Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	163782
Gene name	KN motif and ankyrin repeat domains 4
Gene symbol	KANK4
Synonyms (NCBI Gene)	ANKRD38dJ1078M7.1
Chromosome	1
Chromosome location	1p31.3

308

Show/Hide all (308)

miRTarBase ID	miRNA	Experiments	Reference
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT628088	hsa-miR-3936	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT628088	hsa-miR-3936	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT530155	hsa-miR-1207-3p	PAR-CLIP	22012620
MIRT530154	hsa-miR-6884-3p	PAR-CLIP	22012620
MIRT530153	hsa-miR-4738-3p	PAR-CLIP	22012620
MIRT530152	hsa-miR-103a-2-5p	PAR-CLIP	22012620
MIRT530151	hsa-miR-1290	PAR-CLIP	22012620
MIRT530150	hsa-miR-510-3p	PAR-CLIP	22012620
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT628088	hsa-miR-3936	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT628088	hsa-miR-3936	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT616260	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616259	hsa-miR-6085	HITS-CLIP	23824327
MIRT616258	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT616257	hsa-miR-3119	HITS-CLIP	23824327
MIRT616256	hsa-miR-153-3p	HITS-CLIP	23824327
MIRT616255	hsa-miR-448	HITS-CLIP	23824327
MIRT616254	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT616253	hsa-miR-507	HITS-CLIP	23824327
MIRT616252	hsa-miR-557	HITS-CLIP	23824327
MIRT616251	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT530155	hsa-miR-1207-3p	PAR-CLIP	22012620
MIRT530154	hsa-miR-6884-3p	PAR-CLIP	22012620
MIRT530153	hsa-miR-4738-3p	PAR-CLIP	22012620
MIRT530152	hsa-miR-103a-2-5p	PAR-CLIP	22012620
MIRT530151	hsa-miR-1290	PAR-CLIP	22012620
MIRT530150	hsa-miR-510-3p	PAR-CLIP	22012620
MIRT1078580	hsa-miR-1182	CLIP-seq
MIRT1078581	hsa-miR-125a-3p	CLIP-seq
MIRT1078582	hsa-miR-3663-5p	CLIP-seq
MIRT1078583	hsa-miR-3672	CLIP-seq
MIRT1078584	hsa-miR-371-5p	CLIP-seq
MIRT1078585	hsa-miR-371b-5p	CLIP-seq
MIRT1078586	hsa-miR-3934	CLIP-seq
MIRT1078587	hsa-miR-4659a-3p	CLIP-seq
MIRT1078588	hsa-miR-4659b-3p	CLIP-seq
MIRT1078589	hsa-miR-4797-5p	CLIP-seq
MIRT1078590	hsa-miR-640	CLIP-seq
MIRT1078591	hsa-miR-764	CLIP-seq
MIRT2019553	hsa-miR-103a	CLIP-seq
MIRT2019554	hsa-miR-107	CLIP-seq
MIRT2019555	hsa-miR-122	CLIP-seq
MIRT2019556	hsa-miR-1281	CLIP-seq
MIRT2019557	hsa-miR-1297	CLIP-seq
MIRT2019558	hsa-miR-1307	CLIP-seq
MIRT2019559	hsa-miR-130a	CLIP-seq
MIRT2019560	hsa-miR-130b	CLIP-seq
MIRT2019561	hsa-miR-153	CLIP-seq
MIRT2019562	hsa-miR-183	CLIP-seq
MIRT2019563	hsa-miR-1912	CLIP-seq
MIRT2019564	hsa-miR-1976	CLIP-seq
MIRT2019565	hsa-miR-26a	CLIP-seq
MIRT2019566	hsa-miR-26b	CLIP-seq
MIRT2019567	hsa-miR-301a	CLIP-seq
MIRT2019568	hsa-miR-301b	CLIP-seq
MIRT2019569	hsa-miR-3065-3p	CLIP-seq
MIRT2019570	hsa-miR-3130-5p	CLIP-seq
MIRT2019571	hsa-miR-3135b	CLIP-seq
MIRT2019572	hsa-miR-3174	CLIP-seq
MIRT2019573	hsa-miR-3652	CLIP-seq
MIRT2019574	hsa-miR-3666	CLIP-seq
MIRT2019575	hsa-miR-3935	CLIP-seq
MIRT2019576	hsa-miR-410	CLIP-seq
MIRT2019577	hsa-miR-4284	CLIP-seq
MIRT2019578	hsa-miR-4295	CLIP-seq
MIRT2019579	hsa-miR-4430	CLIP-seq
MIRT2019580	hsa-miR-4465	CLIP-seq
MIRT2019581	hsa-miR-4482	CLIP-seq
MIRT2019582	hsa-miR-4532	CLIP-seq
MIRT2019583	hsa-miR-454	CLIP-seq
MIRT2019584	hsa-miR-4638-5p	CLIP-seq
MIRT1078587	hsa-miR-4659a-3p	CLIP-seq
MIRT1078588	hsa-miR-4659b-3p	CLIP-seq
MIRT2019585	hsa-miR-4718	CLIP-seq
MIRT2019586	hsa-miR-4722-3p	CLIP-seq
MIRT2019587	hsa-miR-564	CLIP-seq
MIRT2019588	hsa-miR-627	CLIP-seq
MIRT2019589	hsa-miR-924	CLIP-seq
MIRT2251441	hsa-miR-106a	CLIP-seq
MIRT2251442	hsa-miR-106b	CLIP-seq
MIRT2251443	hsa-miR-1234	CLIP-seq
MIRT1078581	hsa-miR-125a-3p	CLIP-seq
MIRT2251444	hsa-miR-150	CLIP-seq
MIRT2251445	hsa-miR-17	CLIP-seq
MIRT2251446	hsa-miR-197	CLIP-seq
MIRT2251447	hsa-miR-20a	CLIP-seq
MIRT2251448	hsa-miR-20b	CLIP-seq
MIRT2251449	hsa-miR-302a	CLIP-seq
MIRT2251450	hsa-miR-302b	CLIP-seq
MIRT2251451	hsa-miR-302c	CLIP-seq
MIRT2251452	hsa-miR-302d	CLIP-seq
MIRT2251453	hsa-miR-302e	CLIP-seq
MIRT2251454	hsa-miR-3194-3p	CLIP-seq
MIRT1078584	hsa-miR-371-5p	CLIP-seq
MIRT1078585	hsa-miR-371b-5p	CLIP-seq
MIRT2251455	hsa-miR-372	CLIP-seq
MIRT2251456	hsa-miR-373	CLIP-seq
MIRT1078586	hsa-miR-3934	CLIP-seq
MIRT1078587	hsa-miR-4659a-3p	CLIP-seq
MIRT1078588	hsa-miR-4659b-3p	CLIP-seq
MIRT2251457	hsa-miR-4786-3p	CLIP-seq
MIRT2251458	hsa-miR-519d	CLIP-seq
MIRT2251459	hsa-miR-520a-3p	CLIP-seq
MIRT2251460	hsa-miR-520b	CLIP-seq
MIRT2251461	hsa-miR-520c-3p	CLIP-seq
MIRT2251462	hsa-miR-520d-3p	CLIP-seq
MIRT2251463	hsa-miR-520e	CLIP-seq
MIRT2251464	hsa-miR-520g	CLIP-seq
MIRT2251465	hsa-miR-520h	CLIP-seq
MIRT1078590	hsa-miR-640	CLIP-seq
MIRT1078591	hsa-miR-764	CLIP-seq
MIRT2251466	hsa-miR-93	CLIP-seq
MIRT1078580	hsa-miR-1182	CLIP-seq
MIRT1078587	hsa-miR-4659a-3p	CLIP-seq
MIRT1078588	hsa-miR-4659b-3p	CLIP-seq
MIRT2452120	hsa-miR-1266	CLIP-seq
MIRT2452121	hsa-miR-1972	CLIP-seq
MIRT2452122	hsa-miR-216a	CLIP-seq
MIRT2452123	hsa-miR-298	CLIP-seq
MIRT2452124	hsa-miR-3664-3p	CLIP-seq
MIRT2452125	hsa-miR-4518	CLIP-seq
MIRT2452126	hsa-miR-4650-5p	CLIP-seq
MIRT2452127	hsa-miR-4758-3p	CLIP-seq
MIRT2251441	hsa-miR-106a	CLIP-seq
MIRT2251442	hsa-miR-106b	CLIP-seq
MIRT2251443	hsa-miR-1234	CLIP-seq
MIRT1078581	hsa-miR-125a-3p	CLIP-seq
MIRT2251444	hsa-miR-150	CLIP-seq
MIRT2251445	hsa-miR-17	CLIP-seq
MIRT2251447	hsa-miR-20a	CLIP-seq
MIRT2251448	hsa-miR-20b	CLIP-seq
MIRT2251449	hsa-miR-302a	CLIP-seq
MIRT2251450	hsa-miR-302b	CLIP-seq
MIRT2251451	hsa-miR-302c	CLIP-seq
MIRT2251452	hsa-miR-302d	CLIP-seq
MIRT2251453	hsa-miR-302e	CLIP-seq
MIRT2554667	hsa-miR-3149	CLIP-seq
MIRT2251454	hsa-miR-3194-3p	CLIP-seq
MIRT2251455	hsa-miR-372	CLIP-seq
MIRT2251456	hsa-miR-373	CLIP-seq
MIRT1078586	hsa-miR-3934	CLIP-seq
MIRT2554668	hsa-miR-4438	CLIP-seq
MIRT2554669	hsa-miR-4731-5p	CLIP-seq
MIRT2554670	hsa-miR-4735-5p	CLIP-seq
MIRT2554671	hsa-miR-4775	CLIP-seq
MIRT2251457	hsa-miR-4786-3p	CLIP-seq
MIRT2554672	hsa-miR-5095	CLIP-seq
MIRT2554673	hsa-miR-512-3p	CLIP-seq
MIRT2251458	hsa-miR-519d	CLIP-seq
MIRT2251459	hsa-miR-520a-3p	CLIP-seq
MIRT2251460	hsa-miR-520b	CLIP-seq
MIRT2251461	hsa-miR-520c-3p	CLIP-seq
MIRT2251462	hsa-miR-520d-3p	CLIP-seq
MIRT2251463	hsa-miR-520e	CLIP-seq
MIRT2251464	hsa-miR-520g	CLIP-seq
MIRT2251465	hsa-miR-520h	CLIP-seq
MIRT2554674	hsa-miR-590-3p	CLIP-seq
MIRT1078590	hsa-miR-640	CLIP-seq
MIRT1078591	hsa-miR-764	CLIP-seq
MIRT2251466	hsa-miR-93	CLIP-seq
MIRT2251441	hsa-miR-106a	CLIP-seq
MIRT2251442	hsa-miR-106b	CLIP-seq
MIRT2251443	hsa-miR-1234	CLIP-seq
MIRT1078581	hsa-miR-125a-3p	CLIP-seq
MIRT2019556	hsa-miR-1281	CLIP-seq
MIRT2019557	hsa-miR-1297	CLIP-seq
MIRT2683148	hsa-miR-136	CLIP-seq
MIRT2683149	hsa-miR-140-3p	CLIP-seq
MIRT2251444	hsa-miR-150	CLIP-seq
MIRT2251445	hsa-miR-17	CLIP-seq
MIRT2251446	hsa-miR-197	CLIP-seq
MIRT2019564	hsa-miR-1976	CLIP-seq
MIRT2251447	hsa-miR-20a	CLIP-seq
MIRT2251448	hsa-miR-20b	CLIP-seq
MIRT2019565	hsa-miR-26a	CLIP-seq
MIRT2019566	hsa-miR-26b	CLIP-seq
MIRT2683150	hsa-miR-297	CLIP-seq
MIRT2251449	hsa-miR-302a	CLIP-seq
MIRT2251450	hsa-miR-302b	CLIP-seq
MIRT2251451	hsa-miR-302c	CLIP-seq
MIRT2251452	hsa-miR-302d	CLIP-seq
MIRT2251453	hsa-miR-302e	CLIP-seq
MIRT2554667	hsa-miR-3149	CLIP-seq
MIRT2683151	hsa-miR-3155	CLIP-seq
MIRT2683152	hsa-miR-3155b	CLIP-seq
MIRT2019572	hsa-miR-3174	CLIP-seq
MIRT2251454	hsa-miR-3194-3p	CLIP-seq
MIRT2683153	hsa-miR-3200-3p	CLIP-seq
MIRT2683154	hsa-miR-3200-5p	CLIP-seq
MIRT2683155	hsa-miR-3529	CLIP-seq
MIRT2683156	hsa-miR-3662	CLIP-seq
MIRT1078582	hsa-miR-3663-5p	CLIP-seq
MIRT1078584	hsa-miR-371-5p	CLIP-seq
MIRT1078585	hsa-miR-371b-5p	CLIP-seq
MIRT2251455	hsa-miR-372	CLIP-seq
MIRT2251456	hsa-miR-373	CLIP-seq
MIRT2683157	hsa-miR-379	CLIP-seq
MIRT1078586	hsa-miR-3934	CLIP-seq
MIRT2683158	hsa-miR-4303	CLIP-seq
MIRT2554668	hsa-miR-4438	CLIP-seq
MIRT2683159	hsa-miR-4451	CLIP-seq
MIRT2019580	hsa-miR-4465	CLIP-seq
MIRT2019582	hsa-miR-4532	CLIP-seq
MIRT2683160	hsa-miR-4642	CLIP-seq
MIRT2683161	hsa-miR-4650-3p	CLIP-seq
MIRT2683162	hsa-miR-4688	CLIP-seq
MIRT2683163	hsa-miR-4698	CLIP-seq
MIRT2683164	hsa-miR-4703-3p	CLIP-seq
MIRT2683165	hsa-miR-4715-3p	CLIP-seq
MIRT2683166	hsa-miR-4716-5p	CLIP-seq
MIRT2019586	hsa-miR-4722-3p	CLIP-seq
MIRT2554669	hsa-miR-4731-5p	CLIP-seq
MIRT2554670	hsa-miR-4735-5p	CLIP-seq
MIRT2683167	hsa-miR-4763-5p	CLIP-seq
MIRT2554671	hsa-miR-4775	CLIP-seq
MIRT2251457	hsa-miR-4786-3p	CLIP-seq
MIRT2683168	hsa-miR-483-5p	CLIP-seq
MIRT2683169	hsa-miR-484	CLIP-seq
MIRT2554672	hsa-miR-5095	CLIP-seq
MIRT2554673	hsa-miR-512-3p	CLIP-seq
MIRT2683170	hsa-miR-515-5p	CLIP-seq
MIRT2251458	hsa-miR-519d	CLIP-seq
MIRT2251459	hsa-miR-520a-3p	CLIP-seq
MIRT2251460	hsa-miR-520b	CLIP-seq
MIRT2251461	hsa-miR-520c-3p	CLIP-seq
MIRT2251462	hsa-miR-520d-3p	CLIP-seq
MIRT2251463	hsa-miR-520e	CLIP-seq
MIRT2251464	hsa-miR-520g	CLIP-seq
MIRT2251465	hsa-miR-520h	CLIP-seq
MIRT2683171	hsa-miR-545	CLIP-seq
MIRT2683172	hsa-miR-562	CLIP-seq
MIRT2683173	hsa-miR-566	CLIP-seq
MIRT2683174	hsa-miR-567	CLIP-seq
MIRT2554674	hsa-miR-590-3p	CLIP-seq
MIRT2019588	hsa-miR-627	CLIP-seq
MIRT1078590	hsa-miR-640	CLIP-seq
MIRT1078591	hsa-miR-764	CLIP-seq
MIRT2019589	hsa-miR-924	CLIP-seq
MIRT2251466	hsa-miR-93	CLIP-seq

Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	25961457
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IBA
GO:0015630	Component	Microtubule cytoskeleton	IDA
GO:0030837	Process	Negative regulation of actin filament polymerization	IBA
GO:0030837	Process	Negative regulation of actin filament polymerization	IEA

MIM	HGNC	e!Ensembl
614612	27263	ENSG00000132854

Q5T7N3

Protein name

KN motif and ankyrin repeat domain-containing protein 4 (Ankyrin repeat domain-containing protein 38)

Protein function

May be involved in the control of cytoskeleton formation by regulating actin polymerization.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12075	KN_motif	24 → 62	KN motif	Motif
PF00023	Ank	823 → 856	Ankyrin repeat	Repeat
PF13857	Ank_5	915 → 970		Repeat

Tissue specificity

TISSUE SPECIFICITY: Strongly expressed in colon, liver, lung, skeletal muscle and kidney. {ECO:0000269|PubMed:17996375}.

Sequence

MEKTDAKDQSSQGDEEKDPPKSHPYSVETPYGFHLDLDFLKYVDDIEKGNTIKRIPIHRR
AKQAKFSTLPRNFSLPDSGARPPAAPPLQNWSPVVPREASLGTQEQNQSPPLGNAPQAST
SRSEVSYHRKALLAEATRQLEAAEPEDAELTFGSGRPQLLRASSMPATLLHSRASEEPGL
SLGPPAPPALPPLQGEGSVCDGTFEPAEGLAGFHSSSPRASTRIPELVQEGAEPPEGVVK
VPNHLPLPGPPFSFQNVLVVLEDKEDEHNAREAEVLFTPGSPTPSPPPLPSPIPENELLL
EEIELNISEIPPPPPVEVDMRSIGIRVTEESLGLARVDPGSISSLKQQVSALEGELSGRT
EELAQVRTALQQQEEEIKAREQRIRELEFTVAQLEGQFHQENAKDTQGQTDVMVNTDPVH
GLLTRESCDKGIEVNLLGSMESESWGHRGEENGLLWGPDGHKQGNQSPAERVLLPQLSLP
QGPEQVLTSSVHSFLSTELRIEEAGTEQEGGPQGGTRGAGGFLWGSDRKTPPAGREETSS
NLPGKEHPGRPPSSPTDATIGQYVKKIQELLQEQWNCLEHGYPELASAIKQPASKLSSIQ
SQLLSSLNLLLSAYSAQAHPPKEPPASSSSPPVEISPSTSLKSIMKKKDYGFRAGGNGTK
KNLQFVGVNGGYETTSSEETSGEDSTPEDLSDSEAEKKCDGPDHKHVKDAHLTCEAGQGI
PEGTCHAAQESGPGEEVPHSKAERYKPSEEFLNACRALSQHLPETGTTTDQLLRQSLNTI
SQEWFRVSSRKSSSPAVVASYLHEVQPHSPHFLKLLVNLADHNGNTALHYSVSHSNFSIV
KLLLETGVCNVDHQNKAGYTAVMITPLASAETNEDMAVVWKLLREGNVNIQATQGGQTAL
MLGVSHDREDMVQALLSCQADVNLQDHDGSSALMVACHHGNVDLVRLLLAHPACDSSLTD
KAGRTALSIALKSPTHMEIAGLLRAHAEQGRSLGL

Sequence length

995

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (22)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORNEAL DYSTROPHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EYE DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FUCHS ENDOTHELIAL CORNEAL DYSTROPHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FUCHS' ENDOTHELIAL DYSTROPHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KANK4-related disorder	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nephrotic syndrome	Likely benign	ClinVar Disgenet	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
NON-ALCOHOLIC FATTY LIVER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Papillary renal cell carcinoma type 1	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PERITONITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (11)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	24397353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	BEFREE	31400178		★★★★★ ★☆☆☆☆ Found in Text Mining only
Borderline Personality Disorder	Borderline personality disorder	BEFREE	31400178		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bronchopulmonary Dysplasia	Bronchopulmonary Dysplasia	BEFREE	31400178		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fuchs Endothelial Dystrophy	Fuchs Endothelial Dystrophy	GWASCAT_DG	28358029		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fuchs' Endothelial Dystrophy	Fuchs endothelial dystrophy	Pubtator	28358029	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	38211648	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nephrotic Syndrome	Nephrotic Syndrome	BEFREE	25961457		★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Osteoarthritis	Osteoarthritis	Pubtator	24397353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	37036756	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	24397353		★★★★★ ★☆☆☆☆ Found in Text Mining only

KANK4 (KN motif and ankyrin repeat domains 4)