Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	152007
Gene name	GLI pathogenesis related 2
Gene symbol	GLIPR2
Synonyms (NCBI Gene)	C9orf19GAPR-1GAPR1gliPR 2
Chromosome	9
Chromosome location	9p13.3

173

Show/Hide all (173)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020504	hsa-miR-155-5p	Proteomics	18668040
MIRT022923	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT1021060	hsa-miR-1224-3p	CLIP-seq
MIRT1021061	hsa-miR-146b-3p	CLIP-seq
MIRT1021062	hsa-miR-147	CLIP-seq
MIRT1021063	hsa-miR-2467-3p	CLIP-seq
MIRT1021064	hsa-miR-3134	CLIP-seq
MIRT1021065	hsa-miR-3151	CLIP-seq
MIRT1021066	hsa-miR-3201	CLIP-seq
MIRT1021067	hsa-miR-3616-3p	CLIP-seq
MIRT1021068	hsa-miR-3620	CLIP-seq
MIRT1021069	hsa-miR-3673	CLIP-seq
MIRT1021070	hsa-miR-3911	CLIP-seq
MIRT1021071	hsa-miR-4310	CLIP-seq
MIRT1021072	hsa-miR-4436b-3p	CLIP-seq
MIRT1021073	hsa-miR-4447	CLIP-seq
MIRT1021074	hsa-miR-4472	CLIP-seq
MIRT1021075	hsa-miR-4685-5p	CLIP-seq
MIRT1021076	hsa-miR-4719	CLIP-seq
MIRT1021077	hsa-miR-4723-5p	CLIP-seq
MIRT1021078	hsa-miR-4728-5p	CLIP-seq
MIRT1021079	hsa-miR-4791	CLIP-seq
MIRT1021080	hsa-miR-491-5p	CLIP-seq
MIRT1021081	hsa-miR-644	CLIP-seq
MIRT1549255	hsa-miR-23a	CLIP-seq
MIRT1549256	hsa-miR-23b	CLIP-seq
MIRT1549257	hsa-miR-23c	CLIP-seq
MIRT1549258	hsa-miR-3646	CLIP-seq
MIRT1549259	hsa-miR-629	CLIP-seq
MIRT1021061	hsa-miR-146b-3p	CLIP-seq
MIRT2002535	hsa-miR-31	CLIP-seq
MIRT2002536	hsa-miR-3179	CLIP-seq
MIRT2002537	hsa-miR-3202	CLIP-seq
MIRT2002538	hsa-miR-323-5p	CLIP-seq
MIRT2002539	hsa-miR-876-3p	CLIP-seq
MIRT2235540	hsa-miR-1178	CLIP-seq
MIRT2235541	hsa-miR-140-5p	CLIP-seq
MIRT2235542	hsa-miR-150	CLIP-seq
MIRT2235543	hsa-miR-2054	CLIP-seq
MIRT1021063	hsa-miR-2467-3p	CLIP-seq
MIRT2002535	hsa-miR-31	CLIP-seq
MIRT2235544	hsa-miR-3121-5p	CLIP-seq
MIRT2002538	hsa-miR-323-5p	CLIP-seq
MIRT2235545	hsa-miR-3545-5p	CLIP-seq
MIRT1021067	hsa-miR-3616-3p	CLIP-seq
MIRT2235546	hsa-miR-377	CLIP-seq
MIRT1021072	hsa-miR-4436b-3p	CLIP-seq
MIRT2235547	hsa-miR-4460	CLIP-seq
MIRT2235548	hsa-miR-4536	CLIP-seq
MIRT2235549	hsa-miR-4675	CLIP-seq
MIRT2235550	hsa-miR-4711-5p	CLIP-seq
MIRT2235551	hsa-miR-4713-5p	CLIP-seq
MIRT1021078	hsa-miR-4728-5p	CLIP-seq
MIRT2235552	hsa-miR-4731-3p	CLIP-seq
MIRT2235553	hsa-miR-4741	CLIP-seq
MIRT2235554	hsa-miR-4801	CLIP-seq
MIRT2235555	hsa-miR-483-3p	CLIP-seq
MIRT2235556	hsa-miR-486-5p	CLIP-seq
MIRT2235557	hsa-miR-516a-3p	CLIP-seq
MIRT2235558	hsa-miR-532-3p	CLIP-seq
MIRT2002539	hsa-miR-876-3p	CLIP-seq
MIRT2442193	hsa-miR-1270	CLIP-seq
MIRT2442194	hsa-miR-3612	CLIP-seq
MIRT2442195	hsa-miR-4434	CLIP-seq
MIRT2442196	hsa-miR-4459	CLIP-seq
MIRT2442197	hsa-miR-4516	CLIP-seq
MIRT2442198	hsa-miR-4531	CLIP-seq
MIRT2442199	hsa-miR-4695-5p	CLIP-seq
MIRT2442200	hsa-miR-620	CLIP-seq
MIRT2442201	hsa-miR-650	CLIP-seq
MIRT2442202	hsa-miR-665	CLIP-seq
MIRT2539394	hsa-miR-1200	CLIP-seq
MIRT2539395	hsa-miR-1264	CLIP-seq
MIRT2539396	hsa-miR-1289	CLIP-seq
MIRT2539397	hsa-miR-2114	CLIP-seq
MIRT2539398	hsa-miR-2116	CLIP-seq
MIRT2539399	hsa-miR-216a	CLIP-seq
MIRT1549255	hsa-miR-23a	CLIP-seq
MIRT1549256	hsa-miR-23b	CLIP-seq
MIRT1549257	hsa-miR-23c	CLIP-seq
MIRT1021064	hsa-miR-3134	CLIP-seq
MIRT2539400	hsa-miR-3149	CLIP-seq
MIRT2539401	hsa-miR-3163	CLIP-seq
MIRT2539402	hsa-miR-3198	CLIP-seq
MIRT2002538	hsa-miR-323-5p	CLIP-seq
MIRT2539403	hsa-miR-346	CLIP-seq
MIRT2539404	hsa-miR-3607-3p	CLIP-seq
MIRT2539405	hsa-miR-3622a-5p	CLIP-seq
MIRT1549258	hsa-miR-3646	CLIP-seq
MIRT2539406	hsa-miR-3662	CLIP-seq
MIRT1021069	hsa-miR-3673	CLIP-seq
MIRT2539407	hsa-miR-3686	CLIP-seq
MIRT2539408	hsa-miR-4264	CLIP-seq
MIRT2539409	hsa-miR-4294	CLIP-seq
MIRT2539410	hsa-miR-4309	CLIP-seq
MIRT1021071	hsa-miR-4310	CLIP-seq
MIRT2539411	hsa-miR-4326	CLIP-seq
MIRT2539412	hsa-miR-4423-3p	CLIP-seq
MIRT2539413	hsa-miR-4534	CLIP-seq
MIRT1021075	hsa-miR-4685-5p	CLIP-seq
MIRT2539414	hsa-miR-4694-3p	CLIP-seq
MIRT2539415	hsa-miR-4699-5p	CLIP-seq
MIRT2539416	hsa-miR-4715-3p	CLIP-seq
MIRT2539417	hsa-miR-4716-5p	CLIP-seq
MIRT1021076	hsa-miR-4719	CLIP-seq
MIRT2539418	hsa-miR-4727-5p	CLIP-seq
MIRT2539419	hsa-miR-4763-5p	CLIP-seq
MIRT2539420	hsa-miR-4769-3p	CLIP-seq
MIRT2539421	hsa-miR-4778-5p	CLIP-seq
MIRT2539422	hsa-miR-4797-3p	CLIP-seq
MIRT2539423	hsa-miR-539	CLIP-seq
MIRT2539424	hsa-miR-548n	CLIP-seq
MIRT1549259	hsa-miR-629	CLIP-seq
MIRT2539425	hsa-miR-645	CLIP-seq
MIRT2539426	hsa-miR-671-5p	CLIP-seq
MIRT2002539	hsa-miR-876-3p	CLIP-seq
MIRT2539427	hsa-miR-885-5p	CLIP-seq
MIRT2539428	hsa-miR-944	CLIP-seq
MIRT2539394	hsa-miR-1200	CLIP-seq
MIRT2539395	hsa-miR-1264	CLIP-seq
MIRT2539396	hsa-miR-1289	CLIP-seq
MIRT2539397	hsa-miR-2114	CLIP-seq
MIRT2539398	hsa-miR-2116	CLIP-seq
MIRT2539399	hsa-miR-216a	CLIP-seq
MIRT2681638	hsa-miR-218	CLIP-seq
MIRT1549255	hsa-miR-23a	CLIP-seq
MIRT1549256	hsa-miR-23b	CLIP-seq
MIRT1549257	hsa-miR-23c	CLIP-seq
MIRT1021064	hsa-miR-3134	CLIP-seq
MIRT2539400	hsa-miR-3149	CLIP-seq
MIRT2539401	hsa-miR-3163	CLIP-seq
MIRT2539402	hsa-miR-3198	CLIP-seq
MIRT2681639	hsa-miR-320a	CLIP-seq
MIRT2681640	hsa-miR-320b	CLIP-seq
MIRT2681641	hsa-miR-320c	CLIP-seq
MIRT2681642	hsa-miR-320d	CLIP-seq
MIRT2002538	hsa-miR-323-5p	CLIP-seq
MIRT2539403	hsa-miR-346	CLIP-seq
MIRT2539404	hsa-miR-3607-3p	CLIP-seq
MIRT2539405	hsa-miR-3622a-5p	CLIP-seq
MIRT1549258	hsa-miR-3646	CLIP-seq
MIRT2539406	hsa-miR-3662	CLIP-seq
MIRT1021069	hsa-miR-3673	CLIP-seq
MIRT2539407	hsa-miR-3686	CLIP-seq
MIRT2539408	hsa-miR-4264	CLIP-seq
MIRT2539409	hsa-miR-4294	CLIP-seq
MIRT2539410	hsa-miR-4309	CLIP-seq
MIRT1021071	hsa-miR-4310	CLIP-seq
MIRT2539411	hsa-miR-4326	CLIP-seq
MIRT2539412	hsa-miR-4423-3p	CLIP-seq
MIRT2681643	hsa-miR-4429	CLIP-seq
MIRT2539413	hsa-miR-4534	CLIP-seq
MIRT2681644	hsa-miR-455-5p	CLIP-seq
MIRT2539414	hsa-miR-4694-3p	CLIP-seq
MIRT2539415	hsa-miR-4699-5p	CLIP-seq
MIRT2539416	hsa-miR-4715-3p	CLIP-seq
MIRT2539417	hsa-miR-4716-5p	CLIP-seq
MIRT1021076	hsa-miR-4719	CLIP-seq
MIRT2681645	hsa-miR-4720-3p	CLIP-seq
MIRT2539418	hsa-miR-4727-5p	CLIP-seq
MIRT2539419	hsa-miR-4763-5p	CLIP-seq
MIRT2539420	hsa-miR-4769-3p	CLIP-seq
MIRT2539421	hsa-miR-4778-5p	CLIP-seq
MIRT2539422	hsa-miR-4797-3p	CLIP-seq
MIRT2681646	hsa-miR-4804-3p	CLIP-seq
MIRT2539423	hsa-miR-539	CLIP-seq
MIRT2539424	hsa-miR-548n	CLIP-seq
MIRT1549259	hsa-miR-629	CLIP-seq
MIRT2681647	hsa-miR-636	CLIP-seq
MIRT2539425	hsa-miR-645	CLIP-seq
MIRT2539426	hsa-miR-671-5p	CLIP-seq
MIRT2002539	hsa-miR-876-3p	CLIP-seq
MIRT2539428	hsa-miR-944	CLIP-seq

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	11865038
GO:0000139	Component	Golgi membrane	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0010634	Process	Positive regulation of epithelial cell migration	IDA	23516513
GO:0010718	Process	Positive regulation of epithelial to mesenchymal transition	IDA	23516513
GO:0016020	Component	Membrane	IEA
GO:0019953	Process	Sexual reproduction	IBA
GO:0042803	Function	Protein homodimerization activity	IDA	15123429
GO:0070062	Component	Extracellular exosome	HDA	18570454, 19056867, 23533145
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IDA	23516513

MIM	HGNC	e!Ensembl
607141	18007	ENSG00000122694

Q9H4G4

Protein name

Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2)

PDB

1SMB , 4AIW , 5VHG

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00188	CAP	14 → 133	Cysteine-rich secretory protein family	Domain

Tissue specificity

TISSUE SPECIFICITY: Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney. {ECO:0000269|PubMed:12137952}.

Sequence

MGKSASKQFHNEVLKAHNEYRQKHGVPPLKLCKNLNREAQQYSEALASTRILKHSPESSR
GQCGENLAWASYDQTGKEVADRWYSEIKNYNFQQPGFTSGTGHFTAMVWKNTKKMGVGKA
SASDGSSFVVARYFPAGNVVNEGFFEENVLPPKK

Sequence length

154

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
SQUAMOUS CELL LUNG CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (9)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinogenesis	Carcinogenesis	Pubtator	24204846	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	24204846, 38022651	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathies	Diabetic neuropathy	Pubtator	23516513	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	BEFREE	23516513		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	23516513, 24204846		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	24204846	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	23516513	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	24204846		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal fibrosis	Renal fibrosis	BEFREE	23516513		★★★★★ ★☆☆☆☆ Found in Text Mining only

GLIPR2 (GLI pathogenesis related 2)