FMC1 (formation of mitochondrial complex V assembly factor 1)

Gene

• Entrez ID: 154791
• Gene name: Formation of mitochondrial complex V assembly factor 1
• Gene symbol: FMC1
• Synonyms (NCBI Gene): C7orf55, HSPC268
• Chromosome: 7
• Chromosome location: 7q34

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT518233	hsa-miR-4438	PAR-CLIP	23446348
MIRT518232	hsa-miR-4794	PAR-CLIP	23446348
MIRT518231	hsa-miR-664a-5p	PAR-CLIP	23446348
MIRT518230	hsa-miR-1254	PAR-CLIP	23446348
MIRT518229	hsa-miR-3116	PAR-CLIP	23446348
MIRT518228	hsa-miR-661	PAR-CLIP	23446348
MIRT518227	hsa-miR-1271-3p	PAR-CLIP	23446348
MIRT518226	hsa-miR-550a-3-5p	PAR-CLIP	23446348
MIRT518225	hsa-miR-550a-5p	PAR-CLIP	23446348
MIRT518224	hsa-miR-5095	PAR-CLIP	23446348
MIRT518223	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT518222	hsa-miR-6807-5p	PAR-CLIP	23446348

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28719601
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	28719601
GO:0005739	Component	Mitochondrion	IEA
GO:0007005	Process	Mitochondrion organization	IEA
GO:0008637	Process	Apoptotic mitochondrial changes	IEA
GO:0009636	Process	Response to toxic substance	IEA
GO:0033615	Process	Mitochondrial proton-transporting ATP synthase complex assembly	IMP	28719601
GO:0050995	Process	Negative regulation of lipid catabolic process	IEA
GO:0061469	Process	Regulation of type B pancreatic cell proliferation	IEA
GO:0061744	Process	Motor behavior	IEA
GO:0071542	Process	Dopaminergic neuron differentiation	IEA

Other IDs

• MIM: 620766
• HGNC: 26946
• e!Ensembl: ENSG00000164898

Interactions View interactions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
PARKINSON DISEASE, MITOCHONDRIAL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE, SECONDARY	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SECONDARY PARKINSON DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
USHER SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations