Gene Gene information from NCBI Gene database.
Entrez ID 162239
Gene name ZFP1 zinc finger protein
Gene symbol ZFP1
Synonyms (NCBI Gene)
ZNF475
Chromosome 16
Chromosome location 16q23.1
Summary This gene belongs to the zinc finger protein family. Some members of this family bind to DNA by zinc-mediated secondary structures called zinc fingers, and are involved in transcriptional regulation. Alternative splicing results in multiple transcript var
miRNA miRNA information provided by mirtarbase database.
468
miRTarBase ID miRNA Experiments Reference
MIRT024656 hsa-miR-215-5p Microarray 19074876
MIRT026328 hsa-miR-192-5p Microarray 19074876
MIRT643173 hsa-miR-8485 HITS-CLIP 23824327
MIRT643172 hsa-miR-329-3p HITS-CLIP 23824327
MIRT643171 hsa-miR-362-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
617230 23328 ENSG00000184517
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6P2D0
Protein name Zinc finger protein 1 homolog (Zfp-1) (Zinc finger protein 475)
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 7 48 KRAB box Family
PF00096 zf-C2H2 184 206 Zinc finger, C2H2 type Domain
PF13465 zf-H2C2_2 226 251 Domain
PF00096 zf-C2H2 268 290 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 296 318 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 324 346 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 352 374 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 380 402 Zinc finger, C2H2 type Domain
Sequence
MNKSQGSVSFTDVTVDFTQEEWEQLDPSQRILYMDVMLENYSNLLSVEVWKADDQMERDH
RNPDEQARQFLILKNQTPIEERGDLFGKALNLNTDFVSLRQVPYKYDLYEKTLKYNSDLL
NSNRSYAGKQTDECNEFGKALLYLKQEKTHSGVEYSEYNKSGKALSHKAAIFKHQKIKNL
VQPFICTYCDKAFSFKSLLISHKRIHTGEKPYECNVCKKTFSHKANLIKHQRIHTGEKPF
ECPECGKAFTH
QSNLIVHQRAHMEKKPYECSECGKTFAQKFELTTHQRIHTGERPYECNE
CAKTFFKKSNLIIHQKIH
TGEKRYECSECGKSFIQNSQLIIHMRTHTGEKPYECTECGKT
FSQRSTLRLHLRIH
TGEKPYECSECGKAFSRKSRLSVHQRVHIGEKP
Sequence length 407
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
9
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATROPHIC MACULAR DEGENERATION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CROHN'S DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
DIABETES MELLITUS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Stomach Neoplasms Stomach neoplasms Pubtator 39261568 Associate
★☆☆☆☆
Found in Text Mining only