Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	22911
Gene name	WD repeat domain 47
Gene symbol	WDR47
Synonyms (NCBI Gene)	-
Chromosome	1
Chromosome location	1p13.3

112

Show/Hide all (112)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024637	hsa-miR-215-5p	Microarray	19074876
MIRT026954	hsa-miR-192-5p	Microarray	19074876
MIRT1490768	hsa-miR-203	CLIP-seq
MIRT1490769	hsa-miR-217	CLIP-seq
MIRT1490770	hsa-miR-3140-3p	CLIP-seq
MIRT1490771	hsa-miR-3163	CLIP-seq
MIRT1490772	hsa-miR-3692	CLIP-seq
MIRT1490773	hsa-miR-4436b-5p	CLIP-seq
MIRT1490774	hsa-miR-4668-3p	CLIP-seq
MIRT1490775	hsa-miR-548c-3p	CLIP-seq
MIRT1490776	hsa-miR-576-5p	CLIP-seq
MIRT1490777	hsa-miR-935	CLIP-seq
MIRT1490778	hsa-miR-15a	CLIP-seq
MIRT1490779	hsa-miR-15b	CLIP-seq
MIRT1490780	hsa-miR-16	CLIP-seq
MIRT1490781	hsa-miR-195	CLIP-seq
MIRT1490782	hsa-miR-3173-3p	CLIP-seq
MIRT1490783	hsa-miR-338-5p	CLIP-seq
MIRT1490784	hsa-miR-3670	CLIP-seq
MIRT1490785	hsa-miR-3688-3p	CLIP-seq
MIRT1490786	hsa-miR-369-3p	CLIP-seq
MIRT1490787	hsa-miR-374c	CLIP-seq
MIRT1490788	hsa-miR-3941	CLIP-seq
MIRT1490789	hsa-miR-424	CLIP-seq
MIRT1490790	hsa-miR-4256	CLIP-seq
MIRT1490791	hsa-miR-4428	CLIP-seq
MIRT1490792	hsa-miR-4477b	CLIP-seq
MIRT1490793	hsa-miR-450b-3p	CLIP-seq
MIRT1490794	hsa-miR-4528	CLIP-seq
MIRT1490795	hsa-miR-466	CLIP-seq
MIRT1490796	hsa-miR-4666-3p	CLIP-seq
MIRT1490797	hsa-miR-4672	CLIP-seq
MIRT1490798	hsa-miR-4690-5p	CLIP-seq
MIRT1490799	hsa-miR-4699-3p	CLIP-seq
MIRT1490800	hsa-miR-4713-3p	CLIP-seq
MIRT1490801	hsa-miR-4717-3p	CLIP-seq
MIRT1490802	hsa-miR-4731-3p	CLIP-seq
MIRT1490803	hsa-miR-4778-5p	CLIP-seq
MIRT1490804	hsa-miR-4801	CLIP-seq
MIRT1490805	hsa-miR-4802-3p	CLIP-seq
MIRT1490806	hsa-miR-497	CLIP-seq
MIRT1490807	hsa-miR-513a-3p	CLIP-seq
MIRT1490808	hsa-miR-544	CLIP-seq
MIRT1490809	hsa-miR-638	CLIP-seq
MIRT1490810	hsa-miR-655	CLIP-seq
MIRT1490811	hsa-miR-7	CLIP-seq
MIRT1490812	hsa-miR-769-3p	CLIP-seq
MIRT2147927	hsa-miR-1343	CLIP-seq
MIRT2147928	hsa-miR-3074-5p	CLIP-seq
MIRT2147929	hsa-miR-3117-5p	CLIP-seq
MIRT2147930	hsa-miR-3124-3p	CLIP-seq
MIRT2147931	hsa-miR-3690	CLIP-seq
MIRT2147932	hsa-miR-3936	CLIP-seq
MIRT2147933	hsa-miR-4254	CLIP-seq
MIRT2147934	hsa-miR-4638-3p	CLIP-seq
MIRT2147935	hsa-miR-4757-5p	CLIP-seq
MIRT2147936	hsa-miR-517a	CLIP-seq
MIRT2147937	hsa-miR-517c	CLIP-seq
MIRT2396950	hsa-miR-4499	CLIP-seq
MIRT2463426	hsa-miR-4709-3p	CLIP-seq
MIRT2463426	hsa-miR-4709-3p	CLIP-seq
MIRT2661999	hsa-miR-1253	CLIP-seq
MIRT1490768	hsa-miR-203	CLIP-seq
MIRT1490769	hsa-miR-217	CLIP-seq
MIRT1490771	hsa-miR-3163	CLIP-seq
MIRT1490783	hsa-miR-338-5p	CLIP-seq
MIRT2662000	hsa-miR-3591-3p	CLIP-seq
MIRT1490785	hsa-miR-3688-3p	CLIP-seq
MIRT1490786	hsa-miR-369-3p	CLIP-seq
MIRT1490787	hsa-miR-374c	CLIP-seq
MIRT2662001	hsa-miR-425	CLIP-seq
MIRT1490790	hsa-miR-4256	CLIP-seq
MIRT1490793	hsa-miR-450b-3p	CLIP-seq
MIRT2662002	hsa-miR-4539	CLIP-seq
MIRT2662003	hsa-miR-4646-5p	CLIP-seq
MIRT2662004	hsa-miR-4654	CLIP-seq
MIRT1490796	hsa-miR-4666-3p	CLIP-seq
MIRT1490800	hsa-miR-4713-3p	CLIP-seq
MIRT2662005	hsa-miR-4769-5p	CLIP-seq
MIRT1490805	hsa-miR-4802-3p	CLIP-seq
MIRT2662006	hsa-miR-494	CLIP-seq
MIRT2662007	hsa-miR-548a-5p	CLIP-seq
MIRT2662008	hsa-miR-548ab	CLIP-seq
MIRT2662009	hsa-miR-548ak	CLIP-seq
MIRT2662010	hsa-miR-548b-5p	CLIP-seq
MIRT2662011	hsa-miR-548c-5p	CLIP-seq
MIRT2662012	hsa-miR-548d-5p	CLIP-seq
MIRT2662013	hsa-miR-548h	CLIP-seq
MIRT2662014	hsa-miR-548i	CLIP-seq
MIRT2662015	hsa-miR-548j	CLIP-seq
MIRT2662016	hsa-miR-548n	CLIP-seq
MIRT2662017	hsa-miR-548p	CLIP-seq
MIRT2662018	hsa-miR-548w	CLIP-seq
MIRT2662019	hsa-miR-548y	CLIP-seq
MIRT2662020	hsa-miR-559	CLIP-seq
MIRT1490809	hsa-miR-638	CLIP-seq
MIRT1490810	hsa-miR-655	CLIP-seq
MIRT2662021	hsa-miR-656	CLIP-seq
MIRT1490812	hsa-miR-769-3p	CLIP-seq
MIRT2662000	hsa-miR-3591-3p	CLIP-seq
MIRT1490786	hsa-miR-369-3p	CLIP-seq
MIRT1490787	hsa-miR-374c	CLIP-seq
MIRT2147932	hsa-miR-3936	CLIP-seq
MIRT2662001	hsa-miR-425	CLIP-seq
MIRT2662004	hsa-miR-4654	CLIP-seq
MIRT2147935	hsa-miR-4757-5p	CLIP-seq
MIRT2662005	hsa-miR-4769-5p	CLIP-seq
MIRT1490805	hsa-miR-4802-3p	CLIP-seq
MIRT2662006	hsa-miR-494	CLIP-seq
MIRT2147936	hsa-miR-517a	CLIP-seq
MIRT2147937	hsa-miR-517c	CLIP-seq
MIRT1490810	hsa-miR-655	CLIP-seq

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000226	Process	Microtubule cytoskeleton organization	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 33961781
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0006914	Process	Autophagy	IEA
GO:0007026	Process	Negative regulation of microtubule depolymerization	IEA
GO:0007420	Process	Brain development	IEA
GO:0007626	Process	Locomotory behavior	IEA
GO:0008344	Process	Adult locomotory behavior	IEA
GO:0021801	Process	Cerebral cortex radial glia-guided migration	IEA
GO:0021960	Process	Anterior commissure morphogenesis	IEA
GO:0021987	Process	Cerebral cortex development	IEA
GO:0022038	Process	Corpus callosum development	IEA
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0030426	Component	Growth cone	IEA
GO:0031175	Process	Neuron projection development	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0043025	Component	Neuronal cell body	IEA
GO:0061351	Process	Neural precursor cell proliferation	IEA
GO:0061744	Process	Motor behavior	IEA
GO:0097150	Process	Neuronal stem cell population maintenance	IEA
GO:0120168	Process	Detection of hot stimulus involved in thermoception	IEA

MIM	HGNC	e!Ensembl
615734	29141	ENSG00000085433

O94967

Protein name

WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF17814	LisH_TPL	12 → 40		Domain
PF00400	WD40	649 → 687	WD domain, G-beta repeat	Repeat
PF00400	WD40	745 → 782	WD domain, G-beta repeat	Repeat
PF00400	WD40	787 → 828	WD domain, G-beta repeat	Repeat
PF00400	WD40	832 → 870	WD domain, G-beta repeat	Repeat

Sequence

MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQ
WDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHLEFTMQEAVQC
LHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADR
KLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDL
DLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMR
RPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSL
MLENTECHSIYEESPERDTPVDAQRPIGSEILGQSSVSEKEPANGAQNPGPAKQEKNELR
DSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGPDQQQNLTEQFLNRSI
QKLGELNIGMDGLGNEVSALNQQCNGSKGNGSNGSSVTSFTTPPQDSSQRLTHDASNIHT
STPRNPGSTNHIPFLEESPCGSQISSEHSVIKPPLGDSPGSLSRSKGEEDDKSKKQFVCI
NILEDTQAVRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHH
KGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGP
ESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRF
WDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHP
HSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQD
LSFLSSSADRTVTLWTYNG

Sequence length

919

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Cardiovascular Abnormalities	Cardiovascular abnormalities	Pubtator	35474353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Defects Congenital	Congenital heart defect	Pubtator	35474353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heterotaxy Syndrome	Heterotaxy syndrome	Pubtator	35474353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lissencephaly	Lissencephaly	BEFREE	29078390		★★★★★ ★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	BEFREE	29078390		★★★★★ ★☆☆☆☆ Found in Text Mining only
Situs Inversus	Situs inversus	Pubtator	35474353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

WDR47 (WD repeat domain 47)