Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	222696
Gene name	Zinc finger and SCAN domain containing 23
Gene symbol	ZSCAN23
Synonyms (NCBI Gene)	ZNF390ZNF453dJ29K1.3dJ29K1.3.1
Chromosome	6
Chromosome location	6p22.1

136

Show/Hide all (136)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017469	hsa-miR-335-5p	Microarray	18185580
MIRT639632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT639631	hsa-miR-3682-5p	HITS-CLIP	23824327
MIRT639630	hsa-miR-7977	HITS-CLIP	23824327
MIRT639629	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT639628	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT639627	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT639626	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT639633	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT639634	hsa-miR-215-3p	HITS-CLIP	23824327
MIRT639632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT639631	hsa-miR-3682-5p	HITS-CLIP	23824327
MIRT639630	hsa-miR-7977	HITS-CLIP	23824327
MIRT639629	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT639628	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT639627	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT639626	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT639632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT639631	hsa-miR-3682-5p	HITS-CLIP	23824327
MIRT639630	hsa-miR-7977	HITS-CLIP	23824327
MIRT639629	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT639628	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT639627	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT639626	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT639633	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT639634	hsa-miR-215-3p	HITS-CLIP	23824327
MIRT639632	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT639631	hsa-miR-3682-5p	HITS-CLIP	23824327
MIRT639630	hsa-miR-7977	HITS-CLIP	23824327
MIRT639629	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT639628	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT639627	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT639626	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT1543711	hsa-miR-1236	CLIP-seq
MIRT1543712	hsa-miR-135a	CLIP-seq
MIRT1543713	hsa-miR-135b	CLIP-seq
MIRT1543714	hsa-miR-3150b-3p	CLIP-seq
MIRT1543715	hsa-miR-3977	CLIP-seq
MIRT1543716	hsa-miR-4252	CLIP-seq
MIRT1543717	hsa-miR-4277	CLIP-seq
MIRT1543718	hsa-miR-4635	CLIP-seq
MIRT1543719	hsa-miR-4689	CLIP-seq
MIRT1543720	hsa-miR-4784	CLIP-seq
MIRT1543721	hsa-miR-4803	CLIP-seq
MIRT1543722	hsa-miR-502-5p	CLIP-seq
MIRT1543723	hsa-miR-513a-3p	CLIP-seq
MIRT1543724	hsa-miR-548c-3p	CLIP-seq
MIRT1543725	hsa-miR-590-3p	CLIP-seq
MIRT1543726	hsa-miR-604	CLIP-seq
MIRT1543727	hsa-miR-647	CLIP-seq
MIRT1543728	hsa-miR-942	CLIP-seq
MIRT1555876	hsa-miR-146a	CLIP-seq
MIRT1555877	hsa-miR-146b-5p	CLIP-seq
MIRT1555878	hsa-miR-3171	CLIP-seq
MIRT1555879	hsa-miR-383	CLIP-seq
MIRT1555880	hsa-miR-3919	CLIP-seq
MIRT1555881	hsa-miR-3925-5p	CLIP-seq
MIRT1555882	hsa-miR-4756-3p	CLIP-seq
MIRT1555883	hsa-miR-4772-5p	CLIP-seq
MIRT2164067	hsa-miR-1197	CLIP-seq
MIRT2164068	hsa-miR-154	CLIP-seq
MIRT2164069	hsa-miR-214	CLIP-seq
MIRT2164070	hsa-miR-3125	CLIP-seq
MIRT2164071	hsa-miR-3607-3p	CLIP-seq
MIRT2164072	hsa-miR-3619-5p	CLIP-seq
MIRT2164073	hsa-miR-3690	CLIP-seq
MIRT2164074	hsa-miR-378	CLIP-seq
MIRT2164075	hsa-miR-378b	CLIP-seq
MIRT2164076	hsa-miR-378c	CLIP-seq
MIRT2164077	hsa-miR-378d	CLIP-seq
MIRT2164078	hsa-miR-378e	CLIP-seq
MIRT2164079	hsa-miR-378f	CLIP-seq
MIRT2164080	hsa-miR-378h	CLIP-seq
MIRT2164081	hsa-miR-378i	CLIP-seq
MIRT2164082	hsa-miR-3916	CLIP-seq
MIRT2164083	hsa-miR-3973	CLIP-seq
MIRT2164084	hsa-miR-422a	CLIP-seq
MIRT2164085	hsa-miR-4254	CLIP-seq
MIRT2164086	hsa-miR-520d-5p	CLIP-seq
MIRT2164087	hsa-miR-524-5p	CLIP-seq
MIRT2164088	hsa-miR-548a-5p	CLIP-seq
MIRT2164089	hsa-miR-548ab	CLIP-seq
MIRT2164090	hsa-miR-548ak	CLIP-seq
MIRT2164091	hsa-miR-548b-5p	CLIP-seq
MIRT2164092	hsa-miR-548c-5p	CLIP-seq
MIRT2164093	hsa-miR-548d-5p	CLIP-seq
MIRT2164094	hsa-miR-548h	CLIP-seq
MIRT2164095	hsa-miR-548i	CLIP-seq
MIRT2164096	hsa-miR-548j	CLIP-seq
MIRT2164097	hsa-miR-548w	CLIP-seq
MIRT2164098	hsa-miR-548y	CLIP-seq
MIRT2164099	hsa-miR-559	CLIP-seq
MIRT2164100	hsa-miR-761	CLIP-seq
MIRT2164101	hsa-miR-877	CLIP-seq
MIRT2164067	hsa-miR-1197	CLIP-seq
MIRT2164069	hsa-miR-214	CLIP-seq
MIRT2164070	hsa-miR-3125	CLIP-seq
MIRT2164072	hsa-miR-3619-5p	CLIP-seq
MIRT2164082	hsa-miR-3916	CLIP-seq
MIRT2164083	hsa-miR-3973	CLIP-seq
MIRT2164088	hsa-miR-548a-5p	CLIP-seq
MIRT2164089	hsa-miR-548ab	CLIP-seq
MIRT2164090	hsa-miR-548ak	CLIP-seq
MIRT2164091	hsa-miR-548b-5p	CLIP-seq
MIRT2164092	hsa-miR-548c-5p	CLIP-seq
MIRT2164093	hsa-miR-548d-5p	CLIP-seq
MIRT2164094	hsa-miR-548h	CLIP-seq
MIRT2164095	hsa-miR-548i	CLIP-seq
MIRT2164096	hsa-miR-548j	CLIP-seq
MIRT2164097	hsa-miR-548w	CLIP-seq
MIRT2164098	hsa-miR-548y	CLIP-seq
MIRT2164099	hsa-miR-559	CLIP-seq
MIRT2164100	hsa-miR-761	CLIP-seq
MIRT2164101	hsa-miR-877	CLIP-seq
MIRT2164067	hsa-miR-1197	CLIP-seq
MIRT2164069	hsa-miR-214	CLIP-seq
MIRT2164070	hsa-miR-3125	CLIP-seq
MIRT2164072	hsa-miR-3619-5p	CLIP-seq
MIRT2164082	hsa-miR-3916	CLIP-seq
MIRT2164083	hsa-miR-3973	CLIP-seq
MIRT2164088	hsa-miR-548a-5p	CLIP-seq
MIRT2164089	hsa-miR-548ab	CLIP-seq
MIRT2164090	hsa-miR-548ak	CLIP-seq
MIRT2164091	hsa-miR-548b-5p	CLIP-seq
MIRT2164092	hsa-miR-548c-5p	CLIP-seq
MIRT2164093	hsa-miR-548d-5p	CLIP-seq
MIRT2164094	hsa-miR-548h	CLIP-seq
MIRT2164095	hsa-miR-548i	CLIP-seq
MIRT2164096	hsa-miR-548j	CLIP-seq
MIRT2164097	hsa-miR-548w	CLIP-seq
MIRT2164098	hsa-miR-548y	CLIP-seq
MIRT2164099	hsa-miR-559	CLIP-seq
MIRT2164100	hsa-miR-761	CLIP-seq
MIRT2164101	hsa-miR-877	CLIP-seq
MIRT2696441	hsa-miR-4475	CLIP-seq
MIRT1543723	hsa-miR-513a-3p	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q3MJ62

Protein name

Zinc finger and SCAN domain-containing protein 23 (Zinc finger protein 390) (Zinc finger protein 453)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02023	SCAN	44 → 133	SCAN domain	Domain
PF00096	zf-C2H2	249 → 271	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	277 → 299	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	305 → 327	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	333 → 355	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	361 → 383	Zinc finger, C2H2 type	Domain

Sequence

MAITLTLQTAEMQEGLLAVKVKEEEEEHSCGPESGLSRNNPHTREIFRRRFRQFCYQESP
GPREALQRLQELCHQWLRPEMHTKEQILELLVLEQFLTILPEELQAWVRQHRPVSGEEAV
TVLEDLERELDDPGEQVLSHAHEQEEFVKEKATPGAAQESSNDQFQTLEEQLGYNLREVC
PVQEIDGKAGTWNVELAPKREISQEVKSLIQVLGKQNGNITQIPEYGDTCDREGRLEKQR
VSSSVERPYICSECGKSFTQNSILIEHQRTHTGEKPYECDECGRAFSQRSGLFQHQRLHT
GEKRYQCSVCGKAFSQNAGLFHHLRIHTGEKPYQCNQCNKSFSRRSVLIKHQRIHTGERP
YECEECGKNFIYHCNLIQHRKVHPVAESS

Sequence length

389

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE SCLEROSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SYSTEMIC LUPUS ERYTHEMATOSUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Schizophrenia	Schizophrenia	GWASCAT_DG	31268507		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

ZSCAN23 (zinc finger and SCAN domain containing 23)