TRAK1 (trafficking kinesin protein 1)

Gene

• Entrez ID: 22906
• Gene name: Trafficking kinesin protein 1
• Gene symbol: TRAK1
• Synonyms (NCBI Gene): DEE68, EIEE68, MILT1, OIP106
• Chromosome: 3
• Chromosome location: 3p22.1

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1553608726	AG>-	Likely-pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1559390743	->C	Pathogenic-likely-pathogenic	Frameshift variant, genic downstream transcript variant, non coding transcript variant, coding sequence variant
rs1559877920	A>C,G	Pathogenic	Splice acceptor variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020781	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT048852	hsa-miR-93-5p	CLASH	23622248
MIRT042880	hsa-miR-324-3p	CLASH	23622248
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT627359	hsa-miR-711	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	27418678
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	27418678
MIRT614702	hsa-miR-16-5p	HITS-CLIP	27418678
MIRT614701	hsa-miR-195-5p	HITS-CLIP	27418678
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	27418678
MIRT614698	hsa-miR-424-5p	HITS-CLIP	27418678
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	27418678
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	27418678
MIRT614699	hsa-miR-497-5p	HITS-CLIP	27418678
MIRT614695	hsa-miR-503-5p	HITS-CLIP	27418678
MIRT614694	hsa-miR-646	HITS-CLIP	27418678
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	27418678
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT627359	hsa-miR-711	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT614702	hsa-miR-16-5p	HITS-CLIP	23824327
MIRT614701	hsa-miR-195-5p	HITS-CLIP	23824327
MIRT614700	hsa-miR-6838-5p	HITS-CLIP	23824327
MIRT614699	hsa-miR-497-5p	HITS-CLIP	23824327
MIRT614698	hsa-miR-424-5p	HITS-CLIP	23824327
MIRT614697	hsa-miR-15a-5p	HITS-CLIP	23824327
MIRT614696	hsa-miR-15b-5p	HITS-CLIP	23824327
MIRT614695	hsa-miR-503-5p	HITS-CLIP	23824327
MIRT614694	hsa-miR-646	HITS-CLIP	23824327
MIRT614693	hsa-miR-4524a-5p	HITS-CLIP	23824327
MIRT614692	hsa-miR-4524b-5p	HITS-CLIP	23824327
MIRT614691	hsa-miR-374b-3p	HITS-CLIP	23824327
MIRT1451317	hsa-miR-103a	CLIP-seq
MIRT1451318	hsa-miR-107	CLIP-seq
MIRT1451319	hsa-miR-1197	CLIP-seq
MIRT1451320	hsa-miR-1324	CLIP-seq
MIRT1451321	hsa-miR-146a	CLIP-seq
MIRT1451322	hsa-miR-146b-5p	CLIP-seq
MIRT1451323	hsa-miR-181a	CLIP-seq
MIRT1451324	hsa-miR-181b	CLIP-seq
MIRT1451325	hsa-miR-181c	CLIP-seq
MIRT1451326	hsa-miR-181d	CLIP-seq
MIRT1451327	hsa-miR-214	CLIP-seq
MIRT1451328	hsa-miR-3160-3p	CLIP-seq
MIRT1451329	hsa-miR-3184	CLIP-seq
MIRT1451330	hsa-miR-3619-5p	CLIP-seq
MIRT1451331	hsa-miR-3659	CLIP-seq
MIRT1451332	hsa-miR-377	CLIP-seq
MIRT1451333	hsa-miR-423-5p	CLIP-seq
MIRT1451334	hsa-miR-4251	CLIP-seq
MIRT1451335	hsa-miR-4262	CLIP-seq
MIRT1451336	hsa-miR-4270	CLIP-seq
MIRT1451337	hsa-miR-4441	CLIP-seq
MIRT1451338	hsa-miR-4658	CLIP-seq
MIRT1451339	hsa-miR-4753-3p	CLIP-seq
MIRT1451340	hsa-miR-574-5p	CLIP-seq
MIRT1451341	hsa-miR-589	CLIP-seq
MIRT1451342	hsa-miR-761	CLIP-seq
MIRT1451343	hsa-miR-1246	CLIP-seq
MIRT1451344	hsa-miR-223	CLIP-seq
MIRT1451345	hsa-miR-3154	CLIP-seq
MIRT1451346	hsa-miR-3185	CLIP-seq
MIRT1451347	hsa-miR-3192	CLIP-seq
MIRT1451348	hsa-miR-338-5p	CLIP-seq
MIRT1451349	hsa-miR-3689a-3p	CLIP-seq
MIRT1451350	hsa-miR-3689c	CLIP-seq
MIRT1451351	hsa-miR-4302	CLIP-seq
MIRT1451352	hsa-miR-4305	CLIP-seq
MIRT1451353	hsa-miR-4320	CLIP-seq
MIRT1451354	hsa-miR-4492	CLIP-seq
MIRT1451355	hsa-miR-4498	CLIP-seq
MIRT1451356	hsa-miR-4505	CLIP-seq
MIRT1451357	hsa-miR-451b	CLIP-seq
MIRT1451358	hsa-miR-4666-3p	CLIP-seq
MIRT1451359	hsa-miR-4697-3p	CLIP-seq
MIRT1451360	hsa-miR-4699-3p	CLIP-seq
MIRT1451361	hsa-miR-4728-5p	CLIP-seq
MIRT1451362	hsa-miR-4802-3p	CLIP-seq
MIRT1451363	hsa-miR-490-5p	CLIP-seq
MIRT1451364	hsa-miR-548b-3p	CLIP-seq
MIRT1451365	hsa-miR-762	CLIP-seq
MIRT2134927	hsa-miR-3074-5p	CLIP-seq
MIRT2134928	hsa-miR-30a	CLIP-seq
MIRT2134929	hsa-miR-30b	CLIP-seq
MIRT2134930	hsa-miR-30c	CLIP-seq
MIRT2134931	hsa-miR-30d	CLIP-seq
MIRT2134932	hsa-miR-30e	CLIP-seq
MIRT2134933	hsa-miR-3124-3p	CLIP-seq
MIRT1451345	hsa-miR-3154	CLIP-seq
MIRT1451346	hsa-miR-3185	CLIP-seq
MIRT2356152	hsa-miR-15a	CLIP-seq
MIRT2356153	hsa-miR-15b	CLIP-seq
MIRT2356154	hsa-miR-16	CLIP-seq
MIRT2356155	hsa-miR-195	CLIP-seq
MIRT2134933	hsa-miR-3124-3p	CLIP-seq
MIRT1451345	hsa-miR-3154	CLIP-seq
MIRT2356156	hsa-miR-3157-5p	CLIP-seq
MIRT1451346	hsa-miR-3185	CLIP-seq
MIRT2356157	hsa-miR-424	CLIP-seq
MIRT2356158	hsa-miR-4524	CLIP-seq
MIRT2356159	hsa-miR-4691-3p	CLIP-seq
MIRT2356160	hsa-miR-497	CLIP-seq
MIRT2356161	hsa-miR-503	CLIP-seq
MIRT2396274	hsa-miR-1289	CLIP-seq
MIRT2396275	hsa-miR-1293	CLIP-seq
MIRT2356156	hsa-miR-3157-5p	CLIP-seq
MIRT2396276	hsa-miR-3198	CLIP-seq
MIRT2396277	hsa-miR-4294	CLIP-seq
MIRT2396278	hsa-miR-4309	CLIP-seq
MIRT2396279	hsa-miR-4483	CLIP-seq
MIRT2356159	hsa-miR-4691-3p	CLIP-seq
MIRT2649659	hsa-miR-1252	CLIP-seq
MIRT2649660	hsa-miR-1256	CLIP-seq
MIRT2649661	hsa-miR-1272	CLIP-seq
MIRT2649662	hsa-miR-1279	CLIP-seq
MIRT2649663	hsa-miR-134	CLIP-seq
MIRT2649664	hsa-miR-1910	CLIP-seq
MIRT2649665	hsa-miR-2053	CLIP-seq
MIRT2649666	hsa-miR-2277-3p	CLIP-seq
MIRT2649667	hsa-miR-299-3p	CLIP-seq
MIRT2649668	hsa-miR-3065-3p	CLIP-seq
MIRT2649669	hsa-miR-3118	CLIP-seq
MIRT2649670	hsa-miR-3128	CLIP-seq
MIRT2649671	hsa-miR-3163	CLIP-seq
MIRT2649672	hsa-miR-3164	CLIP-seq
MIRT2649673	hsa-miR-3166	CLIP-seq
MIRT2649674	hsa-miR-3194-5p	CLIP-seq
MIRT2649675	hsa-miR-3202	CLIP-seq
MIRT2649676	hsa-miR-323b-5p	CLIP-seq
MIRT2649677	hsa-miR-3620	CLIP-seq
MIRT2649678	hsa-miR-362-5p	CLIP-seq
MIRT2649679	hsa-miR-3662	CLIP-seq
MIRT2649680	hsa-miR-3921	CLIP-seq
MIRT2649681	hsa-miR-3942-3p	CLIP-seq
MIRT2649682	hsa-miR-3945	CLIP-seq
MIRT2649683	hsa-miR-4253	CLIP-seq
MIRT2649684	hsa-miR-4265	CLIP-seq
MIRT2649685	hsa-miR-4296	CLIP-seq
MIRT2649686	hsa-miR-431	CLIP-seq
MIRT2649687	hsa-miR-4322	CLIP-seq
MIRT2649688	hsa-miR-4417	CLIP-seq
MIRT2649689	hsa-miR-4422	CLIP-seq
MIRT2649690	hsa-miR-4427	CLIP-seq
MIRT2649691	hsa-miR-4435	CLIP-seq
MIRT2649692	hsa-miR-4446-5p	CLIP-seq
MIRT2649693	hsa-miR-4481	CLIP-seq
MIRT2649694	hsa-miR-4533	CLIP-seq
MIRT2649695	hsa-miR-455-3p	CLIP-seq
MIRT2649696	hsa-miR-4653-5p	CLIP-seq
MIRT2649697	hsa-miR-4666-5p	CLIP-seq
MIRT2649698	hsa-miR-4680-3p	CLIP-seq
MIRT2649699	hsa-miR-4711-3p	CLIP-seq
MIRT2649700	hsa-miR-4720-5p	CLIP-seq
MIRT2649701	hsa-miR-4738-3p	CLIP-seq
MIRT2649702	hsa-miR-4745-5p	CLIP-seq
MIRT2649703	hsa-miR-4755-5p	CLIP-seq
MIRT2649704	hsa-miR-4758-5p	CLIP-seq
MIRT2649705	hsa-miR-4768-5p	CLIP-seq
MIRT2649706	hsa-miR-4790-3p	CLIP-seq
MIRT2649707	hsa-miR-4799-3p	CLIP-seq
MIRT1451362	hsa-miR-4802-3p	CLIP-seq
MIRT2649708	hsa-miR-494	CLIP-seq
MIRT2649709	hsa-miR-500b	CLIP-seq
MIRT2649710	hsa-miR-501-5p	CLIP-seq
MIRT2649711	hsa-miR-518a-3p	CLIP-seq
MIRT2649712	hsa-miR-518b	CLIP-seq
MIRT2649713	hsa-miR-518c	CLIP-seq
MIRT2649714	hsa-miR-518d-3p	CLIP-seq
MIRT2649715	hsa-miR-518e	CLIP-seq
MIRT2649716	hsa-miR-518f	CLIP-seq
MIRT2649717	hsa-miR-522	CLIP-seq
MIRT2649718	hsa-miR-542-3p	CLIP-seq
MIRT2649719	hsa-miR-548al	CLIP-seq
MIRT2649720	hsa-miR-548m	CLIP-seq
MIRT2649721	hsa-miR-604	CLIP-seq
MIRT2649722	hsa-miR-635	CLIP-seq
MIRT2649723	hsa-miR-642b	CLIP-seq
MIRT2649724	hsa-miR-647	CLIP-seq
MIRT2649725	hsa-miR-659	CLIP-seq
MIRT2649726	hsa-miR-758	CLIP-seq
MIRT2649727	hsa-miR-942	CLIP-seq
MIRT2694056	hsa-miR-1227	CLIP-seq
MIRT2649659	hsa-miR-1252	CLIP-seq
MIRT2649660	hsa-miR-1256	CLIP-seq
MIRT2649661	hsa-miR-1272	CLIP-seq
MIRT2649662	hsa-miR-1279	CLIP-seq
MIRT2649664	hsa-miR-1910	CLIP-seq
MIRT2694057	hsa-miR-1912	CLIP-seq
MIRT2649665	hsa-miR-2053	CLIP-seq
MIRT2649666	hsa-miR-2277-3p	CLIP-seq
MIRT2694058	hsa-miR-2467-5p	CLIP-seq
MIRT2649667	hsa-miR-299-3p	CLIP-seq
MIRT2649668	hsa-miR-3065-3p	CLIP-seq
MIRT2694059	hsa-miR-3121-5p	CLIP-seq
MIRT2649670	hsa-miR-3128	CLIP-seq
MIRT2694060	hsa-miR-3135b	CLIP-seq
MIRT2694061	hsa-miR-3138	CLIP-seq
MIRT2694062	hsa-miR-3152-3p	CLIP-seq
MIRT2694063	hsa-miR-3160-5p	CLIP-seq
MIRT2649671	hsa-miR-3163	CLIP-seq
MIRT2694064	hsa-miR-3165	CLIP-seq
MIRT2649673	hsa-miR-3166	CLIP-seq
MIRT2694065	hsa-miR-3188	CLIP-seq
MIRT2694066	hsa-miR-3189-3p	CLIP-seq
MIRT2649674	hsa-miR-3194-5p	CLIP-seq
MIRT2649675	hsa-miR-3202	CLIP-seq
MIRT2649677	hsa-miR-3620	CLIP-seq
MIRT2649678	hsa-miR-362-5p	CLIP-seq
MIRT2694067	hsa-miR-3648	CLIP-seq
MIRT2694068	hsa-miR-3650	CLIP-seq
MIRT2649679	hsa-miR-3662	CLIP-seq
MIRT2694069	hsa-miR-3669	CLIP-seq
MIRT2694070	hsa-miR-371-5p	CLIP-seq
MIRT2694071	hsa-miR-371b-5p	CLIP-seq
MIRT2649680	hsa-miR-3921	CLIP-seq
MIRT2649681	hsa-miR-3942-3p	CLIP-seq
MIRT2649682	hsa-miR-3945	CLIP-seq
MIRT2694072	hsa-miR-3973	CLIP-seq
MIRT2694073	hsa-miR-3975	CLIP-seq
MIRT2694074	hsa-miR-409-5p	CLIP-seq
MIRT2649683	hsa-miR-4253	CLIP-seq
MIRT2649684	hsa-miR-4265	CLIP-seq
MIRT2694075	hsa-miR-4278	CLIP-seq
MIRT2649685	hsa-miR-4296	CLIP-seq
MIRT2649686	hsa-miR-431	CLIP-seq
MIRT2649687	hsa-miR-4322	CLIP-seq
MIRT2694076	hsa-miR-4326	CLIP-seq
MIRT2649688	hsa-miR-4417	CLIP-seq
MIRT2649689	hsa-miR-4422	CLIP-seq
MIRT2649690	hsa-miR-4427	CLIP-seq
MIRT2649691	hsa-miR-4435	CLIP-seq
MIRT2649692	hsa-miR-4446-5p	CLIP-seq
MIRT2649693	hsa-miR-4481	CLIP-seq
MIRT2649694	hsa-miR-4533	CLIP-seq
MIRT2649695	hsa-miR-455-3p	CLIP-seq
MIRT2649696	hsa-miR-4653-5p	CLIP-seq
MIRT2649697	hsa-miR-4666-5p	CLIP-seq
MIRT2649698	hsa-miR-4680-3p	CLIP-seq
MIRT2694077	hsa-miR-4688	CLIP-seq
MIRT2649699	hsa-miR-4711-3p	CLIP-seq
MIRT2649700	hsa-miR-4720-5p	CLIP-seq
MIRT2649701	hsa-miR-4738-3p	CLIP-seq
MIRT2649702	hsa-miR-4745-5p	CLIP-seq
MIRT2649703	hsa-miR-4755-5p	CLIP-seq
MIRT2649704	hsa-miR-4758-5p	CLIP-seq
MIRT2649705	hsa-miR-4768-5p	CLIP-seq
MIRT2649706	hsa-miR-4790-3p	CLIP-seq
MIRT2649707	hsa-miR-4799-3p	CLIP-seq
MIRT1451362	hsa-miR-4802-3p	CLIP-seq
MIRT2694078	hsa-miR-485-5p	CLIP-seq
MIRT2649708	hsa-miR-494	CLIP-seq
MIRT2649709	hsa-miR-500b	CLIP-seq
MIRT2649710	hsa-miR-501-5p	CLIP-seq
MIRT2694079	hsa-miR-513c	CLIP-seq
MIRT2694080	hsa-miR-514b-5p	CLIP-seq
MIRT2649711	hsa-miR-518a-3p	CLIP-seq
MIRT2649712	hsa-miR-518b	CLIP-seq
MIRT2649713	hsa-miR-518c	CLIP-seq
MIRT2649714	hsa-miR-518d-3p	CLIP-seq
MIRT2649715	hsa-miR-518e	CLIP-seq
MIRT2649716	hsa-miR-518f	CLIP-seq
MIRT2694081	hsa-miR-520g	CLIP-seq
MIRT2694082	hsa-miR-520h	CLIP-seq
MIRT2649717	hsa-miR-522	CLIP-seq
MIRT2649718	hsa-miR-542-3p	CLIP-seq
MIRT2694083	hsa-miR-548a-3p	CLIP-seq
MIRT2649719	hsa-miR-548al	CLIP-seq
MIRT2694084	hsa-miR-548e	CLIP-seq
MIRT2694085	hsa-miR-548f	CLIP-seq
MIRT2694086	hsa-miR-548l	CLIP-seq
MIRT2649720	hsa-miR-548m	CLIP-seq
MIRT2694087	hsa-miR-548n	CLIP-seq
MIRT2694088	hsa-miR-548t	CLIP-seq
MIRT2694089	hsa-miR-561	CLIP-seq
MIRT2694090	hsa-miR-576-3p	CLIP-seq
MIRT2649721	hsa-miR-604	CLIP-seq
MIRT2649722	hsa-miR-635	CLIP-seq
MIRT2649723	hsa-miR-642b	CLIP-seq
MIRT2649724	hsa-miR-647	CLIP-seq
MIRT2649727	hsa-miR-942	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	15644324, 16630562, 18675823, 19135897, 19528298, 24161670, 24995978, 27705803, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IDA	19528298
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	15644324, 18675823, 19528298
GO:0005739	Component	Mitochondrion	IEA
GO:0005768	Component	Endosome	IEA
GO:0005769	Component	Early endosome	IDA	18675823
GO:0005769	Component	Early endosome	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005938	Component	Cell cortex	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	ISS
GO:0006493	Process	Protein O-linked glycosylation	ISS
GO:0006605	Process	Protein targeting	IBA
GO:0006605	Process	Protein targeting	ISS
GO:0008333	Process	Endosome to lysosome transport	IBA
GO:0008333	Process	Endosome to lysosome transport	IDA	18675823
GO:0016020	Component	Membrane	IEA
GO:0017022	Function	Myosin binding	IBA
GO:0019896	Process	Axonal transport of mitochondrion	IEA
GO:0022008	Process	Neurogenesis	IBA
GO:0030425	Component	Dendrite	IBA
GO:0030425	Component	Dendrite	IEA
GO:0030911	Function	TPR domain binding	IEA
GO:0031410	Component	Cytoplasmic vesicle	IBA
GO:0031966	Component	Mitochondrial membrane	IEA
GO:0044295	Component	Axonal growth cone	IEA
GO:0047496	Process	Vesicle transport along microtubule	IBA
GO:0048311	Process	Mitochondrion distribution	IBA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048813	Process	Dendrite morphogenesis	IEA
GO:0050772	Process	Positive regulation of axonogenesis	IEA
GO:0050811	Function	GABA receptor binding	IBA
GO:1904115	Component	Axon cytoplasm	IEA

Other IDs

• MIM: 608112
• HGNC: 29947
• e!Ensembl: ENSG00000182606

Protein

• UniProt ID: Q9UPV9
• Protein name: Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
• Protein function: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors (PubMed:18675823). Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motili
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04849	HAP1_N	48 → 353	HAP1 N-terminal conserved region	Family
  PF12448	Milton	414 → 583	Kinesin associated protein	Family

• Tissue specificity: TISSUE SPECIFICITY: High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined. {ECO:0000269|PubMed:18986759}.
• Sequence:

  MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
  IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
  EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
  AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
  YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
  CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
  RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
  SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
  SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
  TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
  LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
  CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL
  AESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPS
  TPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSN
  LNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPT
  VTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR

• Sequence length: 953

Pathways

Reactome:

Signaling by BRAF and RAF fusions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Developmental and epileptic encephalopathy, 68	Pathogenic; Likely pathogenic	rs1559877920, rs1559390743	RCV000722133 RCV000722134 RCV000722135	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Uterine corpus endometrial carcinoma	Pathogenic	rs2149140090	RCV005922407	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Uncertain significance; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 68	—	Disgenet, HPO Disgenet, HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEVELOPMENTAL DISABILITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial pancreatic carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEART FAILURE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC EARLY-ONSET EPILEPTIC ENCEPHALOPATHY	—	Disgenet, Orphanet Disgenet, Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SARCOIDOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TRAK1-related disorder	Likely benign; Benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UNDETERMINED EARLY-ONSET EPILEPTIC ENCEPHALOPATHY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenoma of large intestine	Colorectal adenoma	BEFREE	21999571		★☆☆☆☆ Found in Text Mining only
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	HPO_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorder	Autism	Pubtator	35205252	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic Disorder	Autism	HPO_DG			★☆☆☆☆ Found in Text Mining only
Blepharoptosis	Ptosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Brain Diseases	Brain disease	Pubtator	28364549	Associate	★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain neoplasms	Pubtator	37399073	Associate	★☆☆☆☆ Found in Text Mining only
Cerebral atrophy	Cerebral Atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Cerebral cortical atrophy	Cerebral cortical atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	21999571	Associate	★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	28364549	Associate	★☆☆☆☆ Found in Text Mining only
Developmental regression	Developmental regression	HPO_DG			★☆☆☆☆ Found in Text Mining only
Dwarfism	Dwarfism	HPO_DG			★☆☆☆☆ Found in Text Mining only
Dyskinetic syndrome	Dyskinetic Syndrome	HPO_DG			★☆☆☆☆ Found in Text Mining only
Encephalopathies	Epileptic encephalopathy	BEFREE	28364549		★☆☆☆☆ Found in Text Mining only
Encephalopathies	Epileptic encephalopathy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Epilepsy Absence	Absence epilepsy	Pubtator	19837565	Associate	★☆☆☆☆ Found in Text Mining only
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68	Epileptic encephalopathy	GENOMICS_ENGLAND_DG	28364549		★☆☆☆☆ Found in Text Mining only
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68	Epileptic encephalopathy	UNIPROT_DG	28364549, 28940097, 29846532		★☆☆☆☆ Found in Text Mining only
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68	Epileptic encephalopathy	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Gastroesophageal reflux disease	Gastroesophageal Reflux Disease	HPO_DG			★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	37399073	Associate	★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypodontia	Hypodontia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	HPO_DG			★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	21999571, 28924745		★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	HPO_DG			★☆☆☆☆ Found in Text Mining only
Movement Disorders	Movement Disorders	CLINVAR_DG	12435728, 15644324, 16380713, 18675823, 23395375, 23603762, 24161670, 28300646, 28364549		★☆☆☆☆ Found in Text Mining only
Mucinous Adenocarcinoma	Mucinous Adenocarcinoma	LHGDN	18986759		★☆☆☆☆ Found in Text Mining only
nervous system disorder	Nervous System Disorder	BEFREE	18675823		★☆☆☆☆ Found in Text Mining only
Neurodevelopmental Disorders	Neurodevelopmental Disorders	BEFREE	28364549		★☆☆☆☆ Found in Text Mining only
Non-specific early-onset epileptic encephalopathy	Non-Specifi Epileptic Encephalopathy	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nystagmus	Nystagmus	HPO_DG			★☆☆☆☆ Found in Text Mining only
Optic Atrophy	Optic Atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Ptosis	Ptosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	CTD_human_DG	21822266		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Status Epilepticus	Status Epilepticus	HPO_DG			★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach Neoplasms	LHGDN	18986759		★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	28388658	Associate	★☆☆☆☆ Found in Text Mining only