DIO2 (iodothyronine deiodinase 2)

Gene

• Entrez ID: 1734
• Gene name: Iodothyronine deiodinase 2
• Gene symbol: DIO2
• Synonyms (NCBI Gene): 5DII, D2, DIOII, SELENOY, SelY, TXDI2
• Chromosome: 14
• Chromosome location: 14q31.1
• Summary: The protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3`,5`-tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3`-triiodothyronine, T3) by outer ring 5`-deiodin

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT668748	hsa-miR-4453	HITS-CLIP	23824327
MIRT668747	hsa-miR-4538	HITS-CLIP	23824327
MIRT668746	hsa-miR-5193	HITS-CLIP	23824327
MIRT668745	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT668744	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT668743	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT668742	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT668741	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT668740	hsa-miR-1257	HITS-CLIP	23824327
MIRT668739	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT668738	hsa-miR-7975	HITS-CLIP	23824327
MIRT668737	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT668736	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT668735	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT668734	hsa-miR-3685	HITS-CLIP	23824327
MIRT668733	hsa-miR-384	HITS-CLIP	23824327
MIRT668732	hsa-miR-544a	HITS-CLIP	23824327
MIRT668731	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT628266	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT628265	hsa-miR-4282	HITS-CLIP	23824327
MIRT628264	hsa-miR-5009-3p	HITS-CLIP	23824327
MIRT668748	hsa-miR-4453	HITS-CLIP	23824327
MIRT668747	hsa-miR-4538	HITS-CLIP	23824327
MIRT668746	hsa-miR-5193	HITS-CLIP	23824327
MIRT668745	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT668744	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT668743	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT668742	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT668741	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT668740	hsa-miR-1257	HITS-CLIP	23824327
MIRT668739	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT668738	hsa-miR-7975	HITS-CLIP	23824327
MIRT668737	hsa-miR-4727-5p	HITS-CLIP	23824327
MIRT668736	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT668735	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT668734	hsa-miR-3685	HITS-CLIP	23824327
MIRT668733	hsa-miR-384	HITS-CLIP	23824327
MIRT668732	hsa-miR-544a	HITS-CLIP	23824327
MIRT668731	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT628266	hsa-miR-548e-5p	HITS-CLIP	23824327
MIRT628265	hsa-miR-4282	HITS-CLIP	23824327
MIRT628264	hsa-miR-5009-3p	HITS-CLIP	23824327
MIRT936584	hsa-miR-297	CLIP-seq
MIRT936585	hsa-miR-3176	CLIP-seq
MIRT936586	hsa-miR-3922-3p	CLIP-seq
MIRT936587	hsa-miR-4307	CLIP-seq
MIRT936588	hsa-miR-4312	CLIP-seq
MIRT936589	hsa-miR-567	CLIP-seq
MIRT936590	hsa-miR-581	CLIP-seq
MIRT936591	hsa-miR-4269	CLIP-seq
MIRT936592	hsa-miR-450b-5p	CLIP-seq
MIRT936593	hsa-miR-4514	CLIP-seq
MIRT936594	hsa-miR-4641	CLIP-seq
MIRT936595	hsa-miR-4692	CLIP-seq
MIRT936596	hsa-miR-4698	CLIP-seq
MIRT936597	hsa-miR-4742-5p	CLIP-seq
MIRT936598	hsa-miR-507	CLIP-seq
MIRT936599	hsa-miR-510	CLIP-seq
MIRT936600	hsa-miR-557	CLIP-seq
MIRT936601	hsa-miR-1179	CLIP-seq
MIRT936602	hsa-miR-125a-5p	CLIP-seq
MIRT936603	hsa-miR-125b	CLIP-seq
MIRT936604	hsa-miR-3150a-3p	CLIP-seq
MIRT936605	hsa-miR-3175	CLIP-seq
MIRT936606	hsa-miR-3618	CLIP-seq
MIRT936607	hsa-miR-3651	CLIP-seq
MIRT936608	hsa-miR-374a	CLIP-seq
MIRT936609	hsa-miR-374b	CLIP-seq
MIRT936610	hsa-miR-4319	CLIP-seq
MIRT936611	hsa-miR-4426	CLIP-seq
MIRT936612	hsa-miR-4470	CLIP-seq
MIRT936613	hsa-miR-4528	CLIP-seq
MIRT936594	hsa-miR-4641	CLIP-seq
MIRT936614	hsa-miR-4647	CLIP-seq
MIRT936615	hsa-miR-4662b	CLIP-seq
MIRT936616	hsa-miR-4691-5p	CLIP-seq
MIRT936617	hsa-miR-4732-3p	CLIP-seq
MIRT936618	hsa-miR-670	CLIP-seq
MIRT936619	hsa-miR-759	CLIP-seq
MIRT936620	hsa-miR-939	CLIP-seq
MIRT1556223	hsa-miR-134	CLIP-seq
MIRT1556224	hsa-miR-3118	CLIP-seq
MIRT1556225	hsa-miR-668	CLIP-seq
MIRT1556226	hsa-miR-943	CLIP-seq
MIRT936602	hsa-miR-125a-5p	CLIP-seq
MIRT936603	hsa-miR-125b	CLIP-seq
MIRT936607	hsa-miR-3651	CLIP-seq
MIRT936610	hsa-miR-4319	CLIP-seq
MIRT936616	hsa-miR-4691-5p	CLIP-seq
MIRT936617	hsa-miR-4732-3p	CLIP-seq
MIRT936618	hsa-miR-670	CLIP-seq
MIRT936602	hsa-miR-125a-5p	CLIP-seq
MIRT936603	hsa-miR-125b	CLIP-seq
MIRT936607	hsa-miR-3651	CLIP-seq
MIRT936610	hsa-miR-4319	CLIP-seq
MIRT936616	hsa-miR-4691-5p	CLIP-seq
MIRT936617	hsa-miR-4732-3p	CLIP-seq
MIRT936618	hsa-miR-670	CLIP-seq
MIRT936602	hsa-miR-125a-5p	CLIP-seq
MIRT936603	hsa-miR-125b	CLIP-seq
MIRT936607	hsa-miR-3651	CLIP-seq
MIRT936610	hsa-miR-4319	CLIP-seq
MIRT936616	hsa-miR-4691-5p	CLIP-seq
MIRT936617	hsa-miR-4732-3p	CLIP-seq
MIRT936618	hsa-miR-670	CLIP-seq
MIRT1977136	hsa-miR-4802-3p	CLIP-seq
MIRT1977137	hsa-miR-548a-5p	CLIP-seq
MIRT1977138	hsa-miR-548ab	CLIP-seq
MIRT1977139	hsa-miR-548ak	CLIP-seq
MIRT1977140	hsa-miR-548b-5p	CLIP-seq
MIRT1977141	hsa-miR-548c-5p	CLIP-seq
MIRT1977142	hsa-miR-548d-5p	CLIP-seq
MIRT1977143	hsa-miR-548h	CLIP-seq
MIRT1977144	hsa-miR-548i	CLIP-seq
MIRT1977145	hsa-miR-548j	CLIP-seq
MIRT1977146	hsa-miR-548n	CLIP-seq
MIRT1977147	hsa-miR-548w	CLIP-seq
MIRT1977148	hsa-miR-548y	CLIP-seq
MIRT1977149	hsa-miR-559	CLIP-seq
MIRT1977150	hsa-miR-944	CLIP-seq
MIRT2212514	hsa-miR-4666-3p	CLIP-seq
MIRT2212515	hsa-miR-3123	CLIP-seq
MIRT2212516	hsa-miR-3973	CLIP-seq
MIRT2212517	hsa-miR-4477a	CLIP-seq
MIRT2212518	hsa-miR-4729	CLIP-seq
MIRT2212519	hsa-miR-579	CLIP-seq
MIRT2212520	hsa-miR-629	CLIP-seq
MIRT2212521	hsa-miR-935	CLIP-seq
MIRT2516249	hsa-miR-1323	CLIP-seq
MIRT2516250	hsa-miR-216a	CLIP-seq
MIRT2516251	hsa-miR-3164	CLIP-seq
MIRT2516252	hsa-miR-4434	CLIP-seq
MIRT2516253	hsa-miR-4516	CLIP-seq
MIRT2516254	hsa-miR-4677-5p	CLIP-seq
MIRT2212518	hsa-miR-4729	CLIP-seq
MIRT2516255	hsa-miR-502-5p	CLIP-seq
MIRT2516256	hsa-miR-544	CLIP-seq
MIRT2516257	hsa-miR-548o	CLIP-seq
MIRT2516258	hsa-miR-659	CLIP-seq
MIRT2212521	hsa-miR-935	CLIP-seq
MIRT2516259	hsa-miR-103a	CLIP-seq
MIRT2516260	hsa-miR-107	CLIP-seq
MIRT2516261	hsa-miR-1178	CLIP-seq
MIRT2516262	hsa-miR-1202	CLIP-seq
MIRT2516263	hsa-miR-1229	CLIP-seq
MIRT2516264	hsa-miR-1237	CLIP-seq
MIRT2516265	hsa-miR-1243	CLIP-seq
MIRT2516266	hsa-miR-1244	CLIP-seq
MIRT2516267	hsa-miR-1245b-3p	CLIP-seq
MIRT2516268	hsa-miR-1253	CLIP-seq
MIRT2516269	hsa-miR-1254	CLIP-seq
MIRT2516270	hsa-miR-1261	CLIP-seq
MIRT2516271	hsa-miR-1264	CLIP-seq
MIRT2516272	hsa-miR-1266	CLIP-seq
MIRT2516273	hsa-miR-1278	CLIP-seq
MIRT2516274	hsa-miR-1280	CLIP-seq
MIRT2516275	hsa-miR-1284	CLIP-seq
MIRT2516276	hsa-miR-1301	CLIP-seq
MIRT2516277	hsa-miR-1304	CLIP-seq
MIRT2516278	hsa-miR-1305	CLIP-seq
MIRT2516249	hsa-miR-1323	CLIP-seq
MIRT1556223	hsa-miR-134	CLIP-seq
MIRT2516279	hsa-miR-142-5p	CLIP-seq
MIRT2516280	hsa-miR-147b	CLIP-seq
MIRT2516281	hsa-miR-150	CLIP-seq
MIRT2516282	hsa-miR-1587	CLIP-seq
MIRT2516283	hsa-miR-190	CLIP-seq
MIRT2516284	hsa-miR-190b	CLIP-seq
MIRT2516285	hsa-miR-1912	CLIP-seq
MIRT2516286	hsa-miR-193a-3p	CLIP-seq
MIRT2516287	hsa-miR-193a-5p	CLIP-seq
MIRT2516288	hsa-miR-193b	CLIP-seq
MIRT2516289	hsa-miR-197	CLIP-seq
MIRT2516290	hsa-miR-199a-3p	CLIP-seq
MIRT2516291	hsa-miR-199b-3p	CLIP-seq
MIRT2516292	hsa-miR-205	CLIP-seq
MIRT2516293	hsa-miR-2052	CLIP-seq
MIRT2516294	hsa-miR-208a	CLIP-seq
MIRT2516295	hsa-miR-208b	CLIP-seq
MIRT2516296	hsa-miR-2116	CLIP-seq
MIRT2516250	hsa-miR-216a	CLIP-seq
MIRT2516297	hsa-miR-216b	CLIP-seq
MIRT2516298	hsa-miR-223	CLIP-seq
MIRT2516299	hsa-miR-224	CLIP-seq
MIRT2516300	hsa-miR-2276	CLIP-seq
MIRT2516301	hsa-miR-23a	CLIP-seq
MIRT2516302	hsa-miR-23b	CLIP-seq
MIRT2516303	hsa-miR-23c	CLIP-seq
MIRT2516304	hsa-miR-2861	CLIP-seq
MIRT2516305	hsa-miR-300	CLIP-seq
MIRT2516306	hsa-miR-302f	CLIP-seq
MIRT2516307	hsa-miR-3116	CLIP-seq
MIRT1556224	hsa-miR-3118	CLIP-seq
MIRT2516308	hsa-miR-3119	CLIP-seq
MIRT2516309	hsa-miR-3120-5p	CLIP-seq
MIRT2516310	hsa-miR-3122	CLIP-seq
MIRT2212515	hsa-miR-3123	CLIP-seq
MIRT2516311	hsa-miR-3127-3p	CLIP-seq
MIRT2516312	hsa-miR-3127-5p	CLIP-seq
MIRT2516313	hsa-miR-3129-3p	CLIP-seq
MIRT2516314	hsa-miR-3129-5p	CLIP-seq
MIRT2516315	hsa-miR-3130-3p	CLIP-seq
MIRT2516316	hsa-miR-3130-5p	CLIP-seq
MIRT2516317	hsa-miR-3135	CLIP-seq
MIRT2516318	hsa-miR-3136-3p	CLIP-seq
MIRT936604	hsa-miR-3150a-3p	CLIP-seq
MIRT2516319	hsa-miR-3150a-5p	CLIP-seq
MIRT2516320	hsa-miR-3150b-5p	CLIP-seq
MIRT2516321	hsa-miR-3157-5p	CLIP-seq
MIRT2516322	hsa-miR-3160-5p	CLIP-seq
MIRT2516323	hsa-miR-3162-3p	CLIP-seq
MIRT2516251	hsa-miR-3164	CLIP-seq
MIRT2516324	hsa-miR-3173-3p	CLIP-seq
MIRT2516325	hsa-miR-3174	CLIP-seq
MIRT936605	hsa-miR-3175	CLIP-seq
MIRT2516326	hsa-miR-3181	CLIP-seq
MIRT2516327	hsa-miR-3182	CLIP-seq
MIRT2516328	hsa-miR-3184	CLIP-seq
MIRT2516329	hsa-miR-3194-3p	CLIP-seq
MIRT2516330	hsa-miR-3194-5p	CLIP-seq
MIRT2516331	hsa-miR-3200-3p	CLIP-seq
MIRT2516332	hsa-miR-3200-5p	CLIP-seq
MIRT2516333	hsa-miR-3201	CLIP-seq
MIRT2516334	hsa-miR-320e	CLIP-seq
MIRT2516335	hsa-miR-323-3p	CLIP-seq
MIRT2516336	hsa-miR-330-3p	CLIP-seq
MIRT2516337	hsa-miR-340	CLIP-seq
MIRT2516338	hsa-miR-3529	CLIP-seq
MIRT2516339	hsa-miR-361-3p	CLIP-seq
MIRT2516340	hsa-miR-3614-3p	CLIP-seq
MIRT2516341	hsa-miR-3654	CLIP-seq
MIRT2516342	hsa-miR-3660	CLIP-seq
MIRT2516343	hsa-miR-3664-5p	CLIP-seq
MIRT2516344	hsa-miR-3667-3p	CLIP-seq
MIRT2516345	hsa-miR-3671	CLIP-seq
MIRT2516346	hsa-miR-3677-5p	CLIP-seq
MIRT2516347	hsa-miR-374c	CLIP-seq
MIRT2516348	hsa-miR-376c	CLIP-seq
MIRT2516349	hsa-miR-379	CLIP-seq
MIRT2516350	hsa-miR-381	CLIP-seq
MIRT2516351	hsa-miR-3913-5p	CLIP-seq
MIRT2516352	hsa-miR-3914	CLIP-seq
MIRT2516353	hsa-miR-3918	CLIP-seq
MIRT2516354	hsa-miR-3925-5p	CLIP-seq
MIRT2516355	hsa-miR-3926	CLIP-seq
MIRT2516356	hsa-miR-3938	CLIP-seq
MIRT2516357	hsa-miR-3944-3p	CLIP-seq
MIRT2516358	hsa-miR-3972	CLIP-seq
MIRT2212516	hsa-miR-3973	CLIP-seq
MIRT2516359	hsa-miR-3976	CLIP-seq
MIRT2516360	hsa-miR-3977	CLIP-seq
MIRT2516361	hsa-miR-412	CLIP-seq
MIRT2516362	hsa-miR-423-5p	CLIP-seq
MIRT2516363	hsa-miR-4251	CLIP-seq
MIRT2516364	hsa-miR-4254	CLIP-seq
MIRT2516365	hsa-miR-4270	CLIP-seq
MIRT2516366	hsa-miR-4273	CLIP-seq
MIRT2516367	hsa-miR-4274	CLIP-seq
MIRT2516368	hsa-miR-4279	CLIP-seq
MIRT2516369	hsa-miR-4287	CLIP-seq
MIRT2516370	hsa-miR-4292	CLIP-seq
MIRT2516371	hsa-miR-4297	CLIP-seq
MIRT2516372	hsa-miR-4299	CLIP-seq
MIRT2516373	hsa-miR-4302	CLIP-seq
MIRT936587	hsa-miR-4307	CLIP-seq
MIRT2516374	hsa-miR-4308	CLIP-seq
MIRT936588	hsa-miR-4312	CLIP-seq
MIRT2516375	hsa-miR-4318	CLIP-seq
MIRT2516376	hsa-miR-4329	CLIP-seq
MIRT2516377	hsa-miR-4330	CLIP-seq
MIRT936611	hsa-miR-4426	CLIP-seq
MIRT2516378	hsa-miR-4428	CLIP-seq
MIRT2516252	hsa-miR-4434	CLIP-seq
MIRT2516379	hsa-miR-4436b-3p	CLIP-seq
MIRT2516380	hsa-miR-4441	CLIP-seq
MIRT2516381	hsa-miR-4449	CLIP-seq
MIRT2516382	hsa-miR-4451	CLIP-seq
MIRT2516383	hsa-miR-4456	CLIP-seq
MIRT2516384	hsa-miR-4462	CLIP-seq
MIRT2516385	hsa-miR-4468	CLIP-seq
MIRT2516386	hsa-miR-4469	CLIP-seq
MIRT936612	hsa-miR-4470	CLIP-seq
MIRT2516387	hsa-miR-4476	CLIP-seq
MIRT2516388	hsa-miR-4477b	CLIP-seq
MIRT2516389	hsa-miR-4482	CLIP-seq
MIRT2516390	hsa-miR-4487	CLIP-seq
MIRT2516391	hsa-miR-4490	CLIP-seq
MIRT2516392	hsa-miR-4494	CLIP-seq
MIRT2516393	hsa-miR-4499	CLIP-seq
MIRT2516394	hsa-miR-4501	CLIP-seq
MIRT2516395	hsa-miR-4504	CLIP-seq
MIRT2516396	hsa-miR-4512	CLIP-seq
MIRT2516253	hsa-miR-4516	CLIP-seq
MIRT2516397	hsa-miR-4518	CLIP-seq
MIRT2516398	hsa-miR-452	CLIP-seq
MIRT2516399	hsa-miR-4521	CLIP-seq
MIRT2516400	hsa-miR-4522	CLIP-seq
MIRT2516401	hsa-miR-4526	CLIP-seq
MIRT2516402	hsa-miR-4531	CLIP-seq
MIRT2516403	hsa-miR-4633-3p	CLIP-seq
MIRT2516404	hsa-miR-4637	CLIP-seq
MIRT2516405	hsa-miR-4639-3p	CLIP-seq
MIRT2516406	hsa-miR-4643	CLIP-seq
MIRT936614	hsa-miR-4647	CLIP-seq
MIRT2516407	hsa-miR-4650-3p	CLIP-seq
MIRT2516408	hsa-miR-4659a-3p	CLIP-seq
MIRT2516409	hsa-miR-4659b-3p	CLIP-seq
MIRT2516410	hsa-miR-466	CLIP-seq
MIRT936615	hsa-miR-4662b	CLIP-seq
MIRT2212514	hsa-miR-4666-3p	CLIP-seq
MIRT2516411	hsa-miR-4674	CLIP-seq
MIRT2516412	hsa-miR-4676-3p	CLIP-seq
MIRT2516413	hsa-miR-4676-5p	CLIP-seq
MIRT2516414	hsa-miR-4677-3p	CLIP-seq
MIRT2516254	hsa-miR-4677-5p	CLIP-seq
MIRT2516415	hsa-miR-4679	CLIP-seq
MIRT2516416	hsa-miR-4685-3p	CLIP-seq
MIRT2516417	hsa-miR-4686	CLIP-seq
MIRT2516418	hsa-miR-4687-5p	CLIP-seq
MIRT2516419	hsa-miR-4693-5p	CLIP-seq
MIRT2516420	hsa-miR-4709-5p	CLIP-seq
MIRT2516421	hsa-miR-4713-5p	CLIP-seq
MIRT2516422	hsa-miR-4716-3p	CLIP-seq
MIRT2516423	hsa-miR-4723-5p	CLIP-seq
MIRT2516424	hsa-miR-4728-5p	CLIP-seq
MIRT2212518	hsa-miR-4729	CLIP-seq
MIRT2516425	hsa-miR-4737	CLIP-seq
MIRT2516426	hsa-miR-4738-3p	CLIP-seq
MIRT2516427	hsa-miR-4750	CLIP-seq
MIRT2516428	hsa-miR-4755-3p	CLIP-seq
MIRT2516429	hsa-miR-4761-3p	CLIP-seq
MIRT2516430	hsa-miR-4762-5p	CLIP-seq
MIRT2516431	hsa-miR-4767	CLIP-seq
MIRT2516432	hsa-miR-4772-3p	CLIP-seq
MIRT2516433	hsa-miR-4774-5p	CLIP-seq
MIRT2516434	hsa-miR-4781-3p	CLIP-seq
MIRT2516435	hsa-miR-4785	CLIP-seq
MIRT2516436	hsa-miR-4786-5p	CLIP-seq
MIRT2516437	hsa-miR-4789-3p	CLIP-seq
MIRT2516438	hsa-miR-4789-5p	CLIP-seq
MIRT2516439	hsa-miR-4791	CLIP-seq
MIRT2516440	hsa-miR-4793-3p	CLIP-seq
MIRT2516441	hsa-miR-4793-5p	CLIP-seq
MIRT2516442	hsa-miR-4795-5p	CLIP-seq
MIRT1977136	hsa-miR-4802-3p	CLIP-seq
MIRT2516443	hsa-miR-483-5p	CLIP-seq
MIRT2516444	hsa-miR-487b	CLIP-seq
MIRT2516445	hsa-miR-494	CLIP-seq
MIRT2516446	hsa-miR-499a-5p	CLIP-seq
MIRT2516447	hsa-miR-501-3p	CLIP-seq
MIRT2516448	hsa-miR-502-3p	CLIP-seq
MIRT2516255	hsa-miR-502-5p	CLIP-seq
MIRT2516449	hsa-miR-5047	CLIP-seq
MIRT2516450	hsa-miR-509-3p	CLIP-seq
MIRT2516451	hsa-miR-517b	CLIP-seq
MIRT2516452	hsa-miR-520d-5p	CLIP-seq
MIRT2516453	hsa-miR-524-5p	CLIP-seq
MIRT2516454	hsa-miR-526b	CLIP-seq
MIRT2516455	hsa-miR-532-3p	CLIP-seq
MIRT2516456	hsa-miR-543	CLIP-seq
MIRT2516256	hsa-miR-544	CLIP-seq
MIRT2516457	hsa-miR-548a-3p	CLIP-seq
MIRT1977137	hsa-miR-548a-5p	CLIP-seq
MIRT2516458	hsa-miR-548aa	CLIP-seq
MIRT1977138	hsa-miR-548ab	CLIP-seq
MIRT2516459	hsa-miR-548ac	CLIP-seq
MIRT2516460	hsa-miR-548ae	CLIP-seq
MIRT2516461	hsa-miR-548aj	CLIP-seq
MIRT1977139	hsa-miR-548ak	CLIP-seq
MIRT2516462	hsa-miR-548am	CLIP-seq
MIRT1977140	hsa-miR-548b-5p	CLIP-seq
MIRT1977141	hsa-miR-548c-5p	CLIP-seq
MIRT2516463	hsa-miR-548d-3p	CLIP-seq
MIRT1977142	hsa-miR-548d-5p	CLIP-seq
MIRT2516464	hsa-miR-548e	CLIP-seq
MIRT2516465	hsa-miR-548f	CLIP-seq
MIRT1977143	hsa-miR-548h	CLIP-seq
MIRT1977144	hsa-miR-548i	CLIP-seq
MIRT1977145	hsa-miR-548j	CLIP-seq
MIRT2516466	hsa-miR-548k	CLIP-seq
MIRT2516467	hsa-miR-548l	CLIP-seq
MIRT2516257	hsa-miR-548o	CLIP-seq
MIRT2516468	hsa-miR-548q	CLIP-seq
MIRT2516469	hsa-miR-548s	CLIP-seq
MIRT1977147	hsa-miR-548w	CLIP-seq
MIRT2516470	hsa-miR-548x	CLIP-seq
MIRT1977148	hsa-miR-548y	CLIP-seq
MIRT2516471	hsa-miR-548z	CLIP-seq
MIRT1977149	hsa-miR-559	CLIP-seq
MIRT2516472	hsa-miR-575	CLIP-seq
MIRT2212519	hsa-miR-579	CLIP-seq
MIRT2516473	hsa-miR-590-3p	CLIP-seq
MIRT2516474	hsa-miR-607	CLIP-seq
MIRT2516475	hsa-miR-617	CLIP-seq
MIRT2516476	hsa-miR-627	CLIP-seq
MIRT2212520	hsa-miR-629	CLIP-seq
MIRT2516477	hsa-miR-633	CLIP-seq
MIRT2516478	hsa-miR-635	CLIP-seq
MIRT2516479	hsa-miR-642a	CLIP-seq
MIRT2516480	hsa-miR-655	CLIP-seq
MIRT2516258	hsa-miR-659	CLIP-seq
MIRT2516481	hsa-miR-663b	CLIP-seq
MIRT1556225	hsa-miR-668	CLIP-seq
MIRT2516482	hsa-miR-769-5p	CLIP-seq
MIRT2516483	hsa-miR-890	CLIP-seq
MIRT2516484	hsa-miR-891b	CLIP-seq
MIRT2516485	hsa-miR-892a	CLIP-seq
MIRT2516486	hsa-miR-9	CLIP-seq
MIRT2516487	hsa-miR-921	CLIP-seq
MIRT2516488	hsa-miR-924	CLIP-seq
MIRT2212521	hsa-miR-935	CLIP-seq
MIRT2516489	hsa-miR-936	CLIP-seq
MIRT936620	hsa-miR-939	CLIP-seq
MIRT2516249	hsa-miR-1323	CLIP-seq
MIRT2516250	hsa-miR-216a	CLIP-seq
MIRT2516252	hsa-miR-4434	CLIP-seq
MIRT2516253	hsa-miR-4516	CLIP-seq
MIRT2212518	hsa-miR-4729	CLIP-seq
MIRT2516256	hsa-miR-544	CLIP-seq
MIRT2516257	hsa-miR-548o	CLIP-seq
MIRT2516259	hsa-miR-103a	CLIP-seq
MIRT2516260	hsa-miR-107	CLIP-seq
MIRT2516261	hsa-miR-1178	CLIP-seq
MIRT2516262	hsa-miR-1202	CLIP-seq
MIRT2516263	hsa-miR-1229	CLIP-seq
MIRT2516264	hsa-miR-1237	CLIP-seq
MIRT2516265	hsa-miR-1243	CLIP-seq
MIRT2516266	hsa-miR-1244	CLIP-seq
MIRT2516268	hsa-miR-1253	CLIP-seq
MIRT2516269	hsa-miR-1254	CLIP-seq
MIRT2516271	hsa-miR-1264	CLIP-seq
MIRT2516273	hsa-miR-1278	CLIP-seq
MIRT2516275	hsa-miR-1284	CLIP-seq
MIRT2516276	hsa-miR-1301	CLIP-seq
MIRT2516277	hsa-miR-1304	CLIP-seq
MIRT2516278	hsa-miR-1305	CLIP-seq
MIRT2516249	hsa-miR-1323	CLIP-seq
MIRT1556223	hsa-miR-134	CLIP-seq
MIRT2516279	hsa-miR-142-5p	CLIP-seq
MIRT2516282	hsa-miR-1587	CLIP-seq
MIRT2516285	hsa-miR-1912	CLIP-seq
MIRT2516286	hsa-miR-193a-3p	CLIP-seq
MIRT2516288	hsa-miR-193b	CLIP-seq
MIRT2516289	hsa-miR-197	CLIP-seq
MIRT2516290	hsa-miR-199a-3p	CLIP-seq
MIRT2516291	hsa-miR-199b-3p	CLIP-seq
MIRT2516292	hsa-miR-205	CLIP-seq
MIRT2516293	hsa-miR-2052	CLIP-seq
MIRT2516298	hsa-miR-223	CLIP-seq
MIRT2516299	hsa-miR-224	CLIP-seq
MIRT2516301	hsa-miR-23a	CLIP-seq
MIRT2516302	hsa-miR-23b	CLIP-seq
MIRT2516303	hsa-miR-23c	CLIP-seq
MIRT2516304	hsa-miR-2861	CLIP-seq
MIRT2516305	hsa-miR-300	CLIP-seq
MIRT2516306	hsa-miR-302f	CLIP-seq
MIRT2516307	hsa-miR-3116	CLIP-seq
MIRT1556224	hsa-miR-3118	CLIP-seq
MIRT2516308	hsa-miR-3119	CLIP-seq
MIRT2516309	hsa-miR-3120-5p	CLIP-seq
MIRT2212515	hsa-miR-3123	CLIP-seq
MIRT2516311	hsa-miR-3127-3p	CLIP-seq
MIRT2516313	hsa-miR-3129-3p	CLIP-seq
MIRT2516314	hsa-miR-3129-5p	CLIP-seq
MIRT2516315	hsa-miR-3130-3p	CLIP-seq
MIRT2516316	hsa-miR-3130-5p	CLIP-seq
MIRT2516318	hsa-miR-3136-3p	CLIP-seq
MIRT936604	hsa-miR-3150a-3p	CLIP-seq
MIRT2516321	hsa-miR-3157-5p	CLIP-seq
MIRT2516323	hsa-miR-3162-3p	CLIP-seq
MIRT2516251	hsa-miR-3164	CLIP-seq
MIRT2516324	hsa-miR-3173-3p	CLIP-seq
MIRT2516325	hsa-miR-3174	CLIP-seq
MIRT936605	hsa-miR-3175	CLIP-seq
MIRT2516326	hsa-miR-3181	CLIP-seq
MIRT2516327	hsa-miR-3182	CLIP-seq
MIRT2516328	hsa-miR-3184	CLIP-seq
MIRT2516331	hsa-miR-3200-3p	CLIP-seq
MIRT2516337	hsa-miR-340	CLIP-seq
MIRT2516339	hsa-miR-361-3p	CLIP-seq
MIRT2516340	hsa-miR-3614-3p	CLIP-seq
MIRT2516341	hsa-miR-3654	CLIP-seq
MIRT2516344	hsa-miR-3667-3p	CLIP-seq
MIRT2516345	hsa-miR-3671	CLIP-seq
MIRT2516346	hsa-miR-3677-5p	CLIP-seq
MIRT2516347	hsa-miR-374c	CLIP-seq
MIRT2516350	hsa-miR-381	CLIP-seq
MIRT2516352	hsa-miR-3914	CLIP-seq
MIRT2516355	hsa-miR-3926	CLIP-seq
MIRT2516356	hsa-miR-3938	CLIP-seq
MIRT2516357	hsa-miR-3944-3p	CLIP-seq
MIRT2516358	hsa-miR-3972	CLIP-seq
MIRT2212516	hsa-miR-3973	CLIP-seq
MIRT2516360	hsa-miR-3977	CLIP-seq
MIRT2516361	hsa-miR-412	CLIP-seq
MIRT2516362	hsa-miR-423-5p	CLIP-seq
MIRT2516364	hsa-miR-4254	CLIP-seq
MIRT2516365	hsa-miR-4270	CLIP-seq
MIRT2516368	hsa-miR-4279	CLIP-seq
MIRT2516369	hsa-miR-4287	CLIP-seq
MIRT2516371	hsa-miR-4297	CLIP-seq
MIRT2516372	hsa-miR-4299	CLIP-seq
MIRT936587	hsa-miR-4307	CLIP-seq
MIRT936611	hsa-miR-4426	CLIP-seq
MIRT2516378	hsa-miR-4428	CLIP-seq
MIRT2516252	hsa-miR-4434	CLIP-seq
MIRT2516379	hsa-miR-4436b-3p	CLIP-seq
MIRT2516380	hsa-miR-4441	CLIP-seq
MIRT2516381	hsa-miR-4449	CLIP-seq
MIRT2516383	hsa-miR-4456	CLIP-seq
MIRT2516386	hsa-miR-4469	CLIP-seq
MIRT936612	hsa-miR-4470	CLIP-seq
MIRT2516387	hsa-miR-4476	CLIP-seq
MIRT2516389	hsa-miR-4482	CLIP-seq
MIRT2516391	hsa-miR-4490	CLIP-seq
MIRT2516394	hsa-miR-4501	CLIP-seq
MIRT2516395	hsa-miR-4504	CLIP-seq
MIRT2516253	hsa-miR-4516	CLIP-seq
MIRT2516399	hsa-miR-4521	CLIP-seq
MIRT2516400	hsa-miR-4522	CLIP-seq
MIRT2516402	hsa-miR-4531	CLIP-seq
MIRT2516404	hsa-miR-4637	CLIP-seq
MIRT2516406	hsa-miR-4643	CLIP-seq
MIRT936614	hsa-miR-4647	CLIP-seq
MIRT2516408	hsa-miR-4659a-3p	CLIP-seq
MIRT2516409	hsa-miR-4659b-3p	CLIP-seq
MIRT2516410	hsa-miR-466	CLIP-seq
MIRT936615	hsa-miR-4662b	CLIP-seq
MIRT2212514	hsa-miR-4666-3p	CLIP-seq
MIRT2516411	hsa-miR-4674	CLIP-seq
MIRT2516416	hsa-miR-4685-3p	CLIP-seq
MIRT2516422	hsa-miR-4716-3p	CLIP-seq
MIRT2516423	hsa-miR-4723-5p	CLIP-seq
MIRT2516424	hsa-miR-4728-5p	CLIP-seq
MIRT2212518	hsa-miR-4729	CLIP-seq
MIRT2516425	hsa-miR-4737	CLIP-seq
MIRT2516427	hsa-miR-4750	CLIP-seq
MIRT2516428	hsa-miR-4755-3p	CLIP-seq
MIRT2516429	hsa-miR-4761-3p	CLIP-seq
MIRT2516430	hsa-miR-4762-5p	CLIP-seq
MIRT2516433	hsa-miR-4774-5p	CLIP-seq
MIRT2516435	hsa-miR-4785	CLIP-seq
MIRT2516436	hsa-miR-4786-5p	CLIP-seq
MIRT2516437	hsa-miR-4789-3p	CLIP-seq
MIRT2516438	hsa-miR-4789-5p	CLIP-seq
MIRT2516440	hsa-miR-4793-3p	CLIP-seq
MIRT2516441	hsa-miR-4793-5p	CLIP-seq
MIRT2516442	hsa-miR-4795-5p	CLIP-seq
MIRT2516447	hsa-miR-501-3p	CLIP-seq
MIRT2516448	hsa-miR-502-3p	CLIP-seq
MIRT2516255	hsa-miR-502-5p	CLIP-seq
MIRT2516449	hsa-miR-5047	CLIP-seq
MIRT2516451	hsa-miR-517b	CLIP-seq
MIRT2516452	hsa-miR-520d-5p	CLIP-seq
MIRT2516453	hsa-miR-524-5p	CLIP-seq
MIRT2516454	hsa-miR-526b	CLIP-seq
MIRT2516456	hsa-miR-543	CLIP-seq
MIRT2516457	hsa-miR-548a-3p	CLIP-seq
MIRT1977137	hsa-miR-548a-5p	CLIP-seq
MIRT1977138	hsa-miR-548ab	CLIP-seq
MIRT1977139	hsa-miR-548ak	CLIP-seq
MIRT1977140	hsa-miR-548b-5p	CLIP-seq
MIRT1977141	hsa-miR-548c-5p	CLIP-seq
MIRT1977142	hsa-miR-548d-5p	CLIP-seq
MIRT2516464	hsa-miR-548e	CLIP-seq
MIRT2516465	hsa-miR-548f	CLIP-seq
MIRT1977143	hsa-miR-548h	CLIP-seq
MIRT1977144	hsa-miR-548i	CLIP-seq
MIRT1977145	hsa-miR-548j	CLIP-seq
MIRT2516466	hsa-miR-548k	CLIP-seq
MIRT2516467	hsa-miR-548l	CLIP-seq
MIRT2516257	hsa-miR-548o	CLIP-seq
MIRT2516468	hsa-miR-548q	CLIP-seq
MIRT2516469	hsa-miR-548s	CLIP-seq
MIRT1977147	hsa-miR-548w	CLIP-seq
MIRT1977148	hsa-miR-548y	CLIP-seq
MIRT1977149	hsa-miR-559	CLIP-seq
MIRT2212519	hsa-miR-579	CLIP-seq
MIRT2516474	hsa-miR-607	CLIP-seq
MIRT2516476	hsa-miR-627	CLIP-seq
MIRT2212520	hsa-miR-629	CLIP-seq
MIRT2516478	hsa-miR-635	CLIP-seq
MIRT2516479	hsa-miR-642a	CLIP-seq
MIRT2516480	hsa-miR-655	CLIP-seq
MIRT2516258	hsa-miR-659	CLIP-seq
MIRT2516481	hsa-miR-663b	CLIP-seq
MIRT1556225	hsa-miR-668	CLIP-seq
MIRT2516482	hsa-miR-769-5p	CLIP-seq
MIRT2516483	hsa-miR-890	CLIP-seq
MIRT2516486	hsa-miR-9	CLIP-seq
MIRT2516487	hsa-miR-921	CLIP-seq
MIRT2516488	hsa-miR-924	CLIP-seq
MIRT2212521	hsa-miR-935	CLIP-seq
MIRT2516489	hsa-miR-936	CLIP-seq
MIRT936620	hsa-miR-939	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001514	Process	Selenocysteine incorporation	NAS	9837913
GO:0004800	Function	Thyroxine 5'-deiodinase activity	IBA
GO:0004800	Function	Thyroxine 5'-deiodinase activity	IDA	10403186, 11108274, 12586771, 19651899
GO:0004800	Function	Thyroxine 5'-deiodinase activity	IEA
GO:0004800	Function	Thyroxine 5'-deiodinase activity	TAS	9837913
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	11089566
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006590	Process	Thyroid hormone generation	IEA
GO:0006590	Process	Thyroid hormone generation	TAS	8755651, 9837913
GO:0008430	Function	Selenium binding	IC	9837913
GO:0008430	Function	Selenium binding	TAS	8755651
GO:0016020	Component	Membrane	IC	9837913
GO:0016020	Component	Membrane	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	19651899
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0033798	Function	Thyroxine 5-deiodinase activity	IDA	18566113
GO:0042403	Process	Thyroid hormone metabolic process	IBA
GO:0042403	Process	Thyroid hormone metabolic process	IDA	19651899
GO:0042403	Process	Thyroid hormone metabolic process	IEA
GO:0042404	Process	Thyroid hormone catabolic process	IDA	10403186, 11108274, 12586771
GO:0042446	Process	Hormone biosynthetic process	IEA
GO:0120162	Process	Positive regulation of cold-induced thermogenesis	ISS	11696583

Other IDs

• MIM: 601413
• HGNC: 2884
• e!Ensembl: ENSG00000211448

Protein

• UniProt ID: Q92813
• Protein name: Type II iodothyronine deiodinase (EC 1.21.99.4) (5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase)
• Protein function: Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:11108274, PubMed:10403186, PubMed:18821722). Catalyzes the deiodination of L-thyrox
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00837	T4_deiodinase	4 → 262	Iodothyronine deiodinase	Family

• Tissue specificity: TISSUE SPECIFICITY: Isoform 1 is expressed in the lung, trachea, kidney, heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain (PubMed:11165050, PubMed:8755651). Isoform 2 is expressed in the brain, heart, kidney and trachea
• Sequence:

  MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGL
  RCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASP
  ERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSF
  EVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAY
  LGGKGPFSYNLQEVRHWLEKNFSKRUKKTRLAG

• Sequence length: 273

Pathways

KEGG:

Hormone signaling
Thyroid hormone signaling pathway

Reactome:

Regulation of thyroid hormone activity

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, BASAL CELL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ENDOMETRIOSIS	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSIVE DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Levothyroxine response	other	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MESOTHELIOMA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROLIFERATIVE DIABETIC RETINOPATHY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
THYROID DISEASES	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenomatous Polyposis Coli	Multiple polyposis syndrome	BEFREE	31215118		★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	31570705		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	31570705		★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	33449341	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autism Spectrum Disorders	Autism Spectrum Disorder	CTD_human_DG	24781735		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autoimmune Diseases	Autoimmune Diseases	BEFREE	23013882		★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	BEFREE	19427350		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar Disorder	PSYGENET_DG	19427350		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bone Diseases	Bone disease	Pubtator	35412619	Associate	★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain Neoplasms	BEFREE	11095486		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	36077333	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	26199857, 37059745	Associate	★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Cardiomyopathy	BEFREE	19684474		★☆☆☆☆ Found in Text Mining only
Cartilage Diseases	Cartilage disease	Pubtator	35412619	Associate	★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Cerebral Infarction	BEFREE	30366665		★☆☆☆☆ Found in Text Mining only
Choriocarcinoma	Choriocarcinoma	LHGDN	15291742		★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	30978267		★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognition disorder	Pubtator	33449341	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	31215118		★☆☆☆☆ Found in Text Mining only
Congenital Hypothyroidism	Congenital hypothyroidism	Pubtator	15286152	Associate	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	BEFREE	29641285		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	18334578, 18698177, 20090528, 20707788, 21400473, 22492780, 23296253, 24695009		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	LHGDN	18334578		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	29367100		★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	17381351		★☆☆☆☆ Found in Text Mining only
Diabetes Gestational	Gestational diabetes	Pubtator	33232364	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	17381351, 29641285		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	20930717, 22142372, 25105294, 35739305	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	LHGDN	15797963		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	16356084, 17077128, 17381351, 22142372, 25105294, 27777960, 31504428		★☆☆☆☆ Found in Text Mining only
Differentiated Thyroid Gland Carcinoma	Thyroid Carcinoma	BEFREE	24910925		★☆☆☆☆ Found in Text Mining only
Dystrophia myotonica 2	Myotonic dystrophy	BEFREE	17381351, 20566590		★☆☆☆☆ Found in Text Mining only
Endemic Cretinism	Endemic Cretinism	BEFREE	15911145		★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	35205233	Associate	★☆☆☆☆ Found in Text Mining only
Endometrioma	Endometrioma	CTD_human_DG	21063030		★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	CTD_human_DG	21063030		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Follicular thyroid carcinoma	Follicular Thyroid Carcinoma	BEFREE	15943828		★☆☆☆☆ Found in Text Mining only
Gaucher Disease	Gaucher disease	Pubtator	33049131	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	31452060		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	31452060		★☆☆☆☆ Found in Text Mining only
Graves Disease	Graves Disease	BEFREE	15542398, 19684474, 23109646, 30574458, 30610492		★☆☆☆☆ Found in Text Mining only
Graves Disease	Graves disease	Pubtator	23193417, 33049131	Associate	★☆☆☆☆ Found in Text Mining only
Hashimoto Disease	Hashimoto Disease	BEFREE	29648895		★☆☆☆☆ Found in Text Mining only
Hepatitis Chronic	Hepatitis	Pubtator	37059745	Associate	★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	31176677		★☆☆☆☆ Found in Text Mining only
Hyperinsulinism	Hyperinsulinism	BEFREE	25105294		★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	35739305, 36646987	Associate	★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	17224473, 29641285, 30063552		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertensive disease	Hypertension	LHGDN	17224473		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hyperthyroidism	Hyperthyroidism	BEFREE	29565584, 30610492, 30747053		★☆☆☆☆ Found in Text Mining only
Hypothyroidism	Hypothyroidism	BEFREE	19190113, 19293265, 22548953, 23329579, 26416219, 30063552, 30352046, 30508752, 30747053, 30817317, 30951174, 31617166		★☆☆☆☆ Found in Text Mining only
Hypothyroidism	Hypothyroidism	Pubtator	29321381, 29973617, 36646987	Associate	★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	29200204		★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Idiopathic pulmonary fibrosis	Pubtator	36681777	Associate	★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	18198294, 20930717, 25105294, 35739305	Associate	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	15286152, 22048657, 30423129		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	LHGDN	15286152		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	15286152	Associate	★☆☆☆☆ Found in Text Mining only
Intestinal Neoplasms	Intestinal Neoplasms	BEFREE	31215118		★☆☆☆☆ Found in Text Mining only
Kashin-Beck Disease	Kashin-Beck Disease	BEFREE	24058403, 25072641, 27256326, 31433532		★☆☆☆☆ Found in Text Mining only
Lipoatrophy	Lipoatrophy	BEFREE	20373986		★☆☆☆☆ Found in Text Mining only
Lipodystrophy	Lipodystrophy	BEFREE	20373986		★☆☆☆☆ Found in Text Mining only
Lipodystrophy Familial Partial	Lipodystrophy	Pubtator	20373986	Associate	★☆☆☆☆ Found in Text Mining only
Liver Cirrhosis	Liver cirrhosis	Pubtator	37059745	Associate	★☆☆☆☆ Found in Text Mining only
Liver Diseases	Liver disease	Pubtator	37059745	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	30742096		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31215118		★☆☆☆☆ Found in Text Mining only
Mental Retardation	Mental retardation	BEFREE	15286152, 22048657		★☆☆☆☆ Found in Text Mining only
Mesothelioma	Mesothelioma	CTD_human_DG	11425850		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Metabolic Syndrome	Metabolic syndrome	Pubtator	18198294, 20930717	Associate	★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	18198294, 27786042		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	33449341	Associate	★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	26416219, 29481662		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	11872697, 17077128, 22142372, 23329579, 30116736, 31570705		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	22142372, 25622596, 30116736	Associate	★☆☆☆☆ Found in Text Mining only
Obesity Morbid	Obesity	Pubtator	35739305	Associate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	21400473, 24695009, 24825461, 33455417	Associate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis Hip	Osteoarthritis	Pubtator	21400473	Associate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis of hip	Osteoarthritis Of Hip	BEFREE	18334578, 21400473		★☆☆☆☆ Found in Text Mining only
Papillary thyroid carcinoma	Papillary thyroid carcinoma	BEFREE	15785240, 19208736, 22823995		★☆☆☆☆ Found in Text Mining only
Pendred syndrome	Pendred syndrome	Pubtator	17940114	Associate	★☆☆☆☆ Found in Text Mining only
Pituitary Neoplasms	Pituitary Neoplasms	LHGDN	12153750		★☆☆☆☆ Found in Text Mining only
Polyostotic fibrous dysplasia	Polyostotic Fibrous Dysplasia	LHGDN	18349068		★☆☆☆☆ Found in Text Mining only
POPLITEAL PTERYGIUM SYNDROME, LETHAL TYPE	Bartsocas-Papas syndrome	BEFREE	28467477		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	30742096		★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	30978267	Stimulate	★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	29200204		★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary fibrosis	Pubtator	35137147	Associate	★☆☆☆☆ Found in Text Mining only
Recurrent depression	Mental Depression	BEFREE	26098717		★☆☆☆☆ Found in Text Mining only
Recurrent depressive disorder	Mental Depression	BEFREE	26098717		★☆☆☆☆ Found in Text Mining only
Status Epilepticus	Status Epilepticus	BEFREE	29905787		★☆☆☆☆ Found in Text Mining only
Thyroid associated opthalmopathies	Thyroid eye disease	BEFREE	30574458		★☆☆☆☆ Found in Text Mining only
Thyroid cancer medullary	Medullary thyroid cancer	Pubtator	18514391	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Cancer Papillary	Papillary thyroid cancer	Pubtator	39408960	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Diseases	Thyroid Diseases	CTD_human_DG	23397585		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid Diseases	Thyroid Diseases	BEFREE	29648895		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid Gland Follicular Adenoma	Thyroid Gland Follicular Adenoma	BEFREE	10614643		★☆☆☆☆ Found in Text Mining only
Thyroid Hormone Metabolism Abnormal	Thyroid hormone metabolism disorder	Pubtator	29973617	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Hormone Metabolism, Abnormal	Thyroid Hormone Metabolism	BEFREE	29973617		★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasm	Thyroid Neoplasm	BEFREE	15785240		★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasm	Thyroid Neoplasm	LHGDN	18514391		★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	24910925	Associate	★☆☆☆☆ Found in Text Mining only