TDRP (testis development related protein)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 157695
Gene name Testis development related protein
Gene symbol TDRP
Synonyms (NCBI Gene)
C8orf42Inm01TDRP1TDRP2
Chromosome 8
Chromosome location 8p23.3
miRNA miRNA information provided by mirtarbase database.
6
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (6)
miRTarBase ID miRNA Experiments Reference
MIRT024144 hsa-miR-221-3p Sequencing 20371350
MIRT030409 hsa-miR-24-3p Microarray 19748357
MIRT495831 hsa-miR-1295b-3p PAR-CLIP 22291592
MIRT495830 hsa-miR-3671 PAR-CLIP 22291592
MIRT495831 hsa-miR-1295b-3p PAR-CLIP 22291592
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (11)
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IDA 20170638
GO:0005634 Component Nucleus IEA
GO:0005737 Component Cytoplasm IDA 20170638
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
619049 26951 ENSG00000180190
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q86YL5
Protein name Testis development-related protein (Protein INM01)
Protein function Contributes to normal sperm motility, but not essential for male fertility.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15683 TDRP 39 → 185 Testis development-related protein Family
Tissue specificity TISSUE SPECIFICITY: Expressed in spermatogenic cells, especially in spermatocytes (at protein level). {ECO:0000269|PubMed:20170638}.
Sequence
Sequence length 185
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (2)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATROPHIC MACULAR DEGENERATION — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (2)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Geographic Atrophy Geographic Atrophy BEFREE 24667176
★★★★★
★☆☆☆☆
Found in Text Mining only
Macular Degeneration Macular degeneration Pubtator 24667176 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only