CREBRF (CREB3 regulatory factor)

Gene

• Entrez ID: 153222
• Gene name: CREB3 regulatory factor
• Gene symbol: CREBRF
• Synonyms (NCBI Gene): C5orf41, LRF
• Chromosome: 5
• Chromosome location: 5q35.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005103	hsa-miR-155-5p	Microarray	19193853
MIRT016126	hsa-miR-421	Sequencing	20371350
MIRT017940	hsa-miR-335-5p	Microarray	18185580
MIRT028082	hsa-miR-93-5p	Sequencing	20371350
MIRT045087	hsa-miR-186-5p	CLASH	23622248
MIRT042350	hsa-miR-484	CLASH	23622248
MIRT165943	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT567963	hsa-miR-3074-3p	HITS-CLIP	21572407
MIRT507662	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT524342	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT312939	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT215380	hsa-miR-147a	HITS-CLIP	21572407
MIRT478867	hsa-miR-6083	HITS-CLIP	21572407
MIRT524340	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT708148	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT215298	hsa-miR-369-3p	HITS-CLIP	21572407
MIRT238466	hsa-miR-374c-5p	HITS-CLIP	21572407
MIRT238463	hsa-miR-655-3p	HITS-CLIP	21572407
MIRT538396	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT165943	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT567963	hsa-miR-3074-3p	HITS-CLIP	21572407
MIRT524343	hsa-miR-136-3p	HITS-CLIP	21572407
MIRT507662	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT524342	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT312939	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT478867	hsa-miR-6083	HITS-CLIP	21572407
MIRT538396	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT524340	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT507661	hsa-miR-577	HITS-CLIP	23313552
MIRT704465	hsa-miR-1246	HITS-CLIP	23313552
MIRT507660	hsa-miR-1237-3p	HITS-CLIP	23313552
MIRT507659	hsa-miR-1248	HITS-CLIP	23313552
MIRT507658	hsa-miR-3137	HITS-CLIP	23313552
MIRT507657	hsa-miR-20b-3p	HITS-CLIP	23313552
MIRT507656	hsa-miR-3182	HITS-CLIP	23313552
MIRT507655	hsa-miR-4268	HITS-CLIP	23313552
MIRT507654	hsa-miR-4448	HITS-CLIP	23313552
MIRT391434	hsa-miR-711	HITS-CLIP	23313552
MIRT507653	hsa-miR-3935	HITS-CLIP	23313552
MIRT507652	hsa-miR-376a-2-5p	HITS-CLIP	23313552
MIRT507651	hsa-miR-6868-3p	HITS-CLIP	23313552
MIRT507650	hsa-miR-3686	HITS-CLIP	23313552
MIRT507649	hsa-miR-6772-3p	HITS-CLIP	23313552
MIRT507648	hsa-miR-4776-5p	HITS-CLIP	23313552
MIRT507647	hsa-miR-4535	HITS-CLIP	23313552
MIRT165943	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT524343	hsa-miR-136-3p	HITS-CLIP	23313552
MIRT312939	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT524341	hsa-miR-526b-5p	HITS-CLIP	23313552
MIRT478867	hsa-miR-6083	HITS-CLIP	23313552
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT567963	hsa-miR-3074-3p	PAR-CLIP	20371350
MIRT524343	hsa-miR-136-3p	PAR-CLIP	20371350
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT478867	hsa-miR-6083	PAR-CLIP	20371350
MIRT215347	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT215342	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT312929	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT408338	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT408340	hsa-miR-506-3p	PAR-CLIP	20371350
MIRT408338	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT567961	hsa-miR-3714	PAR-CLIP	20371350
MIRT567962	hsa-miR-3910	PAR-CLIP	20371350
MIRT478884	hsa-miR-6882-5p	PAR-CLIP	20371350
MIRT408339	hsa-miR-338-5p	PAR-CLIP	20371350
MIRT567960	hsa-miR-449b-3p	PAR-CLIP	20371350
MIRT408341	hsa-miR-5582-5p	PAR-CLIP	20371350
MIRT312925	hsa-let-7c-3p	PAR-CLIP	20371350
MIRT548735	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT548734	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT215387	hsa-miR-8066	PAR-CLIP	21572407
MIRT548733	hsa-miR-4778-3p	PAR-CLIP	21572407
MIRT548732	hsa-miR-6740-3p	PAR-CLIP	21572407
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT507662	hsa-miR-223-5p	PAR-CLIP	22012620
MIRT524342	hsa-miR-6867-5p	PAR-CLIP	22012620
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT478867	hsa-miR-6083	PAR-CLIP	22012620
MIRT538396	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT524340	hsa-miR-574-5p	PAR-CLIP	22012620
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT524343	hsa-miR-136-3p	PAR-CLIP	23446348
MIRT507662	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT524342	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT524341	hsa-miR-526b-5p	PAR-CLIP	23446348
MIRT478867	hsa-miR-6083	PAR-CLIP	23446348
MIRT524340	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT507662	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT478867	hsa-miR-6083	PAR-CLIP	23446348
MIRT507661	hsa-miR-577	PAR-CLIP	23446348
MIRT507660	hsa-miR-1237-3p	PAR-CLIP	23446348
MIRT507659	hsa-miR-1248	PAR-CLIP	23446348
MIRT507658	hsa-miR-3137	PAR-CLIP	23446348
MIRT507657	hsa-miR-20b-3p	PAR-CLIP	23446348
MIRT507656	hsa-miR-3182	PAR-CLIP	23446348
MIRT507655	hsa-miR-4268	PAR-CLIP	23446348
MIRT507654	hsa-miR-4448	PAR-CLIP	23446348
MIRT391434	hsa-miR-711	PAR-CLIP	23446348
MIRT507653	hsa-miR-3935	PAR-CLIP	23446348
MIRT507652	hsa-miR-376a-2-5p	PAR-CLIP	23446348
MIRT507651	hsa-miR-6868-3p	PAR-CLIP	23446348
MIRT507650	hsa-miR-3686	PAR-CLIP	23446348
MIRT507649	hsa-miR-6772-3p	PAR-CLIP	23446348
MIRT507648	hsa-miR-4776-5p	PAR-CLIP	23446348
MIRT507647	hsa-miR-4535	PAR-CLIP	23446348
MIRT507646	hsa-miR-4694-3p	PAR-CLIP	23446348
MIRT507645	hsa-miR-224-3p	PAR-CLIP	23446348
MIRT507644	hsa-miR-522-3p	PAR-CLIP	23446348
MIRT371380	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT371379	hsa-miR-641	PAR-CLIP	23446348
MIRT165922	hsa-miR-519a-3p	PAR-CLIP	23446348
MIRT165915	hsa-miR-519b-3p	PAR-CLIP	23446348
MIRT165912	hsa-miR-519c-3p	PAR-CLIP	23446348
MIRT165898	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT165899	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT165900	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT165901	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT165933	hsa-miR-302e	PAR-CLIP	23446348
MIRT165902	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT165903	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT165913	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT165916	hsa-miR-520b	PAR-CLIP	23446348
MIRT165917	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT165919	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT165910	hsa-miR-520e	PAR-CLIP	23446348
MIRT507643	hsa-miR-298	PAR-CLIP	23446348
MIRT507642	hsa-miR-155-3p	PAR-CLIP	23446348
MIRT371382	hsa-miR-4799-5p	PAR-CLIP	23446348
MIRT507640	hsa-miR-4701-5p	PAR-CLIP	23446348
MIRT507641	hsa-miR-588	PAR-CLIP	23446348
MIRT507639	hsa-miR-3685	PAR-CLIP	23446348
MIRT478884	hsa-miR-6882-5p	PAR-CLIP	23592263
MIRT478883	hsa-miR-4773	PAR-CLIP	23592263
MIRT478882	hsa-miR-300	PAR-CLIP	23592263
MIRT478881	hsa-miR-381-3p	PAR-CLIP	23592263
MIRT478880	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT215288	hsa-miR-758-5p	PAR-CLIP	23592263
MIRT478879	hsa-miR-5186	PAR-CLIP	23592263
MIRT215289	hsa-miR-3148	PAR-CLIP	23592263
MIRT215290	hsa-miR-6124	PAR-CLIP	23592263
MIRT478878	hsa-miR-323b-5p	PAR-CLIP	23592263
MIRT478877	hsa-miR-410-5p	PAR-CLIP	23592263
MIRT478876	hsa-miR-494-5p	PAR-CLIP	23592263
MIRT238468	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT478875	hsa-miR-5687	PAR-CLIP	23592263
MIRT165879	hsa-let-7a-3p	PAR-CLIP	23592263
MIRT165880	hsa-let-7b-3p	PAR-CLIP	23592263
MIRT165881	hsa-let-7f-1-3p	PAR-CLIP	23592263
MIRT165887	hsa-miR-98-3p	PAR-CLIP	23592263
MIRT215291	hsa-miR-6833-5p	PAR-CLIP	23592263
MIRT478874	hsa-miR-4752	PAR-CLIP	23592263
MIRT165929	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT165893	hsa-miR-15b-5p	PAR-CLIP	23592263
MIRT165904	hsa-miR-424-5p	PAR-CLIP	23592263
MIRT165883	hsa-miR-15a-5p	PAR-CLIP	23592263
MIRT165947	hsa-miR-6838-5p	PAR-CLIP	23592263
MIRT165908	hsa-miR-497-5p	PAR-CLIP	23592263
MIRT165896	hsa-miR-195-5p	PAR-CLIP	23592263
MIRT165884	hsa-miR-16-5p	PAR-CLIP	23592263
MIRT215381	hsa-miR-503-5p	PAR-CLIP	23592263
MIRT165944	hsa-miR-5197-5p	PAR-CLIP	23592263
MIRT215383	hsa-miR-646	PAR-CLIP	23592263
MIRT165941	hsa-miR-4690-3p	PAR-CLIP	23592263
MIRT165946	hsa-miR-5685	PAR-CLIP	23592263
MIRT478868	hsa-miR-4750-3p	PAR-CLIP	23592263
MIRT478873	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT478872	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT478871	hsa-miR-4736	PAR-CLIP	23592263
MIRT165939	hsa-miR-4524a-5p	PAR-CLIP	23592263
MIRT165945	hsa-miR-4524b-5p	PAR-CLIP	23592263
MIRT165937	hsa-miR-4256	PAR-CLIP	23592263
MIRT165948	hsa-miR-7150	PAR-CLIP	23592263
MIRT165930	hsa-miR-374b-3p	PAR-CLIP	23592263
MIRT165891	hsa-miR-107	PAR-CLIP	23592263
MIRT165888	hsa-miR-103a-3p	PAR-CLIP	23592263
MIRT478870	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT478869	hsa-miR-5694	PAR-CLIP	23592263
MIRT165931	hsa-miR-1179	PAR-CLIP	23592263
MIRT215351	hsa-miR-329-5p	PAR-CLIP	23592263
MIRT215297	hsa-miR-5697	PAR-CLIP	23592263
MIRT165936	hsa-miR-4310	PAR-CLIP	23592263
MIRT165949	hsa-miR-7157-5p	PAR-CLIP	23592263
MIRT478868	hsa-miR-4750-3p	PAR-CLIP	23592263
MIRT165932	hsa-miR-1184	PAR-CLIP	23592263
MIRT312931	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	23592263
MIRT215353	hsa-miR-1297	PAR-CLIP	23592263
MIRT215349	hsa-miR-26a-5p	PAR-CLIP	23592263
MIRT215350	hsa-miR-26b-5p	PAR-CLIP	23592263
MIRT215355	hsa-miR-4465	PAR-CLIP	23592263
MIRT215352	hsa-miR-639	PAR-CLIP	23592263
MIRT165937	hsa-miR-4256	PAR-CLIP	23592263
MIRT312932	hsa-miR-5006-5p	PAR-CLIP	23592263
MIRT478867	hsa-miR-6083	PAR-CLIP	23592263
MIRT449110	hsa-miR-320a	PAR-CLIP	22100165
MIRT449109	hsa-miR-320b	PAR-CLIP	22100165
MIRT449108	hsa-miR-320c	PAR-CLIP	22100165
MIRT449107	hsa-miR-320d	PAR-CLIP	22100165
MIRT449106	hsa-miR-4429	PAR-CLIP	22100165
MIRT449105	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT017940	hsa-miR-335-5p	PAR-CLIP	22100165
MIRT449104	hsa-miR-9-3p	PAR-CLIP	22100165
MIRT165883	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT165893	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT165884	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT165896	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT507642	hsa-miR-155-3p	Luciferase reporter assay	27163161
MIRT507642	hsa-miR-155-3p	Luciferase reporter assay	27163161
MIRT507642	hsa-miR-155-3p	Luciferase reporter assay	27163161
MIRT165943	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT567963	hsa-miR-3074-3p	HITS-CLIP	21572407
MIRT507662	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT524342	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT312939	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT215380	hsa-miR-147a	HITS-CLIP	21572407
MIRT478867	hsa-miR-6083	HITS-CLIP	21572407
MIRT524340	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT708148	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT215298	hsa-miR-369-3p	HITS-CLIP	21572407
MIRT238466	hsa-miR-374c-5p	HITS-CLIP	21572407
MIRT238463	hsa-miR-655-3p	HITS-CLIP	21572407
MIRT538396	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT165943	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT567963	hsa-miR-3074-3p	HITS-CLIP	21572407
MIRT524343	hsa-miR-136-3p	HITS-CLIP	21572407
MIRT507662	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT524342	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT312939	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT478867	hsa-miR-6083	HITS-CLIP	21572407
MIRT538396	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT524340	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT507661	hsa-miR-577	HITS-CLIP	23313552
MIRT704465	hsa-miR-1246	HITS-CLIP	23313552
MIRT507660	hsa-miR-1237-3p	HITS-CLIP	23313552
MIRT507659	hsa-miR-1248	HITS-CLIP	23313552
MIRT507658	hsa-miR-3137	HITS-CLIP	23313552
MIRT507657	hsa-miR-20b-3p	HITS-CLIP	23313552
MIRT507656	hsa-miR-3182	HITS-CLIP	23313552
MIRT507655	hsa-miR-4268	HITS-CLIP	23313552
MIRT507654	hsa-miR-4448	HITS-CLIP	23313552
MIRT391434	hsa-miR-711	HITS-CLIP	23313552
MIRT507653	hsa-miR-3935	HITS-CLIP	23313552
MIRT507652	hsa-miR-376a-2-5p	HITS-CLIP	23313552
MIRT507651	hsa-miR-6868-3p	HITS-CLIP	23313552
MIRT507650	hsa-miR-3686	HITS-CLIP	23313552
MIRT507649	hsa-miR-6772-3p	HITS-CLIP	23313552
MIRT507648	hsa-miR-4776-5p	HITS-CLIP	23313552
MIRT507647	hsa-miR-4535	HITS-CLIP	23313552
MIRT165943	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT524343	hsa-miR-136-3p	HITS-CLIP	23313552
MIRT312939	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT524341	hsa-miR-526b-5p	HITS-CLIP	23313552
MIRT478867	hsa-miR-6083	HITS-CLIP	23313552
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT567963	hsa-miR-3074-3p	PAR-CLIP	20371350
MIRT524343	hsa-miR-136-3p	PAR-CLIP	20371350
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT478867	hsa-miR-6083	PAR-CLIP	20371350
MIRT215347	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT215342	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT312929	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT408338	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT408340	hsa-miR-506-3p	PAR-CLIP	20371350
MIRT408338	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT567961	hsa-miR-3714	PAR-CLIP	20371350
MIRT567962	hsa-miR-3910	PAR-CLIP	20371350
MIRT478884	hsa-miR-6882-5p	PAR-CLIP	20371350
MIRT408339	hsa-miR-338-5p	PAR-CLIP	20371350
MIRT567960	hsa-miR-449b-3p	PAR-CLIP	20371350
MIRT408341	hsa-miR-5582-5p	PAR-CLIP	20371350
MIRT312925	hsa-let-7c-3p	PAR-CLIP	20371350
MIRT548735	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT548734	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT215387	hsa-miR-8066	PAR-CLIP	21572407
MIRT548733	hsa-miR-4778-3p	PAR-CLIP	21572407
MIRT548732	hsa-miR-6740-3p	PAR-CLIP	21572407
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT507662	hsa-miR-223-5p	PAR-CLIP	22012620
MIRT524342	hsa-miR-6867-5p	PAR-CLIP	22012620
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT478867	hsa-miR-6083	PAR-CLIP	22012620
MIRT538396	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT524340	hsa-miR-574-5p	PAR-CLIP	22012620
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT524343	hsa-miR-136-3p	PAR-CLIP	23446348
MIRT507662	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT524342	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT524341	hsa-miR-526b-5p	PAR-CLIP	23446348
MIRT478867	hsa-miR-6083	PAR-CLIP	23446348
MIRT524340	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT165943	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT507662	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT478867	hsa-miR-6083	PAR-CLIP	23446348
MIRT507661	hsa-miR-577	PAR-CLIP	23446348
MIRT507660	hsa-miR-1237-3p	PAR-CLIP	23446348
MIRT507659	hsa-miR-1248	PAR-CLIP	23446348
MIRT507658	hsa-miR-3137	PAR-CLIP	23446348
MIRT507657	hsa-miR-20b-3p	PAR-CLIP	23446348
MIRT507656	hsa-miR-3182	PAR-CLIP	23446348
MIRT507655	hsa-miR-4268	PAR-CLIP	23446348
MIRT507654	hsa-miR-4448	PAR-CLIP	23446348
MIRT391434	hsa-miR-711	PAR-CLIP	23446348
MIRT507653	hsa-miR-3935	PAR-CLIP	23446348
MIRT507652	hsa-miR-376a-2-5p	PAR-CLIP	23446348
MIRT507651	hsa-miR-6868-3p	PAR-CLIP	23446348
MIRT507650	hsa-miR-3686	PAR-CLIP	23446348
MIRT507649	hsa-miR-6772-3p	PAR-CLIP	23446348
MIRT507648	hsa-miR-4776-5p	PAR-CLIP	23446348
MIRT507647	hsa-miR-4535	PAR-CLIP	23446348
MIRT507646	hsa-miR-4694-3p	PAR-CLIP	23446348
MIRT507645	hsa-miR-224-3p	PAR-CLIP	23446348
MIRT507644	hsa-miR-522-3p	PAR-CLIP	23446348
MIRT371380	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT371379	hsa-miR-641	PAR-CLIP	23446348
MIRT165922	hsa-miR-519a-3p	PAR-CLIP	23446348
MIRT165915	hsa-miR-519b-3p	PAR-CLIP	23446348
MIRT165912	hsa-miR-519c-3p	PAR-CLIP	23446348
MIRT165898	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT165899	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT165900	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT165901	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT165933	hsa-miR-302e	PAR-CLIP	23446348
MIRT165902	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT165903	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT165913	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT165916	hsa-miR-520b	PAR-CLIP	23446348
MIRT165917	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT165919	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT165910	hsa-miR-520e	PAR-CLIP	23446348
MIRT507643	hsa-miR-298	PAR-CLIP	23446348
MIRT507642	hsa-miR-155-3p	PAR-CLIP	23446348
MIRT371382	hsa-miR-4799-5p	PAR-CLIP	23446348
MIRT507640	hsa-miR-4701-5p	PAR-CLIP	23446348
MIRT507641	hsa-miR-588	PAR-CLIP	23446348
MIRT507639	hsa-miR-3685	PAR-CLIP	23446348
MIRT478884	hsa-miR-6882-5p	PAR-CLIP	23592263
MIRT478883	hsa-miR-4773	PAR-CLIP	23592263
MIRT478882	hsa-miR-300	PAR-CLIP	23592263
MIRT478881	hsa-miR-381-3p	PAR-CLIP	23592263
MIRT478880	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT215288	hsa-miR-758-5p	PAR-CLIP	23592263
MIRT478879	hsa-miR-5186	PAR-CLIP	23592263
MIRT215289	hsa-miR-3148	PAR-CLIP	23592263
MIRT215290	hsa-miR-6124	PAR-CLIP	23592263
MIRT478878	hsa-miR-323b-5p	PAR-CLIP	23592263
MIRT478877	hsa-miR-410-5p	PAR-CLIP	23592263
MIRT478876	hsa-miR-494-5p	PAR-CLIP	23592263
MIRT238468	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT478875	hsa-miR-5687	PAR-CLIP	23592263
MIRT165879	hsa-let-7a-3p	PAR-CLIP	23592263
MIRT165880	hsa-let-7b-3p	PAR-CLIP	23592263
MIRT165881	hsa-let-7f-1-3p	PAR-CLIP	23592263
MIRT165887	hsa-miR-98-3p	PAR-CLIP	23592263
MIRT215291	hsa-miR-6833-5p	PAR-CLIP	23592263
MIRT478874	hsa-miR-4752	PAR-CLIP	23592263
MIRT165929	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT165893	hsa-miR-15b-5p	PAR-CLIP	23592263
MIRT165904	hsa-miR-424-5p	PAR-CLIP	23592263
MIRT165883	hsa-miR-15a-5p	PAR-CLIP	23592263
MIRT165947	hsa-miR-6838-5p	PAR-CLIP	23592263
MIRT165908	hsa-miR-497-5p	PAR-CLIP	23592263
MIRT165896	hsa-miR-195-5p	PAR-CLIP	23592263
MIRT165884	hsa-miR-16-5p	PAR-CLIP	23592263
MIRT215381	hsa-miR-503-5p	PAR-CLIP	23592263
MIRT165944	hsa-miR-5197-5p	PAR-CLIP	23592263
MIRT215383	hsa-miR-646	PAR-CLIP	23592263
MIRT165941	hsa-miR-4690-3p	PAR-CLIP	23592263
MIRT165946	hsa-miR-5685	PAR-CLIP	23592263
MIRT478868	hsa-miR-4750-3p	PAR-CLIP	23592263
MIRT478873	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT478872	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT478871	hsa-miR-4736	PAR-CLIP	23592263
MIRT165939	hsa-miR-4524a-5p	PAR-CLIP	23592263
MIRT165945	hsa-miR-4524b-5p	PAR-CLIP	23592263
MIRT165937	hsa-miR-4256	PAR-CLIP	23592263
MIRT165948	hsa-miR-7150	PAR-CLIP	23592263
MIRT165930	hsa-miR-374b-3p	PAR-CLIP	23592263
MIRT165891	hsa-miR-107	PAR-CLIP	23592263
MIRT165888	hsa-miR-103a-3p	PAR-CLIP	23592263
MIRT478870	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT478869	hsa-miR-5694	PAR-CLIP	23592263
MIRT165931	hsa-miR-1179	PAR-CLIP	23592263
MIRT215351	hsa-miR-329-5p	PAR-CLIP	23592263
MIRT215297	hsa-miR-5697	PAR-CLIP	23592263
MIRT165936	hsa-miR-4310	PAR-CLIP	23592263
MIRT165949	hsa-miR-7157-5p	PAR-CLIP	23592263
MIRT478868	hsa-miR-4750-3p	PAR-CLIP	23592263
MIRT165932	hsa-miR-1184	PAR-CLIP	23592263
MIRT312931	hsa-miR-4755-3p	PAR-CLIP	23592263
MIRT312939	hsa-miR-190a-3p	PAR-CLIP	23592263
MIRT215353	hsa-miR-1297	PAR-CLIP	23592263
MIRT215349	hsa-miR-26a-5p	PAR-CLIP	23592263
MIRT215350	hsa-miR-26b-5p	PAR-CLIP	23592263
MIRT215355	hsa-miR-4465	PAR-CLIP	23592263
MIRT215352	hsa-miR-639	PAR-CLIP	23592263
MIRT165937	hsa-miR-4256	PAR-CLIP	23592263
MIRT312932	hsa-miR-5006-5p	PAR-CLIP	23592263
MIRT478867	hsa-miR-6083	PAR-CLIP	23592263
MIRT449110	hsa-miR-320a	PAR-CLIP	22100165
MIRT449109	hsa-miR-320b	PAR-CLIP	22100165
MIRT449108	hsa-miR-320c	PAR-CLIP	22100165
MIRT449107	hsa-miR-320d	PAR-CLIP	22100165
MIRT449106	hsa-miR-4429	PAR-CLIP	22100165
MIRT449105	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT017940	hsa-miR-335-5p	PAR-CLIP	22100165
MIRT449104	hsa-miR-9-3p	PAR-CLIP	22100165

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	18391022
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	16940180
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	16940180
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	18391022, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	18391022
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006986	Process	Response to unfolded protein	IEA
GO:0016604	Component	Nuclear body	IDA	18391022
GO:0016604	Component	Nuclear body	IEA
GO:0034976	Process	Response to endoplasmic reticulum stress	IDA	18391022
GO:0042711	Process	Maternal behavior	IEA
GO:0045732	Process	Positive regulation of protein catabolic process	IDA	18391022
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	16940180
GO:1900102	Process	Negative regulation of endoplasmic reticulum unfolded protein response	IDA	18391022
GO:1902213	Process	Positive regulation of prolactin signaling pathway	IEA
GO:2000323	Process	Negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway	IEA

Other IDs

• MIM: 617109
• HGNC: 24050
• e!Ensembl: ENSG00000164463

Protein

• UniProt ID: Q8IUR6
• Protein name: CREB3 regulatory factor (Luman recruitment factor) (LRF)
• Protein function: Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.
• Sequence:

  MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYELDREMNYQQNPRDNFL
  SLEDCKDIENLESFTDVLDNEGALTSNWEQWDTYCEDLTKYTKLTSCDIWGTKEVDYLGL
  DDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSLFSVKQNPLPSSFPGKKITSR
  AAAPVCSSKTLQAEVPLSDCVQKASKPTSSTQIMVKTNMYHNEKVNFHVECKDYVKKAKV
  KINPVQQSRPLLSQIHTDAAKENTCYCGAVAKRQEKKGMEPLQGHATPALPFKETQELLL
  SPLPQEGPGSLAAGESSSLSASTSVSDSSQKKEEHNYSLFVSDNLGEQPTKCSPEEDEED
  EEDVDDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEV
  TSISSRKRGKRRYFWEYSEQLTPSQQERMLRPSEWNRDTLPSNMYQKNGLHHGKYAVKKS
  RRTDVEDLTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRL
  KKKAQYEANKVKLWGLNTEYDNLLFVINSIKQEIVNRVQNPRDERGPNMGQKLEILIKDT
  LGLPVAGQTSEFVNQVLEKTAEGNPTGGLVGLRIPTSKV

• Sequence length: 639

Pathways

Reactome:

CREB3 factors activate genes

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
DYSLEXIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	10673740		★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	10673740		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	32699331	Associate	★☆☆☆☆ Found in Text Mining only
Anemia Sickle Cell	Sickle cell anemia	Pubtator	32917636	Associate	★☆☆☆☆ Found in Text Mining only
Benign Prostatic Hyperplasia	Benign Prostatic Hyperplasia	BEFREE	21251909		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	34990474	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	21640721		★☆☆☆☆ Found in Text Mining only
Central Precocious Puberty	Central Precocious Puberty	BEFREE	3917500		★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	10673740		★☆☆☆☆ Found in Text Mining only
Chondrosarcoma	Chondrosarcoma	BEFREE	22847180		★☆☆☆☆ Found in Text Mining only
Chronic kidney disease stage 5	Kidney Disease	BEFREE	31280340		★☆☆☆☆ Found in Text Mining only
Chronic Kidney Diseases	Kidney Disease	BEFREE	29721634		★☆☆☆☆ Found in Text Mining only
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	21483000, 24584352, 27151266		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	31018810		★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	31280340, 31543511		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	31280340, 31543511		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	31280340, 32884101, 34340601	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	31280340, 35144939, 36284436	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	29721634, 31280340, 31543511		★☆☆☆☆ Found in Text Mining only
Gallbladder Carcinoma	Gallbladder cancer	BEFREE	31632547		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	27278737		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	27278737		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	27163161	Associate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	27163161	Associate	★☆☆☆☆ Found in Text Mining only
Kidney Failure Chronic	Kidney failure	Pubtator	31280340	Associate	★☆☆☆☆ Found in Text Mining only
Kidney Failure, Chronic	Kidney Failure	BEFREE	31280340		★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	10673740, 21483000		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of gallbladder	Gallbladder cancer	BEFREE	31632547		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	21251909		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	29729692		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	19942610, 21640721, 22847180		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	31018810		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	22847180, 27278737, 31209250		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	27455349, 31280340, 32190945, 32884101, 35606300	Associate	★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	31280340		★☆☆☆☆ Found in Text Mining only
Precocious Puberty	Precocious puberty	BEFREE	3917500, 6223935		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	21251909		★☆☆☆☆ Found in Text Mining only
Pyloric Stenosis, Hypertrophic	Congenital hypertrophic pyloric stenosis	GWASDB_DG	22306654		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	21590684		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	29729692		★☆☆☆☆ Found in Text Mining only