Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	22839
Gene name	DLG associated protein 4
Gene symbol	DLGAP4
Synonyms (NCBI Gene)	DAP-4DAP4DLP4SAPAP-4SAPAP4
Chromosome	20
Chromosome location	20q11.23
Summary	The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein e

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Show/Hide all (310)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028927	hsa-miR-26b-5p	Microarray	19088304
MIRT052886	hsa-miR-3909	CLASH	23622248
MIRT478090	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT478089	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT478088	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT478087	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT478086	hsa-miR-4306	PAR-CLIP	23592263
MIRT478084	hsa-miR-4644	PAR-CLIP	23592263
MIRT478085	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT478083	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT478082	hsa-miR-1228-5p	PAR-CLIP	23592263
MIRT440807	hsa-miR-377-5p	HITS-CLIP	24374217
MIRT440807	hsa-miR-377-5p	HITS-CLIP	24374217
MIRT478090	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT478089	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT478088	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT478087	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT478086	hsa-miR-4306	PAR-CLIP	23592263
MIRT478084	hsa-miR-4644	PAR-CLIP	23592263
MIRT478085	hsa-miR-6721-5p	PAR-CLIP	23592263
MIRT478083	hsa-miR-486-3p	PAR-CLIP	23592263
MIRT478082	hsa-miR-1228-5p	PAR-CLIP	23592263
MIRT938638	hsa-miR-1285	CLIP-seq
MIRT938639	hsa-miR-296-5p	CLIP-seq
MIRT938640	hsa-miR-3187-5p	CLIP-seq
MIRT938641	hsa-miR-4257	CLIP-seq
MIRT938642	hsa-miR-4505	CLIP-seq
MIRT938643	hsa-miR-485-5p	CLIP-seq
MIRT938644	hsa-miR-612	CLIP-seq
MIRT938645	hsa-miR-938	CLIP-seq
MIRT938646	hsa-miR-1207-5p	CLIP-seq
MIRT938647	hsa-miR-1228	CLIP-seq
MIRT938648	hsa-miR-1229	CLIP-seq
MIRT938649	hsa-miR-1269	CLIP-seq
MIRT938650	hsa-miR-1269b	CLIP-seq
MIRT938651	hsa-miR-1288	CLIP-seq
MIRT938652	hsa-miR-1321	CLIP-seq
MIRT938653	hsa-miR-2110	CLIP-seq
MIRT938654	hsa-miR-30a	CLIP-seq
MIRT938655	hsa-miR-30b	CLIP-seq
MIRT938656	hsa-miR-30c	CLIP-seq
MIRT938657	hsa-miR-30d	CLIP-seq
MIRT938658	hsa-miR-30e	CLIP-seq
MIRT938659	hsa-miR-3126-5p	CLIP-seq
MIRT938660	hsa-miR-3153	CLIP-seq
MIRT938661	hsa-miR-3173-3p	CLIP-seq
MIRT938662	hsa-miR-3184	CLIP-seq
MIRT938663	hsa-miR-3192	CLIP-seq
MIRT938664	hsa-miR-3199	CLIP-seq
MIRT938665	hsa-miR-320a	CLIP-seq
MIRT938666	hsa-miR-320b	CLIP-seq
MIRT938667	hsa-miR-320c	CLIP-seq
MIRT938668	hsa-miR-320d	CLIP-seq
MIRT938669	hsa-miR-320e	CLIP-seq
MIRT938670	hsa-miR-329	CLIP-seq
MIRT938671	hsa-miR-342-3p	CLIP-seq
MIRT938672	hsa-miR-3613-3p	CLIP-seq
MIRT938673	hsa-miR-362-3p	CLIP-seq
MIRT938674	hsa-miR-3647-3p	CLIP-seq
MIRT938675	hsa-miR-3665	CLIP-seq
MIRT938676	hsa-miR-3689a-3p	CLIP-seq
MIRT938677	hsa-miR-3689c	CLIP-seq
MIRT938678	hsa-miR-3941	CLIP-seq
MIRT938679	hsa-miR-3974	CLIP-seq
MIRT938680	hsa-miR-423-5p	CLIP-seq
MIRT938681	hsa-miR-4271	CLIP-seq
MIRT938682	hsa-miR-4294	CLIP-seq
MIRT938683	hsa-miR-4429	CLIP-seq
MIRT938684	hsa-miR-4433	CLIP-seq
MIRT938685	hsa-miR-4436b-3p	CLIP-seq
MIRT938686	hsa-miR-4515	CLIP-seq
MIRT938687	hsa-miR-4529-3p	CLIP-seq
MIRT938688	hsa-miR-4667-5p	CLIP-seq
MIRT938689	hsa-miR-4688	CLIP-seq
MIRT938690	hsa-miR-4700-5p	CLIP-seq
MIRT938691	hsa-miR-4706	CLIP-seq
MIRT938692	hsa-miR-4725-3p	CLIP-seq
MIRT938693	hsa-miR-4728-5p	CLIP-seq
MIRT938694	hsa-miR-4729	CLIP-seq
MIRT938695	hsa-miR-4731-5p	CLIP-seq
MIRT938696	hsa-miR-4736	CLIP-seq
MIRT938697	hsa-miR-4739	CLIP-seq
MIRT938698	hsa-miR-4740-5p	CLIP-seq
MIRT938699	hsa-miR-4749-5p	CLIP-seq
MIRT938700	hsa-miR-4756-5p	CLIP-seq
MIRT938701	hsa-miR-4761-5p	CLIP-seq
MIRT938702	hsa-miR-4763-3p	CLIP-seq
MIRT938703	hsa-miR-4777-3p	CLIP-seq
MIRT938704	hsa-miR-4779	CLIP-seq
MIRT938705	hsa-miR-4781-5p	CLIP-seq
MIRT938706	hsa-miR-516b	CLIP-seq
MIRT938707	hsa-miR-542-5p	CLIP-seq
MIRT938708	hsa-miR-603	CLIP-seq
MIRT938709	hsa-miR-643	CLIP-seq
MIRT938710	hsa-miR-648	CLIP-seq
MIRT938711	hsa-miR-711	CLIP-seq
MIRT938712	hsa-miR-764	CLIP-seq
MIRT938645	hsa-miR-938	CLIP-seq
MIRT938646	hsa-miR-1207-5p	CLIP-seq
MIRT938713	hsa-miR-1304	CLIP-seq
MIRT938714	hsa-miR-1827	CLIP-seq
MIRT938715	hsa-miR-185	CLIP-seq
MIRT938716	hsa-miR-1976	CLIP-seq
MIRT938717	hsa-miR-3121-3p	CLIP-seq
MIRT938718	hsa-miR-3170	CLIP-seq
MIRT938675	hsa-miR-3665	CLIP-seq
MIRT938719	hsa-miR-448	CLIP-seq
MIRT938720	hsa-miR-455-5p	CLIP-seq
MIRT938721	hsa-miR-4643	CLIP-seq
MIRT938722	hsa-miR-466	CLIP-seq
MIRT938691	hsa-miR-4706	CLIP-seq
MIRT938723	hsa-miR-4722-3p	CLIP-seq
MIRT938696	hsa-miR-4736	CLIP-seq
MIRT938724	hsa-miR-4740-3p	CLIP-seq
MIRT938699	hsa-miR-4749-5p	CLIP-seq
MIRT938725	hsa-miR-4755-3p	CLIP-seq
MIRT938702	hsa-miR-4763-3p	CLIP-seq
MIRT938726	hsa-miR-4773	CLIP-seq
MIRT938727	hsa-miR-4789-3p	CLIP-seq
MIRT938728	hsa-miR-4797-5p	CLIP-seq
MIRT938729	hsa-miR-744	CLIP-seq
MIRT938712	hsa-miR-764	CLIP-seq
MIRT938645	hsa-miR-938	CLIP-seq
MIRT938646	hsa-miR-1207-5p	CLIP-seq
MIRT938649	hsa-miR-1269	CLIP-seq
MIRT938650	hsa-miR-1269b	CLIP-seq
MIRT1977699	hsa-miR-1281	CLIP-seq
MIRT938651	hsa-miR-1288	CLIP-seq
MIRT1977700	hsa-miR-1294	CLIP-seq
MIRT938652	hsa-miR-1321	CLIP-seq
MIRT938715	hsa-miR-185	CLIP-seq
MIRT1977701	hsa-miR-1908	CLIP-seq
MIRT1977702	hsa-miR-1915	CLIP-seq
MIRT938639	hsa-miR-296-5p	CLIP-seq
MIRT938654	hsa-miR-30a	CLIP-seq
MIRT938655	hsa-miR-30b	CLIP-seq
MIRT938656	hsa-miR-30c	CLIP-seq
MIRT938657	hsa-miR-30d	CLIP-seq
MIRT938658	hsa-miR-30e	CLIP-seq
MIRT1977703	hsa-miR-3117-5p	CLIP-seq
MIRT1977704	hsa-miR-3191	CLIP-seq
MIRT938663	hsa-miR-3192	CLIP-seq
MIRT1977705	hsa-miR-3197	CLIP-seq
MIRT1977706	hsa-miR-3620	CLIP-seq
MIRT938675	hsa-miR-3665	CLIP-seq
MIRT938679	hsa-miR-3974	CLIP-seq
MIRT1977707	hsa-miR-4292	CLIP-seq
MIRT1977708	hsa-miR-4316	CLIP-seq
MIRT1977709	hsa-miR-4446-3p	CLIP-seq
MIRT1977710	hsa-miR-4468	CLIP-seq
MIRT1977711	hsa-miR-4481	CLIP-seq
MIRT1977712	hsa-miR-4492	CLIP-seq
MIRT1977713	hsa-miR-4498	CLIP-seq
MIRT938686	hsa-miR-4515	CLIP-seq
MIRT1977714	hsa-miR-4520a-5p	CLIP-seq
MIRT1977715	hsa-miR-4520b-5p	CLIP-seq
MIRT938687	hsa-miR-4529-3p	CLIP-seq
MIRT1977716	hsa-miR-4654	CLIP-seq
MIRT1977717	hsa-miR-4685-5p	CLIP-seq
MIRT938691	hsa-miR-4706	CLIP-seq
MIRT938693	hsa-miR-4728-5p	CLIP-seq
MIRT938696	hsa-miR-4736	CLIP-seq
MIRT938697	hsa-miR-4739	CLIP-seq
MIRT938698	hsa-miR-4740-5p	CLIP-seq
MIRT1977718	hsa-miR-4745-5p	CLIP-seq
MIRT938699	hsa-miR-4749-5p	CLIP-seq
MIRT938700	hsa-miR-4756-5p	CLIP-seq
MIRT938702	hsa-miR-4763-3p	CLIP-seq
MIRT1977719	hsa-miR-4769-5p	CLIP-seq
MIRT938728	hsa-miR-4797-5p	CLIP-seq
MIRT1977720	hsa-miR-566	CLIP-seq
MIRT938709	hsa-miR-643	CLIP-seq
MIRT938710	hsa-miR-648	CLIP-seq
MIRT1977721	hsa-miR-663	CLIP-seq
MIRT938729	hsa-miR-744	CLIP-seq
MIRT1977722	hsa-miR-762	CLIP-seq
MIRT938712	hsa-miR-764	CLIP-seq
MIRT1977723	hsa-miR-933	CLIP-seq
MIRT938645	hsa-miR-938	CLIP-seq
MIRT1977724	hsa-miR-326	CLIP-seq
MIRT1977725	hsa-miR-330-5p	CLIP-seq
MIRT2213014	hsa-miR-1265	CLIP-seq
MIRT2213015	hsa-miR-3605-5p	CLIP-seq
MIRT2213016	hsa-miR-1182	CLIP-seq
MIRT2213017	hsa-miR-1251	CLIP-seq
MIRT2213018	hsa-miR-1266	CLIP-seq
MIRT938649	hsa-miR-1269	CLIP-seq
MIRT938650	hsa-miR-1269b	CLIP-seq
MIRT1977699	hsa-miR-1281	CLIP-seq
MIRT938651	hsa-miR-1288	CLIP-seq
MIRT1977701	hsa-miR-1908	CLIP-seq
MIRT1977702	hsa-miR-1915	CLIP-seq
MIRT2213019	hsa-miR-24	CLIP-seq
MIRT938654	hsa-miR-30a	CLIP-seq
MIRT938655	hsa-miR-30b	CLIP-seq
MIRT938656	hsa-miR-30c	CLIP-seq
MIRT938657	hsa-miR-30d	CLIP-seq
MIRT938658	hsa-miR-30e	CLIP-seq
MIRT1977703	hsa-miR-3117-5p	CLIP-seq
MIRT1977705	hsa-miR-3197	CLIP-seq
MIRT938679	hsa-miR-3974	CLIP-seq
MIRT2213020	hsa-miR-4284	CLIP-seq
MIRT2213021	hsa-miR-4305	CLIP-seq
MIRT1977708	hsa-miR-4316	CLIP-seq
MIRT1977709	hsa-miR-4446-3p	CLIP-seq
MIRT1977712	hsa-miR-4492	CLIP-seq
MIRT1977713	hsa-miR-4498	CLIP-seq
MIRT938686	hsa-miR-4515	CLIP-seq
MIRT2213022	hsa-miR-4518	CLIP-seq
MIRT938687	hsa-miR-4529-3p	CLIP-seq
MIRT1977717	hsa-miR-4685-5p	CLIP-seq
MIRT2213023	hsa-miR-4715-5p	CLIP-seq
MIRT938698	hsa-miR-4740-5p	CLIP-seq
MIRT1977720	hsa-miR-566	CLIP-seq
MIRT938709	hsa-miR-643	CLIP-seq
MIRT938710	hsa-miR-648	CLIP-seq
MIRT1977721	hsa-miR-663	CLIP-seq
MIRT938729	hsa-miR-744	CLIP-seq
MIRT1977722	hsa-miR-762	CLIP-seq
MIRT938645	hsa-miR-938	CLIP-seq
MIRT938649	hsa-miR-1269	CLIP-seq
MIRT938650	hsa-miR-1269b	CLIP-seq
MIRT1977699	hsa-miR-1281	CLIP-seq
MIRT938651	hsa-miR-1288	CLIP-seq
MIRT1977701	hsa-miR-1908	CLIP-seq
MIRT1977702	hsa-miR-1915	CLIP-seq
MIRT938654	hsa-miR-30a	CLIP-seq
MIRT938655	hsa-miR-30b	CLIP-seq
MIRT938656	hsa-miR-30c	CLIP-seq
MIRT938657	hsa-miR-30d	CLIP-seq
MIRT938658	hsa-miR-30e	CLIP-seq
MIRT1977703	hsa-miR-3117-5p	CLIP-seq
MIRT1977705	hsa-miR-3197	CLIP-seq
MIRT1977708	hsa-miR-4316	CLIP-seq
MIRT1977709	hsa-miR-4446-3p	CLIP-seq
MIRT1977710	hsa-miR-4468	CLIP-seq
MIRT1977712	hsa-miR-4492	CLIP-seq
MIRT1977713	hsa-miR-4498	CLIP-seq
MIRT938686	hsa-miR-4515	CLIP-seq
MIRT1977714	hsa-miR-4520a-5p	CLIP-seq
MIRT1977715	hsa-miR-4520b-5p	CLIP-seq
MIRT938687	hsa-miR-4529-3p	CLIP-seq
MIRT1977717	hsa-miR-4685-5p	CLIP-seq
MIRT938698	hsa-miR-4740-5p	CLIP-seq
MIRT1977720	hsa-miR-566	CLIP-seq
MIRT938709	hsa-miR-643	CLIP-seq
MIRT938710	hsa-miR-648	CLIP-seq
MIRT1977721	hsa-miR-663	CLIP-seq
MIRT938729	hsa-miR-744	CLIP-seq
MIRT1977722	hsa-miR-762	CLIP-seq
MIRT1977723	hsa-miR-933	CLIP-seq
MIRT938645	hsa-miR-938	CLIP-seq
MIRT2516882	hsa-miR-1224-5p	CLIP-seq
MIRT2516883	hsa-miR-1289	CLIP-seq
MIRT1977701	hsa-miR-1908	CLIP-seq
MIRT1977702	hsa-miR-1915	CLIP-seq
MIRT1977703	hsa-miR-3117-5p	CLIP-seq
MIRT2516884	hsa-miR-3169	CLIP-seq
MIRT1977705	hsa-miR-3197	CLIP-seq
MIRT938670	hsa-miR-329	CLIP-seq
MIRT2516885	hsa-miR-331-3p	CLIP-seq
MIRT938673	hsa-miR-362-3p	CLIP-seq
MIRT2516886	hsa-miR-3687	CLIP-seq
MIRT938678	hsa-miR-3941	CLIP-seq
MIRT2516887	hsa-miR-4308	CLIP-seq
MIRT2516888	hsa-miR-4313	CLIP-seq
MIRT1977708	hsa-miR-4316	CLIP-seq
MIRT2516889	hsa-miR-4442	CLIP-seq
MIRT1977709	hsa-miR-4446-3p	CLIP-seq
MIRT2516890	hsa-miR-4457	CLIP-seq
MIRT2516891	hsa-miR-4479	CLIP-seq
MIRT1977712	hsa-miR-4492	CLIP-seq
MIRT1977713	hsa-miR-4498	CLIP-seq
MIRT2516892	hsa-miR-4513	CLIP-seq
MIRT2516893	hsa-miR-4632	CLIP-seq
MIRT938722	hsa-miR-466	CLIP-seq
MIRT2516894	hsa-miR-4672	CLIP-seq
MIRT1977717	hsa-miR-4685-5p	CLIP-seq
MIRT2516895	hsa-miR-4707-3p	CLIP-seq
MIRT2516896	hsa-miR-4731-3p	CLIP-seq
MIRT938698	hsa-miR-4740-5p	CLIP-seq
MIRT2516897	hsa-miR-4749-3p	CLIP-seq
MIRT2516898	hsa-miR-4751	CLIP-seq
MIRT2516899	hsa-miR-4786-3p	CLIP-seq
MIRT2516900	hsa-miR-4801	CLIP-seq
MIRT938708	hsa-miR-603	CLIP-seq
MIRT2516901	hsa-miR-624	CLIP-seq
MIRT1977721	hsa-miR-663	CLIP-seq
MIRT2516902	hsa-miR-671-5p	CLIP-seq
MIRT938729	hsa-miR-744	CLIP-seq
MIRT1977722	hsa-miR-762	CLIP-seq
MIRT1977699	hsa-miR-1281	CLIP-seq
MIRT1977701	hsa-miR-1908	CLIP-seq
MIRT1977702	hsa-miR-1915	CLIP-seq
MIRT1977703	hsa-miR-3117-5p	CLIP-seq
MIRT1977705	hsa-miR-3197	CLIP-seq
MIRT1977708	hsa-miR-4316	CLIP-seq
MIRT1977709	hsa-miR-4446-3p	CLIP-seq
MIRT1977712	hsa-miR-4492	CLIP-seq
MIRT1977713	hsa-miR-4498	CLIP-seq
MIRT1977714	hsa-miR-4520a-5p	CLIP-seq
MIRT1977715	hsa-miR-4520b-5p	CLIP-seq
MIRT2516893	hsa-miR-4632	CLIP-seq
MIRT1977717	hsa-miR-4685-5p	CLIP-seq
MIRT2516895	hsa-miR-4707-3p	CLIP-seq
MIRT2516897	hsa-miR-4749-3p	CLIP-seq
MIRT1977720	hsa-miR-566	CLIP-seq
MIRT1977721	hsa-miR-663	CLIP-seq
MIRT938729	hsa-miR-744	CLIP-seq
MIRT1977722	hsa-miR-762	CLIP-seq

Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16275660, 17474147, 32296183
GO:0005886	Component	Plasma membrane	TAS
GO:0016020	Component	Membrane	IEA
GO:0023052	Process	Signaling	IEA
GO:0031594	Component	Neuromuscular junction	IEA
GO:0045202	Component	Synapse	IEA
GO:0050804	Process	Modulation of chemical synaptic transmission	IBA
GO:0060090	Function	Molecular adaptor activity	IBA
GO:0090128	Process	Regulation of synapse maturation	IEA
GO:0098978	Component	Glutamatergic synapse	IBA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0098981	Component	Cholinergic synapse	IEA
GO:0099010	Process	Modification of postsynaptic structure	IEA
GO:0099572	Component	Postsynaptic specialization	IBA
GO:0099572	Component	Postsynaptic specialization	IEA

MIM	HGNC	e!Ensembl
616191	24476	ENSG00000080845

Q9Y2H0

Protein name

Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)

Protein function

May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03359	GKAP	660 → 992	Guanylate-kinase-associated protein (GKAP) protein	Family

Sequence

MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPL
NNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFS
TLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGSKKGGMEDGKGR
RAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERSQPR
YFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLS
HAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIP
CRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLD
SVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYE
AACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTG
SLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVT
SQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAP
KRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQD
ANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPP
DPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLG
KVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFD
ELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRL
LAAKRAASVRQNSATESADSIEIYVPEAQTRL

Sequence length

992

Interactions

View interactions

	Reactome
			Neurexins and neuroligins

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (29)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BASAL CELL CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BILIARY TRACT CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CERVICAL CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CUTANEOUS MELANOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESOPHAGEAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESTROGEN-RECEPTOR NEGATIVE BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GASTRIC CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEPATOCELLULAR CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar GWAS catalog	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
LUNG CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELANOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROBLASTOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-HODGKINS LYMPHOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-MELANOMA SKIN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN ENDOMETRIOID CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN SEROUS CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL LUNG CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UPPER AERODIGESTIVE TRACT NEOPLASM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (16)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	30664629		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	BEFREE	30664629		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	36396671	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebellar Ataxia	Cerebellar ataxia	Pubtator	24986922	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebellar Ataxia, Early Onset	Cerebellar Ataxia	BEFREE	24986922		★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive Disorder	Major depressive disorder	Pubtator	32646340	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	31338326		★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	30664629		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	32646340	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	31338326		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	30365066		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	30365066		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodevelopmental Disorders	Neurodevelopmental Disorders	BEFREE	30664629		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	31761328		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	30365066		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	30365066	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

DLGAP4 (DLG associated protein 4)