EEF2 (eukaryotic translation elongation factor 2)

Gene

• Entrez ID: 1938
• Gene name: Eukaryotic translation elongation factor 2
• Gene symbol: EEF2
• Synonyms (NCBI Gene): EEF-2, EF-2, EF2, SCA26
• Chromosome: 19
• Chromosome location: 19p13.3
• Summary: This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ri

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs587777052	G>T	Pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT031753	hsa-miR-16-5p	Proteomics	18668040
MIRT052441	hsa-let-7a-5p	CLASH	23622248
MIRT051895	hsa-let-7b-5p	CLASH	23622248
MIRT051895	hsa-let-7b-5p	CLASH	23622248
MIRT051895	hsa-let-7b-5p	CLASH	23622248
MIRT050660	hsa-miR-18a-5p	CLASH	23622248
MIRT049963	hsa-miR-30a-5p	CLASH	23622248
MIRT049005	hsa-miR-92a-3p	CLASH	23622248
MIRT049005	hsa-miR-92a-3p	CLASH	23622248
MIRT049005	hsa-miR-92a-3p	CLASH	23622248
MIRT048271	hsa-miR-196a-5p	CLASH	23622248
MIRT047726	hsa-miR-10a-5p	CLASH	23622248
MIRT046806	hsa-miR-222-3p	CLASH	23622248
MIRT045338	hsa-miR-185-5p	CLASH	23622248
MIRT045161	hsa-miR-186-5p	CLASH	23622248
MIRT044535	hsa-miR-320a	CLASH	23622248
MIRT044210	hsa-miR-99b-5p	CLASH	23622248
MIRT043730	hsa-miR-342-3p	CLASH	23622248
MIRT042856	hsa-miR-324-3p	CLASH	23622248
MIRT042856	hsa-miR-324-3p	CLASH	23622248
MIRT041660	hsa-miR-484	CLASH	23622248
MIRT041660	hsa-miR-484	CLASH	23622248
MIRT041660	hsa-miR-484	CLASH	23622248
MIRT041660	hsa-miR-484	CLASH	23622248
MIRT041593	hsa-miR-193b-3p	CLASH	23622248
MIRT040505	hsa-miR-589-3p	CLASH	23622248
MIRT039659	hsa-miR-615-3p	CLASH	23622248
MIRT039659	hsa-miR-615-3p	CLASH	23622248
MIRT039659	hsa-miR-615-3p	CLASH	23622248
MIRT039659	hsa-miR-615-3p	CLASH	23622248
MIRT039112	hsa-miR-769-3p	CLASH	23622248
MIRT038923	hsa-miR-92a-1-5p	CLASH	23622248
MIRT038532	hsa-miR-99b-3p	CLASH	23622248
MIRT038365	hsa-miR-296-3p	CLASH	23622248
MIRT036266	hsa-miR-1229-3p	CLASH	23622248
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT502552	hsa-miR-5680	PAR-CLIP	20371350
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	20371350
MIRT502547	hsa-miR-3185	PAR-CLIP	20371350
MIRT502546	hsa-miR-3148	PAR-CLIP	20371350
MIRT502545	hsa-miR-6124	PAR-CLIP	20371350
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	20371350
MIRT502543	hsa-miR-4455	PAR-CLIP	20371350
MIRT502542	hsa-miR-609	PAR-CLIP	20371350
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	20371350
MIRT502540	hsa-miR-3657	PAR-CLIP	20371350
MIRT502539	hsa-miR-4425	PAR-CLIP	20371350
MIRT502538	hsa-miR-3147	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT502536	hsa-miR-1262	PAR-CLIP	20371350
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	20371350
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	20371350
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	20371350
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	20371350
MIRT562439	hsa-miR-155-5p	PAR-CLIP	20371350
MIRT562438	hsa-miR-4282	PAR-CLIP	20371350
MIRT562437	hsa-miR-3200-5p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT562436	hsa-miR-4682	PAR-CLIP	20371350
MIRT562435	hsa-miR-6854-3p	PAR-CLIP	20371350
MIRT562434	hsa-miR-8068	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT562433	hsa-miR-4520-3p	PAR-CLIP	20371350
MIRT562432	hsa-miR-2053	PAR-CLIP	20371350
MIRT511988	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT511987	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT562431	hsa-miR-4520-2-3p	PAR-CLIP	20371350
MIRT562430	hsa-miR-4529-3p	PAR-CLIP	20371350
MIRT511986	hsa-miR-4446-5p	PAR-CLIP	20371350
MIRT562429	hsa-miR-7850-5p	PAR-CLIP	20371350
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT502552	hsa-miR-5680	PAR-CLIP	20371350
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	20371350
MIRT502547	hsa-miR-3185	PAR-CLIP	20371350
MIRT502546	hsa-miR-3148	PAR-CLIP	20371350
MIRT502545	hsa-miR-6124	PAR-CLIP	20371350
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	20371350
MIRT502543	hsa-miR-4455	PAR-CLIP	20371350
MIRT502542	hsa-miR-609	PAR-CLIP	20371350
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	20371350
MIRT502540	hsa-miR-3657	PAR-CLIP	20371350
MIRT502539	hsa-miR-4425	PAR-CLIP	20371350
MIRT502538	hsa-miR-3147	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT502536	hsa-miR-1262	PAR-CLIP	20371350
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	20371350
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	20371350
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	20371350
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	20371350
MIRT562439	hsa-miR-155-5p	PAR-CLIP	20371350
MIRT562438	hsa-miR-4282	PAR-CLIP	20371350
MIRT562437	hsa-miR-3200-5p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT562436	hsa-miR-4682	PAR-CLIP	20371350
MIRT562435	hsa-miR-6854-3p	PAR-CLIP	20371350
MIRT562434	hsa-miR-8068	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT562433	hsa-miR-4520-3p	PAR-CLIP	20371350
MIRT562432	hsa-miR-2053	PAR-CLIP	20371350
MIRT511988	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT511987	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT562431	hsa-miR-4520-2-3p	PAR-CLIP	20371350
MIRT562430	hsa-miR-4529-3p	PAR-CLIP	20371350
MIRT511986	hsa-miR-4446-5p	PAR-CLIP	20371350
MIRT562429	hsa-miR-7850-5p	PAR-CLIP	20371350
MIRT548487	hsa-miR-514a-5p	PAR-CLIP	21572407
MIRT548486	hsa-miR-518c-5p	PAR-CLIP	21572407
MIRT548485	hsa-miR-875-3p	PAR-CLIP	21572407
MIRT548484	hsa-miR-6128	PAR-CLIP	21572407
MIRT548483	hsa-miR-4522	PAR-CLIP	21572407
MIRT548481	hsa-miR-5093	PAR-CLIP	21572407
MIRT548482	hsa-miR-1299	PAR-CLIP	21572407
MIRT548480	hsa-miR-488-3p	PAR-CLIP	21572407
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	23446348
MIRT502552	hsa-miR-5680	PAR-CLIP	23446348
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	23446348
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	23446348
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	23446348
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	23446348
MIRT502547	hsa-miR-3185	PAR-CLIP	23446348
MIRT502546	hsa-miR-3148	PAR-CLIP	23446348
MIRT502545	hsa-miR-6124	PAR-CLIP	23446348
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	23446348
MIRT502543	hsa-miR-4455	PAR-CLIP	23446348
MIRT502542	hsa-miR-609	PAR-CLIP	23446348
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	23446348
MIRT502540	hsa-miR-3657	PAR-CLIP	23446348
MIRT502539	hsa-miR-4425	PAR-CLIP	23446348
MIRT502538	hsa-miR-3147	PAR-CLIP	23446348
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	23446348
MIRT502536	hsa-miR-1262	PAR-CLIP	23446348
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	23446348
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	23446348
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	23446348
MIRT511988	hsa-miR-4755-5p	PAR-CLIP	23446348
MIRT511987	hsa-miR-5006-3p	PAR-CLIP	23446348
MIRT511986	hsa-miR-4446-5p	PAR-CLIP	23446348
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	24398324
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	24398324
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	24398324
MIRT502552	hsa-miR-5680	PAR-CLIP	24398324
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	24398324
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	24398324
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	24398324
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	24398324
MIRT502547	hsa-miR-3185	PAR-CLIP	24398324
MIRT502546	hsa-miR-3148	PAR-CLIP	24398324
MIRT502545	hsa-miR-6124	PAR-CLIP	24398324
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	24398324
MIRT502543	hsa-miR-4455	PAR-CLIP	24398324
MIRT502542	hsa-miR-609	PAR-CLIP	24398324
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	24398324
MIRT502540	hsa-miR-3657	PAR-CLIP	24398324
MIRT502539	hsa-miR-4425	PAR-CLIP	24398324
MIRT502538	hsa-miR-3147	PAR-CLIP	24398324
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	24398324
MIRT502536	hsa-miR-1262	PAR-CLIP	24398324
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	24398324
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	24398324
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	24398324
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	24398324
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT502552	hsa-miR-5680	PAR-CLIP	20371350
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	20371350
MIRT502547	hsa-miR-3185	PAR-CLIP	20371350
MIRT502546	hsa-miR-3148	PAR-CLIP	20371350
MIRT502545	hsa-miR-6124	PAR-CLIP	20371350
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	20371350
MIRT502543	hsa-miR-4455	PAR-CLIP	20371350
MIRT502542	hsa-miR-609	PAR-CLIP	20371350
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	20371350
MIRT502540	hsa-miR-3657	PAR-CLIP	20371350
MIRT502539	hsa-miR-4425	PAR-CLIP	20371350
MIRT502538	hsa-miR-3147	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT502536	hsa-miR-1262	PAR-CLIP	20371350
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	20371350
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	20371350
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	20371350
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	20371350
MIRT562439	hsa-miR-155-5p	PAR-CLIP	20371350
MIRT562438	hsa-miR-4282	PAR-CLIP	20371350
MIRT562437	hsa-miR-3200-5p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT562436	hsa-miR-4682	PAR-CLIP	20371350
MIRT562435	hsa-miR-6854-3p	PAR-CLIP	20371350
MIRT562434	hsa-miR-8068	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT562433	hsa-miR-4520-3p	PAR-CLIP	20371350
MIRT562432	hsa-miR-2053	PAR-CLIP	20371350
MIRT511988	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT511987	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT562431	hsa-miR-4520-2-3p	PAR-CLIP	20371350
MIRT562430	hsa-miR-4529-3p	PAR-CLIP	20371350
MIRT511986	hsa-miR-4446-5p	PAR-CLIP	20371350
MIRT562429	hsa-miR-7850-5p	PAR-CLIP	20371350
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT502552	hsa-miR-5680	PAR-CLIP	20371350
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	20371350
MIRT502547	hsa-miR-3185	PAR-CLIP	20371350
MIRT502546	hsa-miR-3148	PAR-CLIP	20371350
MIRT502545	hsa-miR-6124	PAR-CLIP	20371350
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	20371350
MIRT502543	hsa-miR-4455	PAR-CLIP	20371350
MIRT502542	hsa-miR-609	PAR-CLIP	20371350
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	20371350
MIRT502540	hsa-miR-3657	PAR-CLIP	20371350
MIRT502539	hsa-miR-4425	PAR-CLIP	20371350
MIRT502538	hsa-miR-3147	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT502536	hsa-miR-1262	PAR-CLIP	20371350
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	20371350
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	20371350
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	20371350
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	20371350
MIRT562439	hsa-miR-155-5p	PAR-CLIP	20371350
MIRT562438	hsa-miR-4282	PAR-CLIP	20371350
MIRT562437	hsa-miR-3200-5p	PAR-CLIP	20371350
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	20371350
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	20371350
MIRT562436	hsa-miR-4682	PAR-CLIP	20371350
MIRT562435	hsa-miR-6854-3p	PAR-CLIP	20371350
MIRT562434	hsa-miR-8068	PAR-CLIP	20371350
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	20371350
MIRT562433	hsa-miR-4520-3p	PAR-CLIP	20371350
MIRT562432	hsa-miR-2053	PAR-CLIP	20371350
MIRT511988	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT511987	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT562431	hsa-miR-4520-2-3p	PAR-CLIP	20371350
MIRT562430	hsa-miR-4529-3p	PAR-CLIP	20371350
MIRT511986	hsa-miR-4446-5p	PAR-CLIP	20371350
MIRT562429	hsa-miR-7850-5p	PAR-CLIP	20371350
MIRT548487	hsa-miR-514a-5p	PAR-CLIP	21572407
MIRT548486	hsa-miR-518c-5p	PAR-CLIP	21572407
MIRT548485	hsa-miR-875-3p	PAR-CLIP	21572407
MIRT548484	hsa-miR-6128	PAR-CLIP	21572407
MIRT548483	hsa-miR-4522	PAR-CLIP	21572407
MIRT548481	hsa-miR-5093	PAR-CLIP	21572407
MIRT548482	hsa-miR-1299	PAR-CLIP	21572407
MIRT548480	hsa-miR-488-3p	PAR-CLIP	21572407
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	23446348
MIRT502552	hsa-miR-5680	PAR-CLIP	23446348
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	23446348
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	23446348
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	23446348
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	23446348
MIRT502547	hsa-miR-3185	PAR-CLIP	23446348
MIRT502546	hsa-miR-3148	PAR-CLIP	23446348
MIRT502545	hsa-miR-6124	PAR-CLIP	23446348
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	23446348
MIRT502543	hsa-miR-4455	PAR-CLIP	23446348
MIRT502542	hsa-miR-609	PAR-CLIP	23446348
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	23446348
MIRT502540	hsa-miR-3657	PAR-CLIP	23446348
MIRT502539	hsa-miR-4425	PAR-CLIP	23446348
MIRT502538	hsa-miR-3147	PAR-CLIP	23446348
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	23446348
MIRT502536	hsa-miR-1262	PAR-CLIP	23446348
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	23446348
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	23446348
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	23446348
MIRT511988	hsa-miR-4755-5p	PAR-CLIP	23446348
MIRT511987	hsa-miR-5006-3p	PAR-CLIP	23446348
MIRT511986	hsa-miR-4446-5p	PAR-CLIP	23446348
MIRT502555	hsa-miR-548az-5p	PAR-CLIP	24398324
MIRT502554	hsa-miR-548t-5p	PAR-CLIP	24398324
MIRT502553	hsa-miR-4694-3p	PAR-CLIP	24398324
MIRT502552	hsa-miR-5680	PAR-CLIP	24398324
MIRT502551	hsa-miR-3688-3p	PAR-CLIP	24398324
MIRT502550	hsa-miR-6892-3p	PAR-CLIP	24398324
MIRT502549	hsa-miR-2276-5p	PAR-CLIP	24398324
MIRT502548	hsa-miR-146a-3p	PAR-CLIP	24398324
MIRT502547	hsa-miR-3185	PAR-CLIP	24398324
MIRT502546	hsa-miR-3148	PAR-CLIP	24398324
MIRT502545	hsa-miR-6124	PAR-CLIP	24398324
MIRT502544	hsa-miR-6772-5p	PAR-CLIP	24398324
MIRT502543	hsa-miR-4455	PAR-CLIP	24398324
MIRT502542	hsa-miR-609	PAR-CLIP	24398324
MIRT502541	hsa-miR-4433a-5p	PAR-CLIP	24398324
MIRT502540	hsa-miR-3657	PAR-CLIP	24398324
MIRT502539	hsa-miR-4425	PAR-CLIP	24398324
MIRT502538	hsa-miR-3147	PAR-CLIP	24398324
MIRT502537	hsa-miR-642a-5p	PAR-CLIP	24398324
MIRT502536	hsa-miR-1262	PAR-CLIP	24398324
MIRT502534	hsa-miR-4701-3p	PAR-CLIP	24398324
MIRT502535	hsa-miR-6736-5p	PAR-CLIP	24398324
MIRT502533	hsa-miR-6741-5p	PAR-CLIP	24398324
MIRT502532	hsa-miR-4433b-5p	PAR-CLIP	24398324
MIRT953142	hsa-miR-1207-3p	CLIP-seq
MIRT953143	hsa-miR-1266	CLIP-seq
MIRT953144	hsa-miR-1268	CLIP-seq
MIRT953145	hsa-miR-1268b	CLIP-seq
MIRT953146	hsa-miR-1281	CLIP-seq
MIRT953147	hsa-miR-1471	CLIP-seq
MIRT953148	hsa-miR-151-5p	CLIP-seq
MIRT953149	hsa-miR-151b	CLIP-seq
MIRT953150	hsa-miR-155	CLIP-seq
MIRT953151	hsa-miR-183	CLIP-seq
MIRT953152	hsa-miR-187	CLIP-seq
MIRT953153	hsa-miR-197	CLIP-seq
MIRT953154	hsa-miR-2114	CLIP-seq
MIRT953155	hsa-miR-296-5p	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953157	hsa-miR-3127-3p	CLIP-seq
MIRT953158	hsa-miR-3131	CLIP-seq
MIRT953159	hsa-miR-3135b	CLIP-seq
MIRT953160	hsa-miR-3162-3p	CLIP-seq
MIRT953161	hsa-miR-346	CLIP-seq
MIRT953162	hsa-miR-3679-3p	CLIP-seq
MIRT953163	hsa-miR-3687	CLIP-seq
MIRT953164	hsa-miR-3689d	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953166	hsa-miR-3923	CLIP-seq
MIRT953167	hsa-miR-3934	CLIP-seq
MIRT953168	hsa-miR-4251	CLIP-seq
MIRT953169	hsa-miR-4252	CLIP-seq
MIRT953170	hsa-miR-4258	CLIP-seq
MIRT953171	hsa-miR-4288	CLIP-seq
MIRT953172	hsa-miR-4314	CLIP-seq
MIRT953173	hsa-miR-4326	CLIP-seq
MIRT953174	hsa-miR-4329	CLIP-seq
MIRT953175	hsa-miR-4442	CLIP-seq
MIRT953176	hsa-miR-4520a-3p	CLIP-seq
MIRT953177	hsa-miR-4520b-3p	CLIP-seq
MIRT953178	hsa-miR-4658	CLIP-seq
MIRT953179	hsa-miR-4667-5p	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953181	hsa-miR-4700-5p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953183	hsa-miR-4734	CLIP-seq
MIRT953184	hsa-miR-4758-5p	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953186	hsa-miR-4765	CLIP-seq
MIRT953187	hsa-miR-4767	CLIP-seq
MIRT953188	hsa-miR-4795-3p	CLIP-seq
MIRT953189	hsa-miR-486-3p	CLIP-seq
MIRT953190	hsa-miR-488	CLIP-seq
MIRT953191	hsa-miR-548t	CLIP-seq
MIRT953192	hsa-miR-563	CLIP-seq
MIRT953193	hsa-miR-564	CLIP-seq
MIRT953194	hsa-miR-580	CLIP-seq
MIRT953195	hsa-miR-584	CLIP-seq
MIRT953196	hsa-miR-611	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953198	hsa-miR-632	CLIP-seq
MIRT953199	hsa-miR-637	CLIP-seq
MIRT953200	hsa-miR-642a	CLIP-seq
MIRT953201	hsa-miR-766	CLIP-seq
MIRT953202	hsa-miR-939	CLIP-seq
MIRT953142	hsa-miR-1207-3p	CLIP-seq
MIRT953143	hsa-miR-1266	CLIP-seq
MIRT953144	hsa-miR-1268	CLIP-seq
MIRT953145	hsa-miR-1268b	CLIP-seq
MIRT953146	hsa-miR-1281	CLIP-seq
MIRT953147	hsa-miR-1471	CLIP-seq
MIRT953148	hsa-miR-151-5p	CLIP-seq
MIRT953149	hsa-miR-151b	CLIP-seq
MIRT953150	hsa-miR-155	CLIP-seq
MIRT953151	hsa-miR-183	CLIP-seq
MIRT953152	hsa-miR-187	CLIP-seq
MIRT953155	hsa-miR-296-5p	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953157	hsa-miR-3127-3p	CLIP-seq
MIRT953158	hsa-miR-3131	CLIP-seq
MIRT953159	hsa-miR-3135b	CLIP-seq
MIRT953161	hsa-miR-346	CLIP-seq
MIRT953162	hsa-miR-3679-3p	CLIP-seq
MIRT953164	hsa-miR-3689d	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953166	hsa-miR-3923	CLIP-seq
MIRT953167	hsa-miR-3934	CLIP-seq
MIRT953168	hsa-miR-4251	CLIP-seq
MIRT953169	hsa-miR-4252	CLIP-seq
MIRT953170	hsa-miR-4258	CLIP-seq
MIRT953171	hsa-miR-4288	CLIP-seq
MIRT953172	hsa-miR-4314	CLIP-seq
MIRT953173	hsa-miR-4326	CLIP-seq
MIRT953174	hsa-miR-4329	CLIP-seq
MIRT953176	hsa-miR-4520a-3p	CLIP-seq
MIRT953177	hsa-miR-4520b-3p	CLIP-seq
MIRT953179	hsa-miR-4667-5p	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953181	hsa-miR-4700-5p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953183	hsa-miR-4734	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953187	hsa-miR-4767	CLIP-seq
MIRT953188	hsa-miR-4795-3p	CLIP-seq
MIRT953189	hsa-miR-486-3p	CLIP-seq
MIRT953191	hsa-miR-548t	CLIP-seq
MIRT953193	hsa-miR-564	CLIP-seq
MIRT953194	hsa-miR-580	CLIP-seq
MIRT953196	hsa-miR-611	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953198	hsa-miR-632	CLIP-seq
MIRT953199	hsa-miR-637	CLIP-seq
MIRT953200	hsa-miR-642a	CLIP-seq
MIRT953201	hsa-miR-766	CLIP-seq
MIRT953202	hsa-miR-939	CLIP-seq
MIRT953142	hsa-miR-1207-3p	CLIP-seq
MIRT953143	hsa-miR-1266	CLIP-seq
MIRT953144	hsa-miR-1268	CLIP-seq
MIRT953145	hsa-miR-1268b	CLIP-seq
MIRT953146	hsa-miR-1281	CLIP-seq
MIRT953147	hsa-miR-1471	CLIP-seq
MIRT953148	hsa-miR-151-5p	CLIP-seq
MIRT953149	hsa-miR-151b	CLIP-seq
MIRT953150	hsa-miR-155	CLIP-seq
MIRT953151	hsa-miR-183	CLIP-seq
MIRT953152	hsa-miR-187	CLIP-seq
MIRT953154	hsa-miR-2114	CLIP-seq
MIRT953155	hsa-miR-296-5p	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953157	hsa-miR-3127-3p	CLIP-seq
MIRT953158	hsa-miR-3131	CLIP-seq
MIRT953159	hsa-miR-3135b	CLIP-seq
MIRT953160	hsa-miR-3162-3p	CLIP-seq
MIRT953161	hsa-miR-346	CLIP-seq
MIRT953162	hsa-miR-3679-3p	CLIP-seq
MIRT953163	hsa-miR-3687	CLIP-seq
MIRT953164	hsa-miR-3689d	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953166	hsa-miR-3923	CLIP-seq
MIRT953167	hsa-miR-3934	CLIP-seq
MIRT953168	hsa-miR-4251	CLIP-seq
MIRT953169	hsa-miR-4252	CLIP-seq
MIRT953170	hsa-miR-4258	CLIP-seq
MIRT953171	hsa-miR-4288	CLIP-seq
MIRT953172	hsa-miR-4314	CLIP-seq
MIRT953173	hsa-miR-4326	CLIP-seq
MIRT953174	hsa-miR-4329	CLIP-seq
MIRT953175	hsa-miR-4442	CLIP-seq
MIRT953178	hsa-miR-4658	CLIP-seq
MIRT953179	hsa-miR-4667-5p	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953181	hsa-miR-4700-5p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953183	hsa-miR-4734	CLIP-seq
MIRT953184	hsa-miR-4758-5p	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953186	hsa-miR-4765	CLIP-seq
MIRT953187	hsa-miR-4767	CLIP-seq
MIRT953189	hsa-miR-486-3p	CLIP-seq
MIRT953190	hsa-miR-488	CLIP-seq
MIRT953191	hsa-miR-548t	CLIP-seq
MIRT953192	hsa-miR-563	CLIP-seq
MIRT953193	hsa-miR-564	CLIP-seq
MIRT953194	hsa-miR-580	CLIP-seq
MIRT953195	hsa-miR-584	CLIP-seq
MIRT953196	hsa-miR-611	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953198	hsa-miR-632	CLIP-seq
MIRT953199	hsa-miR-637	CLIP-seq
MIRT953201	hsa-miR-766	CLIP-seq
MIRT953202	hsa-miR-939	CLIP-seq
MIRT953142	hsa-miR-1207-3p	CLIP-seq
MIRT953144	hsa-miR-1268	CLIP-seq
MIRT953145	hsa-miR-1268b	CLIP-seq
MIRT953147	hsa-miR-1471	CLIP-seq
MIRT953148	hsa-miR-151-5p	CLIP-seq
MIRT953149	hsa-miR-151b	CLIP-seq
MIRT953152	hsa-miR-187	CLIP-seq
MIRT953154	hsa-miR-2114	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953157	hsa-miR-3127-3p	CLIP-seq
MIRT953158	hsa-miR-3131	CLIP-seq
MIRT953159	hsa-miR-3135b	CLIP-seq
MIRT953160	hsa-miR-3162-3p	CLIP-seq
MIRT953161	hsa-miR-346	CLIP-seq
MIRT953163	hsa-miR-3687	CLIP-seq
MIRT953164	hsa-miR-3689d	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953166	hsa-miR-3923	CLIP-seq
MIRT953167	hsa-miR-3934	CLIP-seq
MIRT953168	hsa-miR-4251	CLIP-seq
MIRT953171	hsa-miR-4288	CLIP-seq
MIRT953172	hsa-miR-4314	CLIP-seq
MIRT953174	hsa-miR-4329	CLIP-seq
MIRT953175	hsa-miR-4442	CLIP-seq
MIRT953178	hsa-miR-4658	CLIP-seq
MIRT953179	hsa-miR-4667-5p	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953181	hsa-miR-4700-5p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953184	hsa-miR-4758-5p	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953186	hsa-miR-4765	CLIP-seq
MIRT953189	hsa-miR-486-3p	CLIP-seq
MIRT953192	hsa-miR-563	CLIP-seq
MIRT953194	hsa-miR-580	CLIP-seq
MIRT953195	hsa-miR-584	CLIP-seq
MIRT953196	hsa-miR-611	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953198	hsa-miR-632	CLIP-seq
MIRT953199	hsa-miR-637	CLIP-seq
MIRT953201	hsa-miR-766	CLIP-seq
MIRT953142	hsa-miR-1207-3p	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953159	hsa-miR-3135b	CLIP-seq
MIRT953164	hsa-miR-3689d	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953166	hsa-miR-3923	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953143	hsa-miR-1266	CLIP-seq
MIRT953148	hsa-miR-151-5p	CLIP-seq
MIRT953149	hsa-miR-151b	CLIP-seq
MIRT953155	hsa-miR-296-5p	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953158	hsa-miR-3131	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953167	hsa-miR-3934	CLIP-seq
MIRT953168	hsa-miR-4251	CLIP-seq
MIRT953174	hsa-miR-4329	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953193	hsa-miR-564	CLIP-seq
MIRT953194	hsa-miR-580	CLIP-seq
MIRT953196	hsa-miR-611	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953201	hsa-miR-766	CLIP-seq
MIRT953202	hsa-miR-939	CLIP-seq
MIRT953143	hsa-miR-1266	CLIP-seq
MIRT953155	hsa-miR-296-5p	CLIP-seq
MIRT953193	hsa-miR-564	CLIP-seq
MIRT953202	hsa-miR-939	CLIP-seq
MIRT953142	hsa-miR-1207-3p	CLIP-seq
MIRT953143	hsa-miR-1266	CLIP-seq
MIRT953147	hsa-miR-1471	CLIP-seq
MIRT953150	hsa-miR-155	CLIP-seq
MIRT953151	hsa-miR-183	CLIP-seq
MIRT953155	hsa-miR-296-5p	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953157	hsa-miR-3127-3p	CLIP-seq
MIRT953159	hsa-miR-3135b	CLIP-seq
MIRT953162	hsa-miR-3679-3p	CLIP-seq
MIRT953164	hsa-miR-3689d	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953166	hsa-miR-3923	CLIP-seq
MIRT953167	hsa-miR-3934	CLIP-seq
MIRT953168	hsa-miR-4251	CLIP-seq
MIRT953169	hsa-miR-4252	CLIP-seq
MIRT953172	hsa-miR-4314	CLIP-seq
MIRT953173	hsa-miR-4326	CLIP-seq
MIRT953174	hsa-miR-4329	CLIP-seq
MIRT953176	hsa-miR-4520a-3p	CLIP-seq
MIRT953177	hsa-miR-4520b-3p	CLIP-seq
MIRT953178	hsa-miR-4658	CLIP-seq
MIRT953179	hsa-miR-4667-5p	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953181	hsa-miR-4700-5p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953183	hsa-miR-4734	CLIP-seq
MIRT953184	hsa-miR-4758-5p	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953186	hsa-miR-4765	CLIP-seq
MIRT953187	hsa-miR-4767	CLIP-seq
MIRT953189	hsa-miR-486-3p	CLIP-seq
MIRT953191	hsa-miR-548t	CLIP-seq
MIRT953192	hsa-miR-563	CLIP-seq
MIRT953193	hsa-miR-564	CLIP-seq
MIRT953194	hsa-miR-580	CLIP-seq
MIRT953195	hsa-miR-584	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953199	hsa-miR-637	CLIP-seq
MIRT953200	hsa-miR-642a	CLIP-seq
MIRT953201	hsa-miR-766	CLIP-seq
MIRT953202	hsa-miR-939	CLIP-seq
MIRT953143	hsa-miR-1266	CLIP-seq
MIRT953147	hsa-miR-1471	CLIP-seq
MIRT953148	hsa-miR-151-5p	CLIP-seq
MIRT953149	hsa-miR-151b	CLIP-seq
MIRT953150	hsa-miR-155	CLIP-seq
MIRT953155	hsa-miR-296-5p	CLIP-seq
MIRT953156	hsa-miR-3074-5p	CLIP-seq
MIRT953157	hsa-miR-3127-3p	CLIP-seq
MIRT953158	hsa-miR-3131	CLIP-seq
MIRT953162	hsa-miR-3679-3p	CLIP-seq
MIRT953165	hsa-miR-3907	CLIP-seq
MIRT953167	hsa-miR-3934	CLIP-seq
MIRT953168	hsa-miR-4251	CLIP-seq
MIRT953169	hsa-miR-4252	CLIP-seq
MIRT953172	hsa-miR-4314	CLIP-seq
MIRT953173	hsa-miR-4326	CLIP-seq
MIRT953174	hsa-miR-4329	CLIP-seq
MIRT953176	hsa-miR-4520a-3p	CLIP-seq
MIRT953177	hsa-miR-4520b-3p	CLIP-seq
MIRT953179	hsa-miR-4667-5p	CLIP-seq
MIRT953180	hsa-miR-4700-3p	CLIP-seq
MIRT953181	hsa-miR-4700-5p	CLIP-seq
MIRT953182	hsa-miR-4722-3p	CLIP-seq
MIRT953183	hsa-miR-4734	CLIP-seq
MIRT953185	hsa-miR-4763-5p	CLIP-seq
MIRT953187	hsa-miR-4767	CLIP-seq
MIRT953189	hsa-miR-486-3p	CLIP-seq
MIRT953191	hsa-miR-548t	CLIP-seq
MIRT953193	hsa-miR-564	CLIP-seq
MIRT953194	hsa-miR-580	CLIP-seq
MIRT953196	hsa-miR-611	CLIP-seq
MIRT953197	hsa-miR-617	CLIP-seq
MIRT953199	hsa-miR-637	CLIP-seq
MIRT953200	hsa-miR-642a	CLIP-seq
MIRT953201	hsa-miR-766	CLIP-seq
MIRT953202	hsa-miR-939	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002039	Function	P53 binding	IEA
GO:0002244	Process	Hematopoietic progenitor cell differentiation	IEA
GO:0002931	Process	Response to ischemia	IEA
GO:0003009	Process	Skeletal muscle contraction	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0003746	Function	Translation elongation factor activity	IBA
GO:0003746	Function	Translation elongation factor activity	IDA	26593721
GO:0003746	Function	Translation elongation factor activity	IEA
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IDA	26593721
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	19417104, 25064856, 25231979, 29128334, 32814053, 33961781
GO:0005525	Function	GTP binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	25064856
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005840	Component	Ribosome	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0006412	Process	Translation	IEA
GO:0006414	Process	Translational elongation	IBA
GO:0006414	Process	Translational elongation	IDA	26593721
GO:0006414	Process	Translational elongation	IEA
GO:0006414	Process	Translational elongation	IEA
GO:0008097	Function	5S rRNA binding	IEA
GO:0009410	Process	Response to xenobiotic stimulus	IEA
GO:0014009	Process	Glial cell proliferation	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016235	Component	Aggresome	IDA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019901	Function	Protein kinase binding	IPI	23823123
GO:0032355	Process	Response to estradiol	IEA
GO:0034774	Component	Secretory granule lumen	TAS
GO:0034976	Process	Response to endoplasmic reticulum stress	IEA
GO:0035914	Process	Skeletal muscle cell differentiation	IEA
GO:0042542	Process	Response to hydrogen peroxide	IEA
GO:0043022	Function	Ribosome binding	IBA
GO:0043022	Function	Ribosome binding	IDA	23636399
GO:0043022	Function	Ribosome binding	IEA
GO:0045202	Component	Synapse	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045471	Process	Response to ethanol	IEA
GO:0045727	Process	Positive regulation of translation	IEA
GO:0045727	Process	Positive regulation of translation	IMP	23184662
GO:0051015	Function	Actin filament binding	IEA
GO:0051593	Process	Response to folic acid	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 20458337, 23533145
GO:0098794	Component	Postsynapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0106222	Function	LncRNA binding	IEA
GO:0140242	Process	Translation at postsynapse	IEA
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS
GO:1990416	Process	Cellular response to brain-derived neurotrophic factor stimulus	IEA
GO:1990904	Component	Ribonucleoprotein complex	IBA
GO:1990904	Component	Ribonucleoprotein complex	IDA	18809582
GO:1990904	Component	Ribonucleoprotein complex	IEA
GO:2000767	Process	Positive regulation of cytoplasmic translation	IEA

Other IDs

• MIM: 130610
• HGNC: 3214
• e!Ensembl: ENSG00000167658

Protein

• UniProt ID: P13639
• Protein name: Elongation factor 2 (EF-2) (EC 3.6.5.-)
• Protein function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation (PubMed:26593721). During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-si
• PDB: 4V6X, 6D9J, 6Z6M, 6Z6N, 8UKB, 8XSX, 8Y0W, 8Y0X
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00009	GTP_EFTU	17 → 360	Elongation factor Tu GTP binding domain	Domain
  PF03144	GTP_EFTU_D2	409 → 486	Elongation factor Tu domain 2	Domain
  PF14492	EFG_III	501 → 568	Elongation Factor G, domain III	Domain
  PF03764	EFG_IV	620 → 737	Elongation factor G, domain IV	Domain
  PF00679	EFG_C	739 → 828	Elongation factor G C-terminus	Domain

• Sequence:

  MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTR
  KDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALR
  VTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQR
  IVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKG
  EGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKV
  FDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPS
  PVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGL
  VSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLV
  KTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEE
  SGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHN
  RLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPN
  ILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQ
  IIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTP
  MFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRK
  RKGLKEGIPALDNFLDKL

• Sequence length: 858

Pathways

KEGG:

AMPK signaling pathway
Oxytocin signaling pathway

Reactome:

Peptide chain elongation
Uptake and function of diphtheria toxin
Synthesis of diphthamide-EEF2
Neutrophil degranulation
Protein methylation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Spinocerebellar ataxia type 26	Likely pathogenic; Pathogenic	rs2145355764, rs587777052	RCV002267210 RCV000056312	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, RENAL CELL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EEF2-related disorder	Likely benign; Uncertain significance; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EEF2-related Neurodevelopmental disorder	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLAUCOMA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDER	—	GenCC	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPINOCEREBELLAR ATAXIA 19	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPINOCEREBELLAR ATAXIA 26	—	CTD, Disgenet, HPO CTD, Disgenet, HPO CTD, Disgenet, HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Spinocerebellar ataxia type 19/22	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	CTD_human_DG	21554491		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma, Basal Cell	Adenocarcinoma	CTD_human_DG	21554491		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma, Oxyphilic	Adenocarcinoma	CTD_human_DG	21554491		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma, Tubular	Adenocarcinoma	CTD_human_DG	21554491		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	26512942	Associate	★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	30450663		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	CTD_human_DG	20562527		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	16648488	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Burnett Schwartz Berberian syndrome	Burnett schwartz berberian syndrome	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	28060762	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	29342219		★☆☆☆☆ Found in Text Mining only
Carcinoma, Cribriform	Carcinoma	CTD_human_DG	21554491		★☆☆☆☆ Found in Text Mining only
Carcinoma, Granular Cell	Carcinoma	CTD_human_DG	21554491		★☆☆☆☆ Found in Text Mining only
Cardiomegaly	Cardiomegaly	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
Cardiomyopathy Dilated	Dilated cardiomyopathy	Pubtator	28427148	Associate	★☆☆☆☆ Found in Text Mining only
Cerebellar Ataxia	Cerebellar ataxia	Pubtator	33355653	Associate	★☆☆☆☆ Found in Text Mining only
Cerebellar atrophy	Cerebellar atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Chromophobe Renal Cell Carcinoma	Chromophobe Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Collecting Duct Carcinoma of the Kidney	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Coloboma	Coloboma	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	35445138	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	19360331		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	24589652	Stimulate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	28205128		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	CTD_human_DG	18784066		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	31488789		★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	33355653, 36470424, 37159414	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	30035378		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	30035378		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	30987676		★☆☆☆☆ Found in Text Mining only
Diffuse Intrinsic Pontine Glioma	Diffuse Intrinsic Pontine Glioma	BEFREE	24297113		★☆☆☆☆ Found in Text Mining only
Dysarthria	Dysarthria	HPO_DG			★☆☆☆☆ Found in Text Mining only
Dystrophia myotonica 2	Myotonic dystrophy	BEFREE	19605641		★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	36601599	Associate	★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	27005990		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	24589652	Stimulate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	25346520		★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	29342219	Associate	★☆☆☆☆ Found in Text Mining only
Hydrocephalus	Hydrocephalus	Pubtator	33355653, 37159414	Associate	★☆☆☆☆ Found in Text Mining only
Hypersensitivity Delayed	Hypersensitivity	Pubtator	33355653	Associate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	16648488	Inhibit	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
Intervertebral Disc Degeneration	Intervertebral Disc Degeneration	BEFREE	30987676		★☆☆☆☆ Found in Text Mining only
Intervertebral disc disorder	Intervertebral Disc Disorder	BEFREE	30987676		★☆☆☆☆ Found in Text Mining only
Language Development Disorders	Language development disorders	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	24363282, 28060762		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	CTD_human_DG	21554491		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung Neoplasms	Lung neoplasms	Pubtator	24589652	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphoma, Non-Hodgkin	Non-Hodgkin lymphoma	BEFREE	24589652		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	CTD_human_DG	20562527		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	CTD_human_DG	21554491		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	29342219		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	24589652, 28913610		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	31558304		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	22932089, 24589652		★☆☆☆☆ Found in Text Mining only
Mammary Carcinoma, Human	Marfan Syndrome	CTD_human_DG	20562527		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	16648488		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	CTD_human_DG	20562527		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms, Human	Mammary Neoplasms	CTD_human_DG	20562527		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	31488789		★☆☆☆☆ Found in Text Mining only
Microphthalmos	Microphthalmos	Pubtator	37159414	Associate	★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial Ischemia	BEFREE	28205128		★☆☆☆☆ Found in Text Mining only
Myotonic Dystrophy	Myotonic dystrophy	Pubtator	19605641	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	22911754, 28060762, 9823325		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	28574509		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	23001565		★☆☆☆☆ Found in Text Mining only
Nystagmus	Nystagmus	HPO_DG			★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	24480285, 32255771	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Osteoarthrosis Deformans	Osteoarthrosis Deformans	CTD_human_DG	18784066		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	24589652	Associate	★☆☆☆☆ Found in Text Mining only
Papillary Renal Cell Carcinoma	Papillary Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	26621506		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	26621506	Associate	★☆☆☆☆ Found in Text Mining only
Progressive cerebellar ataxia	Cerebellar Ataxia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Prostate cancer familial	Prostate cancer	Pubtator	24589652	Stimulate	★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	28913610		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	28913610	Associate	★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
Sarcomatoid Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	15108329		★☆☆☆☆ Found in Text Mining only
SPINOCEREBELLAR ATAXIA 26	Spinocerebellar Ataxia	ORPHANET_DG	23001565		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPINOCEREBELLAR ATAXIA 26	Spinocerebellar Ataxia	UNIPROT_DG	23001565		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Spinocerebellar ataxia 26	Spinocerebellar ataxia	Pubtator	33355653, 37159414	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPINOCEREBELLAR ATAXIA 26	Spinocerebellar Ataxia	CTD_human_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPINOCEREBELLAR ATAXIA 26	Spinocerebellar Ataxia	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Spinocerebellar ataxia type 26	Spinocerebellar Ataxia	Orphanet			★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	20497865, 24589652	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of lung	Lung carcinoma	BEFREE	27542262		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	31558304		★☆☆☆☆ Found in Text Mining only