Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	171483
Gene name	Family with sequence similarity 9 member B
Gene symbol	FAM9B
Synonyms (NCBI Gene)	TEX39B
Chromosome	X
Chromosome location	Xp22.31
Summary	This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be localized to the nucleus as the protein contains several nuclear localization signals, and has similarity to a synaptonemal complex prot

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021936	hsa-miR-128-3p	Microarray	17612493
MIRT637332	hsa-miR-1245a	HITS-CLIP	23824327
MIRT637331	hsa-miR-8079	HITS-CLIP	23824327
MIRT637330	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT637329	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT637328	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT637327	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT637326	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT637325	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT637324	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT637323	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT637322	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT637321	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679205	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT637320	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637319	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679204	hsa-miR-6131	HITS-CLIP	23824327
MIRT637318	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT637317	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637316	hsa-miR-640	HITS-CLIP	23824327
MIRT679203	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679202	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT637332	hsa-miR-1245a	HITS-CLIP	23824327
MIRT637331	hsa-miR-8079	HITS-CLIP	23824327
MIRT637330	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT637329	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT637328	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT637327	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT637326	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT637325	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT637324	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT637323	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT637322	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT637321	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT637320	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637319	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637318	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT637317	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637316	hsa-miR-640	HITS-CLIP	23824327
MIRT637332	hsa-miR-1245a	HITS-CLIP	23824327
MIRT637331	hsa-miR-8079	HITS-CLIP	23824327
MIRT637330	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT637329	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT637328	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT637327	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT637326	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT637325	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT637324	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT637323	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT637322	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT637321	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679205	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT637320	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637319	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679204	hsa-miR-6131	HITS-CLIP	23824327
MIRT637318	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT637317	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637316	hsa-miR-640	HITS-CLIP	23824327
MIRT679203	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679202	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT637332	hsa-miR-1245a	HITS-CLIP	23824327
MIRT637331	hsa-miR-8079	HITS-CLIP	23824327
MIRT637330	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT637329	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT637328	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT637327	hsa-miR-6795-3p	HITS-CLIP	23824327
MIRT637326	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT637325	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT637324	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT637323	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT637322	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT637321	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT637320	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637319	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637318	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT637317	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637316	hsa-miR-640	HITS-CLIP	23824327
MIRT2449461	hsa-miR-3926	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000795	Component	Synaptonemal complex	IBA
GO:0005515	Function	Protein binding	IPI	24722188, 25416956, 25910212, 26871637, 31515488, 32296183, 33961781
GO:0005634	Component	Nucleus	IDA	34507348
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IDA	34507348
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IDA	34507348
GO:0005737	Component	Cytoplasm	IEA
GO:0007286	Process	Spermatid development	IBA
GO:0051321	Process	Meiotic cell cycle	IBA
GO:0051321	Process	Meiotic cell cycle	IEA

MIM	HGNC	e!Ensembl
300478	18404	ENSG00000177138

Q8IZU0

Protein name

Protein FAM9B

Protein function

May play a role in meiosis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04803	Cor1	61 → 186	Cor1/Xlr/Xmr conserved region	Coiled-coil

Tissue specificity

TISSUE SPECIFICITY: Expressed in testis and ovary (at protein level). {ECO:0000269|PubMed:34507348}.

Sequence

MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA
EDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE
EEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE
DSELDN

Sequence length

186

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DERMATOPHYTOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Azoospermia Nonobstructive	Nonobstructive azoospermia	Pubtator	36017582	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

FAM9B (family with sequence similarity 9 member B)