Gene Gene information from NCBI Gene database.
Entrez ID 202052
Gene name DnaJ heat shock protein family (Hsp40) member C18
Gene symbol DNAJC18
Synonyms (NCBI Gene)
-
Chromosome 5
Chromosome location 5q31.2
miRNA miRNA information provided by mirtarbase database.
698
miRTarBase ID miRNA Experiments Reference
MIRT023268 hsa-miR-122-5p Microarray 17612493
MIRT706947 hsa-miR-4438 HITS-CLIP 21572407
MIRT706946 hsa-miR-455-5p HITS-CLIP 21572407
MIRT706945 hsa-miR-4740-3p HITS-CLIP 21572407
MIRT706944 hsa-miR-6778-3p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8
GO ID Ontology Definition Evidence Reference
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IBA
GO:0005789 Component Endoplasmic reticulum membrane IDA 25631089
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0006457 Process Protein folding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
621108 28429 ENSG00000170464
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H819
Protein name DnaJ homolog subfamily C member 18
Protein function (Microbial infection) In case of infection by polyomavirus, involved in the virus endoplasmic reticulum membrane penetration and infection (PubMed:25631089). Regulates the recruitment of DNAJB12:DNAJB14 into SV40-induced foci and all cooperate t
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00226 DnaJ 82 143 DnaJ domain Domain
PF09320 DUF1977 244 350 Domain of unknown function (DUF1977) Family
Sequence
MAATLGSGERWTEAYIDAVRRNKYPEDTPPESHDPCGCCNCMKAQKEKKSENEWTQTRQG
EGNSTYSEEQLLGVQRIKKCRNYYEILGVSRDASDEELKKAYRKLALKFHPDKNCAPGAT
DAFKAIGNAFAVLSNPDKRLRYD
EYGDEQVTFTAPRARPYNYYRDFEADITPEELFNVFF
GGHFPTGNIHMFSNVTDDTYYYRRRHRHERTQTQKEEEEEKPQTTYSAFIQLLPVLVIVI
ISVITQLLATNPPYSLFYKSTLGYTISRETQNLQVPYFVDKNFDKAYRGASLHDLEKTIE
KDYIDYIQTSCWKEKQQKSELTNLAGLYRDERLKQKAESLKLENCEKLSK
LIGLRRGG
Sequence length 358
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
DILATED CARDIOMYOPATHY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HEART FAILURE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYPERTROPHIC CARDIOMYOPATHY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations