CLIP	23706177
MIRT673485	hsa-miR-887-5p	HITS-CLIP	23706177
MIRT551270	hsa-miR-665	HITS-CLIP	23706177
MIRT673506	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT673505	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT673504	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT673503	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT673502	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT673500	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT673501	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT673499	hsa-miR-7977	HITS-CLIP	23824327
MIRT673498	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT673497	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT673496	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT673495	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT673494	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT673493	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT673492	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT673491	hsa-miR-3689c	HITS-CLIP	23824327
MIRT673490	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT673489	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT673488	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT673487	hsa-miR-3122	HITS-CLIP	23824327
MIRT673486	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT673485	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT673484	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT551298	hsa-miR-302f	PAR-CLIP	20371350
MIRT551297	hsa-miR-6888-5p	PAR-CLIP	20371350
MIRT551296	hsa-miR-3929	PAR-CLIP	20371350
MIRT551295	hsa-miR-4419b	PAR-CLIP	20371350
MIRT551294	hsa-miR-4478	PAR-CLIP	20371350
MIRT551293	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT551292	hsa-miR-7162-3p	PAR-CLIP	20371350
MIRT551291	hsa-miR-219b-3p	PAR-CLIP	20371350
MIRT551290	hsa-miR-6087	PAR-CLIP	20371350
MIRT551287	hsa-let-7a-5p	PAR-CLIP	20371350
MIRT551286	hsa-let-7b-5p	PAR-CLIP	20371350
MIRT551285	hsa-let-7c-5p	PAR-CLIP	20371350
MIRT551284	hsa-let-7d-5p	PAR-CLIP	20371350
MIRT551283	hsa-let-7e-5p	PAR-CLIP	20371350
MIRT551282	hsa-let-7f-5p	PAR-CLIP	20371350
MIRT551281	hsa-let-7g-5p	PAR-CLIP	20371350
MIRT551280	hsa-let-7i-5p	PAR-CLIP	20371350
MIRT551279	hsa-miR-4458	PAR-CLIP	20371350
MIRT551277	hsa-miR-4500	PAR-CLIP	20371350
MIRT551278	hsa-miR-98-5p	PAR-CLIP	20371350
MIRT551276	hsa-miR-202-3p	PAR-CLIP	20371350
MIRT551275	hsa-miR-658	PAR-CLIP	20371350
MIRT551274	hsa-miR-7160-5p	PAR-CLIP	20371350
MIRT551273	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT551272	hsa-miR-1273e	PAR-CLIP	20371350
MIRT551271	hsa-miR-4459	PAR-CLIP	20371350
MIRT551270	hsa-miR-665	PAR-CLIP	20371350
MIRT551298	hsa-miR-302f	PAR-CLIP	21572407
MIRT551297	hsa-miR-6888-5p	PAR-CLIP	21572407
MIRT551296	hsa-miR-3929	PAR-CLIP	21572407
MIRT551295	hsa-miR-4419b	PAR-CLIP	21572407
MIRT551294	hsa-miR-4478	PAR-CLIP	21572407
MIRT551293	hsa-miR-1247-3p	PAR-CLIP	21572407
MIRT551292	hsa-miR-7162-3p	PAR-CLIP	21572407
MIRT551291	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT551290	hsa-miR-6087	PAR-CLIP	21572407
MIRT551289	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT551288	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT551287	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT551286	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT551285	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT551284	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT551283	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT551282	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT551281	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT551280	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT551279	hsa-miR-4458	PAR-CLIP	21572407
MIRT551277	hsa-miR-4500	PAR-CLIP	21572407
MIRT551278	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT551276	hsa-miR-202-3p	PAR-CLIP	21572407
MIRT551275	hsa-miR-658	PAR-CLIP	21572407
MIRT551274	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT551273	hsa-miR-25-5p	PAR-CLIP	21572407
MIRT551272	hsa-miR-1273e	PAR-CLIP	21572407
MIRT551271	hsa-miR-4459	PAR-CLIP	21572407
MIRT551270	hsa-miR-665	PAR-CLIP	21572407
MIRT446693	hsa-miR-3923	PAR-CLIP	22100165
MIRT446692	hsa-miR-4738-3p	PAR-CLIP	22100165
MIRT446691	hsa-miR-6895-3p	PAR-CLIP	22100165
MIRT446690	hsa-miR-593-3p	PAR-CLIP	22100165
MIRT446689	hsa-miR-6818-3p	PAR-CLIP	22100165
MIRT446688	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT446693	hsa-miR-3923	PAR-CLIP	22100165
MIRT446692	hsa-miR-4738-3p	PAR-CLIP	22100165
MIRT446691	hsa-miR-6895-3p	PAR-CLIP	22100165
MIRT446690	hsa-miR-593-3p	PAR-CLIP	22100165
MIRT446689	hsa-miR-6818-3p	PAR-CLIP	22100165
MIRT446688	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT694441	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT694440	hsa-miR-25-3p	HITS-CLIP	23313552
MIRT694439	hsa-miR-32-5p	HITS-CLIP	23313552
MIRT694438	hsa-miR-363-3p	HITS-CLIP	23313552
MIRT694437	hsa-miR-367-3p	HITS-CLIP	23313552
MIRT694436	hsa-miR-92a-3p	HITS-CLIP	23313552
MIRT694435	hsa-miR-92b-3p	HITS-CLIP	23313552
MIRT694434	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT694433	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT694432	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT694431	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT694430	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT694429	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT694428	hsa-miR-767-5p	HITS-CLIP	23313552
MIRT694427	hsa-miR-661	HITS-CLIP	23313552
MIRT694426	hsa-miR-542-3p	HITS-CLIP	23313552
MIRT694425	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT694424	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT694423	hsa-miR-500a-3p	HITS-CLIP	23313552
MIRT694422	hsa-miR-7703	HITS-CLIP	23313552
MIRT694421	hsa-miR-1262	HITS-CLIP	23313552
MIRT694420	hsa-miR-4701-3p	HITS-CLIP	23313552
MIRT694419	hsa-miR-6736-5p	HITS-CLIP	23313552
MIRT673506	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT673505	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT673504	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT673503	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT673502	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT673500	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT673501	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT673499	hsa-miR-7977	HITS-CLIP	23313552
MIRT673498	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT673497	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT673496	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT673495	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT673494	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT673493	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT673492	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT673491	hsa-miR-3689c	HITS-CLIP	23313552
MIRT673490	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT673489	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT673488	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT673487	hsa-miR-3122	HITS-CLIP	23313552
MIRT673486	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT673485	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT673484	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT551298	hsa-miR-302f	HITS-CLIP	23706177
MIRT681424	hsa-miR-890	HITS-CLIP	23706177
MIRT551297	hsa-miR-6888-5p	HITS-CLIP	23706177
MIRT551296	hsa-miR-3929	HITS-CLIP	23706177
MIRT551295	hsa-miR-4419b	HITS-CLIP	23706177
MIRT551294	hsa-miR-4478	HITS-CLIP	23706177
MIRT551292	hsa-miR-7162-3p	HITS-CLIP	23706177
MIRT551291	hsa-miR-219b-3p	HITS-CLIP	23706177
MIRT551289	hsa-miR-485-5p	HITS-CLIP	23706177
MIRT551288	hsa-miR-6884-5p	HITS-CLIP	23706177
MIRT551287	hsa-let-7a-5p	HITS-CLIP	23706177
MIRT551286	hsa-let-7b-5p	HITS-CLIP	23706177
MIRT551285	hsa-let-7c-5p	HITS-CLIP	23706177
MIRT551284	hsa-let-7d-5p	HITS-CLIP	23706177
MIRT551283	hsa-let-7e-5p	HITS-CLIP	23706177
MIRT551282	hsa-let-7f-5p	HITS-CLIP	23706177
MIRT551281	hsa-let-7g-5p	HITS-CLIP	23706177
MIRT551280	hsa-let-7i-5p	HITS-CLIP	23706177
MIRT551279	hsa-miR-4458	HITS-CLIP	23706177
MIRT551277	hsa-miR-4500	HITS-CLIP	23706177
MIRT551278	hsa-miR-98-5p	HITS-CLIP	23706177
MIRT551276	hsa-miR-202-3p	HITS-CLIP	23706177
MIRT551274	hsa-miR-7160-5p	HITS-CLIP	23706177
MIRT673505	hsa-miR-7106-5p	HITS-CLIP	23706177
MIRT673504	hsa-miR-149-3p	HITS-CLIP	23706177
MIRT673503	hsa-miR-4728-5p	HITS-CLIP	23706177
MIRT673502	hsa-miR-6785-5p	HITS-CLIP	23706177
MIRT673500	hsa-miR-6883-5p	HITS-CLIP	23706177
MIRT673501	hsa-miR-6799-5p	HITS-CLIP	23706177
MIRT551272	hsa-miR-1273e	HITS-CLIP	23706177
MIRT673498	hsa-miR-30c-1-3p	HITS-CLIP	23706177
MIRT673497	hsa-miR-30c-2-3p	HITS-CLIP	23706177
MIRT673496	hsa-miR-6788-5p	HITS-CLIP	23706177
MIRT673495	hsa-miR-1273h-5p	HITS-CLIP	23706177
MIRT673494	hsa-miR-30b-3p	HITS-CLIP	23706177
MIRT673493	hsa-miR-3689a-3p	HITS-CLIP	23706177
MIRT673492	hsa-miR-3689b-3p	HITS-CLIP	23706177
MIRT673491	hsa-miR-3689c	HITS-CLIP	23706177
MIRT673490	hsa-miR-6779-5p	HITS-CLIP	23706177
MIRT673489	hsa-miR-6780a-5p	HITS-CLIP	23706177
MIRT673485	hsa-miR-887-5p	HITS-CLIP	23706177
MIRT551270	hsa-miR-665	HITS-CLIP	23706177
MIRT673506	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT673505	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT673504	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT673503	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT673502	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT673500	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT673501	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT673499	hsa-miR-7977	HITS-CLIP	23824327
MIRT673498	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT673497	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT673496	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT673495	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT673494	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT673493	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT673492	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT673491	hsa-miR-3689c	HITS-CLIP	23824327
MIRT673490	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT673489	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT673488	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT673487	hsa-miR-3122	HITS-CLIP	23824327
MIRT673486	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT673485	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT673484	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT551298	hsa-miR-302f	PAR-CLIP	20371350
MIRT551297	hsa-miR-6888-5p	PAR-CLIP	20371350
MIRT551296	hsa-miR-3929	PAR-CLIP	20371350
MIRT551295	hsa-miR-4419b	PAR-CLIP	20371350
MIRT551294	hsa-miR-4478	PAR-CLIP	20371350
MIRT551293	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT551292	hsa-miR-7162-3p	PAR-CLIP	20371350
MIRT551291	hsa-miR-219b-3p	PAR-CLIP	20371350
MIRT551290	hsa-miR-6087	PAR-CLIP	20371350
MIRT551287	hsa-let-7a-5p	PAR-CLIP	20371350
MIRT551286	hsa-let-7b-5p	PAR-CLIP	20371350
MIRT551285	hsa-let-7c-5p	PAR-CLIP	20371350
MIRT551284	hsa-let-7d-5p	PAR-CLIP	20371350
MIRT551283	hsa-let-7e-5p	PAR-CLIP	20371350
MIRT551282	hsa-let-7f-5p	PAR-CLIP	20371350
MIRT551281	hsa-let-7g-5p	PAR-CLIP	20371350
MIRT551280	hsa-let-7i-5p	PAR-CLIP	20371350
MIRT551279	hsa-miR-4458	PAR-CLIP	20371350
MIRT551277	hsa-miR-4500	PAR-CLIP	20371350
MIRT551278	hsa-miR-98-5p	PAR-CLIP	20371350
MIRT551276	hsa-miR-202-3p	PAR-CLIP	20371350
MIRT551275	hsa-miR-658	PAR-CLIP	20371350
MIRT551274	hsa-miR-7160-5p	PAR-CLIP	20371350
MIRT551273	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT551272	hsa-miR-1273e	PAR-CLIP	20371350
MIRT551271	hsa-miR-4459	PAR-CLIP	20371350
MIRT551270	hsa-miR-665	PAR-CLIP	20371350
MIRT551298	hsa-miR-302f	PAR-CLIP	21572407
MIRT551297	hsa-miR-6888-5p	PAR-CLIP	21572407
MIRT551296	hsa-miR-3929	PAR-CLIP	21572407
MIRT551295	hsa-miR-4419b	PAR-CLIP	21572407
MIRT551294	hsa-miR-4478	PAR-CLIP	21572407
MIRT551293	hsa-miR-1247-3p	PAR-CLIP	21572407
MIRT551292	hsa-miR-7162-3p	PAR-CLIP	21572407
MIRT551291	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT551290	hsa-miR-6087	PAR-CLIP	21572407
MIRT551289	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT551288	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT551287	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT551286	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT551285	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT551284	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT551283	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT551282	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT551281	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT551280	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT551279	hsa-miR-4458	PAR-CLIP	21572407
MIRT551277	hsa-miR-4500	PAR-CLIP	21572407
MIRT551278	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT551276	hsa-miR-202-3p	PAR-CLIP	21572407
MIRT551275	hsa-miR-658	PAR-CLIP	21572407
MIRT551274	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT551273	hsa-miR-25-5p	PAR-CLIP	21572407
MIRT551272	hsa-miR-1273e	PAR-CLIP	21572407
MIRT551271	hsa-miR-4459	PAR-CLIP	21572407
MIRT551270	hsa-miR-665	PAR-CLIP	21572407
MIRT446693	hsa-miR-3923	PAR-CLIP	22100165
MIRT446692	hsa-miR-4738-3p	PAR-CLIP	22100165
MIRT446691	hsa-miR-6895-3p	PAR-CLIP	22100165
MIRT446690	hsa-miR-593-3p	PAR-CLIP	22100165
MIRT446689	hsa-miR-6818-3p	PAR-CLIP	22100165
MIRT446688	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT446693	hsa-miR-3923	PAR-CLIP	22100165
MIRT446692	hsa-miR-4738-3p	PAR-CLIP	22100165
MIRT446691	hsa-miR-6895-3p	PAR-CLIP	22100165
MIRT446690	hsa-miR-593-3p	PAR-CLIP	22100165
MIRT446689	hsa-miR-6818-3p	PAR-CLIP	22100165
MIRT446688	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT1136807	hsa-miR-1197	CLIP-seq
MIRT1136808	hsa-miR-1268	CLIP-seq
MIRT1136809	hsa-miR-1268b	CLIP-seq
MIRT1136810	hsa-miR-1827	CLIP-seq
MIRT1136811	hsa-miR-1908	CLIP-seq
MIRT1136812	hsa-miR-2114	CLIP-seq
MIRT1136813	hsa-miR-3664-3p	CLIP-seq
MIRT1136814	hsa-miR-4433	CLIP-seq
MIRT1136815	hsa-miR-4436a	CLIP-seq
MIRT1136816	hsa-miR-4649-3p	CLIP-seq
MIRT1136817	hsa-miR-4668-3p	CLIP-seq
MIRT1136818	hsa-miR-4684-5p	CLIP-seq
MIRT1136819	hsa-miR-4695-5p	CLIP-seq
MIRT1136820	hsa-miR-4722-5p	CLIP-seq
MIRT1136821	hsa-miR-4767	CLIP-seq
MIRT1136822	hsa-miR-4768-3p	CLIP-seq
MIRT1136823	hsa-miR-4786-5p	CLIP-seq
MIRT1136824	hsa-miR-4793-5p	CLIP-seq
MIRT1136825	hsa-miR-4794	CLIP-seq
MIRT1136826	hsa-miR-510	CLIP-seq
MIRT1136827	hsa-miR-512-5p	CLIP-seq
MIRT1136828	hsa-miR-548c-3p	CLIP-seq
MIRT1136829	hsa-miR-566	CLIP-seq
MIRT1136830	hsa-miR-602	CLIP-seq
MIRT1136831	hsa-miR-663	CLIP-seq
MIRT1136832	hsa-miR-940	CLIP-seq
MIRT1551186	hsa-miR-1228	CLIP-seq
MIRT1551187	hsa-miR-1273	CLIP-seq
MIRT1551188	hsa-miR-4486	CLIP-seq
MIRT1551189	hsa-miR-4649-5p	CLIP-seq
MIRT1551190	hsa-miR-766	CLIP-seq
MIRT2038905	hsa-miR-1207-5p	CLIP-seq
MIRT1551186	hsa-miR-1228	CLIP-seq
MIRT1551187	hsa-miR-1273	CLIP-seq
MIRT1136812	hsa-miR-2114	CLIP-seq
MIRT2038906	hsa-miR-3132	CLIP-seq
MIRT1136813	hsa-miR-3664-3p	CLIP-seq
MIRT1136814	hsa-miR-4433	CLIP-seq
MIRT2038907	hsa-miR-4451	CLIP-seq
MIRT1551188	hsa-miR-4486	CLIP-seq
MIRT1551189	hsa-miR-4649-5p	CLIP-seq
MIRT1136819	hsa-miR-4695-5p	CLIP-seq
MIRT2038908	hsa-miR-4727-3p	CLIP-seq
MIRT2038909	hsa-miR-4763-3p	CLIP-seq
MIRT1136822	hsa-miR-4768-3p	CLIP-seq
MIRT1136826	hsa-miR-510	CLIP-seq
MIRT1136827	hsa-miR-512-5p	CLIP-seq
MIRT1551190	hsa-miR-766	CLIP-seq
MIRT2038905	hsa-miR-1207-5p	CLIP-seq
MIRT1551186	hsa-miR-1228	CLIP-seq
MIRT1136808	hsa-miR-1268	CLIP-seq
MIRT1136809	hsa-miR-1268b	CLIP-seq
MIRT1551187	hsa-miR-1273	CLIP-seq
MIRT1136810	hsa-miR-1827	CLIP-seq
MIRT1136811	hsa-miR-1908	CLIP-seq
MIRT2268880	hsa-miR-1909	CLIP-seq
MIRT1136812	hsa-miR-2114	CLIP-seq
MIRT1136813	hsa-miR-3664-3p	CLIP-seq
MIRT1136814	hsa-miR-4433	CLIP-seq
MIRT1551188	hsa-miR-4486	CLIP-seq
MIRT2268881	hsa-miR-4525	CLIP-seq
MIRT2268882	hsa-miR-4537	CLIP-seq
MIRT1136816	hsa-miR-4649-3p	CLIP-seq
MIRT1551189	hsa-miR-4649-5p	CLIP-seq
MIRT1136819	hsa-miR-4695-5p	CLIP-seq
MIRT2268883	hsa-miR-4716-3p	CLIP-seq
MIRT1136820	hsa-miR-4722-5p	CLIP-seq
MIRT2038909	hsa-miR-4763-3p	CLIP-seq
MIRT1136821	hsa-miR-4767	CLIP-seq
MIRT1136822	hsa-miR-4768-3p	CLIP-seq
MIRT1136826	hsa-miR-510	CLIP-seq
MIRT1136827	hsa-miR-512-5p	CLIP-seq
MIRT1136829	hsa-miR-566	CLIP-seq
MIRT1136831	hsa-miR-663	CLIP-seq
MIRT1551190	hsa-miR-766	CLIP-seq
MIRT1136832	hsa-miR-940	CLIP-seq
MIRT1551186	hsa-miR-1228	CLIP-seq
MIRT1551187	hsa-miR-1273	CLIP-seq
MIRT1136810	hsa-miR-1827	CLIP-seq
MIRT1136813	hsa-miR-3664-3p	CLIP-seq
MIRT1136814	hsa-miR-4433	CLIP-seq
MIRT1551188	hsa-miR-4486	CLIP-seq
MIRT1136816	hsa-miR-4649-3p	CLIP-seq
MIRT1551189	hsa-miR-4649-5p	CLIP-seq
MIRT1136819	hsa-miR-4695-5p	CLIP-seq
MIRT1136820	hsa-miR-4722-5p	CLIP-seq
MIRT1136822	hsa-miR-4768-3p	CLIP-seq
MIRT1136826	hsa-miR-510	CLIP-seq
MIRT1136827	hsa-miR-512-5p	CLIP-seq
MIRT1551190	hsa-miR-766	CLIP-seq
MIRT1136832	hsa-miR-940	CLIP-seq
MIRT2038906	hsa-miR-3132	CLIP-seq
MIRT2038907	hsa-miR-4451	CLIP-seq
MIRT2038908	hsa-miR-4727-3p	CLIP-seq
MIRT2038905	hsa-miR-1207-5p	CLIP-seq
MIRT1551187	hsa-miR-1273	CLIP-seq
MIRT1136810	hsa-miR-1827	CLIP-seq
MIRT2268880	hsa-miR-1909	CLIP-seq
MIRT2038906	hsa-miR-3132	CLIP-seq
MIRT1136814	hsa-miR-4433	CLIP-seq
MIRT2038907	hsa-miR-4451	CLIP-seq
MIRT1551188	hsa-miR-4486	CLIP-seq
MIRT2268881	hsa-miR-4525	CLIP-seq
MIRT1551189	hsa-miR-4649-5p	CLIP-seq
MIRT2568330	hsa-miR-4683	CLIP-seq
MIRT1136818	hsa-miR-4684-5p	CLIP-seq
MIRT2268883	hsa-miR-4716-3p	CLIP-seq
MIRT2038908	hsa-miR-4727-3p	CLIP-seq
MIRT2038909	hsa-miR-4763-3p	CLIP-seq
MIRT1136822	hsa-miR-4768-3p	CLIP-seq
MIRT1136823	hsa-miR-4786-5p	CLIP-seq
MIRT1136824	hsa-miR-4793-5p	CLIP-seq
MIRT1136825	hsa-miR-4794	CLIP-seq
MIRT1136830	hsa-miR-602	CLIP-seq
MIRT1551190	hsa-miR-766	CLIP-seq
MIRT1136832	hsa-miR-940	CLIP-seq
MIRT2038905	hsa-miR-1207-5p	CLIP-seq
MIRT1136810	hsa-miR-1827	CLIP-seq
MIRT2268880	hsa-miR-1909	CLIP-seq
MIRT1136814	hsa-miR-4433	CLIP-seq
MIRT2268881	hsa-miR-4525	CLIP-seq
MIRT2568330	hsa-miR-4683	CLIP-seq
MIRT2268883	hsa-miR-4716-3p	CLIP-seq
MIRT2038909	hsa-miR-4763-3p	CLIP-seq
MIRT1136822	hsa-miR-4768-3p	CLIP-seq
MIRT1136823	hsa-miR-4786-5p	CLIP-seq
MIRT1136824	hsa-miR-4793-5p	CLIP-seq
MIRT1136825	hsa-miR-4794	CLIP-seq
MIRT1136832	hsa-miR-940	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005829	Component	Cytosol	IEA

MIM	HGNC	e!Ensembl
619946	30319	ENSG00000053524

Q86YR7

Protein name

Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2)

Protein function

Probably functions as a guanine nucleotide exchange factor.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13716	CRAL_TRIO_2	60 → 194	Divergent CRAL/TRIO domain	Domain
PF00621	RhoGEF	623 → 820	RhoGEF domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Significantly expressed in brain and modestly in pancreas, brain and testis. {ECO:0000269|PubMed:18259684}.

Sequence

MLSCLKEEMPPQELTRRLATVITHVDEIMQQEVRPLMAVEIIEQLHRQFAILSGGRGEDG
APIITFPEFSGFKHIPDEDFLNVMTYLTSIPSVEAASIGFIVVIDRRRDKWSSVKASLTR
IAVAFPGNLQLIFILRPSRFIQRTFTDIGIKYYRNEFKTKVPIIMVNSVSDLHGYIDKSQ
LTRELGGTLEYRHGQWVNHRTAIENFALTLKTTAQMLQTFGSCLATAELPRSMLSTEDLL
MSHTRQRDKLQDELKLLGKQGTTLLSCIQEPATKCPNSKLNLNQLENVTTMERLLVQLDE
TEKAFSHFWSEHHLKLNQCLQLQHFEHDFCKAKLALDNLLEEQAEFTGIGDSVMHVEQIL
KEHKKLEEKSQEPLEKAQLLALVGDQLIQSHHYAADAIRPRCVELRHLCDDFINGNKKKW
DILGKSLEFHRQLDKVSQWCEAGIYLLASQAVDKCQSREGVDIALNDIATFLGTVKEYPL
LSPKEFYNEFELLLTLDAKAKAQKVLQRLDDVQEIFHKRQVSLMKLAAKQTRPVQPVAPH
PESSPKWVSSKTSQPSTSVPLARPLRTSEEPYTETELNSRGKEDDETKFEVKSEEIFESH
HERGNPELEQQARLGDLSPRRRIIRDLLETEEIYIKEIKSIIDGYITPMDFIWLKHLIPD
VLQNNKDFLFGNIRELYEFHNRTFLKELEKCAENPELLAHCFLKRKEDLQIYFKYHKNLP
RARAIWQECQDCAYFGVCQRQLDHNLPLFKYLKGPSQRLIKYQMLLKGLLDFESPEDMEI
DPGELGGSAKDGPKRTKDSAFSTELQQALAVIEDLIKSCELAVDLAAVTECPDDIGKLGK
LLLHGPFSVWTIHKDRYKMKDLIRFKPSQRQIYLFERGIVFCKIRMEPGDQGLSPHYSFK
KTMKLMTLSIRQLGRGSHRKFEIASRNGLEKYILQAASKEIRDCWFSEISKLLMEQQNNI
KDQGNPQFEMSTSKGSGAGSGPWIKNMERATTSKEDPASSTGGIKGCSSREFSSMDTFED
CEGAEDMEKESSALSLAGLFQSDDSHETCSSKSAFLERGESSQGEKEERDEEETATRSTE
EERAGASTGRLAPAGATAGFQARALRPRTSAQES

Sequence length

1114

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CHRONIC KIDNEY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTROPHIC CARDIOMYOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KIDNEY FAILURE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MICROPHTHALMIA, SYNDROMIC 3	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (34)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Aortic Aneurysm, Abdominal	Aortic Aneurysm	BEFREE	30745030		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	28845052		★★★★★ ★☆☆☆☆ Found in Text Mining only
Choroid Plexus Papilloma	Choroid Plexus Papilloma	BEFREE	30067887		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	30065662		★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	29474860		★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	31601968		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 1	Diabetes mellitus, type 1	Pubtator	20667095	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	20667095		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathies	Diabetic neuropathy	Pubtator	20667095	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	BEFREE	20667095		★★★★★ ★☆☆☆☆ Found in Text Mining only
Erythromelalgia	Erythromelalgia	BEFREE	17239250		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gastroesophageal reflux disease	Gastroesophageal Reflux Disease	BEFREE	29597000		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Diseases	Heart disease	Pubtator	32152362	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	28385191		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	29747650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney Disease	BEFREE	20667095		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	20667095	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	31518645		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Liver Cirrhosis	BEFREE	28701025		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Bone Neoplasm	Malignant Bone Neoplasm	BEFREE	31015342		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	28845052		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Malnutrition	Malnutrition	BEFREE	31338008		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	31601968		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial Ischemia	BEFREE	30065662		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	23382806, 31419255		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuropathy	Neuropathy	BEFREE	27343803, 29339292, 30076959, 30887907, 31379513		★★★★★ ★☆☆☆☆ Found in Text Mining only
PAROXYSMAL EXTREME PAIN DISORDER	Paroxysmal extreme pain disorder	BEFREE	18803825		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Nervous System Diseases	Nervous System Diseases	BEFREE	28181561		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peripheral Neuropathy	Peripheral Neuropathy	BEFREE	28181561		★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	BEFREE	19648752		★★★★★ ★☆☆☆☆ Found in Text Mining only
Primary Erythermalgia	Erythermalgia	BEFREE	28990532		★★★★★ ★☆☆☆☆ Found in Text Mining only
Varicosity	Vulval varices	BEFREE	28075022, 29484823		★★★★★ ★☆☆☆☆ Found in Text Mining only

MCF2L2 (MCF.2 cell line derived transforming sequence-like 2)