Gene Gene information from NCBI Gene database.
Entrez ID 1955
Gene name Multiple EGF like domains 9
Gene symbol MEGF9
Synonyms (NCBI Gene)
EGFL5
Chromosome 9
Chromosome location 9q33.2
miRNA miRNA information provided by mirtarbase database.
1047
miRTarBase ID miRNA Experiments Reference
MIRT019118 hsa-miR-335-5p Microarray 18185580
MIRT019512 hsa-miR-151a-3p Sequencing 20371350
MIRT031063 hsa-miR-21-5p Microarray 18591254
MIRT048112 hsa-miR-197-3p CLASH 23622248
MIRT037264 hsa-miR-877-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
GO ID Ontology Definition Evidence Reference
GO:0005604 Component Basement membrane IEA
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604268 3234 ENSG00000106780
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H1U4
Protein name Multiple epidermal growth factor-like domains protein 9 (Multiple EGF-like domains protein 9) (Epidermal growth factor-like protein 5) (EGF-like protein 5)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00053 Laminin_EGF 204 251 Laminin EGF domain Domain
PF00053 Laminin_EGF 254 298 Laminin EGF domain Domain
PF00053 Laminin_EGF 301 346 Laminin EGF domain Domain
PF00053 Laminin_EGF 349 399 Laminin EGF domain Domain
PF00053 Laminin_EGF 400 449 Laminin EGF domain Domain
Sequence
MNGGAERAMRSLPSLGGLALLCCAAAAAAAAVASAASAGNVTGGGGAAGQVDASPGPGLR
GEPSHPFPRATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPL
GPSPTTPPAAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSS
SNSSVLPTPPATEAPSSPPPEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKE
GFYLNYTSGLC
QPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLP
CQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSC
SIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRK
CQCHGHVDPVKTPKICKPESG
ECINCLHNTTGFWCENCLEGYVHDLEGNC
IKKEVILPTPEGSTILVSNASLTTSVPTPVI
NSTFTPTTLQTIFSVSTSENSTSALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYRE
YQNRKLNAPFWTIELKEDNISFSSYHDSIPNADVSGLLEDDGNEVAPNGQLTLTTPIHNY
KA
Sequence length 602
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CHRONIC CENTRAL SEROUS RETINOPATHY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LUNG CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Breast Carcinoma Breast Carcinoma BEFREE 24098452
★☆☆☆☆
Found in Text Mining only
Breast Neoplasms Breast neoplasm Pubtator 24098452 Associate
★☆☆☆☆
Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome Hereditary breast and ovarian cancer syndrome Pubtator 24098452 Associate
★☆☆☆☆
Found in Text Mining only
Leukemia, Myelocytic, Acute Leukemia GWASCAT_DG 27903959
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of breast Breast Cancer BEFREE 24098452
★☆☆☆☆
Found in Text Mining only
Multiple Myeloma Multiple myeloma Pubtator 24816239 Associate
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 24098452
★☆☆☆☆
Found in Text Mining only
Neutropenia Neutropenia Pubtator 39208548 Associate
★☆☆☆☆
Found in Text Mining only
Scleroderma Systemic Systemic sclerosis Pubtator 39208548 Associate
★☆☆☆☆
Found in Text Mining only