Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	162461
Gene name	Transmembrane protein 92
Gene symbol	TMEM92
Synonyms (NCBI Gene)	-
Chromosome	17
Chromosome location	17q21.33

Show/Hide all (1)

SNP ID	Visualize variation	Clinical significance	Consequence
rs730882247	A>G	Likely-pathogenic	Intron variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT652361	hsa-miR-5196-3p	HITS-CLIP	23824327
MIRT652360	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT652359	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT652358	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT652357	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT652356	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT652355	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT652354	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT652361	hsa-miR-5196-3p	HITS-CLIP	23824327
MIRT652360	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT652359	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT652358	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT652357	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT652356	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT652355	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT652354	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT1439605	hsa-miR-1207-5p	CLIP-seq
MIRT1439606	hsa-miR-1343	CLIP-seq
MIRT1439607	hsa-miR-2392	CLIP-seq
MIRT1439608	hsa-miR-4763-3p	CLIP-seq
MIRT1439609	hsa-miR-1200	CLIP-seq
MIRT1439610	hsa-miR-3187-3p	CLIP-seq
MIRT1439611	hsa-miR-3616-3p	CLIP-seq
MIRT1439612	hsa-miR-4324	CLIP-seq
MIRT1439613	hsa-miR-4435	CLIP-seq
MIRT1439614	hsa-miR-4436b-5p	CLIP-seq
MIRT1439615	hsa-miR-4701-5p	CLIP-seq
MIRT1439616	hsa-miR-4710	CLIP-seq
MIRT1439617	hsa-miR-4721	CLIP-seq
MIRT1439618	hsa-miR-4735-5p	CLIP-seq
MIRT1439619	hsa-miR-4755-3p	CLIP-seq
MIRT1439620	hsa-miR-4766-5p	CLIP-seq
MIRT1439621	hsa-miR-544	CLIP-seq
MIRT1439622	hsa-miR-544b	CLIP-seq
MIRT1439623	hsa-miR-548a-5p	CLIP-seq
MIRT1439624	hsa-miR-548ab	CLIP-seq
MIRT1439625	hsa-miR-548ak	CLIP-seq
MIRT1439626	hsa-miR-548b-5p	CLIP-seq
MIRT1439627	hsa-miR-548c-5p	CLIP-seq
MIRT1439628	hsa-miR-548d-5p	CLIP-seq
MIRT1439629	hsa-miR-548h	CLIP-seq
MIRT1439630	hsa-miR-548i	CLIP-seq
MIRT1439631	hsa-miR-548j	CLIP-seq
MIRT1439632	hsa-miR-548s	CLIP-seq
MIRT1439633	hsa-miR-548w	CLIP-seq
MIRT1439634	hsa-miR-548y	CLIP-seq
MIRT1439635	hsa-miR-559	CLIP-seq
MIRT1439636	hsa-miR-588	CLIP-seq
MIRT2131634	hsa-miR-1827	CLIP-seq
MIRT2352961	hsa-miR-3150a-3p	CLIP-seq
MIRT2352962	hsa-miR-3175	CLIP-seq
MIRT2352963	hsa-miR-3617	CLIP-seq
MIRT2352964	hsa-miR-4667-5p	CLIP-seq
MIRT2352965	hsa-miR-4695-5p	CLIP-seq
MIRT2352966	hsa-miR-4700-5p	CLIP-seq
MIRT2352967	hsa-miR-628-5p	CLIP-seq
MIRT2352968	hsa-miR-641	CLIP-seq
MIRT2352969	hsa-miR-765	CLIP-seq
MIRT2352970	hsa-miR-939	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005654	Component	Nucleoplasm	IBA
GO:0005654	Component	Nucleoplasm	IDA
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
619604	26579	ENSG00000167105

Q6UXU6

Protein name

Transmembrane protein 92

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF11669	WBP-1	32 → 141	WW domain-binding protein 1	Family

Sequence

MSQAWVPGLAPTLLFSLLAGPQKIAAKCGLILACPKGFKCCGDSCCQENELFPGPVRIFV
IIFLVILSVFCICGLAKCFCRNCREPEPDSPVDCRGPLELPSIIPPERVRVSLSAPPPPY
SEVILKPSLGPTPTEPPPPYSFRPEEYTGDQRGIDNPAF

Sequence length

159

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Bilateral squint	Likely pathogenic	rs730882247	RCV000162187	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Cerebellar atrophy	Likely pathogenic	rs730882247	RCV000162187	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Global developmental delay	Likely pathogenic	rs730882247	RCV000162187	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Hydrocephalus	Likely pathogenic	rs730882247	RCV000162187	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
NERVOUS SYSTEM DISORDER	—	Disgenet, GenCC Disgenet, GenCC	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Cerebellar atrophy	Cerebellar atrophy	CLINVAR_DG	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Global developmental delay	Developmental Delay	CLINVAR_DG	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Hydrocephalus	Hydrocephalus	CLINVAR_DG	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

TMEM92 (transmembrane protein 92)