Gene Gene information from NCBI Gene database.
Entrez ID 149420
Gene name PDLIM1 interacting kinase 1 like
Gene symbol PDIK1L
Synonyms (NCBI Gene)
CLIK1LSTK35L2
Chromosome 1
Chromosome location 1p36.11
miRNA miRNA information provided by mirtarbase database.
566
miRTarBase ID miRNA Experiments Reference
MIRT003816 hsa-miR-373-3p Microarray 15685193
MIRT016218 hsa-miR-590-3p Sequencing 20371350
MIRT024137 hsa-miR-221-3p Sequencing 20371350
MIRT050716 hsa-miR-18a-5p CLASH 23622248
MIRT049117 hsa-miR-92a-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0004672 Function Protein kinase activity IBA
GO:0004672 Function Protein kinase activity IEA
GO:0004674 Function Protein serine/threonine kinase activity IEA
GO:0005515 Function Protein binding IPI 22939624, 25036637, 25416956, 28514442, 32296183, 32707033, 33961781
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610785 18981 ENSG00000175087
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N165
Protein name Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1-interacting kinase 1-like)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00069 Pkinase 8 327 Protein kinase domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in liver, kidney, pancreas, spleen, thymus and prostate. {ECO:0000269|PubMed:14631099}.
Sequence
Sequence length 341
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute Erythroblastic Leukemia Erythroblastic Leukemia BEFREE 23435965
★☆☆☆☆
Found in Text Mining only
Acute lymphocytic leukemia Lymphocytic Leukemia BEFREE 30841886
★☆☆☆☆
Found in Text Mining only
Adenomatous Polyposis Coli Multiple polyposis syndrome BEFREE 16335528, 25645927, 25735981, 30554113
★☆☆☆☆
Found in Text Mining only
Adult Medulloblastoma Medulloblastoma BEFREE 31406250, 31659253
★☆☆☆☆
Found in Text Mining only
Advanced Sleep-Phase Syndrome, Familial Advanced Sleep Phase Syndrome BEFREE 21324900
★☆☆☆☆
Found in Text Mining only
Anaplasia Anaplasia BEFREE 30535443
★☆☆☆☆
Found in Text Mining only
Anophthalmia with pulmonary hypoplasia Anophthalmia Pubtator 32029502 Associate
★☆☆☆☆
Found in Text Mining only
Aortic Valve Insufficiency Aortic Valve Insufficiency BEFREE 28105499
★☆☆☆☆
Found in Text Mining only
Arteriosclerosis Arteriosclerosis BEFREE 17255531
★☆☆☆☆
Found in Text Mining only
Astrocytoma Astrocytoma BEFREE 16520553, 31588710
★☆☆☆☆
Found in Text Mining only