CDCP2 (CUB domain containing protein 2)

Gene

• Entrez ID: 200008
• Gene name: CUB domain containing protein 2
• Gene symbol: CDCP2
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1p32.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT879266	hsa-miR-1207-3p	CLIP-seq
MIRT879267	hsa-miR-1252	CLIP-seq
MIRT879268	hsa-miR-1276	CLIP-seq
MIRT879269	hsa-miR-129-5p	CLIP-seq
MIRT879270	hsa-miR-1301	CLIP-seq
MIRT879271	hsa-miR-1915	CLIP-seq
MIRT879272	hsa-miR-3161	CLIP-seq
MIRT879273	hsa-miR-338-5p	CLIP-seq
MIRT879274	hsa-miR-3914	CLIP-seq
MIRT879275	hsa-miR-4271	CLIP-seq
MIRT879276	hsa-miR-4311	CLIP-seq
MIRT879277	hsa-miR-4533	CLIP-seq
MIRT879278	hsa-miR-4640-5p	CLIP-seq
MIRT879279	hsa-miR-4659a-5p	CLIP-seq
MIRT879280	hsa-miR-4659b-5p	CLIP-seq
MIRT879281	hsa-miR-4660	CLIP-seq
MIRT879282	hsa-miR-4716-3p	CLIP-seq
MIRT879283	hsa-miR-4725-3p	CLIP-seq
MIRT879284	hsa-miR-4726-5p	CLIP-seq
MIRT879285	hsa-miR-4747-5p	CLIP-seq
MIRT879286	hsa-miR-4776-3p	CLIP-seq
MIRT879287	hsa-miR-5047	CLIP-seq
MIRT879288	hsa-miR-583	CLIP-seq
MIRT879289	hsa-miR-625	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: 612320
• HGNC: 27297
• e!Ensembl: ENSG00000157211

Protein

• UniProt ID: Q5VXM1
• Protein name: CUB domain-containing protein 2
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00431	CUB	30 → 140	CUB domain	Domain
  PF00431	CUB	145 → 252	CUB domain	Domain
  PF00431	CUB	257 → 370	CUB domain	Domain

• Sequence:

  MLAEWGACLLLAVALLGPGLQAQAMEGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLI
  VVAEGSSVLLTFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHV
  MSVIFHSDKHVASHGFSAGYQKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGP
  AHVKLVFVDFQVEGNEECTYDYVAVLGGPGPTRGHHYCGSTRPPTLVSLGHELQVVFKSD
  FNIGGRGFKAYYFSGECQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFL
  DLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRS
  TTRRGFSVAYIGGQLGCGSGSTEGEGEALQPQSLQSPSSIPPVCPAPPMNGLLQLLLHWL
  HPCPLSGPLRLDGTAPACFHYCRASFPSF

• Sequence length: 449

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HODGKINS LYMPHOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Parkinson Disease	Parkinson disease	BEFREE	17388942		★☆☆☆☆ Found in Text Mining only
Seizures	Seizures	Pubtator	27251580	Associate	★☆☆☆☆ Found in Text Mining only