Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	165186
Gene name	TOG array regulator of axonemal microtubules 2
Gene symbol	TOGARAM2
Synonyms (NCBI Gene)	FAM179A
Chromosome	2
Chromosome location	2p23.2

111

Show/Hide all (111)

miRTarBase ID	miRNA	Experiments	Reference
MIRT713404	hsa-miR-548n	HITS-CLIP	19536157
MIRT713403	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT713402	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT713401	hsa-miR-6871-3p	HITS-CLIP	19536157
MIRT713399	hsa-miR-7108-3p	HITS-CLIP	19536157
MIRT713404	hsa-miR-548n	HITS-CLIP	19536157
MIRT713403	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT713402	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT713401	hsa-miR-6871-3p	HITS-CLIP	19536157
MIRT713400	hsa-miR-3065-3p	HITS-CLIP	19536157
MIRT713399	hsa-miR-7108-3p	HITS-CLIP	19536157
MIRT613062	hsa-miR-8485	HITS-CLIP	23313552
MIRT671579	hsa-miR-3692-3p	HITS-CLIP	23313552
MIRT613062	hsa-miR-8485	HITS-CLIP	23313552
MIRT671579	hsa-miR-3692-3p	HITS-CLIP	23313552
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT671581	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT671580	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT671579	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT635316	hsa-miR-4428	HITS-CLIP	23824327
MIRT635315	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT635314	hsa-miR-4457	HITS-CLIP	23824327
MIRT635313	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT635312	hsa-miR-6884-3p	HITS-CLIP	23824327
MIRT635311	hsa-miR-1470	HITS-CLIP	23824327
MIRT635310	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT635309	hsa-miR-4469	HITS-CLIP	23824327
MIRT635308	hsa-miR-296-5p	HITS-CLIP	23824327
MIRT635307	hsa-miR-513b-5p	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT523817	hsa-miR-1179	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT613062	hsa-miR-8485	HITS-CLIP	23824327
MIRT613061	hsa-miR-621	HITS-CLIP	23824327
MIRT528009	hsa-miR-3662	PAR-CLIP	22012620
MIRT528008	hsa-miR-4802-3p	PAR-CLIP	22012620
MIRT528007	hsa-miR-7845-5p	PAR-CLIP	22012620
MIRT528006	hsa-miR-1272	PAR-CLIP	22012620
MIRT528005	hsa-miR-4698	PAR-CLIP	22012620
MIRT528004	hsa-miR-3121-5p	PAR-CLIP	22012620
MIRT528003	hsa-miR-1206	PAR-CLIP	22012620
MIRT528002	hsa-miR-6516-3p	PAR-CLIP	22012620
MIRT528001	hsa-miR-135b-3p	PAR-CLIP	22012620
MIRT528000	hsa-miR-3674	PAR-CLIP	22012620
MIRT523819	hsa-miR-3646	PAR-CLIP	23446348
MIRT523818	hsa-miR-1252-3p	PAR-CLIP	23446348
MIRT523817	hsa-miR-1179	PAR-CLIP	23446348
MIRT523816	hsa-miR-6888-5p	PAR-CLIP	23446348
MIRT523815	hsa-miR-875-5p	PAR-CLIP	23446348
MIRT523814	hsa-miR-4266	PAR-CLIP	23446348
MIRT523813	hsa-miR-3144-3p	PAR-CLIP	23446348
MIRT495033	hsa-miR-1913	PAR-CLIP	22291592
MIRT495032	hsa-miR-324-3p	PAR-CLIP	22291592
MIRT495031	hsa-miR-18a-3p	PAR-CLIP	22291592
MIRT495030	hsa-miR-5189-3p	PAR-CLIP	22291592
MIRT495029	hsa-miR-4727-5p	PAR-CLIP	22291592
MIRT495028	hsa-miR-5001-3p	PAR-CLIP	22291592
MIRT495027	hsa-miR-6738-3p	PAR-CLIP	22291592
MIRT495033	hsa-miR-1913	PAR-CLIP	23708386
MIRT495032	hsa-miR-324-3p	PAR-CLIP	23708386
MIRT495031	hsa-miR-18a-3p	PAR-CLIP	23708386
MIRT495030	hsa-miR-5189-3p	PAR-CLIP	23708386
MIRT495029	hsa-miR-4727-5p	PAR-CLIP	23708386
MIRT495028	hsa-miR-5001-3p	PAR-CLIP	23708386
MIRT495027	hsa-miR-6738-3p	PAR-CLIP	23708386

Show/Hide all (8)

GO ID	Ontology	Definition	Evidence
GO:0000226	Process	Microtubule cytoskeleton organization	IBA
GO:0005881	Component	Cytoplasmic microtubule	IBA
GO:0005929	Component	Cilium	IBA
GO:0008017	Function	Microtubule binding	IBA
GO:0008017	Function	Microtubule binding	IEA
GO:0015630	Component	Microtubule cytoskeleton	IEA
GO:0051494	Process	Negative regulation of cytoskeleton organization	IEA
GO:1902904	Process	Negative regulation of supramolecular fiber organization	IEA

MIM	HGNC	e!Ensembl
620949	33715	ENSG00000189350

Q6ZUX3

Protein name

TOG array regulator of axonemal microtubules protein 2 (Crescerin-2)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12348	CLASP_N	492 → 689	CLASP N terminal	Family

Sequence

MGTRDDVPEAKVLVPVAVYCGSIPRTSAGPRVLPPGSINSSLPHGEGSLQPEPRALLNNE
EPSQLLRGLGQLGGLKLDTPSKGWQARNGHPRNLRALSLGDQPLVLLPSPESEANSVARD
TIQIKDKLKKRRLSEGLAASSRASLDPGGGPQGVPLHSTIPRATSQRLLRVPRPMPLIQS
IPTTPEASGVKEKGLDLPGSIPGPHELRPGAQEAQISWQYLHCNDEKMQKSLGAIVIPPI
PKARTVAATPSRVPGSLPSPLPPGQGVLTGLRAPRTRLARGSGPREKTPASLEPKPLASP
IRDRPAAAKKPALPFSQSAPTLTAFSFDCAREACPPLKEEDQKEIGTKIQVTISKSAREK
MQLKQMKEMELLRRLEEPRTGQELTSQCLGSQRAFMKEGLLPLRGSGTLSVPTRLSGPCR
NDVSIILRKWASRASLPSIPISRQEPRFARHASANSLPAVLTLGSPEWEEEEEMDLRACK
ELRPFSNPELGLRDALQCLNSSDWQMKEKGLVSIQRLAACHSEVLTGKLHDVCLVVTGEV
TNLRSKVSHLAISTLGDLFQALKKNMDQEAEEIARCLLQKMADTNEFIQRAAGQSLRAMV
ENVTLARSLVVLTSAGVYHRNPLIRKYAAEHLSAVLEQIGAEKLLSGTRDSTDMLVHNLV
RLAQDSNQDTRFYGRKMVNILMANTKFDAFLKQSLPSYDLQKVMAAIKQQGIEDNDELPS
AKGRKVLRSLVVCENGLPIKEGLSCNGPRLVGLRSTLQGRGEMVEQLRELTRLLEAKDFR
SRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPRLQDSNKKVNQWALESFAKMIPLLRES
LHPMLLSIIITVADNLNSKNSGIYAAAVAVLDAMVESLDNLCLLPALAGRVRFLSGRAVL
DVTDRLAVLVASVYPRKPQAVERHVLPILWHFLNTATRNGTLPGPSGNIRGVVCRLSRSL
QEHMGSRLLDFAASQPKHVLKTLQELLDSESLGGSRKATDRGVAPDSKTTGSSYPFQLD

Sequence length

1019

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DEAFNESS, AUTOSOMAL RECESSIVE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EOSINOPHILIC ESOPHAGITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hearing loss, autosomal recessive	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Narcolepsy	Narcolepsy	GWASDB_DG	19629137		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	33450964	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

TOGARAM2 (TOG array regulator of axonemal microtubules 2)