Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	1750
Gene name	Distal-less homeobox 6
Gene symbol	DLX6
Synonyms (NCBI Gene)	-
Chromosome	7
Chromosome location	7q21.3
Summary	This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. This family is comprised of at least 6 different members that encode proteins with roles in forebrain and craniofacial development. This

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019311	hsa-miR-148b-3p	Microarray	17612493
MIRT049253	hsa-miR-92a-3p	CLASH	23622248
MIRT452367	hsa-miR-4428	PAR-CLIP	20371350
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	20371350
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	20371350
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	20371350
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT452361	hsa-miR-4419a	PAR-CLIP	20371350
MIRT452360	hsa-miR-4510	PAR-CLIP	20371350
MIRT452359	hsa-miR-6127	PAR-CLIP	20371350
MIRT452358	hsa-miR-6129	PAR-CLIP	20371350
MIRT452357	hsa-miR-6130	PAR-CLIP	20371350
MIRT452356	hsa-miR-6133	PAR-CLIP	20371350
MIRT452355	hsa-miR-185-5p	PAR-CLIP	20371350
MIRT452354	hsa-miR-4306	PAR-CLIP	20371350
MIRT452353	hsa-miR-4644	PAR-CLIP	20371350
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT452350	hsa-miR-8085	PAR-CLIP	20371350
MIRT452367	hsa-miR-4428	PAR-CLIP	22012620
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	22012620
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	22012620
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	22012620
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	22012620
MIRT452361	hsa-miR-4419a	PAR-CLIP	22012620
MIRT452360	hsa-miR-4510	PAR-CLIP	22012620
MIRT452359	hsa-miR-6127	PAR-CLIP	22012620
MIRT452358	hsa-miR-6129	PAR-CLIP	22012620
MIRT452357	hsa-miR-6130	PAR-CLIP	22012620
MIRT452356	hsa-miR-6133	PAR-CLIP	22012620
MIRT452355	hsa-miR-185-5p	PAR-CLIP	22012620
MIRT452354	hsa-miR-4306	PAR-CLIP	22012620
MIRT452353	hsa-miR-4644	PAR-CLIP	22012620
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	22012620
MIRT452350	hsa-miR-8085	PAR-CLIP	22012620
MIRT452351	hsa-miR-5739	PAR-CLIP	22012620
MIRT452367	hsa-miR-4428	PAR-CLIP	24398324
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	24398324
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	24398324
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	24398324
MIRT452361	hsa-miR-4419a	PAR-CLIP	24398324
MIRT452360	hsa-miR-4510	PAR-CLIP	24398324
MIRT452359	hsa-miR-6127	PAR-CLIP	24398324
MIRT452358	hsa-miR-6129	PAR-CLIP	24398324
MIRT452357	hsa-miR-6130	PAR-CLIP	24398324
MIRT452356	hsa-miR-6133	PAR-CLIP	24398324
MIRT452355	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT452354	hsa-miR-4306	PAR-CLIP	24398324
MIRT452353	hsa-miR-4644	PAR-CLIP	24398324
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT452350	hsa-miR-8085	PAR-CLIP	24398324
MIRT452351	hsa-miR-5739	PAR-CLIP	24398324
MIRT452367	hsa-miR-4428	PAR-CLIP	23592263
MIRT494114	hsa-miR-3123	PAR-CLIP	23592263
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452361	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452360	hsa-miR-4510	PAR-CLIP	23592263
MIRT452359	hsa-miR-6127	PAR-CLIP	23592263
MIRT452358	hsa-miR-6129	PAR-CLIP	23592263
MIRT452357	hsa-miR-6130	PAR-CLIP	23592263
MIRT452356	hsa-miR-6133	PAR-CLIP	23592263
MIRT452355	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT452354	hsa-miR-4306	PAR-CLIP	23592263
MIRT452353	hsa-miR-4644	PAR-CLIP	23592263
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT452350	hsa-miR-8085	PAR-CLIP	23592263
MIRT452351	hsa-miR-5739	PAR-CLIP	23592263
MIRT452367	hsa-miR-4428	PAR-CLIP	23592263
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452361	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452360	hsa-miR-4510	PAR-CLIP	23592263
MIRT452359	hsa-miR-6127	PAR-CLIP	23592263
MIRT452358	hsa-miR-6129	PAR-CLIP	23592263
MIRT452357	hsa-miR-6130	PAR-CLIP	23592263
MIRT452356	hsa-miR-6133	PAR-CLIP	23592263
MIRT452355	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT452354	hsa-miR-4306	PAR-CLIP	23592263
MIRT452353	hsa-miR-4644	PAR-CLIP	23592263
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT452350	hsa-miR-8085	PAR-CLIP	23592263
MIRT452351	hsa-miR-5739	PAR-CLIP	23592263
MIRT452367	hsa-miR-4428	PAR-CLIP	23592263
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452361	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452360	hsa-miR-4510	PAR-CLIP	23592263
MIRT452359	hsa-miR-6127	PAR-CLIP	23592263
MIRT452358	hsa-miR-6129	PAR-CLIP	23592263
MIRT452357	hsa-miR-6130	PAR-CLIP	23592263
MIRT452356	hsa-miR-6133	PAR-CLIP	23592263
MIRT452355	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT452354	hsa-miR-4306	PAR-CLIP	23592263
MIRT452353	hsa-miR-4644	PAR-CLIP	23592263
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT452350	hsa-miR-8085	PAR-CLIP	23592263
MIRT452351	hsa-miR-5739	PAR-CLIP	23592263
MIRT452355	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT452355	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT452355	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT452355	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT452354	hsa-miR-4306	PAR-CLIP	26701625
MIRT452354	hsa-miR-4306	PAR-CLIP	26701625
MIRT452354	hsa-miR-4306	PAR-CLIP	26701625
MIRT452354	hsa-miR-4306	PAR-CLIP	26701625
MIRT452361	hsa-miR-4419a	PAR-CLIP	26701625
MIRT452361	hsa-miR-4419a	PAR-CLIP	26701625
MIRT452361	hsa-miR-4419a	PAR-CLIP	26701625
MIRT452361	hsa-miR-4419a	PAR-CLIP	26701625
MIRT452367	hsa-miR-4428	PAR-CLIP	26701625
MIRT452367	hsa-miR-4428	PAR-CLIP	26701625
MIRT452367	hsa-miR-4428	PAR-CLIP	26701625
MIRT452367	hsa-miR-4428	PAR-CLIP	26701625
MIRT452360	hsa-miR-4510	PAR-CLIP	26701625
MIRT452360	hsa-miR-4510	PAR-CLIP	26701625
MIRT452360	hsa-miR-4510	PAR-CLIP	26701625
MIRT452360	hsa-miR-4510	PAR-CLIP	26701625
MIRT452353	hsa-miR-4644	PAR-CLIP	26701625
MIRT452353	hsa-miR-4644	PAR-CLIP	26701625
MIRT452353	hsa-miR-4644	PAR-CLIP	26701625
MIRT452353	hsa-miR-4644	PAR-CLIP	26701625
MIRT452351	hsa-miR-5739	PAR-CLIP	26701625
MIRT452351	hsa-miR-5739	PAR-CLIP	26701625
MIRT452351	hsa-miR-5739	PAR-CLIP	26701625
MIRT452351	hsa-miR-5739	PAR-CLIP	26701625
MIRT452359	hsa-miR-6127	PAR-CLIP	26701625
MIRT452359	hsa-miR-6127	PAR-CLIP	26701625
MIRT452359	hsa-miR-6127	PAR-CLIP	26701625
MIRT452359	hsa-miR-6127	PAR-CLIP	26701625
MIRT452358	hsa-miR-6129	PAR-CLIP	26701625
MIRT452358	hsa-miR-6129	PAR-CLIP	26701625
MIRT452358	hsa-miR-6129	PAR-CLIP	26701625
MIRT452358	hsa-miR-6129	PAR-CLIP	26701625
MIRT452357	hsa-miR-6130	PAR-CLIP	26701625
MIRT452357	hsa-miR-6130	PAR-CLIP	26701625
MIRT452357	hsa-miR-6130	PAR-CLIP	26701625
MIRT452357	hsa-miR-6130	PAR-CLIP	26701625
MIRT452356	hsa-miR-6133	PAR-CLIP	26701625
MIRT452356	hsa-miR-6133	PAR-CLIP	26701625
MIRT452356	hsa-miR-6133	PAR-CLIP	26701625
MIRT452356	hsa-miR-6133	PAR-CLIP	26701625
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	26701625
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	26701625
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	26701625
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	26701625
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	26701625
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	26701625
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	26701625
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	26701625
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	26701625
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	26701625
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	26701625
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	26701625
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	26701625
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	26701625
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	26701625
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	26701625
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	26701625
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	26701625
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	26701625
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	26701625
MIRT452350	hsa-miR-8085	PAR-CLIP	26701625
MIRT452350	hsa-miR-8085	PAR-CLIP	26701625
MIRT452350	hsa-miR-8085	PAR-CLIP	26701625
MIRT452350	hsa-miR-8085	PAR-CLIP	26701625
MIRT452355	hsa-miR-185-5p	PAR-CLIP	27292025
MIRT452355	hsa-miR-185-5p	PAR-CLIP	27292025
MIRT452355	hsa-miR-185-5p	PAR-CLIP	27292025
MIRT452355	hsa-miR-185-5p	PAR-CLIP	27292025
MIRT452355	hsa-miR-185-5p	PAR-CLIP	27292025
MIRT494114	hsa-miR-3123	PAR-CLIP	27292025
MIRT494114	hsa-miR-3123	PAR-CLIP	27292025
MIRT452354	hsa-miR-4306	PAR-CLIP	27292025
MIRT452354	hsa-miR-4306	PAR-CLIP	27292025
MIRT452354	hsa-miR-4306	PAR-CLIP	27292025
MIRT452354	hsa-miR-4306	PAR-CLIP	27292025
MIRT452354	hsa-miR-4306	PAR-CLIP	27292025
MIRT452361	hsa-miR-4419a	PAR-CLIP	27292025
MIRT452361	hsa-miR-4419a	PAR-CLIP	27292025
MIRT452361	hsa-miR-4419a	PAR-CLIP	27292025
MIRT452361	hsa-miR-4419a	PAR-CLIP	27292025
MIRT452361	hsa-miR-4419a	PAR-CLIP	27292025
MIRT452367	hsa-miR-4428	PAR-CLIP	27292025
MIRT452367	hsa-miR-4428	PAR-CLIP	27292025
MIRT452367	hsa-miR-4428	PAR-CLIP	27292025
MIRT452367	hsa-miR-4428	PAR-CLIP	27292025
MIRT452367	hsa-miR-4428	PAR-CLIP	27292025
MIRT452360	hsa-miR-4510	PAR-CLIP	27292025
MIRT452360	hsa-miR-4510	PAR-CLIP	27292025
MIRT452360	hsa-miR-4510	PAR-CLIP	27292025
MIRT452360	hsa-miR-4510	PAR-CLIP	27292025
MIRT452360	hsa-miR-4510	PAR-CLIP	27292025
MIRT452353	hsa-miR-4644	PAR-CLIP	27292025
MIRT452353	hsa-miR-4644	PAR-CLIP	27292025
MIRT452353	hsa-miR-4644	PAR-CLIP	27292025
MIRT452353	hsa-miR-4644	PAR-CLIP	27292025
MIRT452353	hsa-miR-4644	PAR-CLIP	27292025
MIRT452351	hsa-miR-5739	PAR-CLIP	27292025
MIRT452351	hsa-miR-5739	PAR-CLIP	27292025
MIRT452351	hsa-miR-5739	PAR-CLIP	27292025
MIRT452351	hsa-miR-5739	PAR-CLIP	27292025
MIRT452351	hsa-miR-5739	PAR-CLIP	27292025
MIRT452359	hsa-miR-6127	PAR-CLIP	27292025
MIRT452359	hsa-miR-6127	PAR-CLIP	27292025
MIRT452359	hsa-miR-6127	PAR-CLIP	27292025
MIRT452359	hsa-miR-6127	PAR-CLIP	27292025
MIRT452359	hsa-miR-6127	PAR-CLIP	27292025
MIRT452358	hsa-miR-6129	PAR-CLIP	27292025
MIRT452358	hsa-miR-6129	PAR-CLIP	27292025
MIRT452358	hsa-miR-6129	PAR-CLIP	27292025
MIRT452358	hsa-miR-6129	PAR-CLIP	27292025
MIRT452358	hsa-miR-6129	PAR-CLIP	27292025
MIRT452357	hsa-miR-6130	PAR-CLIP	27292025
MIRT452357	hsa-miR-6130	PAR-CLIP	27292025
MIRT452357	hsa-miR-6130	PAR-CLIP	27292025
MIRT452357	hsa-miR-6130	PAR-CLIP	27292025
MIRT452357	hsa-miR-6130	PAR-CLIP	27292025
MIRT452356	hsa-miR-6133	PAR-CLIP	27292025
MIRT452356	hsa-miR-6133	PAR-CLIP	27292025
MIRT452356	hsa-miR-6133	PAR-CLIP	27292025
MIRT452356	hsa-miR-6133	PAR-CLIP	27292025
MIRT452356	hsa-miR-6133	PAR-CLIP	27292025
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	27292025
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	27292025
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	27292025
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	27292025
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	27292025
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	27292025
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	27292025
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	27292025
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	27292025
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	27292025
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	27292025
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	27292025
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	27292025
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	27292025
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	27292025
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	27292025
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	27292025
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	27292025
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	27292025
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	27292025
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	27292025
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	27292025
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	27292025
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	27292025
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	27292025
MIRT452350	hsa-miR-8085	PAR-CLIP	27292025
MIRT452350	hsa-miR-8085	PAR-CLIP	27292025
MIRT452350	hsa-miR-8085	PAR-CLIP	27292025
MIRT452350	hsa-miR-8085	PAR-CLIP	27292025
MIRT452350	hsa-miR-8085	PAR-CLIP	27292025
MIRT452367	hsa-miR-4428	PAR-CLIP	20371350
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	20371350
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	20371350
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	20371350
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	20371350
MIRT452361	hsa-miR-4419a	PAR-CLIP	20371350
MIRT452360	hsa-miR-4510	PAR-CLIP	20371350
MIRT452359	hsa-miR-6127	PAR-CLIP	20371350
MIRT452358	hsa-miR-6129	PAR-CLIP	20371350
MIRT452357	hsa-miR-6130	PAR-CLIP	20371350
MIRT452356	hsa-miR-6133	PAR-CLIP	20371350
MIRT452355	hsa-miR-185-5p	PAR-CLIP	20371350
MIRT452354	hsa-miR-4306	PAR-CLIP	20371350
MIRT452353	hsa-miR-4644	PAR-CLIP	20371350
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT452350	hsa-miR-8085	PAR-CLIP	20371350
MIRT452367	hsa-miR-4428	PAR-CLIP	22012620
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	22012620
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	22012620
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	22012620
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	22012620
MIRT452361	hsa-miR-4419a	PAR-CLIP	22012620
MIRT452360	hsa-miR-4510	PAR-CLIP	22012620
MIRT452359	hsa-miR-6127	PAR-CLIP	22012620
MIRT452358	hsa-miR-6129	PAR-CLIP	22012620
MIRT452357	hsa-miR-6130	PAR-CLIP	22012620
MIRT452356	hsa-miR-6133	PAR-CLIP	22012620
MIRT452355	hsa-miR-185-5p	PAR-CLIP	22012620
MIRT452354	hsa-miR-4306	PAR-CLIP	22012620
MIRT452353	hsa-miR-4644	PAR-CLIP	22012620
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	22012620
MIRT452350	hsa-miR-8085	PAR-CLIP	22012620
MIRT452351	hsa-miR-5739	PAR-CLIP	22012620
MIRT452367	hsa-miR-4428	PAR-CLIP	24398324
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	24398324
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	24398324
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	24398324
MIRT452361	hsa-miR-4419a	PAR-CLIP	24398324
MIRT452360	hsa-miR-4510	PAR-CLIP	24398324
MIRT452359	hsa-miR-6127	PAR-CLIP	24398324
MIRT452358	hsa-miR-6129	PAR-CLIP	24398324
MIRT452357	hsa-miR-6130	PAR-CLIP	24398324
MIRT452356	hsa-miR-6133	PAR-CLIP	24398324
MIRT452355	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT452354	hsa-miR-4306	PAR-CLIP	24398324
MIRT452353	hsa-miR-4644	PAR-CLIP	24398324
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT452350	hsa-miR-8085	PAR-CLIP	24398324
MIRT452351	hsa-miR-5739	PAR-CLIP	24398324
MIRT452367	hsa-miR-4428	PAR-CLIP	23592263
MIRT494114	hsa-miR-3123	PAR-CLIP	23592263
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452361	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452360	hsa-miR-4510	PAR-CLIP	23592263
MIRT452359	hsa-miR-6127	PAR-CLIP	23592263
MIRT452358	hsa-miR-6129	PAR-CLIP	23592263
MIRT452357	hsa-miR-6130	PAR-CLIP	23592263
MIRT452356	hsa-miR-6133	PAR-CLIP	23592263
MIRT452355	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT452354	hsa-miR-4306	PAR-CLIP	23592263
MIRT452353	hsa-miR-4644	PAR-CLIP	23592263
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT452350	hsa-miR-8085	PAR-CLIP	23592263
MIRT452351	hsa-miR-5739	PAR-CLIP	23592263
MIRT452367	hsa-miR-4428	PAR-CLIP	23592263
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452361	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452360	hsa-miR-4510	PAR-CLIP	23592263
MIRT452359	hsa-miR-6127	PAR-CLIP	23592263
MIRT452358	hsa-miR-6129	PAR-CLIP	23592263
MIRT452357	hsa-miR-6130	PAR-CLIP	23592263
MIRT452356	hsa-miR-6133	PAR-CLIP	23592263
MIRT452355	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT452354	hsa-miR-4306	PAR-CLIP	23592263
MIRT452353	hsa-miR-4644	PAR-CLIP	23592263
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT452350	hsa-miR-8085	PAR-CLIP	23592263
MIRT452351	hsa-miR-5739	PAR-CLIP	23592263
MIRT452367	hsa-miR-4428	PAR-CLIP	23592263
MIRT452365	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452364	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452363	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT452362	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452361	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452360	hsa-miR-4510	PAR-CLIP	23592263
MIRT452359	hsa-miR-6127	PAR-CLIP	23592263
MIRT452358	hsa-miR-6129	PAR-CLIP	23592263
MIRT452357	hsa-miR-6130	PAR-CLIP	23592263
MIRT452356	hsa-miR-6133	PAR-CLIP	23592263
MIRT452355	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT452354	hsa-miR-4306	PAR-CLIP	23592263
MIRT452353	hsa-miR-4644	PAR-CLIP	23592263
MIRT452352	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT452350	hsa-miR-8085	PAR-CLIP	23592263
MIRT452351	hsa-miR-5739	PAR-CLIP	23592263
MIRT939023	hsa-miR-1252	CLIP-seq
MIRT939024	hsa-miR-1253	CLIP-seq
MIRT939025	hsa-miR-150	CLIP-seq
MIRT939026	hsa-miR-185	CLIP-seq
MIRT939027	hsa-miR-2113	CLIP-seq
MIRT939028	hsa-miR-3064-3p	CLIP-seq
MIRT939029	hsa-miR-3119	CLIP-seq
MIRT939030	hsa-miR-3145-5p	CLIP-seq
MIRT939031	hsa-miR-3670	CLIP-seq
MIRT939032	hsa-miR-4311	CLIP-seq
MIRT939033	hsa-miR-4474-3p	CLIP-seq
MIRT939034	hsa-miR-4715-3p	CLIP-seq
MIRT939035	hsa-miR-4802-5p	CLIP-seq
MIRT939036	hsa-miR-508-5p	CLIP-seq
MIRT939037	hsa-miR-556-5p	CLIP-seq
MIRT939038	hsa-miR-765	CLIP-seq
MIRT939026	hsa-miR-185	CLIP-seq
MIRT1556228	hsa-miR-4651	CLIP-seq
MIRT1556229	hsa-miR-608	CLIP-seq
MIRT2213141	hsa-miR-103a	CLIP-seq
MIRT2213142	hsa-miR-107	CLIP-seq
MIRT2213143	hsa-miR-1179	CLIP-seq
MIRT2213144	hsa-miR-204	CLIP-seq
MIRT2213145	hsa-miR-211	CLIP-seq
MIRT2213146	hsa-miR-3674	CLIP-seq
MIRT2213147	hsa-miR-3938	CLIP-seq
MIRT2213148	hsa-miR-4310	CLIP-seq
MIRT1556228	hsa-miR-4651	CLIP-seq
MIRT2213149	hsa-miR-4755-5p	CLIP-seq
MIRT1556229	hsa-miR-608	CLIP-seq
MIRT2213150	hsa-miR-623	CLIP-seq
MIRT939026	hsa-miR-185	CLIP-seq
MIRT2448337	hsa-miR-1178	CLIP-seq
MIRT2448338	hsa-miR-1200	CLIP-seq
MIRT2448339	hsa-miR-1238	CLIP-seq
MIRT2448340	hsa-miR-1273f	CLIP-seq
MIRT2448341	hsa-miR-143	CLIP-seq
MIRT2448342	hsa-miR-219-5p	CLIP-seq
MIRT2448343	hsa-miR-3074-5p	CLIP-seq
MIRT2448344	hsa-miR-3124-3p	CLIP-seq
MIRT2448345	hsa-miR-330-3p	CLIP-seq
MIRT2448346	hsa-miR-335	CLIP-seq
MIRT2448347	hsa-miR-3646	CLIP-seq
MIRT2448348	hsa-miR-377	CLIP-seq
MIRT2448349	hsa-miR-3921	CLIP-seq
MIRT2448350	hsa-miR-3927	CLIP-seq
MIRT2448351	hsa-miR-3942-5p	CLIP-seq
MIRT2448352	hsa-miR-4251	CLIP-seq
MIRT2448353	hsa-miR-4275	CLIP-seq
MIRT2448354	hsa-miR-4329	CLIP-seq
MIRT2448355	hsa-miR-4445	CLIP-seq
MIRT2448356	hsa-miR-4643	CLIP-seq
MIRT2448357	hsa-miR-4650-3p	CLIP-seq
MIRT2448358	hsa-miR-4653-5p	CLIP-seq
MIRT2448359	hsa-miR-4691-5p	CLIP-seq
MIRT2448360	hsa-miR-4696	CLIP-seq
MIRT2448361	hsa-miR-4703-5p	CLIP-seq
MIRT2448362	hsa-miR-4708-5p	CLIP-seq
MIRT939034	hsa-miR-4715-3p	CLIP-seq
MIRT2448363	hsa-miR-4768-5p	CLIP-seq
MIRT2448364	hsa-miR-4770	CLIP-seq
MIRT2448365	hsa-miR-4782-3p	CLIP-seq
MIRT2448366	hsa-miR-4790-3p	CLIP-seq
MIRT2448367	hsa-miR-488	CLIP-seq
MIRT2448368	hsa-miR-508-3p	CLIP-seq
MIRT2448369	hsa-miR-539	CLIP-seq
MIRT2448370	hsa-miR-548ag	CLIP-seq
MIRT2448371	hsa-miR-548ai	CLIP-seq
MIRT2448372	hsa-miR-548an	CLIP-seq
MIRT2448373	hsa-miR-548m	CLIP-seq
MIRT2448374	hsa-miR-628-3p	CLIP-seq

Show/Hide all (23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001501	Process	Skeletal system development	TAS	7907794
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	TAS	7907794
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007399	Process	Nervous system development	TAS	7907794
GO:0030154	Process	Cell differentiation	IBA
GO:0030326	Process	Embryonic limb morphogenesis	IEA
GO:0030855	Process	Epithelial cell differentiation	IEA
GO:0042472	Process	Inner ear morphogenesis	IEA
GO:0048646	Process	Anatomical structure formation involved in morphogenesis	IEA
GO:0048706	Process	Embryonic skeletal system development	IBA
GO:0050679	Process	Positive regulation of epithelial cell proliferation	IEA
GO:0060021	Process	Roof of mouth development	IEA
GO:0060322	Process	Head development	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
600030	2919	ENSG00000006377

P56179

Protein name

Homeobox protein DLX-6

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	50 → 106	Homeodomain	Domain

Sequence

MSHSQHSPYLQSYHNSSAAAQTRGDDTDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQ
LQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPL
QGSAALSPRSPALPPVWDVSASAKGVSMPPNSYMPGYSHWYSSPHQDTMQRPQMM

Sequence length

175

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (9)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	GenCC	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CRANIOFACIAL ABNORMALITIES	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DESBUQUOIS SYNDROME	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DLX6-related disorder	Uncertain significance; Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ECTRODACTYLY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPLIT HAND-FOOT MALFORMATION	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (50)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Aniridia	Aniridia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	Pubtator	32108034	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	28321286	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorders	Autism Spectrum Disorder	BEFREE	19195802		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic Disorder	Autism	BEFREE	12707945, 19195802		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	35668376	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	28881158	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Adenoid Cystic	Adenoid cystic carcinoma	Pubtator	26953815	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	30805988, 36204642	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	31081076	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	28881158	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	31885738, 34697393	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Foot Deformity	Congenital deformity of foot	BEFREE	17230488, 23169702, 8733122		★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	27622494	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic retinopathy	Pubtator	36187126	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ectrodactyly	Ectrodactyly	BEFREE	12112878, 22342398		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectrodactyly	Ectrodactyly	Pubtator	25231166, 27291887	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectrodactyly	Ectrodactyly	ORPHANET_DG	28611547		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	35578166	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	32513296	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Isolated split hand-split foot malformation	Isolated Split Hand-Split Foot Malformation	Orphanet			★★★★★ ★☆☆☆☆ Found in Text Mining only
Limb Deformities, Congenital	Congenital anomaly of limb	BEFREE	11719259		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	31081076	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	33550924	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	31782911	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	18316591, 31190891		★★★★★ ★☆☆☆☆ Found in Text Mining only
nervous system disorder	Nervous System Disorder	BEFREE	29618965		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	26786290	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	31190891		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oligodactyly	Oligodactyly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Failure, Premature	Ovarian Failure	BEFREE	21505076		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pierre Robin Syndrome	Pierre-Robin Syndrome	BEFREE	24699068		★★★★★ ★☆☆☆☆ Found in Text Mining only
Premature Menopause	Premature Menopause	BEFREE	21505076		★★★★★ ★☆☆☆☆ Found in Text Mining only
RAPP-HODGKIN SYNDROME	RAPP-HODGKIN SYNDROME	BEFREE	22342398		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rett Syndrome	Rett Syndrome	BEFREE	17701895		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	28321286	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Sensorineural Hearing Loss (disorder)	Hearing Loss	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Split foot	Split Hand Foot Deformity	BEFREE	17230488, 23169702		★★★★★ ★☆☆☆☆ Found in Text Mining only
Split hand foot deformity 1	Split hand foot deformity	BEFREE	12112878, 17230488, 22342398, 23169702, 26839112		★★★★★ ★☆☆☆☆ Found in Text Mining only
Split hand foot deformity 1	Split hand foot deformity	GENOMICS_ENGLAND_DG	28611547		★★★★★ ★☆☆☆☆ Found in Text Mining only
Split-Hand-Foot Malformation With Sensorineural Hearing Loss	Split-Hand-Foot Malformation With Sensorineural Hearing Loss	GENOMICS_ENGLAND_DG	28611547		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	30592268		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	31591939	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Syndactyly of fingers	Syndactyly of fingers	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
T-Cell Lymphoma	T-Cell Lymphoma	BEFREE	18316591		★★★★★ ★☆☆☆☆ Found in Text Mining only
Tetralogy of Fallot	Tetralogy of fallot	Pubtator	30582441	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	31858555	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Trichohepatoenteric Syndrome	Trichohepatoenteric Syndrome	BEFREE	19707792		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uranostaphyloschisis	Uranostaphyloschisis	BEFREE	24699068		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	33550924	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only

DLX6 (distal-less homeobox 6)