HSPA4L (heat shock protein family A (Hsp70) member 4 like)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 22824 |
| Gene name | Heat shock protein family A (Hsp70) member 4 like |
| Gene symbol | HSPA4L |
| Synonyms (NCBI Gene) |
APG-1APG1HSPH3Osp94
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| Chromosome | 4 |
| Chromosome location | 4q28.1 |
| Summary | The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a goo |
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miRNA
miRNA information provided by mirtarbase database.
370
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O95757 | |||||||||||||||
| Protein name | Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Heat shock protein family H member 3) (Heat-shock protein family A member 4-like protein) (HSPA4-like protein) (Osmotic stress protein 94) | |||||||||||||||
| Protein function | Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase. | |||||||||||||||
| Family and domains |
Pfam
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| Sequence | ||||||||||||||||
| Sequence length | 839 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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