Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23036
Gene name	Zinc finger protein 292
Gene symbol	ZNF292
Synonyms (NCBI Gene)	MRD63MRD64Nbla00365ZFP292ZN-16Zn-15bA393I2.3
Chromosome	6
Chromosome location	6q14.3
Summary	This gene encodes a growth hormone-dependent, zinc finger transcription factor that functions as a tumor suppressor. Naturally occurring mutations in this gene are associated with gastric cancer, colorectal cancer, and chronic lymphocytic leukemia. [provi

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1135401779	AAGA>-	Pathogenic	Coding sequence variant, frameshift variant
rs1554208945	A>C	Likely-pathogenic	Missense variant, coding sequence variant

268

Show/Hide all (268)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018531	hsa-miR-335-5p	Microarray	18185580
MIRT030961	hsa-miR-21-5p	Microarray	18591254
MIRT717473	hsa-miR-5003-3p	HITS-CLIP	19536157
MIRT717472	hsa-miR-7151-5p	HITS-CLIP	19536157
MIRT717471	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT717470	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT717469	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT717468	hsa-miR-4795-3p	HITS-CLIP	19536157
MIRT717467	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT682941	hsa-miR-141-3p	HITS-CLIP	23706177
MIRT682940	hsa-miR-200a-3p	HITS-CLIP	23706177
MIRT682939	hsa-miR-508-5p	HITS-CLIP	23706177
MIRT682938	hsa-miR-6849-3p	HITS-CLIP	23706177
MIRT682937	hsa-miR-939-3p	HITS-CLIP	23706177
MIRT682936	hsa-miR-766-3p	HITS-CLIP	23706177
MIRT682935	hsa-miR-4793-3p	HITS-CLIP	23706177
MIRT682934	hsa-miR-1285-3p	HITS-CLIP	23706177
MIRT682933	hsa-miR-3187-5p	HITS-CLIP	23706177
MIRT682932	hsa-miR-5189-5p	HITS-CLIP	23706177
MIRT682931	hsa-miR-612	HITS-CLIP	23706177
MIRT682930	hsa-miR-6860	HITS-CLIP	23706177
MIRT682929	hsa-miR-661	HITS-CLIP	23706177
MIRT408854	hsa-miR-196a-3p	HITS-CLIP	23706177
MIRT682928	hsa-miR-6512-3p	HITS-CLIP	23706177
MIRT682927	hsa-miR-6720-5p	HITS-CLIP	23706177
MIRT682926	hsa-miR-7703	HITS-CLIP	23706177
MIRT682925	hsa-miR-1273g-3p	HITS-CLIP	23706177
MIRT532948	hsa-miR-32-3p	PAR-CLIP	22012620
MIRT532947	hsa-miR-3120-3p	PAR-CLIP	22012620
MIRT532946	hsa-miR-3925-5p	PAR-CLIP	22012620
MIRT532945	hsa-miR-146a-5p	PAR-CLIP	22012620
MIRT532944	hsa-miR-146b-5p	PAR-CLIP	22012620
MIRT532943	hsa-miR-7153-5p	PAR-CLIP	22012620
MIRT717473	hsa-miR-5003-3p	HITS-CLIP	19536157
MIRT717472	hsa-miR-7151-5p	HITS-CLIP	19536157
MIRT717471	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT717470	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT717469	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT717468	hsa-miR-4795-3p	HITS-CLIP	19536157
MIRT717467	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT682941	hsa-miR-141-3p	HITS-CLIP	23706177
MIRT682940	hsa-miR-200a-3p	HITS-CLIP	23706177
MIRT682939	hsa-miR-508-5p	HITS-CLIP	23706177
MIRT682938	hsa-miR-6849-3p	HITS-CLIP	23706177
MIRT682937	hsa-miR-939-3p	HITS-CLIP	23706177
MIRT682936	hsa-miR-766-3p	HITS-CLIP	23706177
MIRT682935	hsa-miR-4793-3p	HITS-CLIP	23706177
MIRT682934	hsa-miR-1285-3p	HITS-CLIP	23706177
MIRT682933	hsa-miR-3187-5p	HITS-CLIP	23706177
MIRT682932	hsa-miR-5189-5p	HITS-CLIP	23706177
MIRT682931	hsa-miR-612	HITS-CLIP	23706177
MIRT682930	hsa-miR-6860	HITS-CLIP	23706177
MIRT682929	hsa-miR-661	HITS-CLIP	23706177
MIRT408854	hsa-miR-196a-3p	HITS-CLIP	23706177
MIRT682928	hsa-miR-6512-3p	HITS-CLIP	23706177
MIRT682927	hsa-miR-6720-5p	HITS-CLIP	23706177
MIRT682926	hsa-miR-7703	HITS-CLIP	23706177
MIRT682925	hsa-miR-1273g-3p	HITS-CLIP	23706177
MIRT532948	hsa-miR-32-3p	PAR-CLIP	22012620
MIRT532947	hsa-miR-3120-3p	PAR-CLIP	22012620
MIRT532946	hsa-miR-3925-5p	PAR-CLIP	22012620
MIRT532945	hsa-miR-146a-5p	PAR-CLIP	22012620
MIRT532944	hsa-miR-146b-5p	PAR-CLIP	22012620
MIRT532943	hsa-miR-7153-5p	PAR-CLIP	22012620
MIRT1521346	hsa-miR-1193	CLIP-seq
MIRT1521347	hsa-miR-1207-5p	CLIP-seq
MIRT1521348	hsa-miR-124	CLIP-seq
MIRT1521349	hsa-miR-1290	CLIP-seq
MIRT1521350	hsa-miR-1304	CLIP-seq
MIRT1521351	hsa-miR-132	CLIP-seq
MIRT1521352	hsa-miR-151-3p	CLIP-seq
MIRT1521353	hsa-miR-183	CLIP-seq
MIRT1521354	hsa-miR-197	CLIP-seq
MIRT1521355	hsa-miR-200b	CLIP-seq
MIRT1521356	hsa-miR-200c	CLIP-seq
MIRT1521357	hsa-miR-203	CLIP-seq
MIRT1521358	hsa-miR-212	CLIP-seq
MIRT1521359	hsa-miR-23a	CLIP-seq
MIRT1521360	hsa-miR-23b	CLIP-seq
MIRT1521361	hsa-miR-23c	CLIP-seq
MIRT1521362	hsa-miR-302a	CLIP-seq
MIRT1521363	hsa-miR-302b	CLIP-seq
MIRT1521364	hsa-miR-302c	CLIP-seq
MIRT1521365	hsa-miR-302d	CLIP-seq
MIRT1521366	hsa-miR-302e	CLIP-seq
MIRT1521367	hsa-miR-3074-5p	CLIP-seq
MIRT1521368	hsa-miR-3123	CLIP-seq
MIRT1521369	hsa-miR-3156-5p	CLIP-seq
MIRT1521370	hsa-miR-3163	CLIP-seq
MIRT1521371	hsa-miR-3187-3p	CLIP-seq
MIRT1521372	hsa-miR-330-3p	CLIP-seq
MIRT1521373	hsa-miR-338-5p	CLIP-seq
MIRT1521374	hsa-miR-3671	CLIP-seq
MIRT1521375	hsa-miR-3690	CLIP-seq
MIRT1521376	hsa-miR-3714	CLIP-seq
MIRT1521377	hsa-miR-372	CLIP-seq
MIRT1521378	hsa-miR-373	CLIP-seq
MIRT1521379	hsa-miR-378g	CLIP-seq
MIRT1521380	hsa-miR-3910	CLIP-seq
MIRT1521381	hsa-miR-3977	CLIP-seq
MIRT1521382	hsa-miR-4254	CLIP-seq
MIRT1521383	hsa-miR-4284	CLIP-seq
MIRT1521384	hsa-miR-429	CLIP-seq
MIRT1521385	hsa-miR-4307	CLIP-seq
MIRT1521386	hsa-miR-4417	CLIP-seq
MIRT1521387	hsa-miR-4435	CLIP-seq
MIRT1521388	hsa-miR-4436b-3p	CLIP-seq
MIRT1521389	hsa-miR-4437	CLIP-seq
MIRT1521390	hsa-miR-4470	CLIP-seq
MIRT1521391	hsa-miR-4477b	CLIP-seq
MIRT1521392	hsa-miR-455-5p	CLIP-seq
MIRT1521393	hsa-miR-4668-3p	CLIP-seq
MIRT1521394	hsa-miR-4674	CLIP-seq
MIRT1521395	hsa-miR-4686	CLIP-seq
MIRT1521396	hsa-miR-4699-3p	CLIP-seq
MIRT1521397	hsa-miR-4701-5p	CLIP-seq
MIRT1521398	hsa-miR-4717-3p	CLIP-seq
MIRT1521399	hsa-miR-4719	CLIP-seq
MIRT1521400	hsa-miR-4729	CLIP-seq
MIRT1521401	hsa-miR-4760-3p	CLIP-seq
MIRT1521402	hsa-miR-4763-3p	CLIP-seq
MIRT1521403	hsa-miR-4775	CLIP-seq
MIRT1521404	hsa-miR-506	CLIP-seq
MIRT1521405	hsa-miR-513b	CLIP-seq
MIRT1521406	hsa-miR-519a	CLIP-seq
MIRT1521407	hsa-miR-519b-3p	CLIP-seq
MIRT1521408	hsa-miR-519c-3p	CLIP-seq
MIRT1521409	hsa-miR-520a-3p	CLIP-seq
MIRT1521410	hsa-miR-520b	CLIP-seq
MIRT1521411	hsa-miR-520c-3p	CLIP-seq
MIRT1521412	hsa-miR-520d-3p	CLIP-seq
MIRT1521413	hsa-miR-520d-5p	CLIP-seq
MIRT1521414	hsa-miR-520e	CLIP-seq
MIRT1521415	hsa-miR-520f	CLIP-seq
MIRT1521416	hsa-miR-520g	CLIP-seq
MIRT1521417	hsa-miR-520h	CLIP-seq
MIRT1521418	hsa-miR-524-5p	CLIP-seq
MIRT1521419	hsa-miR-548s	CLIP-seq
MIRT1521420	hsa-miR-568	CLIP-seq
MIRT1521421	hsa-miR-579	CLIP-seq
MIRT1521422	hsa-miR-588	CLIP-seq
MIRT1521423	hsa-miR-592	CLIP-seq
MIRT1521424	hsa-miR-597	CLIP-seq
MIRT1521425	hsa-miR-600	CLIP-seq
MIRT1521426	hsa-miR-616	CLIP-seq
MIRT1521427	hsa-miR-633	CLIP-seq
MIRT1521347	hsa-miR-1207-5p	CLIP-seq
MIRT1521349	hsa-miR-1290	CLIP-seq
MIRT1521388	hsa-miR-4436b-3p	CLIP-seq
MIRT1521402	hsa-miR-4763-3p	CLIP-seq
MIRT1521347	hsa-miR-1207-5p	CLIP-seq
MIRT1521349	hsa-miR-1290	CLIP-seq
MIRT1521388	hsa-miR-4436b-3p	CLIP-seq
MIRT1521402	hsa-miR-4763-3p	CLIP-seq
MIRT1521359	hsa-miR-23a	CLIP-seq
MIRT1521360	hsa-miR-23b	CLIP-seq
MIRT1521361	hsa-miR-23c	CLIP-seq
MIRT1521373	hsa-miR-338-5p	CLIP-seq
MIRT1521393	hsa-miR-4668-3p	CLIP-seq
MIRT1521401	hsa-miR-4760-3p	CLIP-seq
MIRT2157427	hsa-miR-4762-5p	CLIP-seq
MIRT2157428	hsa-miR-587	CLIP-seq
MIRT1521347	hsa-miR-1207-5p	CLIP-seq
MIRT2376991	hsa-miR-1273e	CLIP-seq
MIRT1521349	hsa-miR-1290	CLIP-seq
MIRT1521373	hsa-miR-338-5p	CLIP-seq
MIRT2376992	hsa-miR-3646	CLIP-seq
MIRT1521388	hsa-miR-4436b-3p	CLIP-seq
MIRT1521396	hsa-miR-4699-3p	CLIP-seq
MIRT1521402	hsa-miR-4763-3p	CLIP-seq
MIRT2376993	hsa-miR-494	CLIP-seq
MIRT1521405	hsa-miR-513b	CLIP-seq
MIRT2376994	hsa-miR-561	CLIP-seq
MIRT1521421	hsa-miR-579	CLIP-seq
MIRT1521367	hsa-miR-3074-5p	CLIP-seq
MIRT1521385	hsa-miR-4307	CLIP-seq
MIRT1521388	hsa-miR-4436b-3p	CLIP-seq
MIRT2435045	hsa-miR-138	CLIP-seq
MIRT1521373	hsa-miR-338-5p	CLIP-seq
MIRT2435046	hsa-miR-4456	CLIP-seq
MIRT2435047	hsa-miR-4494	CLIP-seq
MIRT2435048	hsa-miR-885-3p	CLIP-seq
MIRT2669264	hsa-miR-1257	CLIP-seq
MIRT2669265	hsa-miR-1269	CLIP-seq
MIRT2669266	hsa-miR-1269b	CLIP-seq
MIRT2669267	hsa-miR-1323	CLIP-seq
MIRT2669268	hsa-miR-1976	CLIP-seq
MIRT1521355	hsa-miR-200b	CLIP-seq
MIRT1521356	hsa-miR-200c	CLIP-seq
MIRT2669269	hsa-miR-2116	CLIP-seq
MIRT2669270	hsa-miR-25	CLIP-seq
MIRT2669271	hsa-miR-3150a-5p	CLIP-seq
MIRT2669272	hsa-miR-3150b-5p	CLIP-seq
MIRT2669273	hsa-miR-32	CLIP-seq
MIRT2669274	hsa-miR-363	CLIP-seq
MIRT2376992	hsa-miR-3646	CLIP-seq
MIRT2669275	hsa-miR-367	CLIP-seq
MIRT1521375	hsa-miR-3690	CLIP-seq
MIRT2669276	hsa-miR-380	CLIP-seq
MIRT2669277	hsa-miR-3974	CLIP-seq
MIRT1521382	hsa-miR-4254	CLIP-seq
MIRT2669278	hsa-miR-4259	CLIP-seq
MIRT1521384	hsa-miR-429	CLIP-seq
MIRT1521385	hsa-miR-4307	CLIP-seq
MIRT2669279	hsa-miR-4495	CLIP-seq
MIRT2669280	hsa-miR-452	CLIP-seq
MIRT2669281	hsa-miR-4529-3p	CLIP-seq
MIRT2669282	hsa-miR-4635	CLIP-seq
MIRT1521393	hsa-miR-4668-3p	CLIP-seq
MIRT2669283	hsa-miR-4676-3p	CLIP-seq
MIRT2669284	hsa-miR-4677-5p	CLIP-seq
MIRT2669285	hsa-miR-4709-3p	CLIP-seq
MIRT2669286	hsa-miR-4715-5p	CLIP-seq
MIRT2157427	hsa-miR-4762-5p	CLIP-seq
MIRT2669287	hsa-miR-493	CLIP-seq
MIRT2669288	hsa-miR-518a-5p	CLIP-seq
MIRT2669289	hsa-miR-526b	CLIP-seq
MIRT2669290	hsa-miR-527	CLIP-seq
MIRT2669291	hsa-miR-548a-5p	CLIP-seq
MIRT2669292	hsa-miR-548ab	CLIP-seq
MIRT2669293	hsa-miR-548ak	CLIP-seq
MIRT2669294	hsa-miR-548b-5p	CLIP-seq
MIRT2669295	hsa-miR-548c-5p	CLIP-seq
MIRT2669296	hsa-miR-548d-5p	CLIP-seq
MIRT2669297	hsa-miR-548h	CLIP-seq
MIRT2669298	hsa-miR-548i	CLIP-seq
MIRT2669299	hsa-miR-548j	CLIP-seq
MIRT2669300	hsa-miR-548n	CLIP-seq
MIRT2669301	hsa-miR-548o	CLIP-seq
MIRT2669302	hsa-miR-548w	CLIP-seq
MIRT2669303	hsa-miR-548y	CLIP-seq
MIRT2669304	hsa-miR-559	CLIP-seq
MIRT2669305	hsa-miR-720	CLIP-seq
MIRT2669306	hsa-miR-92a	CLIP-seq
MIRT2669307	hsa-miR-92b	CLIP-seq
MIRT2669265	hsa-miR-1269	CLIP-seq
MIRT2669266	hsa-miR-1269b	CLIP-seq
MIRT2669268	hsa-miR-1976	CLIP-seq
MIRT2669270	hsa-miR-25	CLIP-seq
MIRT2669273	hsa-miR-32	CLIP-seq
MIRT2669274	hsa-miR-363	CLIP-seq
MIRT2376992	hsa-miR-3646	CLIP-seq
MIRT2669275	hsa-miR-367	CLIP-seq
MIRT1521375	hsa-miR-3690	CLIP-seq
MIRT2669277	hsa-miR-3974	CLIP-seq
MIRT1521382	hsa-miR-4254	CLIP-seq
MIRT2669278	hsa-miR-4259	CLIP-seq
MIRT1521385	hsa-miR-4307	CLIP-seq
MIRT2669281	hsa-miR-4529-3p	CLIP-seq
MIRT2669286	hsa-miR-4715-5p	CLIP-seq
MIRT2669287	hsa-miR-493	CLIP-seq
MIRT2669288	hsa-miR-518a-5p	CLIP-seq
MIRT2669290	hsa-miR-527	CLIP-seq
MIRT2669291	hsa-miR-548a-5p	CLIP-seq
MIRT2669292	hsa-miR-548ab	CLIP-seq
MIRT2669293	hsa-miR-548ak	CLIP-seq
MIRT2669294	hsa-miR-548b-5p	CLIP-seq
MIRT2669295	hsa-miR-548c-5p	CLIP-seq
MIRT2669296	hsa-miR-548d-5p	CLIP-seq
MIRT2669297	hsa-miR-548h	CLIP-seq
MIRT2669298	hsa-miR-548i	CLIP-seq
MIRT2669299	hsa-miR-548j	CLIP-seq
MIRT2669300	hsa-miR-548n	CLIP-seq
MIRT2669302	hsa-miR-548w	CLIP-seq
MIRT2669303	hsa-miR-548y	CLIP-seq
MIRT2669304	hsa-miR-559	CLIP-seq
MIRT2669306	hsa-miR-92a	CLIP-seq
MIRT2669307	hsa-miR-92b	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0003677	Function	DNA binding	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
616213	18410	ENSG00000188994

O60281

Protein name

Zinc finger protein 292

Protein function

May be involved in transcriptional regulation.

PDB

1X3C , 7N2D

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00096	zf-C2H2	807 → 831	Zinc finger, C2H2 type	Domain

Sequence

MADEEAEQERLSCGEGGCVAELQRLGERLQELELQLRESRVPAVEAATDYCQQLCQTLLE
YAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECENVALVLERLALSCVELLLCLPVE
LSDKQWEQFQTLVQVAHEKLMENGSCELHFLATLAQETGVWKNPVLCTILSQEPLDKDKV
NEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGIKGSFKQTYLVCLCTSSP
NGKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWS
KLQQRVEPSIQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLE
STENTEVKISICKTISCLLPDDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEE
NLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYE
KVVDYQEESKETSMNGLSGGVGANSGLLKDIGDEKQKKREIKQLRERGFISARFRNWQAY
MQYCVLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKETFVPHVTLHVKQSSKERL
AAMKPLRRLGRPPKITTTNENQKTNTVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDENDD
KDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDNEDAKRFLEMQSK
KVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLTHRKEHQVFRAK
CMFPKCGRIFSEAYLLYDHEAQHYNTYTCKFTGCGKVYRSQGELEKHLDDHSTPPEKVLP
PEAQLNSSGDSIQPSEVNQNTAENIEKERSMLPSENNIENSLLADRSDAWDKSKAESAVT
KQDQISASELRQANGPLSNGLENPATTPLLQSSEVAVSIKVSLNQGIEDNFGKQENSTVE
GSGEALVTDLHTPVEDTCNDLCHPGFQERKEQDCFNDAHVTQNSLVNSETLKIGDLTPQN
LERQVNNLMTFSVQNQAAFQNNLPTSKFECGDNVKTSSNLYNLPLKTLESIAFVPPQSDL
SNSLGTPSVPPKAPVQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKMQRKSKKGQ
KANNLNTPNNGKFVYFLPSPVNSSNPFFTSQTKANGNPACSAQLQHVSPPIFPAHLASVS
TPLLSSMESVINPNITSQDKNEQGGMLCSQMENLPSTALPAQMEDLTKTVLPLNIDSGSD
PFLPLPAESSSMSLFPSPADSGTNSVFSQLENNTNHYSSQIEGNTNSSFLKGGNGENAVF
PSQVNVANNFSSTNAQQSAPEKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRC
YRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQSNGQPSLLASMILSTNAVNLQQPQQS
TFNPEACFKDPSFLQLLAENRSPAFLPNTFPRSGVTNFNTSVSQEGSEIIKQALETAGIP
STFEGAEMLSHVSTGCVSDASQVNATVMPNPTVPPLLHTVCHPNTLLTNQNRTSNSKTSS
IEECSSLPVFPTNDLLLKTVENGLCSSSFPNSGGPSQNFTSNSSRVSVISGPQNTRSSHL
NKKGNSASKRRKKVAPPLIAPNASQNLVTSDLTTMGLIAKSVEIPTTNLHSNVIPTCEPQ
SLVENLTQKLNNVNNQLFMTDVKENFKTSLESHTVLAPLTLKTENGDSQMMALNSCTTSI
NSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGAGETSQNAQINYNIQLPSVNT
VQNNKLPDSSPFSSFISVMPTKSNIPQSEVSHKEDQIQEILEGLQKLKLENDLSTPASQC
VLINTSVTLTPTPVKSTADITVIQPVSEMINIQFNDKVNKPFVCQNQGCNYSAMTKDALF
KHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTTEEMV
KLKIKRPYGRKSQSENVPASRSTQVKKQLAMTEENKKESQPALELRAETQNTHSNVAVIP
EKQLVEKKSPDKTESSLQVITVTSEQCNTNALTNTQTKGRKIRRHKKEKEEKKRKKPVSQ
SLEFPTRYSPYRPYRCVHQGCFAAFTIQQNLILHYQAVHKSDLPAFSAEVEEESEAGKES
EETETKQTLKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTASVDVGKFPCDQ
LECKSSFTTYLNYVVHLEADHGIGLRASKTEEDGVYKCDCEGCDRIYATRSNLLRHIFNK
HNDKHKAHLIRPRRLTPGQENMSSKANQEKSKSKHRGTKHSRCGKEGIKMPKTKRKKKNN
LENKNAKIVQIEENKPYSLKRGKHVYSIKARNDALSECTSRFVTQYPCMIKGCTSVVTSE
SNIIRHYKCHKLSKAFTSQHRNLLIVFKRCCNSQVKETSEQEGAKNDVKDSDTCVSESND
NSRTTATVSQKEVEKNEKDEMDELTELFITKLINEDSTSVETQANTSSNVSNDFQEDNLC
QSERQKASNLKRVNKEKNVSQNKKRKVEKAEPASAAELSSVRKEEETAVAIQTIEEHPAS
FDWSSFKPMGFEVSFLKFLEESAVKQKKNTDKDHPNTGNKKGSHSNSRKNIDKTAVTSGN
HVCPCKESETFVQFANPSQLQCSDNVKIVLDKNLKDCTELVLKQLQEMKPTVSLKKLEVH
SNDPDMSVMKDISIGKATGRGQY

Sequence length

2723

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (11)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Autosomal dominant non-syndromic intellectual disability	Likely pathogenic	rs2482324124	RCV004577411	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual developmental disorder, autosomal dominant 64	Likely pathogenic; Pathogenic	rs2127862686, rs2127871142, rs2127864363, rs2127867444, rs2127870787, rs867732475, rs764995318, rs2127871067, rs2127872112, rs1775506324, rs1253246966, rs2482313661, rs2482327974, rs2482358615, rs2482346171 View all (18 more)	RCV003151863 RCV001775314 RCV001775419 RCV001806689 RCV001807990 View all (29 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Intellectual disability	Likely pathogenic; Pathogenic	rs764995318, rs1135401779, rs865909396, rs1775154516, rs1775236367, rs1301328139	RCV001815148 RCV000496170 RCV001260783 RCV001260789 RCV001260830 RCV001260794 View all (1 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Microcephaly	Likely pathogenic; Pathogenic	rs1775264625	RCV001290249	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Mild intellectual disability	Likely pathogenic; Pathogenic	rs1775264625	RCV001290249	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Motor delay	Likely pathogenic	rs2127862686	RCV001526603	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Neurodevelopmental delay	Pathogenic	rs2127859550	RCV002274393	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Neurodevelopmental disorder	Pathogenic; Likely pathogenic	rs2127867376, rs1135401779, rs1554208945, rs865909396, rs1775236367, rs1301328139, rs1772907934, rs1775120706, rs1775143865, rs1775161294, rs1775179321, rs1775194783, rs1775218146, rs1775264625, rs1775284293 View all (12 more)	RCV001374995 RCV001261701 RCV001261762 RCV001261693 RCV001261760 View all (22 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Short stature	Likely pathogenic; Pathogenic	rs1775264625	RCV001290249	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
ZNF292-related disorder	Likely pathogenic; Pathogenic	rs764995318, rs2482353470, rs1775229041, rs1775161294	RCV004741084 RCV003402532 RCV003919462 RCV003416137	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
ZNF292-related neurodevelopmental condition	Likely pathogenic	rs1554208945	RCV000626040	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (13)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Arterial calcification, generalized, of infancy, 1	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISTIC DISORDER	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Complex neurodevelopmental disorder	Uncertain significance; Conflicting classifications of pathogenicity	ClinVar ClinGen, GenCC	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Gastric cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet, Orphanet Disgenet, Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (40)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acrodermatitis enteropathica	Acrodermatitis Enteropathica	BEFREE	9498326		★★★★★ ★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	21116278	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Alzheimer`s Disease	Alzheimer disease	GWASCAT_DG	21116278		★★★★★ ★☆☆☆☆ Found in Text Mining only
Alzheimer`s Disease	Alzheimer disease	GWASDB_DG	21116278		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	25880754	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Attention Deficit and Disruptive Behavior Disorders	Attention deficit hyperactivity disorder	Pubtator	30564305	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	GENOMICS_ENGLAND_DG	29904178		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	27824329	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	27824329, 31723249		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	Pubtator	27824329, 29904178, 30564305	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic Disorder	Autism	GENOMICS_ENGLAND_DG	29904178		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	33201835	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	33336730	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Abnormalities	Cardiovascular Abnormalities	GENOMICS_ENGLAND_DG	29904178		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebral Palsy	Cerebral palsy	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	CTD_human_DG	25559195		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	27150435		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	CTD_human_DG	25559195		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Congenital Epicanthus	Congenital Epicanthus	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital pectus carinatum	Congenital Pectus Carinatum	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	29904178, 31723249	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Epileptic encephalopathy	Epileptic encephalopathy	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	GENOMICS_ENGLAND_DG	29904178		★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Intellectual Disability	Mental retardation	BEFREE	31723249		★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Malignant neoplasm of prostate	Prostate cancer	CTD_human_DG	29610475, 29662167		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	25559195		★★★★★ ★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	GENOMICS_ENGLAND_DG	29904178		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Micrognathism	Micrognathism	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopia	Myopia	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27150435		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodevelopmental Disorders	Neurodevelopmental Disorders	CTD_human_DG	28191889		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neurodevelopmental Disorders	Neurodevelopmental Disorders	BEFREE	29158550, 31723249		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Orofaciodigital Syndromes	Orofaciodigital syndrome	Pubtator	19587378	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pervasive Development Disorder	Autism spectrum disorder	BEFREE	31723249		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	CTD_human_DG	29610475, 29662167		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	37279148	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	25880754		★★★★★ ★☆☆☆☆ Found in Text Mining only
Salaam Seizures	Salaam Seizures	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Scoliosis, unspecified	Scoliosis	CLINVAR_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF292 (zinc finger protein 292)