Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Other IDs Protein Associated diseases
Entrez ID	154661
Gene name	RUN domain containing 3B
Gene symbol	RUNDC3B
Synonyms (NCBI Gene)	RPIB9RPIP9
Chromosome	7
Chromosome location	7q21.12

Show/Hide all (98)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018076	hsa-miR-335-5p	Microarray	18185580
MIRT051186	hsa-miR-16-5p	CLASH	23622248
MIRT049850	hsa-miR-33a-5p	CLASH	23622248
MIRT048679	hsa-miR-99a-5p	CLASH	23622248
MIRT048370	hsa-miR-29b-3p	CLASH	23622248
MIRT047582	hsa-miR-10a-5p	CLASH	23622248
MIRT047438	hsa-miR-10b-5p	CLASH	23622248
MIRT046837	hsa-miR-221-3p	CLASH	23622248
MIRT038753	hsa-miR-93-3p	CLASH	23622248
MIRT714072	hsa-miR-4660	HITS-CLIP	19536157
MIRT714071	hsa-miR-4252	HITS-CLIP	19536157
MIRT714070	hsa-miR-1301-3p	HITS-CLIP	19536157
MIRT714069	hsa-miR-5047	HITS-CLIP	19536157
MIRT714072	hsa-miR-4660	HITS-CLIP	19536157
MIRT714071	hsa-miR-4252	HITS-CLIP	19536157
MIRT714070	hsa-miR-1301-3p	HITS-CLIP	19536157
MIRT714069	hsa-miR-5047	HITS-CLIP	19536157
MIRT572908	hsa-miR-561-3p	PAR-CLIP	20371350
MIRT572907	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT572906	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT572905	hsa-miR-5088-3p	PAR-CLIP	20371350
MIRT572904	hsa-miR-150-5p	PAR-CLIP	20371350
MIRT572903	hsa-miR-532-3p	PAR-CLIP	20371350
MIRT572902	hsa-miR-2116-3p	PAR-CLIP	20371350
MIRT572900	hsa-miR-4287	PAR-CLIP	20371350
MIRT572901	hsa-miR-4685-3p	PAR-CLIP	20371350
MIRT572899	hsa-miR-4713-5p	PAR-CLIP	20371350
MIRT572898	hsa-miR-6867-3p	PAR-CLIP	20371350
MIRT572897	hsa-miR-587	PAR-CLIP	20371350
MIRT572896	hsa-miR-629-3p	PAR-CLIP	20371350
MIRT572895	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT714072	hsa-miR-4660	HITS-CLIP	19536157
MIRT714071	hsa-miR-4252	HITS-CLIP	19536157
MIRT714070	hsa-miR-1301-3p	HITS-CLIP	19536157
MIRT714069	hsa-miR-5047	HITS-CLIP	19536157
MIRT714072	hsa-miR-4660	HITS-CLIP	19536157
MIRT714071	hsa-miR-4252	HITS-CLIP	19536157
MIRT714070	hsa-miR-1301-3p	HITS-CLIP	19536157
MIRT714069	hsa-miR-5047	HITS-CLIP	19536157
MIRT572908	hsa-miR-561-3p	PAR-CLIP	20371350
MIRT572907	hsa-miR-483-3p	PAR-CLIP	20371350
MIRT572906	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT572905	hsa-miR-5088-3p	PAR-CLIP	20371350
MIRT572904	hsa-miR-150-5p	PAR-CLIP	20371350
MIRT572903	hsa-miR-532-3p	PAR-CLIP	20371350
MIRT572902	hsa-miR-2116-3p	PAR-CLIP	20371350
MIRT572900	hsa-miR-4287	PAR-CLIP	20371350
MIRT572901	hsa-miR-4685-3p	PAR-CLIP	20371350
MIRT572899	hsa-miR-4713-5p	PAR-CLIP	20371350
MIRT572898	hsa-miR-6867-3p	PAR-CLIP	20371350
MIRT572897	hsa-miR-587	PAR-CLIP	20371350
MIRT572896	hsa-miR-629-3p	PAR-CLIP	20371350
MIRT572895	hsa-miR-3124-3p	PAR-CLIP	20371350
MIRT1322716	hsa-miR-3156-5p	CLIP-seq
MIRT1322717	hsa-miR-3173-3p	CLIP-seq
MIRT1322718	hsa-miR-3647-3p	CLIP-seq
MIRT1322719	hsa-miR-515-5p	CLIP-seq
MIRT1322720	hsa-miR-1264	CLIP-seq
MIRT1322721	hsa-miR-21	CLIP-seq
MIRT1322722	hsa-miR-326	CLIP-seq
MIRT1322723	hsa-miR-330-5p	CLIP-seq
MIRT1322718	hsa-miR-3647-3p	CLIP-seq
MIRT1322724	hsa-miR-4427	CLIP-seq
MIRT1322725	hsa-miR-4720-3p	CLIP-seq
MIRT1322726	hsa-miR-516b	CLIP-seq
MIRT1322727	hsa-miR-548a-3p	CLIP-seq
MIRT1322728	hsa-miR-548e	CLIP-seq
MIRT1322729	hsa-miR-548f	CLIP-seq
MIRT1322730	hsa-miR-590-5p	CLIP-seq
MIRT1322731	hsa-miR-593	CLIP-seq
MIRT1322718	hsa-miR-3647-3p	CLIP-seq
MIRT1322724	hsa-miR-4427	CLIP-seq
MIRT1322732	hsa-miR-522	CLIP-seq
MIRT1322727	hsa-miR-548a-3p	CLIP-seq
MIRT1322728	hsa-miR-548e	CLIP-seq
MIRT1322729	hsa-miR-548f	CLIP-seq
MIRT1322718	hsa-miR-3647-3p	CLIP-seq
MIRT1322724	hsa-miR-4427	CLIP-seq
MIRT2095742	hsa-miR-3163	CLIP-seq
MIRT2095743	hsa-miR-4495	CLIP-seq
MIRT2095744	hsa-miR-4795-3p	CLIP-seq
MIRT2095745	hsa-miR-3137	CLIP-seq
MIRT2095742	hsa-miR-3163	CLIP-seq
MIRT2095746	hsa-miR-3664-5p	CLIP-seq
MIRT2095747	hsa-miR-4680-5p	CLIP-seq
MIRT2320186	hsa-miR-1271	CLIP-seq
MIRT2320187	hsa-miR-182	CLIP-seq
MIRT2320188	hsa-miR-186	CLIP-seq
MIRT1322718	hsa-miR-3647-3p	CLIP-seq
MIRT2320189	hsa-miR-4307	CLIP-seq
MIRT1322724	hsa-miR-4427	CLIP-seq
MIRT2320190	hsa-miR-9	CLIP-seq
MIRT2320191	hsa-miR-96	CLIP-seq
MIRT1322718	hsa-miR-3647-3p	CLIP-seq
MIRT2393956	hsa-miR-371-5p	CLIP-seq
MIRT2393957	hsa-miR-371b-5p	CLIP-seq
MIRT1322724	hsa-miR-4427	CLIP-seq
MIRT2393958	hsa-miR-4762-5p	CLIP-seq

MIM	HGNC	e!Ensembl
617295	30286	ENSG00000105784

Q96NL0

Protein name

RUN domain-containing protein 3B (Rap2-binding protein 9) (Rap2-interacting protein 9) (RPIP-9)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02759	RUN	65 → 205	RUN domain	Family

Tissue specificity

TISSUE SPECIFICITY: Isoform 2 is expressed at high levels in brain, thymus, ovary, testis, leukocyte, liver, small intestine and prostate. Isoform 1 is expressed in the brain, testis and adrenal gland. It is activated in tumorigenic breast cancer cell lin

Sequence

MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS
PEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRK
VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL
GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT
LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES
VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS
PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL
NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS

Sequence length

473

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (8)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Carcinoma	Breast Carcinoma	BEFREE	15986426		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	26011749	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	26011749	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	26011749		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	26011749	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	26011749		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	15986426, 17363581		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	34326198	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

RUNDC3B (RUN domain containing 3B)