Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID	2000
Gene name	E74 like ETS transcription factor 4
Gene symbol	ELF4
Synonyms (NCBI Gene)	AIFBL2ELFRMEF
Chromosome	X
Chromosome location	Xq26.1
Summary	The protein encoded by this gene is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction o

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miRTarBase ID	miRNA	Experiments	Reference
MIRT002580	hsa-miR-124-3p	Microarray	15685193
MIRT002580	hsa-miR-124-3p	Microarray	15685193
MIRT002580	hsa-miR-124-3p	Microarray	18668037
MIRT029730	hsa-miR-26b-5p	Microarray	19088304
MIRT050308	hsa-miR-25-3p	CLASH	23622248
MIRT049601	hsa-miR-92a-3p	CLASH	23622248
MIRT041006	hsa-miR-505-3p	CLASH	23622248
MIRT039637	hsa-miR-615-3p	CLASH	23622248
MIRT037325	hsa-miR-877-5p	CLASH	23622248
MIRT054390	hsa-let-7f-5p	Luciferase reporter assay	22894925
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	20371350
MIRT517306	hsa-miR-4464	PAR-CLIP	20371350
MIRT517305	hsa-miR-4748	PAR-CLIP	20371350
MIRT517304	hsa-miR-298	PAR-CLIP	20371350
MIRT517303	hsa-miR-3665	PAR-CLIP	20371350
MIRT517302	hsa-miR-657	PAR-CLIP	20371350
MIRT517301	hsa-miR-5087	PAR-CLIP	20371350
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT517299	hsa-miR-143-5p	PAR-CLIP	20371350
MIRT517298	hsa-miR-8068	PAR-CLIP	20371350
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	20371350
MIRT517306	hsa-miR-4464	PAR-CLIP	20371350
MIRT517305	hsa-miR-4748	PAR-CLIP	20371350
MIRT517304	hsa-miR-298	PAR-CLIP	20371350
MIRT517303	hsa-miR-3665	PAR-CLIP	20371350
MIRT517302	hsa-miR-657	PAR-CLIP	20371350
MIRT517301	hsa-miR-5087	PAR-CLIP	20371350
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT517299	hsa-miR-143-5p	PAR-CLIP	20371350
MIRT517298	hsa-miR-8068	PAR-CLIP	20371350
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT517306	hsa-miR-4464	PAR-CLIP	21572407
MIRT517305	hsa-miR-4748	PAR-CLIP	21572407
MIRT517304	hsa-miR-298	PAR-CLIP	21572407
MIRT517303	hsa-miR-3665	PAR-CLIP	21572407
MIRT517302	hsa-miR-657	PAR-CLIP	21572407
MIRT517301	hsa-miR-5087	PAR-CLIP	21572407
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT517299	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT517298	hsa-miR-8068	PAR-CLIP	21572407
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT517306	hsa-miR-4464	PAR-CLIP	21572407
MIRT517305	hsa-miR-4748	PAR-CLIP	21572407
MIRT517304	hsa-miR-298	PAR-CLIP	21572407
MIRT517303	hsa-miR-3665	PAR-CLIP	21572407
MIRT517302	hsa-miR-657	PAR-CLIP	21572407
MIRT517301	hsa-miR-5087	PAR-CLIP	21572407
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT517299	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT517298	hsa-miR-8068	PAR-CLIP	21572407
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	23446348
MIRT517307	hsa-miR-4678	PAR-CLIP	23446348
MIRT517306	hsa-miR-4464	PAR-CLIP	23446348
MIRT517305	hsa-miR-4748	PAR-CLIP	23446348
MIRT517304	hsa-miR-298	PAR-CLIP	23446348
MIRT517303	hsa-miR-3665	PAR-CLIP	23446348
MIRT517302	hsa-miR-657	PAR-CLIP	23446348
MIRT517301	hsa-miR-5087	PAR-CLIP	23446348
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	23446348
MIRT517299	hsa-miR-143-5p	PAR-CLIP	23446348
MIRT517298	hsa-miR-8068	PAR-CLIP	23446348
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	23446348
MIRT517296	hsa-miR-331-5p	PAR-CLIP	23446348
MIRT002580	hsa-miR-124-3p	Luciferase reporter assayRNA-seqqRT-PCR	31624087
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	20371350
MIRT517306	hsa-miR-4464	PAR-CLIP	20371350
MIRT517305	hsa-miR-4748	PAR-CLIP	20371350
MIRT517304	hsa-miR-298	PAR-CLIP	20371350
MIRT517303	hsa-miR-3665	PAR-CLIP	20371350
MIRT517302	hsa-miR-657	PAR-CLIP	20371350
MIRT517301	hsa-miR-5087	PAR-CLIP	20371350
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT517299	hsa-miR-143-5p	PAR-CLIP	20371350
MIRT517298	hsa-miR-8068	PAR-CLIP	20371350
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	20371350
MIRT517306	hsa-miR-4464	PAR-CLIP	20371350
MIRT517305	hsa-miR-4748	PAR-CLIP	20371350
MIRT517304	hsa-miR-298	PAR-CLIP	20371350
MIRT517303	hsa-miR-3665	PAR-CLIP	20371350
MIRT517302	hsa-miR-657	PAR-CLIP	20371350
MIRT517301	hsa-miR-5087	PAR-CLIP	20371350
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT517299	hsa-miR-143-5p	PAR-CLIP	20371350
MIRT517298	hsa-miR-8068	PAR-CLIP	20371350
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT517306	hsa-miR-4464	PAR-CLIP	21572407
MIRT517305	hsa-miR-4748	PAR-CLIP	21572407
MIRT517304	hsa-miR-298	PAR-CLIP	21572407
MIRT517303	hsa-miR-3665	PAR-CLIP	21572407
MIRT517302	hsa-miR-657	PAR-CLIP	21572407
MIRT517301	hsa-miR-5087	PAR-CLIP	21572407
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT517299	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT517298	hsa-miR-8068	PAR-CLIP	21572407
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT517306	hsa-miR-4464	PAR-CLIP	21572407
MIRT517305	hsa-miR-4748	PAR-CLIP	21572407
MIRT517304	hsa-miR-298	PAR-CLIP	21572407
MIRT517303	hsa-miR-3665	PAR-CLIP	21572407
MIRT517302	hsa-miR-657	PAR-CLIP	21572407
MIRT517301	hsa-miR-5087	PAR-CLIP	21572407
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT517299	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT517298	hsa-miR-8068	PAR-CLIP	21572407
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT517308	hsa-miR-376c-3p	PAR-CLIP	23446348
MIRT517307	hsa-miR-4678	PAR-CLIP	23446348
MIRT517306	hsa-miR-4464	PAR-CLIP	23446348
MIRT517305	hsa-miR-4748	PAR-CLIP	23446348
MIRT517304	hsa-miR-298	PAR-CLIP	23446348
MIRT517303	hsa-miR-3665	PAR-CLIP	23446348
MIRT517302	hsa-miR-657	PAR-CLIP	23446348
MIRT517301	hsa-miR-5087	PAR-CLIP	23446348
MIRT517300	hsa-miR-3944-5p	PAR-CLIP	23446348
MIRT517299	hsa-miR-143-5p	PAR-CLIP	23446348
MIRT517298	hsa-miR-8068	PAR-CLIP	23446348
MIRT517297	hsa-miR-4666a-5p	PAR-CLIP	23446348
MIRT517296	hsa-miR-331-5p	PAR-CLIP	23446348
MIRT960032	hsa-let-7a	CLIP-seq
MIRT960033	hsa-let-7b	CLIP-seq
MIRT960034	hsa-let-7c	CLIP-seq
MIRT960035	hsa-let-7d	CLIP-seq
MIRT960036	hsa-let-7e	CLIP-seq
MIRT960037	hsa-let-7f	CLIP-seq
MIRT960038	hsa-let-7g	CLIP-seq
MIRT960039	hsa-let-7i	CLIP-seq
MIRT960040	hsa-miR-1193	CLIP-seq
MIRT960041	hsa-miR-1197	CLIP-seq
MIRT960042	hsa-miR-1207-5p	CLIP-seq
MIRT960043	hsa-miR-1226	CLIP-seq
MIRT960044	hsa-miR-124	CLIP-seq
MIRT960045	hsa-miR-1247	CLIP-seq
MIRT960046	hsa-miR-1252	CLIP-seq
MIRT960047	hsa-miR-1253	CLIP-seq
MIRT960048	hsa-miR-1256	CLIP-seq
MIRT960049	hsa-miR-1273g	CLIP-seq
MIRT960050	hsa-miR-128	CLIP-seq
MIRT960051	hsa-miR-1287	CLIP-seq
MIRT960052	hsa-miR-1321	CLIP-seq
MIRT960053	hsa-miR-134	CLIP-seq
MIRT960054	hsa-miR-143	CLIP-seq
MIRT960055	hsa-miR-1470	CLIP-seq
MIRT960056	hsa-miR-155	CLIP-seq
MIRT960057	hsa-miR-186	CLIP-seq
MIRT960058	hsa-miR-1909	CLIP-seq
MIRT960059	hsa-miR-1911	CLIP-seq
MIRT960060	hsa-miR-196a	CLIP-seq
MIRT960061	hsa-miR-196b	CLIP-seq
MIRT960062	hsa-miR-203	CLIP-seq
MIRT960063	hsa-miR-204	CLIP-seq
MIRT960064	hsa-miR-211	CLIP-seq
MIRT960065	hsa-miR-224	CLIP-seq
MIRT960066	hsa-miR-2276	CLIP-seq
MIRT960067	hsa-miR-23a	CLIP-seq
MIRT960068	hsa-miR-23b	CLIP-seq
MIRT960069	hsa-miR-23c	CLIP-seq
MIRT960070	hsa-miR-3118	CLIP-seq
MIRT960071	hsa-miR-3119	CLIP-seq
MIRT960072	hsa-miR-3120-3p	CLIP-seq
MIRT960073	hsa-miR-3123	CLIP-seq
MIRT960074	hsa-miR-3133	CLIP-seq
MIRT960075	hsa-miR-3135	CLIP-seq
MIRT960076	hsa-miR-3135b	CLIP-seq
MIRT960077	hsa-miR-3150b-3p	CLIP-seq
MIRT960078	hsa-miR-3154	CLIP-seq
MIRT960079	hsa-miR-3156-3p	CLIP-seq
MIRT960080	hsa-miR-3157-3p	CLIP-seq
MIRT960081	hsa-miR-3160-3p	CLIP-seq
MIRT960082	hsa-miR-3184	CLIP-seq
MIRT960083	hsa-miR-3185	CLIP-seq
MIRT960084	hsa-miR-323-3p	CLIP-seq
MIRT960085	hsa-miR-329	CLIP-seq
MIRT960086	hsa-miR-342-5p	CLIP-seq
MIRT960087	hsa-miR-3612	CLIP-seq
MIRT960088	hsa-miR-3614-3p	CLIP-seq
MIRT960089	hsa-miR-362-3p	CLIP-seq
MIRT960090	hsa-miR-365	CLIP-seq
MIRT960091	hsa-miR-3681	CLIP-seq
MIRT960092	hsa-miR-3691-5p	CLIP-seq
MIRT960093	hsa-miR-371-5p	CLIP-seq
MIRT960094	hsa-miR-371b-3p	CLIP-seq
MIRT960095	hsa-miR-3913-3p	CLIP-seq
MIRT960096	hsa-miR-3929	CLIP-seq
MIRT960097	hsa-miR-3941	CLIP-seq
MIRT960098	hsa-miR-423-5p	CLIP-seq
MIRT960099	hsa-miR-4261	CLIP-seq
MIRT960100	hsa-miR-4269	CLIP-seq
MIRT960101	hsa-miR-4270	CLIP-seq
MIRT960102	hsa-miR-4271	CLIP-seq
MIRT960103	hsa-miR-4287	CLIP-seq
MIRT960104	hsa-miR-4290	CLIP-seq
MIRT960105	hsa-miR-4301	CLIP-seq
MIRT960106	hsa-miR-4318	CLIP-seq
MIRT960107	hsa-miR-4419a	CLIP-seq
MIRT960108	hsa-miR-4419b	CLIP-seq
MIRT960109	hsa-miR-4434	CLIP-seq
MIRT960110	hsa-miR-4441	CLIP-seq
MIRT960111	hsa-miR-4458	CLIP-seq
MIRT960112	hsa-miR-4459	CLIP-seq
MIRT960113	hsa-miR-4470	CLIP-seq
MIRT960114	hsa-miR-4478	CLIP-seq
MIRT960115	hsa-miR-4479	CLIP-seq
MIRT960116	hsa-miR-4500	CLIP-seq
MIRT960117	hsa-miR-4505	CLIP-seq
MIRT960118	hsa-miR-4510	CLIP-seq
MIRT960119	hsa-miR-4514	CLIP-seq
MIRT960120	hsa-miR-4516	CLIP-seq
MIRT960121	hsa-miR-4639-5p	CLIP-seq
MIRT960122	hsa-miR-4645-5p	CLIP-seq
MIRT960123	hsa-miR-4651	CLIP-seq
MIRT960124	hsa-miR-4662a-3p	CLIP-seq
MIRT960125	hsa-miR-4664-5p	CLIP-seq
MIRT960126	hsa-miR-4667-3p	CLIP-seq
MIRT960127	hsa-miR-4673	CLIP-seq
MIRT960128	hsa-miR-4683	CLIP-seq
MIRT960129	hsa-miR-4685-3p	CLIP-seq
MIRT960130	hsa-miR-4685-5p	CLIP-seq
MIRT960131	hsa-miR-4688	CLIP-seq
MIRT960132	hsa-miR-4692	CLIP-seq
MIRT960133	hsa-miR-4708-3p	CLIP-seq
MIRT960134	hsa-miR-4722-5p	CLIP-seq
MIRT960135	hsa-miR-4725-3p	CLIP-seq
MIRT960136	hsa-miR-4731-3p	CLIP-seq
MIRT960137	hsa-miR-4731-5p	CLIP-seq
MIRT960138	hsa-miR-4733-3p	CLIP-seq
MIRT960139	hsa-miR-4736	CLIP-seq
MIRT960140	hsa-miR-4739	CLIP-seq
MIRT960141	hsa-miR-4742-5p	CLIP-seq
MIRT960142	hsa-miR-4755-5p	CLIP-seq
MIRT960143	hsa-miR-4756-5p	CLIP-seq
MIRT960144	hsa-miR-4761-5p	CLIP-seq
MIRT960145	hsa-miR-4763-3p	CLIP-seq
MIRT960146	hsa-miR-4770	CLIP-seq
MIRT960147	hsa-miR-4778-3p	CLIP-seq
MIRT960148	hsa-miR-4779	CLIP-seq
MIRT960149	hsa-miR-4784	CLIP-seq
MIRT960150	hsa-miR-4796-3p	CLIP-seq
MIRT960151	hsa-miR-4801	CLIP-seq
MIRT960152	hsa-miR-486-3p	CLIP-seq
MIRT960153	hsa-miR-489	CLIP-seq
MIRT960154	hsa-miR-506	CLIP-seq
MIRT960155	hsa-miR-508-5p	CLIP-seq
MIRT960156	hsa-miR-542-5p	CLIP-seq
MIRT960157	hsa-miR-545	CLIP-seq
MIRT960158	hsa-miR-548al	CLIP-seq
MIRT960159	hsa-miR-603	CLIP-seq
MIRT960160	hsa-miR-608	CLIP-seq
MIRT960161	hsa-miR-617	CLIP-seq
MIRT960162	hsa-miR-623	CLIP-seq
MIRT960163	hsa-miR-642a	CLIP-seq
MIRT960164	hsa-miR-650	CLIP-seq
MIRT960165	hsa-miR-665	CLIP-seq
MIRT960166	hsa-miR-765	CLIP-seq
MIRT960167	hsa-miR-874	CLIP-seq
MIRT960168	hsa-miR-875-3p	CLIP-seq
MIRT960169	hsa-miR-943	CLIP-seq
MIRT960170	hsa-miR-98	CLIP-seq
MIRT960032	hsa-let-7a	CLIP-seq
MIRT960033	hsa-let-7b	CLIP-seq
MIRT960034	hsa-let-7c	CLIP-seq
MIRT960035	hsa-let-7d	CLIP-seq
MIRT960036	hsa-let-7e	CLIP-seq
MIRT960037	hsa-let-7f	CLIP-seq
MIRT960038	hsa-let-7g	CLIP-seq
MIRT960039	hsa-let-7i	CLIP-seq
MIRT960042	hsa-miR-1207-5p	CLIP-seq
MIRT960047	hsa-miR-1253	CLIP-seq
MIRT960052	hsa-miR-1321	CLIP-seq
MIRT960057	hsa-miR-186	CLIP-seq
MIRT960060	hsa-miR-196a	CLIP-seq
MIRT960061	hsa-miR-196b	CLIP-seq
MIRT960067	hsa-miR-23a	CLIP-seq
MIRT960068	hsa-miR-23b	CLIP-seq
MIRT960069	hsa-miR-23c	CLIP-seq
MIRT960074	hsa-miR-3133	CLIP-seq
MIRT960078	hsa-miR-3154	CLIP-seq
MIRT960080	hsa-miR-3157-3p	CLIP-seq
MIRT960083	hsa-miR-3185	CLIP-seq
MIRT960085	hsa-miR-329	CLIP-seq
MIRT960087	hsa-miR-3612	CLIP-seq
MIRT960088	hsa-miR-3614-3p	CLIP-seq
MIRT960089	hsa-miR-362-3p	CLIP-seq
MIRT960093	hsa-miR-371-5p	CLIP-seq
MIRT960171	hsa-miR-3927	CLIP-seq
MIRT960097	hsa-miR-3941	CLIP-seq
MIRT960101	hsa-miR-4270	CLIP-seq
MIRT960104	hsa-miR-4290	CLIP-seq
MIRT960107	hsa-miR-4419a	CLIP-seq
MIRT960109	hsa-miR-4434	CLIP-seq
MIRT960110	hsa-miR-4441	CLIP-seq
MIRT960111	hsa-miR-4458	CLIP-seq
MIRT960112	hsa-miR-4459	CLIP-seq
MIRT960116	hsa-miR-4500	CLIP-seq
MIRT960118	hsa-miR-4510	CLIP-seq
MIRT960120	hsa-miR-4516	CLIP-seq
MIRT960172	hsa-miR-4650-3p	CLIP-seq
MIRT960124	hsa-miR-4662a-3p	CLIP-seq
MIRT960130	hsa-miR-4685-5p	CLIP-seq
MIRT960134	hsa-miR-4722-5p	CLIP-seq
MIRT960136	hsa-miR-4731-3p	CLIP-seq
MIRT960139	hsa-miR-4736	CLIP-seq
MIRT960140	hsa-miR-4739	CLIP-seq
MIRT960143	hsa-miR-4756-5p	CLIP-seq
MIRT960145	hsa-miR-4763-3p	CLIP-seq
MIRT960148	hsa-miR-4779	CLIP-seq
MIRT960151	hsa-miR-4801	CLIP-seq
MIRT960152	hsa-miR-486-3p	CLIP-seq
MIRT960159	hsa-miR-603	CLIP-seq
MIRT960164	hsa-miR-650	CLIP-seq
MIRT960167	hsa-miR-874	CLIP-seq
MIRT960170	hsa-miR-98	CLIP-seq
MIRT960042	hsa-miR-1207-5p	CLIP-seq
MIRT960046	hsa-miR-1252	CLIP-seq
MIRT960047	hsa-miR-1253	CLIP-seq
MIRT960050	hsa-miR-128	CLIP-seq
MIRT960052	hsa-miR-1321	CLIP-seq
MIRT960057	hsa-miR-186	CLIP-seq
MIRT1984405	hsa-miR-205	CLIP-seq
MIRT960071	hsa-miR-3119	CLIP-seq
MIRT960073	hsa-miR-3123	CLIP-seq
MIRT960074	hsa-miR-3133	CLIP-seq
MIRT960075	hsa-miR-3135	CLIP-seq
MIRT960077	hsa-miR-3150b-3p	CLIP-seq
MIRT960078	hsa-miR-3154	CLIP-seq
MIRT960080	hsa-miR-3157-3p	CLIP-seq
MIRT960083	hsa-miR-3185	CLIP-seq
MIRT1984406	hsa-miR-330-3p	CLIP-seq
MIRT960087	hsa-miR-3612	CLIP-seq
MIRT960088	hsa-miR-3614-3p	CLIP-seq
MIRT960093	hsa-miR-371-5p	CLIP-seq
MIRT960094	hsa-miR-371b-3p	CLIP-seq
MIRT960101	hsa-miR-4270	CLIP-seq
MIRT960104	hsa-miR-4290	CLIP-seq
MIRT1984407	hsa-miR-4291	CLIP-seq
MIRT960107	hsa-miR-4419a	CLIP-seq
MIRT960109	hsa-miR-4434	CLIP-seq
MIRT960110	hsa-miR-4441	CLIP-seq
MIRT960112	hsa-miR-4459	CLIP-seq
MIRT960118	hsa-miR-4510	CLIP-seq
MIRT960120	hsa-miR-4516	CLIP-seq
MIRT960122	hsa-miR-4645-5p	CLIP-seq
MIRT960123	hsa-miR-4651	CLIP-seq
MIRT960127	hsa-miR-4673	CLIP-seq
MIRT960128	hsa-miR-4683	CLIP-seq
MIRT960130	hsa-miR-4685-5p	CLIP-seq
MIRT960134	hsa-miR-4722-5p	CLIP-seq
MIRT1984408	hsa-miR-4725-5p	CLIP-seq
MIRT960139	hsa-miR-4736	CLIP-seq
MIRT960140	hsa-miR-4739	CLIP-seq
MIRT960141	hsa-miR-4742-5p	CLIP-seq
MIRT960143	hsa-miR-4756-5p	CLIP-seq
MIRT960145	hsa-miR-4763-3p	CLIP-seq
MIRT960148	hsa-miR-4779	CLIP-seq
MIRT960149	hsa-miR-4784	CLIP-seq
MIRT960150	hsa-miR-4796-3p	CLIP-seq
MIRT1984409	hsa-miR-4799-5p	CLIP-seq
MIRT960152	hsa-miR-486-3p	CLIP-seq
MIRT1984410	hsa-miR-500a	CLIP-seq
MIRT1984411	hsa-miR-504	CLIP-seq
MIRT960157	hsa-miR-545	CLIP-seq
MIRT1984412	hsa-miR-563	CLIP-seq
MIRT1984413	hsa-miR-605	CLIP-seq
MIRT960160	hsa-miR-608	CLIP-seq
MIRT960164	hsa-miR-650	CLIP-seq
MIRT960166	hsa-miR-765	CLIP-seq
MIRT960167	hsa-miR-874	CLIP-seq
MIRT960047	hsa-miR-1253	CLIP-seq
MIRT960050	hsa-miR-128	CLIP-seq
MIRT2219511	hsa-miR-339-5p	CLIP-seq
MIRT960094	hsa-miR-371b-3p	CLIP-seq
MIRT960171	hsa-miR-3927	CLIP-seq
MIRT2219512	hsa-miR-507	CLIP-seq
MIRT960157	hsa-miR-545	CLIP-seq
MIRT2219513	hsa-miR-557	CLIP-seq
MIRT960080	hsa-miR-3157-3p	CLIP-seq
MIRT960088	hsa-miR-3614-3p	CLIP-seq
MIRT960093	hsa-miR-371-5p	CLIP-seq
MIRT960096	hsa-miR-3929	CLIP-seq
MIRT960104	hsa-miR-4290	CLIP-seq
MIRT960107	hsa-miR-4419a	CLIP-seq
MIRT960108	hsa-miR-4419b	CLIP-seq
MIRT960114	hsa-miR-4478	CLIP-seq
MIRT960118	hsa-miR-4510	CLIP-seq
MIRT960167	hsa-miR-874	CLIP-seq
MIRT960042	hsa-miR-1207-5p	CLIP-seq
MIRT960080	hsa-miR-3157-3p	CLIP-seq
MIRT960088	hsa-miR-3614-3p	CLIP-seq
MIRT960093	hsa-miR-371-5p	CLIP-seq
MIRT960104	hsa-miR-4290	CLIP-seq
MIRT960139	hsa-miR-4736	CLIP-seq
MIRT960145	hsa-miR-4763-3p	CLIP-seq
MIRT960167	hsa-miR-874	CLIP-seq
MIRT960042	hsa-miR-1207-5p	CLIP-seq
MIRT960050	hsa-miR-128	CLIP-seq
MIRT960052	hsa-miR-1321	CLIP-seq
MIRT960057	hsa-miR-186	CLIP-seq
MIRT960074	hsa-miR-3133	CLIP-seq
MIRT960080	hsa-miR-3157-3p	CLIP-seq
MIRT960087	hsa-miR-3612	CLIP-seq
MIRT960088	hsa-miR-3614-3p	CLIP-seq
MIRT960093	hsa-miR-371-5p	CLIP-seq
MIRT960094	hsa-miR-371b-3p	CLIP-seq
MIRT960101	hsa-miR-4270	CLIP-seq
MIRT960104	hsa-miR-4290	CLIP-seq
MIRT960107	hsa-miR-4419a	CLIP-seq
MIRT960110	hsa-miR-4441	CLIP-seq
MIRT960112	hsa-miR-4459	CLIP-seq
MIRT960118	hsa-miR-4510	CLIP-seq
MIRT960130	hsa-miR-4685-5p	CLIP-seq
MIRT960134	hsa-miR-4722-5p	CLIP-seq
MIRT960139	hsa-miR-4736	CLIP-seq
MIRT960140	hsa-miR-4739	CLIP-seq
MIRT960143	hsa-miR-4756-5p	CLIP-seq
MIRT960145	hsa-miR-4763-3p	CLIP-seq
MIRT960148	hsa-miR-4779	CLIP-seq
MIRT960152	hsa-miR-486-3p	CLIP-seq
MIRT960164	hsa-miR-650	CLIP-seq
MIRT960167	hsa-miR-874	CLIP-seq
MIRT2679896	hsa-miR-1207-3p	CLIP-seq
MIRT960042	hsa-miR-1207-5p	CLIP-seq
MIRT960050	hsa-miR-128	CLIP-seq
MIRT960052	hsa-miR-1321	CLIP-seq
MIRT960057	hsa-miR-186	CLIP-seq
MIRT960074	hsa-miR-3133	CLIP-seq
MIRT2679897	hsa-miR-3148	CLIP-seq
MIRT960077	hsa-miR-3150b-3p	CLIP-seq
MIRT960078	hsa-miR-3154	CLIP-seq
MIRT960080	hsa-miR-3157-3p	CLIP-seq
MIRT2679898	hsa-miR-335	CLIP-seq
MIRT960087	hsa-miR-3612	CLIP-seq
MIRT2679899	hsa-miR-3613-3p	CLIP-seq
MIRT960088	hsa-miR-3614-3p	CLIP-seq
MIRT960093	hsa-miR-371-5p	CLIP-seq
MIRT960094	hsa-miR-371b-3p	CLIP-seq
MIRT960101	hsa-miR-4270	CLIP-seq
MIRT960104	hsa-miR-4290	CLIP-seq
MIRT960107	hsa-miR-4419a	CLIP-seq
MIRT960110	hsa-miR-4441	CLIP-seq
MIRT960112	hsa-miR-4459	CLIP-seq
MIRT960118	hsa-miR-4510	CLIP-seq
MIRT960128	hsa-miR-4683	CLIP-seq
MIRT960130	hsa-miR-4685-5p	CLIP-seq
MIRT960134	hsa-miR-4722-5p	CLIP-seq
MIRT960139	hsa-miR-4736	CLIP-seq
MIRT960140	hsa-miR-4739	CLIP-seq
MIRT960143	hsa-miR-4756-5p	CLIP-seq
MIRT960145	hsa-miR-4763-3p	CLIP-seq
MIRT960148	hsa-miR-4779	CLIP-seq
MIRT960149	hsa-miR-4784	CLIP-seq
MIRT960152	hsa-miR-486-3p	CLIP-seq
MIRT2679900	hsa-miR-548a-5p	CLIP-seq
MIRT2679901	hsa-miR-548ab	CLIP-seq
MIRT2679902	hsa-miR-548ak	CLIP-seq
MIRT2679903	hsa-miR-548b-5p	CLIP-seq
MIRT2679904	hsa-miR-548c-5p	CLIP-seq
MIRT2679905	hsa-miR-548d-5p	CLIP-seq
MIRT2679906	hsa-miR-548h	CLIP-seq
MIRT2679907	hsa-miR-548i	CLIP-seq
MIRT2679908	hsa-miR-548j	CLIP-seq
MIRT2679909	hsa-miR-548n	CLIP-seq
MIRT2679910	hsa-miR-548w	CLIP-seq
MIRT2679911	hsa-miR-548y	CLIP-seq
MIRT2679912	hsa-miR-559	CLIP-seq
MIRT960164	hsa-miR-650	CLIP-seq
MIRT960166	hsa-miR-765	CLIP-seq
MIRT960167	hsa-miR-874	CLIP-seq
MIRT960168	hsa-miR-875-3p	CLIP-seq

Show/Hide all (3)

Transcription factor	Regulation	Reference
NPM1	Unknown	23393136
SP1	Activation	15907486
TP53	Unknown	20805247

Show/Hide all (36)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	14625302
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	14625302
GO:0001787	Process	Natural killer cell proliferation	IEA
GO:0001787	Process	Natural killer cell proliferation	ISS
GO:0001866	Process	NK T cell proliferation	IEA
GO:0001866	Process	NK T cell proliferation	ISS
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	10207087, 14970218, 14976184
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0016605	Component	PML body	IDA	14970218
GO:0016605	Component	PML body	IEA
GO:0030154	Process	Cell differentiation	IBA
GO:0032691	Process	Negative regulation of interleukin-1 beta production	IEA
GO:0032691	Process	Negative regulation of interleukin-1 beta production	IMP	34326534
GO:0032715	Process	Negative regulation of interleukin-6 production	IEA
GO:0032715	Process	Negative regulation of interleukin-6 production	IMP	34326534
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IEA
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IMP	35266071
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	8895518, 9524226, 14625302
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	8895518, 9524226, 14625302, 14970218
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0050728	Process	Negative regulation of inflammatory response	IEA
GO:0050728	Process	Negative regulation of inflammatory response	IMP	34326534
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
300775	3319	ENSG00000102034

Q99607

Protein name

ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor)

Protein function

Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to tran

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12310	Elf-1_N	2 → 104	Transcription factor protein N terminal	Family
PF00178	Ets	210 → 291	Ets-domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Abundantly expressed in the placenta and in a variety of myeloid leukemia cell lines. Moderate levels of expression in heart, lung, spleen, thymus, peripheral blood lymphocytes, ovary and colon. Lower levels of expression in Jurkat T-c

Sequence

MAITLQPSDLIFEFASNGMDDDIHQLEDPSVFPAVIVEQVPYPDLLHLYSGLELDDVHNG
IITDGTLCMTQDQILEGSFLLTDDNEATSHTMSTAEVLLNMESPSDILDEKQIFSTSEML
PDSDPAPAVTLPNYLFPASEPDALNRAGDTSDQEGHSLEEKASREESAKKTGKSKKRIRK
TKGNRSTSPVTDPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFK
LVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVI
EDEDESSEATAAPPQASTASVASASTTRRTSSRVSSRSAPQGKGSSSWEKPKIQHVGLQP
SASLELGPSLDEEIPTTSTMLVSPAEGQVKLTKAVSASSVPSNIHLGVAPVGSGSALTLQ
TIPLTTVLTNGPPASTTAPTQLVLQSVPAASTFKDTFTLQASFPLNASFQDSQVAAPGAP
LILSGLPQLLAGANRPTNPAPPTVTGAGPAGPSSQPPGTVIAAFIRTSGTTAAPRVKEGP
LRSSSYVQGMVTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLS
PPSRPTVGLTPVAELELSSGSGSLLMAEPSVTTSGSLLTRSPTPAPFSPFNPTSLIKMEP
HDI

Sequence length

663

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Acute myeloid leukemia	Pathogenic	rs137884184	RCV005931786	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Autoinflammatory syndrome, familial, X-linked, Behcet-like 2	Pathogenic	rs2124614205, rs2124612467, rs2124614270	RCV002221446 RCV002221447 RCV002221448	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DENTAL CARIES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ELF4-related disorder	Likely benign; Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED AGAMMAGLOBULINEMIA WITH GROWTH HORMONE DEFICIENCY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED IMMUNE DYSREGULATION WITH INFLAMMATORY BOWEL DISEASE DUE TO ELF4 DEFICIENCY	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (36)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute Erythroblastic Leukemia	Erythroblastic Leukemia	BEFREE	12771947		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	28069875		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	19457610	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	32170761	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	36158120	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	36923538	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Delirium	Delirium	Pubtator	29991314	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	BEFREE	24185615		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelioma	Epithelioma	BEFREE	26921333		★★★★★ ★☆☆☆☆ Found in Text Mining only
Familial Mediterranean Fever	Familial mediterranean fever	Pubtator	9152834	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	23217424, 28069875		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	35862252	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	23217424, 28069875		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	23217424		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	35862252	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hematopoietic Neoplasms	Hematopoietic Neoplasms	BEFREE	26921333		★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory bowel disease	Pubtator	38231408	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Promyelocytic Acute	Promyelocytic leukemia	Pubtator	12893766	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	12620289, 16303180		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus Systemic	Systemic lupus erythematosus	Pubtator	34084162	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	30403914		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	20814243		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	28069875		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	12438253, 16303180, 19380490, 20814243, 27932483, 31085244		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	10223569		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple sclerosis	Pubtator	35905688	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasal Type Extranodal NK/T-Cell Lymphoma	Extranodal NK T Cell Lymphoma	BEFREE	21329961		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12438253, 26921333, 29706956		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	31624087		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	31624087	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurofibromatosis 2	Neurofibromatosis	BEFREE	30135214		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	37671970	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	30112966		★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinoblastoma	Retinoblastoma	BEFREE	23471649		★★★★★ ★☆☆☆☆ Found in Text Mining only
Teratoma	Teratoma	BEFREE	26598518		★★★★★ ★☆☆☆☆ Found in Text Mining only
X-linked agammaglobulinemia with growth hormone deficiency	Agammaglobulinemia With Growth Hormone Deficiency, X-Linked	ORPHANET_DG	18180883		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

ELF4 (E74 like ETS transcription factor 4)