TXLNB (taxilin beta)

Gene

• Entrez ID: 167838
• Gene name: Taxilin beta
• Gene symbol: TXLNB
• Synonyms (NCBI Gene): C6orf198, LST001, MDP77, dJ522B19.2
• Chromosome: 6
• Chromosome location: 6q24.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT619519	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT619518	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT619517	hsa-miR-3183	HITS-CLIP	23824327
MIRT619516	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT619515	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT619514	hsa-miR-1266-3p	HITS-CLIP	23824327
MIRT619513	hsa-miR-4469	HITS-CLIP	23824327
MIRT619512	hsa-miR-4287	HITS-CLIP	23824327
MIRT619511	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT619510	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619509	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619508	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619507	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT619506	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT619505	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT619504	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT619503	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT619502	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT619501	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT619500	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT619499	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT619498	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619497	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT619496	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT619495	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT619494	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT619493	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT619519	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT619518	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT619517	hsa-miR-3183	HITS-CLIP	23824327
MIRT619516	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT619515	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT619514	hsa-miR-1266-3p	HITS-CLIP	23824327
MIRT619513	hsa-miR-4469	HITS-CLIP	23824327
MIRT619512	hsa-miR-4287	HITS-CLIP	23824327
MIRT619511	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT619510	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT619509	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619508	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619507	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT619506	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT619505	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT619504	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT619503	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT619502	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT619501	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT619500	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT619499	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT619498	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619497	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT619496	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT619495	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT619494	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT619493	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT1464723	hsa-miR-1255a	CLIP-seq
MIRT1464724	hsa-miR-1255b	CLIP-seq
MIRT1464725	hsa-miR-129-5p	CLIP-seq
MIRT1464726	hsa-miR-130a	CLIP-seq
MIRT1464727	hsa-miR-130b	CLIP-seq
MIRT1464728	hsa-miR-199a-5p	CLIP-seq
MIRT1464729	hsa-miR-199b-5p	CLIP-seq
MIRT1464730	hsa-miR-2052	CLIP-seq
MIRT1464731	hsa-miR-301a	CLIP-seq
MIRT1464732	hsa-miR-301b	CLIP-seq
MIRT1464733	hsa-miR-3148	CLIP-seq
MIRT1464734	hsa-miR-3647-3p	CLIP-seq
MIRT1464735	hsa-miR-3666	CLIP-seq
MIRT1464736	hsa-miR-3935	CLIP-seq
MIRT1464737	hsa-miR-3940-5p	CLIP-seq
MIRT1464738	hsa-miR-3978	CLIP-seq
MIRT1464739	hsa-miR-4280	CLIP-seq
MIRT1464740	hsa-miR-4295	CLIP-seq
MIRT1464741	hsa-miR-4474-5p	CLIP-seq
MIRT1464742	hsa-miR-4507	CLIP-seq
MIRT1464743	hsa-miR-454	CLIP-seq
MIRT1464744	hsa-miR-4799-5p	CLIP-seq
MIRT1464745	hsa-miR-495	CLIP-seq
MIRT1464746	hsa-miR-513c	CLIP-seq
MIRT1464747	hsa-miR-514b-5p	CLIP-seq
MIRT1464748	hsa-miR-519a	CLIP-seq
MIRT1464749	hsa-miR-519b-3p	CLIP-seq
MIRT1464750	hsa-miR-519c-3p	CLIP-seq
MIRT1464751	hsa-miR-599	CLIP-seq
MIRT2139828	hsa-miR-204	CLIP-seq
MIRT2139829	hsa-miR-211	CLIP-seq
MIRT2139830	hsa-miR-4659a-3p	CLIP-seq
MIRT2139831	hsa-miR-4659b-3p	CLIP-seq
MIRT2139832	hsa-miR-4755-5p	CLIP-seq
MIRT2139833	hsa-miR-623	CLIP-seq
MIRT2360381	hsa-miR-1208	CLIP-seq
MIRT2360382	hsa-miR-3140-3p	CLIP-seq
MIRT2360383	hsa-miR-3671	CLIP-seq
MIRT2360384	hsa-miR-4428	CLIP-seq
MIRT2360385	hsa-miR-4662a-3p	CLIP-seq
MIRT2360386	hsa-miR-498	CLIP-seq
MIRT2360387	hsa-miR-607	CLIP-seq
MIRT2653737	hsa-miR-1184	CLIP-seq
MIRT2653738	hsa-miR-1205	CLIP-seq
MIRT2653739	hsa-miR-1207-5p	CLIP-seq
MIRT2653740	hsa-miR-1253	CLIP-seq
MIRT1464723	hsa-miR-1255a	CLIP-seq
MIRT1464724	hsa-miR-1255b	CLIP-seq
MIRT1464726	hsa-miR-130a	CLIP-seq
MIRT1464727	hsa-miR-130b	CLIP-seq
MIRT2653741	hsa-miR-1343	CLIP-seq
MIRT2653742	hsa-miR-136	CLIP-seq
MIRT2653743	hsa-miR-143	CLIP-seq
MIRT2653744	hsa-miR-1587	CLIP-seq
MIRT2653745	hsa-miR-1827	CLIP-seq
MIRT2653746	hsa-miR-1909	CLIP-seq
MIRT2653747	hsa-miR-1911	CLIP-seq
MIRT2653748	hsa-miR-2277-3p	CLIP-seq
MIRT2653749	hsa-miR-28-3p	CLIP-seq
MIRT1464731	hsa-miR-301a	CLIP-seq
MIRT1464732	hsa-miR-301b	CLIP-seq
MIRT2653750	hsa-miR-3120-3p	CLIP-seq
MIRT2653751	hsa-miR-3123	CLIP-seq
MIRT2653752	hsa-miR-3145-5p	CLIP-seq
MIRT2653753	hsa-miR-3158-5p	CLIP-seq
MIRT2653754	hsa-miR-3184	CLIP-seq
MIRT2653755	hsa-miR-3185	CLIP-seq
MIRT2653756	hsa-miR-330-3p	CLIP-seq
MIRT1464735	hsa-miR-3666	CLIP-seq
MIRT2653757	hsa-miR-3672	CLIP-seq
MIRT2653758	hsa-miR-3688-5p	CLIP-seq
MIRT2653759	hsa-miR-3690	CLIP-seq
MIRT2653760	hsa-miR-3908	CLIP-seq
MIRT2653761	hsa-miR-3925-5p	CLIP-seq
MIRT2653762	hsa-miR-423-5p	CLIP-seq
MIRT2653763	hsa-miR-4251	CLIP-seq
MIRT2653764	hsa-miR-4254	CLIP-seq
MIRT1464739	hsa-miR-4280	CLIP-seq
MIRT1464740	hsa-miR-4295	CLIP-seq
MIRT2653765	hsa-miR-431	CLIP-seq
MIRT2653766	hsa-miR-432	CLIP-seq
MIRT2653767	hsa-miR-4434	CLIP-seq
MIRT2653768	hsa-miR-4470	CLIP-seq
MIRT2653769	hsa-miR-4492	CLIP-seq
MIRT2653770	hsa-miR-4498	CLIP-seq
MIRT2653771	hsa-miR-4516	CLIP-seq
MIRT2653772	hsa-miR-451b	CLIP-seq
MIRT1464743	hsa-miR-454	CLIP-seq
MIRT2653773	hsa-miR-4651	CLIP-seq
MIRT2653774	hsa-miR-4652-3p	CLIP-seq
MIRT2653775	hsa-miR-4656	CLIP-seq
MIRT2653776	hsa-miR-4660	CLIP-seq
MIRT2653777	hsa-miR-4671-3p	CLIP-seq
MIRT2653778	hsa-miR-4675	CLIP-seq
MIRT2653779	hsa-miR-4696	CLIP-seq
MIRT2653780	hsa-miR-4709-3p	CLIP-seq
MIRT2653781	hsa-miR-4727-5p	CLIP-seq
MIRT2653782	hsa-miR-4741	CLIP-seq
MIRT2653783	hsa-miR-4763-3p	CLIP-seq
MIRT2653784	hsa-miR-4768-5p	CLIP-seq
MIRT2653785	hsa-miR-4770	CLIP-seq
MIRT2653786	hsa-miR-4790-3p	CLIP-seq
MIRT2653787	hsa-miR-4792	CLIP-seq
MIRT2653788	hsa-miR-4804-5p	CLIP-seq
MIRT2653789	hsa-miR-508-5p	CLIP-seq
MIRT2653790	hsa-miR-526b	CLIP-seq
MIRT2653791	hsa-miR-550b	CLIP-seq
MIRT2653792	hsa-miR-581	CLIP-seq
MIRT2653793	hsa-miR-608	CLIP-seq
MIRT2653794	hsa-miR-646	CLIP-seq
MIRT2653795	hsa-miR-654-3p	CLIP-seq
MIRT2653796	hsa-miR-656	CLIP-seq
MIRT2653797	hsa-miR-762	CLIP-seq
MIRT2653798	hsa-miR-940	CLIP-seq
MIRT2694528	hsa-miR-1200	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21903422, 25416956, 28514442, 29892012, 31515488, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IDA
GO:0019905	Function	Syntaxin binding	IEA

Other IDs

• MIM: 611438
• HGNC: 21617
• e!Ensembl: ENSG00000164440

Protein

• UniProt ID: Q8N3L3
• Protein name: Beta-taxilin (Muscle-derived protein 77) (hMDP77)
• Protein function: Promotes motor nerve regeneration (By similarity). May be involved in intracellular vesicle traffic.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF09728	Taxilin	143 → 450	Myosin-like coiled-coil protein	Coiled-coil

• Tissue specificity: TISSUE SPECIFICITY: Expressed in skeletal muscle.
• Sequence:

  MEANHSEQLSAERQSTPPGDSSSLPSHNGLEKEDGQDSPTPVQPPEKEASVHPDISEELN
  RQLEDIINTYGSAASTAGKEGSARASEQPENAESPDNEDGDCEETTEEAGREPVASGEPP
  TVKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQ
  KKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEEALQRAREEE
  EKRKEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIF
  KHRELQQKLVDAKLEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQETVLQAQL
  TLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMI
  EEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDDQSQHNSDEEPES
  NVSVDQEIDAEEVNSVQTAVKNLATAFMIIHHPESTPHQSKETQPEIGSSQESADAALKE
  PEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQAD
  QASWKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEEHVAAMVPACEPSRQPPRAAAE
  ELPVGASAGPQPRNVADTNLEGVD

• Sequence length: 684

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations