LRRC63 (leucine rich repeat containing 63)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 220416
Gene name Leucine rich repeat containing 63
Gene symbol LRRC63
Synonyms (NCBI Gene)
-
Chromosome 13
Chromosome location 13q14.13
miRNA miRNA information provided by mirtarbase database.
36
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (36)
miRTarBase ID miRNA Experiments Reference
MIRT514214 hsa-miR-1277-5p HITS-CLIP 21572407
MIRT514208 hsa-miR-410-3p HITS-CLIP 21572407
MIRT514207 hsa-miR-5011-5p HITS-CLIP 21572407
MIRT514204 hsa-miR-190a-3p HITS-CLIP 21572407
MIRT514216 hsa-miR-548at-5p PAR-CLIP 23446348
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (1)
GO ID Ontology Definition Evidence Reference
GO:0035556 Process Intracellular signal transduction IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q05C16
Protein name Leucine-rich repeat-containing protein 63
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13855 LRR_8 392 → 449 Leucine rich repeat Repeat
Sequence 
MQKPPLLLRRPLPPKFTKLSLHEKKTHTAKTGKIESLHVAFTEDETTSIKMDRTRFPDVL
RNQSLTPINIQNIFLDHCVQERVTAISSPQKSTKHVREQIPDTATGSIFFPHCNSASTRI
FGKQTNKMESSRKFKTMKDVYTEKRLENILILSSKFSKPKSTPGSVIAQKLEKMHPKHQP
LPESPGYTYQHISRDLSATVPSPPPMTVSMKPEGQWPEHFKSTATLTLRVTEFPGFVSLP
TPVLPRKPHRQSVIETLVTENGNIESVPKQIPPRPPEGLTKTEKIESEIHVVRGEGFKTV
AATRYETITAMTNLAIVNCQVYGRNALNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYF
PTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELD
VSYNELTFIPNEIQKLRSLEKLTVDGNELSFFPHGILKLNLTKIQFENNFTHPCFWRDNY
LNNPQQLTQIISLFIVQNKLHKFYDKIPVEVQKLLKWGAQFLTELAPLSIYSSRKAITEG
YIAVELPKFEESKNITEGLLTQKRYEEVMVKCINATTVTS
Sequence length 580
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (2)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATRIAL FIBRILLATION — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CLONAL HEMATOPOIESIS — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (3)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Atrial Fibrillation Atrial fibrillation Pubtator 17903304 Associate
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Cardiovascular Diseases Cardiovascular disease Pubtator 17903304 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Heart Failure Heart failure Pubtator 17903304 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only